• Journal of Microbiology and Biotechnology
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• v.22 no.11
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• pp.1494-1500
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• 2012

Fermentation with filamentous fungi in a bioreactor is a complex dynamic process that is affected by flow conditions and the evolution of the rheological properties of the medium. These properties are mainly affected by the biomass concentration and the morphology of the fungus. In this work, the rheological properties of a fermentation with the fungus Beauveria bassiana under different hydrodynamic conditions were studied and the rheological behavior of this broth was simulated through a mixture of carboxymethyl cellulose sodium and cellulose fibers (CMCNa-SF). The bioreactor was a 10 L CSTR tank operated at different stir velocities. Rheological results were similar at 100 and 300 rpm for both systems. However, there was a significant increase in the viscosity accompanied by a change in the consistence index, calculated according to the power law model, for both systems at 800 rpm. The systems exhibited shear-thinning behavior at all stir velocities, which was determined with the power law model. The mixing time was observed to increase as the cellulose content in the system increased and, consequently, the efficiency of mixing diminished. These results are thought to be due to the rheological and morphological similarities of the two fungal systems. These results will help in the optimization of scale-up production of these fungi.

• Bulletin of the Korean Chemical Society
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• v.35 no.6
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• pp.1806-1808
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• 2014

We report the successful preparation of gold nanoparticles (Au NPs) using a novel electroreduction process, which is simple, fast, and environmentally friendly (toxic chemicals such as strong reducing agents are not required). Our process allows for the mass production of Au NPs and adequate particle size control. The Au NPs prepared show high biocompatibility and are non-toxic to healthy human cells. By applying radio-frequency (RF) ablation, we monitored the electro-hyperthermia effect of the Au NPs at different RFs. The Au NPs exhibit a fast increase in temperature to $55^{\circ}C$ within 5 min during the application of an RF of 13 MHz. This temperature rise is sufficient to promote apoptosis through thermal stress. Our work suggests that the selective Au NP-mediated electro-hyperthermia therapy for tumor cells under an RF of 13 MHz has great potential as a clinical treatment for specific tumor ablation.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.15 no.6
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• pp.83-88
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• 2016

Over the last five years, 568 people have died while hiking according to 2015 statistics from the public safety ministry. Among those deaths, approximately 33% were due to loss of footing or falling. In this respect, the highly advanced functions of hiking boots should be considered to prevent these unfortunate accidents. For example, by utilizing the Internet of Things (IoT) and Information and Communications Technology (ICT), hiking boots equipped with a Global Positioning System (GPS) or vital signs monitoring systems should be considered. In addition, many challenges remain for the production of 3D printed hiking boots, because the functions of hiking boots are variable, which is important when handling changing terrains and situations. The design of customized hiking boots was introduced in this paper, and 3D printing applications for midsoles using a Porous Polymer Printing (PPP) method was also suggested to verify the possibility of manufacturing hiking boots.

• Journal of Korea Foundry Society
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• v.17 no.2
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• pp.170-179
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• 1997

A noble technique has been developed for fabricating in situ formed $TiC_p/Al$ composites. In this process, fairly stable TiC particles were in situ synthesized in liquid aluminum by the interfacial reaction between an Al-Ti melt and SiC, which is a comparatively unstable carbide from the view-point of thermodynamics. It is possible in the present process to generate TiC particles of nearly 1 ${\mu}m$ in diameter, even utilizing SiC of 14 ${\mu}m$ as raw material. However, the dispersion behavior of TiC particles in the matrix depends on the size of the raw material SiC. Decomposing finer SiC makes the dispersion of TiC particles more uniform and the mechanical properties of composites are improved accordingly. The structure of in situ composites and their mechanical properties are affected by the fabrication temperature and the stirring time. It has been found that the most suitable condition for fabrication should be applied depending on the size of the raw material, even if the same kinds of carbide are used. Furthermore, although Al-Ti-Si system intermetallic compounds are detected in a $TiC_p/Al-Si$ composite which is fabricated by conventional melt-stirrng method, these compounds can not be observed in a $TiC_p/Al-Si$ composite made by this in situ production method. Hence the mechanical properties of the in situ $TiC_p/Al-Si$ composite are superior to those of the conventional $TiC_p/Al-Si$ composites.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.7 no.2
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• pp.45-51
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• 2008

The objective of this study is to develop an automatic object changer unit to improve processing problems existed in the conventional horizontal machining center. In order to perform this objective, a upward and downward traverse unit in which a unit that consists of a motor and reducer, chain and sprocket wheel, and upper and lower base employed in an automatic object changer unit performs sliding contact motion in a frame was designed. To achieve this design, constraint conditions for the upward and downward traverse unit first designed. Then, an operation mechanism was designed and that was introduced as a sum of kinetic energy for the sprocket wheel and upper and lower base based on the moment of inertia, which is the kinetic energy of the converted upward and downward traverse unit in the side of the reducer. In addition, The work required to rotate the converted upward and downward traverse unit in the side of the reducer by one revolution can be calculated using the sum of work that is required in the sprocket wheel and upper and lower base that is a part of the upward and downward traverse unit. Furthermore, the converted equation of motion in the side of the motor can be introduced using the equation of motion using the converted upward and downward traverse unit in the side of the motor. Then, Then, a proper motor can be determined using predetermined specifications employed in the motor and several parameters in the upward and downward traverse unit in order to verify such predetermined specifications. Also, a design of a horizontal traverse unit that performs sliding motion on a upward and downward traverse unit and simulation that verifies the results of this design are required as a future study.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.34 no.7
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• pp.905-910
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• 2010

