• Title/Summary/Keyword: System Risk Analysis

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Impedance Parameter Variations at Intravenous (IV) Infiltration Using Bioelectrical Impedance: A Pilot Study

  • Kim, Jaehyung;Lee, Mansup;Baik, Seungwan;Kim, Gunho;Hwang, Youngjun;Jeon, Gyerok
    • Journal of Korea Multimedia Society
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    • v.20 no.10
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    • pp.1678-1688
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    • 2017
  • Infiltration is one of detrimental problems occurring in nursing or medical settings. Early detection of infiltration is essential to minimize the risk of injury from infiltration. To perform a preliminary study on the point of care and automated infiltration detection system, bioelectrical impedance was investigated using bioelectrical impedance analyzer. We would like to report experimental results that allow impedance parameters to effectively distinguish infiltration. Electrodes were attached to both sides of the transparent dressing on the fusion site where IV solution was being infused. Then, impedance parameters before and after infiltration were measured as a function of time and frequency. The experimental results are as follows. After infiltration was intentionally induced by puncturing the vein wall with a needle, the resistance gradually decreased with time. That is, when an alternating current having a frequency of 20 kHz was applied to the electrodes, the resistance gradually decreased with time, reflecting the accumulation of IV solution in the extracellular fluid since the current could not pass through the cell membrane. Impedance parameters and equivalent circuit model for human cell were used to examine the mechanism of current flow before and after infiltration, which could be used for early detection of infiltration.

A Study on Musculoskeletal Symptom and Pain related to Working Posture of Operation-Room Workers. (수술실 근무자의 업무수행 관련 근골격계 부담정도와 통증에 대한 연구)

  • Kim, Ji-Yeun;Jaung, Ae-Hwa
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.8
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    • pp.2906-2916
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    • 2010
  • Purpose : The purpose of this study was to identify musculoskeletal symptom and pain related working posture with operation-room workers. Methods: The subjects of this study were 73 people who were working from hospital operating-room. A questionnaire consisting of general characteristics, pain symptoms, and pain frequency was given. Objective working posture analysis was done by using REBA after recording moving images in hospital operating-rooms. Results: The result were as follows. The risk level of musculoskeletal symptom related working posture was high, and the management level was at the least 2; 'some management was required for musculoskeletal symptom'. The frequency of pain was 3~4 times/week and the severe pain were experienced from legs, neck, and shoulder. The result of relation of general characteristics and pain were significant variable with sex, age, marital status, weight, past working history, average working time(hr/day), working style, and working department. Conclusion: These results contribute to a better understanding of operation-room workers have high possibility of musculoskeletal disease and are severe musculoskeltal pain related working posture.

Higher dextrose delivety via TPN related to the development of hyperglycemia in non-diabetic critically ill patients

  • Lee, Ho-Sun;Koh, Shin-Ok;Park, Moo-Suk
    • Nutrition Research and Practice
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    • v.5 no.5
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    • pp.450-454
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    • 2011
  • The beneficial effects of total parenteral nutrition (TPN) in improving the nutritional status of malnourished patients during hospital stays have been well established. However, recent randomized trials and meta-analyses have reported an increased rate of TPN-associated complications and mortality in critically ill patients. The increased risk of complications during TPN therapy has been linked to the development of hyperglycemia, especially during the first few days of TPN therapy. This retrospective study was conducted to determine whether the amount of dextrose from TPN in the 1st week in the intensive care unit (ICU) was related to the development of hyperglycemia and the clinical outcome. We included 88 non-diabetic critically ill patients who stayed in the medical ICU for more than two days. The subjects were 65 ${\pm}$ 16 years old, and the mean APACHE (Acute Physiology and Chronic Health Evaluation) II score upon admission was 20.9${\pm}$7.1. The subjects received 2.3${\pm}$1.4 g/kg/day of dextrose intravenously. We divided the subjects into two groups according to the mean blood glucose (BG) level during the 1st week of ICU stay: <140 mg/dl vs ${\geq}$ 140 mg/dl. Baseline BG and the amount of dextrose delivered via TPN were significantly higher in the hyperglycemia group than those in the normoglycemia group. Mortality was higher in the hyperglycemia group than in the normoglycemia group (42.4% vs 12.8%, P=0.008). The amount of dextrose from TPN was the only significant variable in the multiple linear regression analysis, which included age, APACHE II score, baseline blood glucose concentration and dextrose delivery via TPN as independent variables. We concluded that the amount of dextrose delivered via TPN might be associated with the development of hyperglycemia in critically ill patients without a history of diabetes mellitus. The amount of dextrose in TPN should be decided and adapted carefully to maintain blood glucose within the target range.

