• Archives of Pharmacal Research
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• 제12권3호
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• pp.207-213
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• 1989

This study was performed to investigate the mechanism of in vitro cytotosic actions of polyacetylenes which are panaxydol, panaxynol and panaxytriol isolated from Panax ginseng C. A. Meyer. DNA synthesis of L1210 cells was significantly inhibited with dose dependent pattern when L1210 cells were treated for 1 hour with over 5 .mu.g/ml of polyacetylenes. Panaxydol which had the most potent cytotoxicity among three polyacetylenes showed also the strongest inhibitory effect on DNA synthesis. Intracellular cyclic AMP levels of L1210 cells treated with 2.5 $\mu$g/ml of panaxydol or panaxytriol were significantly elevated on the incubation duration. The elevation of cyclic AMP levels by panaxytriol was higher than that by panaxydol, but no significant increase in cyclic AMP by panaxynol was observed. All three polyacetylenes had no effect on glycolysis of L1210 cells. Electron microscopic observations revealed that polyacetylenes caused damage to plasma membranes of L1210 cells in proportion to their cytotoxicities at each $ED_{50}$ value (panaxydol > panaxynol> panaxytriol). These results suggest that cytotoxicities of polyacetylenes against L1210 cells might be mediated by elevated cyclic AMP level, even though the relationship among their cytotoxicities, inhibitory effect on DNA synthesis and ability to elevation of cyclic AMP level are not fully agreed, and might be also related to membrane damage.

• Carbon letters
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• 제16권4호
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• pp.233-240
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• 2015

Electrochemical synthesis was employed to prepare a novel hydroxyapatite/graphene (HAP/Gr) composite powder suitable for medical applications as a hard tissue implant (scaffold). The synthesis was performed in a homogeneous dispersion containing Na₂H₂EDTA·2H₂O, NaH₂PO₄ and CaCl₂ with a Ca/EDTA/PO₄³⁻ concentration ratio of 0.25/0.25/0.15M, along with 0.01 wt% added graphene nanosheets, at a current density of 137 mA cm⁻² and pH value of 9.0. The field emission scanning electron microscopy and transmission electron microscopy observations of the composite HAP/Gr powder indicated that nanosized hydroxyapatite particles were uniformly placed in the graphene overlay. Raman spectroscopy, Fourier transform infrared spectroscopy and X-ray diffraction confirmed graphene incorporation in the HAP/Gr powder. The electrochemically prepared HAP/Gr composite powder exhibited slight antibacterial effect against the growth of the bacterial strain Staphylococcus aureus.

• 환경위생공학
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• 제13권1호
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• pp.44-56
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• 1998

This study was performed to investigate the reaction characteristics of piggery wastewater for biological nutrient removal. The reaction characteristics were discussed the fraction of organics, the behavior of nitrogen, nitrification, denitrification, and the behavior of phosphorus. The fraction of readily biodegradable soluble COD was 11-12 percent. The ammonia nitrogen was removed via stripping, nitrification, autotrophic cell synthesis, and heterotrophic cell synthesis. The removal percents by each step were 12.1%, 68.9%, 15.0%, and 4.0%, respectively. Nitrification inhibition of piggery wastewater was found to occur at an influent volumetric loading rate over 0.2 NH$_{3}$-N kg/m$^{3}$/d. Denitrification rates were the highest in the raw wastewater and the lowest in the anaerobic effluent. The denitritation of piggery wastewater came out to be possible, and the rate of organic carbon consumption decreased about 10 percent. The phosphorus removed was released in the form of ortho-p in the aerobic fixed biofilm reactor, it was caused by autooxidation. The synthesis and release of phosphorus were related to the ORP and the boundary value for the phase change was about 170mV. In the synthesis phase, the phosphorus removal rate per COD removed was 0.023mgP$_{syn}$/mgCOD$_{rem}$. The phosphorus contents of the microorganism were 4.3-6.0% on a dry weight basis.

