• Biomedical Science Letters
• /
• v.19 no.1
• /
• pp.25-31
• /
• 2013

Electrospun nanofibers are being widely used as a substratum for mammalian cell culture owing to their structural similarity to collagen fibers found in extracellular matrices of mammalian cells and tissues. Especially, development of diverse synthetic polymers has expanded use of electrospun nanofibers for constructing cell culture substrata. Synthetic polymers have several benefits comparing to natural polymer for their structural consistency, low cost, and capability for blending with other polymers or small molecules to enhance their structural integrity or add biological functions. PMGI (polymethylglutarimide) is one of the synthetic polymers that produced a rigid nanofiber that enables incorporation of small molecules, peptides, and gold nanoparticles through co-electrospinning process, during which the materials are fixed without any chemical modifications in the PMGI nanofibers by maintaining their activities. Using the phenomenon of PMGI nanofiber, here I introduce a construction method of a nanofiber substratum having cell-affinity function towards a pluripotent stem cell by incorporating a small molecule in the PMGI nanofiber.

• Journal of Adhesion and Interface
• /
• v.19 no.1
• /
• pp.5-12
• /
• 2018

The purpose of this study is to evaluate the adhesive properties of polyurethane mixed aqueous dispersions by omitting the primer, dealing with the preparation of skins for synthetic leather with excellent adhesion by omitting the pre-treatment process. The two-component mixed polyurethane water dispersion was prepared by synthesizing an ester-based polyurethane resin (PU-T) and a carbonate-based polyurethane resin (PU-C) to obtain the final resin. As a result of measuring the peel strength of the adhesive specimens omitting the pre-treatment agent, it was confirmed that the state adhesive strength (ethylene vinyl acetate (middle): $4.2kg_f/cm$ and rubber (outsole): $4.4kg_f/cm$) there was. This makes it possible to omit the pre-treatment process which has been indispensably used in the shoe manufacturing process, thereby reducing the process time and reducing the amount of volatile organic compounds (VOCs) generated in the pre-treatment product, resulting in environmentally advantageous.

• Journal of Conservation Science
• /
• v.35 no.6
• /
• pp.681-688
• /
• 2019

In this study, the characteristics of natural and synthetic adhesives used in woodcraft were evaluated. The pattern of deterioration of wood and adhesives according to changes in temperature and humidity were compared. For materials, one type of anlmal glue, three kinds of polyvinyl acetate adhesives, one type of epoxy adhesive and one type of zelkova wood were selected. Characteristics of physical and chemical characteristics, weather resistance and drying speed assessment were carried out. The adhesion characteristic evaluation showed that the adhesion strength of anlmal glue and one type of polyvinyl acetate adhesive were 6.54 N/㎟ and 7.01 N/㎟, pH meter of anlmal glue and polyvinyl acetate adhesives was pH 7.03 and pH 3.32-3.59 which were range of available as an adhesive. According to the test results of weather resistance, epoxy adhesives had the highest decreasing value in adhesion strength after deterioration. In the reversible test of the adhesive, it was found to be highly reversible in NaOH, a soluble solvent excluding epoxy, but attention is required when using the wood since it may show discoloration during processing.

• Journal of the Korean Graphic Arts Communication Society
• /
• v.30 no.1
• /
• pp.35-45
• /
• 2012

Polyacrylate dispersion(emulsion) as adhesive material was superior in quality such as preservation characteristics and reversibility. The tapes for repairing archival documents manufactured with four different types of formulation resulted in pH 7~8.8, soluble solid 50~52%, and viscosity 1,300~2,500 cps. Sample 4 of those was most excellent. Probably, sample 4 included inorganic materials such as MgO, silica gel, and zeolite. For selecting carrier of tape, tracing papers, were applied for manufacturing tapes and tested for adhesive strength and peel strength. Adhesive strength of tracing papers, was 3.1~3.8(N/10mm), 2.2~2.8(N/10mm), and 1.7-2.3(N/10mm), respectively. Peel strength was similar in all samples. To determine characteristic of conservation to the selected carriers, stability of deterioration was examined at conditions of $105^{\circ}C$ and $80^{\circ}C$ 65% for 7 days.

• Journal of the Korean Wood Science and Technology
• /
• v.30 no.1
• /
• pp.1-10
• /
• 2002

The aim of this research was to investigate the manufacturing possibility of the paper sludge-synthetic fiber-wood fiber composite. Three levels of the formulation of paper sludge, synthetic fiber and wood fiber (5:5:90, 15:15:70, 25:25:50), two types of adhesive (PMDI, urea-formaldehyde resin) and three levels of density(0.7, 0.8, 0.9) were designed. From the test result, composites with similar or better properties, when compared with commercial fiberboard, appeared to be possible by the addition of up to 30~50% paper sludge and synthetic fiber into wood fiber.