Establishing the Importance Institution for Prevention of Human Error (인적오류 예방을 위한 제도의 상대적 중요도 분석)

  • Moon, Woo-Choon;Kim, Woong-Yi
    • Journal of Advanced Navigation Technology
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    • v.17 no.4
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    • pp.377-385
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    • 2013
  • Since the late 1950s, concerted efforts to reduce the accident rate in aviation have yielded unprecedented levels of safety. Although, the overall accident rate has declined considerably over the years, unfortunately reductions in human error-related accidents in aviation have failed to keep pace with the reduction of accidents due to environmental and mechanical factors. Today, a very large percentage of all aviation are attributable, directly or indirectly, to some form of human error. As a result of many study, a range of prevention of human error have been developed. but each of kind is lack of a precision, effectiveness and seem to be considered for aspect of deficiency as an systematic accessibility. So, we're going to analysis the most effective and systematic prevention of human error and study on consolidating method for human error and aviation safety. In this study, several alternatives for the prevention of human errors a priority to understand and solve problems by identifying the implications for human error to be presented.

Posture Analysis of Workers in an Excavator Factory Using 3D Human Simulation (3D 작업자 시뮬레이션을 이용한 굴삭기 생산공정 작업자 자세분석)

  • Moon, Dug-Hee;Baek, Seung-Geun;Zhang, Bing-Lin;Lee, Jun-Seok
    • Journal of the Korea Society for Simulation
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    • v.15 no.3
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    • pp.93-101
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    • 2006
  • Recently, work-related musculoskeletal disorders (WMSDs) become a hot issue in the industrial fields. To prevent the potential risk of workers, various approaches have been adopted. One of the approaches is to improve the design of product, that of jig (or fixture) and that of workstation in the early stage of the development. 3D simulation technology is known as the powerful method for detecting such problems before constructing the workstation, because it is possible to evaluate the posture of worker using 3D models in a cyber space. It enables to find the unexpected problems and save the time and cost for redesign and rework. This paper introduces a 3D simulation case study of workers in an excavator factory. 3D models of products, jigs were developed with CATIA. The assembly processes were animated in IGRIP and DPM. Finally the various postures of worker were simulated using Human. As a result, some postures were analysed as the risky jobs and the result of simulation was used to improve the system.

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A Study on the Agency Theory and Accounting (에이전시이론과 회계감사에 관한 연구)

  • 공해영
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.12 no.20
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    • pp.123-138
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    • 1989
  • The primary objective of the agency research in the game theory lives in the maintenance of Pareto is optimal condition for the optimal incentive contract. The basic concepts which are related to this objective are reviewed in connection with the general assumptions to model it, the moral hazard and adverse selection which arised from the information asymmetry, and finally the problem of risk distribution. The demand for auditing and the role of auditor have been addressed by ASOBAC. Issues which an auditor is explicitly introduced in a principal-agent framework have been addressed in this paper. These issues must be confronted to appropriately with the auditor, and to achieve an adequate understanding of optimal confronting arrangement with the auditor. The first step in introducing an auditor into this analysis is to examine the game-theoretic foundation of such a expended agency model. The Mathematical program formulated may not yield solution that are resonable. This arises because the program may call for the auditor and manager to play dominated Nash equilibra in some subgame. The nontrivial natures of the subgame implies that randomized strategies by the auditor and manager nay be of crucial importance. The possibilities for overcoming the randomized strategy problem were suggested; change the rule of the game and or impose covexity condition. The former seems unjustifiable in on auditing context, and the latter promising but difficult to achieve. The discussion ended with an extension of the revelation principle to the owner manager-auditor game, assuming strategies. An examination of the restriction and improvement direction of the basic concept of agency theory was addressed in the later part of this paper. Many important aspects of auditor incentives are inherently multiple-agent, multiple-period, multiple-objectine, phenomena and require further analyses and researches.

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Application of Quantum-dot Nanocrystals for Cyanobacterial Toxin-Microcystin Detection (나노크리스탈 Quantum-dot을 적용한 남조류 독소 Microcystin 탐지 연구)

  • Lee, Jinwook;Yu, Hye-Weon;Kim, In S.
    • Journal of Korean Society on Water Environment
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    • v.23 no.5
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    • pp.705-711
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    • 2007
  • Green quantum-dot nanocrystal (QD525) with anti-microcystin monoclonal antibody was applied for detection of microcystin, a monocyclic peptide hepatotoxin, extracted from the culture of Microcystis aeruginosa. The presence of microcystin in the cell lysate was verified by HPLC analysis with UV absorbance at 238 nm. Microcystis cell extract exhibited fluorescence emission spectra, which peak was around 460 nm because of their complex organic substances. When a spherical QD525 antibody conjugates (10~20 nm in diameter) were bound to the microcystins in the Microcystis cell lysate, the fluorescence intensity of the primary peak at 525 nm diminished while the secondary emission peak at 460 nm slightly increased intensities. It is due to energy transfer from the primary (major) to the secondary (minor) peak, resulting from physical deformation of QD525 and different environmental factors. On the other hand, other cell extracts did not show any fluorescence emission change. This study is very available for detecting and monitoring the microcystin because it is one step assay without washing step and portable spectrophotometer makes on-site measurement possible. For health risk assessment of the microcystin, the reliable and rapid system to detect and quantify microcystin is seriously required.