• 대한화학회지
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• 제57권6호
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• pp.769-777
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• 2013

The effect of operating conditions (temperature and the partial pressures of H2 and CO) on the reaction rate of Fischer-Tropsch synthesis (FTS) were investigated by carrying out experiments according to a Box-Behnken design (BBD), and were mathematically modeled by using response surface methodology (RSM). The catalyst used was a nano-structured cobalt/manganese oxide catalyst, which was prepared by thermal decomposition. The rate of synthesis was measured in a fixed-bed micro reactor with $H_2/CO$ molar feed ratio of 0.32-3.11 and reactor pressure in the range of 3-9.33 bar at space velocity of $3600h^{-1}$ and a temperature range of 463.15-503.15 K, under differential conditions (CO conversion below 2%). The results indicated that in the present experimental setup, the temperature and the partial pressure of CO were the most significant variables affecting reaction rate. Based on statistical analysis the quadratic model of reaction rate of FTS was highly significant as p-value 0.0002.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2000년도 추계종합학술대회 논문집(2)
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• pp.329-332
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• 2000

This paper proposed resource allocation algorithm for the minimum power consumption of functional unit in high level synthesis process as like DSP which is circuit to give many functional unit. In this paper, the proposed method though high level simulation find switching activity in circuit each functional unit exchange for binary sequence length and value bit are logic one value. To used the switching activity find the allocation with minimal power consumption, the proposed method visits all control steps one by one and determines the allocation with minimal power consumption at each control step.

• 환경영향평가
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• 제25권2호
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• pp.141-154
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• 2016

본 연구는 자연환경이 우리의 사회 경제에 기여하는 진정한 가치를 평가하기 위한 노력들 중의 하나인 에머지(Emergy) 개념을 이용하여 국토의 실질적인 생태학적 가치와 사회 경제적 시스템간 상호작용을 규명하고, 국토의 지속성이 어느 정도 단계에 있는가를 평가하여 이를 바탕으로 국토환경용량을 산정하는데 주안점을 두고 시도되었다. 특히 인구에 회자되고 있는 환경용량을 고려한 지속가능한 개발이라는 개념이 논자의 주관에 따라 달리 평가되면서 이러한 지속가능성을 분석해 볼 수 있는 분석적인 틀(framework)이 잘 정비되어 있지 못함과 지속가능한 개발 또는 발전의 기본이 되는 인간과 자연간의 상호작용에 대한 보다 깊은 분석과 평가를 요구하는 현실을 주목하였다. 그리하여 환경용량을 고려한 지속 가능한 발전이 지니는 함의를 토대로 환경과 경제를 통합하여 분석이 가능한 에머지 개념을 이용하여 국토의 지속가능한 개발이 가능한가를 평가하고 우리 국토에 알맞은 환경용량과 지수를 산정하여 국토의 올바른 개발 방향을 모색하고, 이를 통해 국토이용계획의 정책결정에 있어 지속가능한 국토의 이용 및 관리를 유도할 수 있는 정책을 마련하는데 그 기틀을 제공하고자 함을 목적으로 하였다.

• Asian-Australasian Journal of Animal Sciences
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• 제18권3호
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• pp.326-331
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• 2005

A rumen simulated continuous culture (RSCC) system was used to study the influence of supplementation of the three different types of protein sources such as urea, casein and soy protein on rumen microbial synthesis in terms of rumen microbial synchronization. The urea treatment showed the highest pH value. Ammonia nitrogen concentration was rapidly increased after feeding and not significantly different in the urea treatment (13.53 mg/100 ml). Protozoa numbers were not significantly different for soy protein and casein treatment compared to urea treatments during incubation. The average concentration of total VFA (mMol) was not detected with significant difference among treatments, but iso-butyrate production showed the highest for soy protein treatment among treatments (p<0.001). The lowest concentration in total iso-acids (iso-butyrate and iso-valerate) production was observed in urea treatment. The soy protein treatment showed no significantly change in acetate/propionate. The amounts of dry matter (DM) out flow showed no significant difference among treatments. Organic matter (OM) flow was the highest for urea treatments and the lowest for casein treatment (p<0.03). The nitrogen flow for casein treatment was not significantly different from other treatments. The efficiency of microbial protein synthesis in terms of microbial nitrogen (MN) synthesis (g MN/kg ADOM) digested in the rumen was highest for casein treatment (58.53 g MN/kg ADOM) compared to soy protein and urea (p<0.05). This result suggests that rumen ammonia releasing rate may influence on microbial protein synthesis in the rumen.