• Korean Journal of Heritage: History & Science
• /
• v.49 no.4
• /
• pp.114-125
• /
• 2016

Lacquer is one of the most widely used natural resin in East Asia since Neolithic Age. As a major ingredient of lacquerware, lacquer is waterproof, insect-proof and rot-proof to be durable and anti-abrasion, generally utilized for mainly painting purpose. According to lacquerware excavated from several sites of Japan and China, lacquerware seems to appear in Neolithic Age. On the other hand in case of excavation research in Korea, lacquerwares are found after the Bronze Age. The initial purpose of lacquer is estimated to be adhesive, regarding the literatures mentioning bitumen(Yeoksceong ), animal glue(Kyeo) and egg alumen(Nanbaek). Especially piece of jar coffin unearthed in Pyeongtaek Daechu-ri site had trace of restoration by lacquer and hemp as an evidence of lacquer for adhesion in Pre-Three Kingdoms period. Since then a trend to restore the broken ceramics with lacquer and decorate with golden foil lasted especially in Joseon Dynasty. In the field of gold plated lacquer method, mother-of-pearl inlaying technique for lacquerware and restoration of buildings, lacquer is still used as adhesive. Due to matter of reversibility lacquer is being avoided for conservation and restoration of cultural heritage. Lacquer as a traditional material for adhesive since ancient times, however, has advantage in adhesion strength and durability. Because synthetic resin adhesive has problem of emission of volatile organic compounds and aging over time, lacquer receives attention recently. On the contrary, by combination adhesive from mixing lacquer and animal glue, already proved the possibility of applicability and chemical modification. A research to utilize lacquer as modern paint or functional material is also conducted continuously also in China and Japan. To put traditional material into practical use and modernize, chemical research from the molecular level of the lacquer is necessary in the near future.

• Applied Chemistry for Engineering
• /
• v.29 no.4
• /
• pp.399-404
• /
• 2018

This study compared the tackiness and adhesion of different tire tread compounds and rubber cements before and after vulcanization. The tackiness of natural rubber (NR) cement was the highest for all tread compounds before vulcanization, and the decrease in tackiness of NR cements over time was smaller than that of synthetic rubber cements. The tackiness before vulcanization was affected by the glass transition temperature of the rubber used in the cement and the decrease in tackiness over time of NR was smaller compared to that of using the synthetic rubber. The adhesion of NR-based cements after vulcanization was high for NR tread compounds but low for synthetic rubber tread compounds. On the contrary, the adhesion of emulsion (SBR) and solution SBR cements was high on all tread compounds which was shown to be higher when the rate of vulcanization of cement rubber was lower.

• Journal of Conservation Science
• /
• v.34 no.5
• /
• pp.379-385
• /
• 2018

This study examined the condition of degraded plastic artifacts and conducted materials assessments for conservation treatment. The properties and bond characteristics of five types of adhesives(EVA, PVAc, Cyanoacrylate) were evaluated to select the adhesive most suitable for conservation treatment. The degradation of plastic artifacts caused cracks, peelings, and surface warping. According to the FT-IR analysis, the synthetic resin used in the artifact was estimated to EVA type. The properties of the adhesives were evaluated through acidity, and hardness measurements. The results showed that acidity varies with the type of adhesive, and that the hardness of PVAc was higher than those of EVA. On comparing the bond characteristics of the samples after artificial degradation, it was found that PVAc and Cyanoacrylate increased the chromaticity and hardness of the samples, while EVA was the most stable with relatively little change. Thus, EVA was confirmed to be the most suitable materials for conservation treatment of degraded plastic artifacts. In this study, as the experiment of treatment materials based on actual artifact, it is expected that it could be used a basis research for conservation treatment of plastic artifacts.

• BMB Reports
• /
• v.31 no.5
• /
• pp.515-518
• /
• 1998

Adhesive interaction of the platelet glycoprotien IIb-IIIa (GP IIb-IIIa) with a plasma protein, such as fibrinogen, plays an important role in thrombosis and hemostasis. The specific sequence Arg-Gly-Asp (RGD) is critical for the binding of fibrinogen to platelet. To examine and characterize the GP IIb-IIIa antagonist from natural sources, we have developed a simple enzyme-linked immunosorbant assay (ELISA) system. The GP IIb-IIIa complex was purified to homogeneity from platelet Iysates by the combination of two affinity chromatographic methods using the synthetic RGD peptide (GRGDSPK)-immobilized Sepharose and wheat germ lectin-Sepharose. The synthetic peptide GRGDSP inhibits GP IIb-IIIa binding to immobilized fibrinogen with an $IC_{50}$ of $1.5\;{\mu}M$. Venoms of three different snake species and a Korean scolopendra extract have strong antagonistic activities for the binding of human fibrinogen to the platelet GP IIb-IIIa complex. The $IC_{50}$ values of the snake venom s and scolopendra were in the range of $5.5\;{\mu}g$ to $60\;{\mu}g$. These results provide meaningful information for developing antiplatelet agents.

• Korea Science and Art Forum
• /
• v.37 no.5
• /
• pp.239-248
• /
• 2019

This study started from the need to improve one of shortcomings of synthetic PVAc adhesives - potential physical harm and environmental hazards to the workers or their users. As a matter of fact, PVAc adhesives are currently mainly used because of their convenience and economy for the production of woodcrafts. The purpose of this study was to develop natural adhesives through research on natural adhesives in step with the current increase of societal attention to environmental friendliness and rapid surge in their demand in the face of such problems. So, the study attempted research on the bases to develop natural adhesives for woodcraft, using cellulose extracts from wood - natural adhesive material. The findings of the study were as follows. Firstly, natural adhesives showed the improved effect in the field of adhesive strength, a basic physical property by 0.2 - 4 times compared with the existing materials and the study confirmed they had the similar or stable pH value. Besides, they had good reversibility, demonstrating their basic physical property as a natural adhesive for woodcraft. While, their durability to ultraviolet ray degradation also showed an excellent result value being better by 1.5 - 8.5 times than the existing materials. The study expects natural adhesives with improved and better performances compared with the existing materials could be developed, if further research on adhesive strength, antibiosis, conservative property were to continue by developing refinery technology for cellulose extracts from wood and rendering the functionality to them.