Exhaust manifolds are the first structures to be developed by hydroforming; mass production of exhaust manifolds by this method will be possible soon. This is obviously related with tight emission regulation induced by environmental problems commonly for both domestic and worldwide and standards, thus evoking its solution for domestic automakers. Compared to conventional cast products, thin-gauge tubular hydroformed exhaust manifold have superior features; for example, in the hydroformed exhaust manifold, gas decomposition during the cold-start period of the engine is reduced by lowering the heat sink, and manufacturing process is simplified since less welding is involved. The aim of this study is to develop a hydroformed exhaust manifold; the study deals with the components, the hydroforming process, and tool design of the manifolds. The performance of the exhaust system is evaluated by performing flow analysis, heat-transfer analysis, heat-stress analysis, and fatigue analysis by using a computer.

• Journal of Korean Society of Water and Wastewater
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• v.22 no.3
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• pp.337-342
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• 2008

A population growth and industry advances are increasing the demand for water while improving the quality of life. By turning seawater into freshwater it is an alternative for the water shortage problem. The study analyzes the orders and makes suggestions on the outlook of an enterprise that can supply desalination plants both inside and outside the country. It compares the production capacity of enterprises in the desalination industry who deal with the thermal and RO methods. We compare 7 enterprises in the thermal method which includes Doosan Heavy Industries, and the top 10 enterprises in the RO method which includes General Electric Corp. Now that the markets in the Middle East have opened and markets in other regions are gradually growing, demand for water will grow especially in developing countries that are in the process of industrialization. Also, the market share of thermal method desalination has been falling, gradually, because too much energy is spent during the process. On the other hand, the market share of the RO method will rise from 37% in 2005 to 57% in 2015. Recently, the desalination market shows that changing from thermal method to RO method is the trend in the Middle East. Growth and demand in other regions are growing at the same pace as the Middle East. Due to this trend, if the RO system, which is highly effective and uses less energy, were to be continuously developed it would be possible to supply water using sea water and would be a viable alternative water resource.

• Phonetics and Speech Sciences
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• v.9 no.3
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• pp.25-32
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• 2017

Besides their effect on the f0 contour of the following vowel, Korean stops are undergoing a sound change in which a partial or complete consonantal merger on voice onset time (VOT) is taking place between aspirated and lax stops. Many previous studies on sound change have mainly focused on group-normative effects, that is, effects that are representative of the population as a whole. Few systematic quantitative studies of change in adult individuals have been carried out. The current study examines whether the sound change holds for individual speakers. It focuses on inter-speaker and intra-speaker variability on sound change in contemporary Korean. Speech data were collected for thirteen Seoul Korean speakers studying abroad in America. In order to minimize the possible effects of speech production, socio-phonetic factors such as age, gender, dialect, speech rate, and L2 exposure period were controlled when recruiting participants. The results showed that, for nine out of thirteen speakers, the consonantal merger is taking place between the aspirated and lax stop in terms of VOT. There were also intra-speaker variations on the merger in three aspects: First, is the consonantal (VOT) merger between the two stops is in progress or not? Second, are VOTs for aspirated stops getting shorter or not (i.e., the aspirated-shortening process)? Third, are VOTs for lax stops getting longer or not (i.e., the lax-lengthening process)? The results of remarkable inter-speaker and intra-speaker variability indicate a synchronous speech sound change of the stop system in contemporary Korean. Some speakers are early adopters or active propagators of sound change whereas others are not. Further study is necessary to see whether the inter-speaker differences exceed intra-speaker differences in sound change.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.37 no.7
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• pp.669-674
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• 2013

A three-dimensional hydrogel scaffold has been proposed for the effective production of biomimetic intestinal villi to reduce ethical and cost problems caused by animal testing in pharmaceutical development. This study explores an experimental approach to develop a new technique based on laser machining and microdrilling processes to produce a plastic mold for the fabrication of a three-dimensional hydrogel scaffold. For process optimization, both the laser machining and the microdrilling experiments are conducted by varying the experimental conditions, and structural characterization of the mold and intestinal villi were performed using SEM (scanning electron microscope) and OM (optical microscope) images. Polycarbonate (PC) was used as a candidate material. The experimental results show that intestinal villi can be fabricated by both laser and microdrilling machining processes.

• Korean Journal of Environmental Agriculture
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• v.25 no.3
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• pp.247-256
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• 2006

This study has been conducted for the process of food wastes disposal using surplus capacity of established sewage treatment plant by co-digestion of fermented food wastes and sewage sludge after thermophilic acid fermentation of food wastes. The co-digestion of thermophilic acid fermented food wastes and sewage sludge was performed by semi-continous method in mesophilic anaerobic digestion reactor. It showed great digestion efficiency as the average SCOD and VS removal efficiency in organic loading rate 3.30g VS/L.d. were 74.2% and 73.6%, and the gas production rate and average methane content were 0.440 L/g $VS_{add}.d$ and 66.5%, respectively. Based on the results of this study, the co-digestion of thermophilic acid fermented food wastes and sewage sludge in sewage treatment plant is able to improve treatment efficiency of anaerobic digestion reactor and to dispose food wastes simultaneously, and was proved excellent economical efficiency comparing with any other treatment methods.