• 한국ITS학회 논문지
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• 제17권5호
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• pp.77-87
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• 2018

교통밀도는 교통수요와 가장 직접적인 관계가 있으므로 거시적인 지표 중에서 가장 중요하다고 알려져 있으며(Traffic Engineering, 2004), 특정시각 주어진 거리 안의 존재하는 차량의 대수로 정의한다. 하지만, 밀도는 기상과 도로조건 및 비용 상의 문제로 인하여 현장에서 직접 수집이 어렵다. 이런 이유로 속도와 교통량보다 상대적으로 연구가 활발하게 이루어지지는 않아 수집방법에 관한 다양한 시도뿐만 아니라 측정된 값의 정확도에 관한 연구가 많이 부족하다. 이에 본 논문에서는 밀도를 측정할 수 있는 방법으로 여러 대의 카메라 영상을 정합(synthesis)하는 기술을 활용하였다. 이러한 밀도수집시스템으로 수집한 밀도를 정의에 기반한 참값으로 선정하고, 이 값을 전통적인 측정방법들로 산출한 밀도와 비교하였다. 비교결과, 관계식(fundamental equation)을 이용한 산출방법으로 산출한 밀도 값이 참값과 비교하여 RMSE(Root Mean Square Error)가 1.8-2.5로 가장 참값에 가깝다. 또한 향후 밀도를 직접 수집할 때 유의하여할 수집 간격 등의 간과하기 쉬운 이슈사항을 순간밀도와 평균밀도를 산출하여 알아보았다. 실험 사이트의 실제 교통상황은 LOS B임에도 불구하고, 초 당 순간밀도는 최대(16veh/km)에서 최소 2(veh/km)의 값이 다양하게 관측되어 교통상황의 판단이 어려웠다. 하지만 30초 간격으로 15분 평균밀도는 8.3-7.9(veh/km)로 정확하게 LOS B를 판단하였다.

• 한국전기전자재료학회논문지
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• 제29권9호
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• pp.552-558
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• 2016

Goethite, ${\alpha}$-FeOOH have various applications such as absorbent, pigment and source for magnetic materials. Goethite particles were synthesized in a two step process, where $Fe(OH)_2$ were synthesized in nitrogen atmosphere using $FeSO_4$ as a raw material in the first process, and after that acicular goethite particles were obtained in an air oxidation process of $Fe(OH)_2$ in highly alkaline aqueous solution. Their phase and microstructure were investigated with XRD and FE-SEM. It was found that the morphology of goethite and the ratio of length-to-width (aspect ratio) of acicular goethite are dependent on the some factors such as R value ($OH^-/Fe^{2+}$), air flow rate and pH conditions. In particular, R value has the strongest influence on the synthesized goethite morphology. It is considered that the optimal value R is 4.5 because X-ray diffraction peaks of goethite have the highest intensity at that value. Morphology of goethite particles was controlled by air flow rates, showing that their size and aspect ratio are getting smaller and decrease, respectively as air flow rate increases. The largest goethite particle obtained is about 1,500 nm in length and 150 nm in diameter.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2003년도 학술회의 논문집 정보 및 제어부문 B
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• pp.946-949
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• 2003

In this paper, a DDFS(Direct Digital Frequency Synthesis)chip has been designed focusing on the reduction of ROM size and implemented using FPGA. When calculating the sine value for the input phase value, we used the Taylor series expansion approximation method to reduce the number of addresses of ROM. We also used the piecewise straight line approximation method, ie, the stored value int the ROM is the difference of the sine value and the straight line approximation. Using this method, we could reduce four bits for each ROM data.