Assessments of the Nutrient Losses in the Sloped Farm Land (경사지 밭토양에서의 양분유실량 평가)

  • Jung, Pil-Kyun;Eom, Ki-Cheol;Ha, Sang-Keon;Zhang, Yong-Seon;Hur, Seung-Oh
    • Korean Journal of Soil Science and Fertilizer
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    • v.42 no.spc
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    • pp.47-50
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    • 2009
  • Nutrient losses, especially nitrogen and phosphorus, in agricultural runoff can contaminate surface and ground water, leading to eutrophication. Thus, erosion control is crucial to minimizing nutrient losses from agricultural land. Assessments of various erosion control practices were carried out under various cropping system, soil management practices, and slope conditions by means of a lysimeter study and under artificial rainfall. Soil and nutrient losses were monitored in a small agricultural field to evaluate the soil conservation practices. Nutrient losses occur in runoff and leachate (dissolved nutrient) and in sediments (particulate nutrient). Dissolved nitrates accounted for the majority (about 90%) of nitrate transport within the soil. Particulate phosphate in sediments represented the majority (60% to 67%) of phosphate transport. Recently, engineering and agronomic erosion-control practices haver been used to reduce erosion problems in fields on slopes. These practices reduced soil loss, runoff, and nutrient loss to 1/6, 1/2,and 1/3 their original levels, respectively. Bioavailable particulate phosphate in sediments represents a variable but longterm source of phosphate for algae. Dissolved nitrate and phosphate are immediately available for algal uptake, so reducing fluxes of these nutrients should also reduce the risk of eutrophication.

A Study on Enhancement of Orbit Prediction Precision for Space Objects Using TLE (TLE를 이용한 우주물체 궤도예측 정밀도 향상 연구)

  • Yim, Hyeonjeong;Jung, Ok-Chul;Chung, Dae-Won
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.42 no.3
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    • pp.270-278
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    • 2014
  • This paper describes an improvement of space objects orbit prediction. To screen possible collisions between operational satellites and space objects, the TLE (Two-Line Element) was used as pseudo-measurement and than the orbit determination and orbit prediction were performed through the flight dynamics system. For determining the orbits, the state vectors were assumed by a series of TLEs within a certain period. The propagation error was analyzed according to the fitting period and a number of pseudo-observations. In order to find out the improvement of orbit prediction with the proposed method, KOMPSAT-2, 3 having the precise orbit in the meter-level range were first applied. Then the result applied to space objects under the same conditions was analyzed. As a result of the RMS error comparison with the orbit prediction of space object, the precision of orbit prediction was improved by approximately 90% for seven days prediction. The improved orbit prediction of space objects can be utilized in the daily analysis for initial screening of the close space objects at high risk.

Development of Vancomycin Initial Dosage Guidelines to Achieve New Target Ranges (Vancomycin 초기 투여 용량 개선 방안)

  • Yoo, Jae-Young;Kim, Jung-Hyun;Lee, Yong-Won;Kim, Eun-Yeong;Sohn, Kie-Ho
    • Korean Journal of Clinical Pharmacy
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    • v.20 no.3
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    • pp.221-228
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    • 2010
  • In 2009, American Journal of Health-System Pharmacy (AJHP) recommended that targeting vancomycin trough concentrations of 10 mg/L or more because of therapeutic failure and potential risk of developing vancomycin resistance. Therefore, new dosage guidelines that could achieve to these higher target were needed. The aims of this study were to develop dosage guidelines targeting new vancomycin trough concentration and to evaluate the performance of these new guidelines. All data analysis were performed using NONMEM(R). Population pharmacokinetic model was first developed from vancomycin dosage and concentration data collected retrospectively during routine therapeutic drug monitoring in 441 patients, then new vancomycin dosage guidelines were developed by using the model to predict vancomycin trough and peak concentrations in a simulated dataset. The estimates, such as, vancomycin concentration trough level, time to achieve target level, mean error were performed to evaluate and compare difference between conventional dosage and new dosage guidelines. The proposed dosage guidelines were predicted to achieve 43.5% of vancomycin trough level within 10~20 mg/L, which is significantly higher than current guidelines (26.3%). Time to achieve target trough level was 19.4 hours in new guidelines comparing to 93.1 hours in the conventional dosage. Thus, new vancomycin dosage guidelines have been developed to achieve new target trough concentrations earlier and more consistently than conventional guidelines.