• Title/Summary/Keyword: Synthesis optimization

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Reaction Optimization for Enzymatic Synthesis of Astragalin (효소를 이용한 아스트라갈린 합성 반응의 최적화)

  • Lee, Seul Bi;Chung, Dae-won
    • Applied Chemistry for Engineering
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    • v.23 no.4
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    • pp.394-398
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    • 2012
  • Astragalin (AS), kaempferol monoglycoside, is classified as a polyphenol, and a minute quantity of AS is known to be present in several plants. Recently, it was reported that AS can be prepared by the partial hydrolysis of camelliaside A (CamA) and camelliaside B (CamB) in the tea seed extract (TSE) in the presence of a commercial enzyme complex such as Mash. In this paper, the effects of reaction temperature, amount of enzyme, and the substrate concentration on the reactivity were investigated. As the reaction temperature or the amount of enzyme increased, the reaction rate to produce AS increased, however, the hydrolysis of AS into KR was also enhanced. As a conclusion, the reaction, when 2 mL of Mash to 1 g of TSE was applied with a substrate concentration of 15% at $50^{\circ}C$, was found to be optimum, based on the reaction rate and the selectivity to AS.

Synthesis of Single Crystal Diamond by Variation of Deposition Pressure by HFCVD (HFCVD에 의한 증착압력 변화에 따른 Single Crystal Diamond 합성)

  • Kim, Min Su;Bae, Mun Ki;Kim, Seong-Woo;Kim, Tae Gyu
    • Journal of the Korean Society for Heat Treatment
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    • v.33 no.1
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    • pp.20-24
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    • 2020
  • Single crystal diamonds are in great demand in such fields as mechanical, electronic applications and optoelectronics. Large area single crystal diamonds are attracting attention in future industries for mass production and low cost. In this study, hot filament CVD (HFCVD) is used to grow large area single crystal diamond. However, the growth rate of large area single crystal diamond using HFCVD is known to be very low. The goal of this study is to use single crystal diamond substrates in HFCVD with methane-hydrogen gas mixtures to increase the growth rate of single crystal diamond and to optimize the conditions by analysing the effects of deposition conditions for high quality crystallinity. The deposition pressure, the ratio of CH4/H2 gas, the substrate temperature and the distance between the filament and the substrate were optimized. The sample used a 4×4 (mm2) size single crystal diamond substrate (100), the CH4/H2 gas ratio was fixed at 5%, the substrate temperature was synthesized to about 1000℃. At this time, the deposition pressure was changed to three types of 50, 75, 85 Torr and deposited. Finally, optimization was investigated under pressure conditions to analyse the growth rate and quality of single crystal diamond.

Generating Augmented Lifting Player using Pose Tracking

  • Choi, Jong-In;Kim, Jong-Hyun
    • Journal of the Korea Society of Computer and Information
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    • v.25 no.5
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    • pp.19-26
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    • 2020
  • This paper proposes a framework for creating acrobatic scenes such as soccer ball lifting using various users' videos. The proposed method can generate a desired result within a few seconds using a general video of user recorded with a mobile phone. The framework of this paper is largely divided into three parts. The first is to analyze the posture by receiving the user's video. To do this, the user can calculate the pose of the user by analyzing the video using a deep learning technique, and track the movement of a selected body part. The second is to analyze the movement trajectory of the selected body part and calculate the location and time of hitting the object. Finally, the trajectory of the object is generated using the analyzed hitting information. Then, a natural object lifting scenes synchronized with the input user's video can be generated. Physical-based optimization was used to generate a realistic moving object. Using the method of this paper, we can produce various augmented reality applications.

Development of non-fragile $H_{\infty}$ controller design algorithm for singular systems (특이시스템의 비약성 $H_{\infty}$ 제어기 설계 알고리듬 개발)

  • Kim, Jong-Hae
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.42 no.6
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    • pp.9-14
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    • 2005
  • In this paper, we consider the synthesis of non-fragile $H_{\infty}$ state feedback controllers for singular systems and static state feedback controller with multiplicative uncertainty. The sufficient condition of controller existence, the design method of non-fragile $H_{\infty}$ controller, and the measure of non-fragility in controller are presented via LMI(linear matrix inequality) technique. Also, the sufficient condition can be rewritten as LMI form in terms of transformed variables through singular value decomposition, some changes of variables, and Schur complements. Therefore, the obtained non-fragile $H_{\infty}$ controller guarantees the asymptotic stability and disturbance attenuation of the closed loop singular systems within a prescribed degree. Moreover, the controller design method can be extended to the problem of robust and non-fragile $H_{\infty}$ controller design method for singular systems with parameter uncertainties. Finally, a numerical example is given to illustrate the design method.

Design of a Waveguide Broad-wall Longitudinal Slot Array Antenna of X-type Monopulse Axes (X-형 모노펄스 축구조를 가지는 도파관 광벽 종방향 슬롯 배열 안테나의 설계)

  • 나형기;박창현
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.13 no.2
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    • pp.208-216
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    • 2002
  • In this paper, the design method of a waveguide broad-wall longitudinal slot array monopulse antenna of X-type monopulse axes is presented, and the method is verified through manufacture and measurement. In the antenna design of this paper, the antenna size is small and the monopulse axes are X-type. Thus, the common continuous aperture distribution fuction is not suitable and the power balance among antenna quadrants should be considered. Also, since the waveguide height is reduced into 0.1 wavelength, the modelling of the slot characteristics is not simple. Thus, in this paper, the aperture distribution is optimized by using random number, and the balance among the quadrants is achieved by applying the quadrant weighting factor during the aperture optimization process. Also, the moment method procedure is accelerated by applying the interpolation technique to some part of the moment matrix, and the moment method procedure is added to the array synthesis program as a subroutine so that the slot characteristics can be calculated directly when it is required. Based on this method, a antenna of 28dBi is designed and manufactured. It is found that the antenna characteristics is similar to design data.

Optimization of $Nd^{3+}$ ion co-doping in $CaAl_2O_4:\;Eu^{2+}$ blue phosphor ($CaAl_2O_4:Eu^{2+}$ 청색(靑色) 형광체(螢光體)의 $Nd^{3+}$ 도핑 최적화(最適化)에 관한 연구(硏究))

  • Bartwal, Kunwar Singh;Ryu, Ho-Jin
    • Resources Recycling
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    • v.16 no.5
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    • pp.46-50
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    • 2007
  • Blue phosphor calcium aluminate, $CaAl_2O_4:Eu^{2+}$ co-doped with $Nd^{3+}$ was prepared by solid state synthesis method. Phosphor materials with 1 mol% $Eu^{2+}$ and varying compositions of $Nd^{3+}$ show high brightness and long persistent luminescence. The synthesized phosphor materials were investigated by powder x-ray diffraction (XRD), SEM, TEM, photoluminescence excitation and emission studies. Broad band UV excited luminescence of the $CaAl_2O_4:Eu^{2+}:Nd^{3+}$ was observed in the blue region (${\lambda}_{max}=440\;nm$) due to transitions from the $4f^65d^1$ to the $4f^7$ configuration of the $Eu^{2+}$ ion. $Nd^{3+}$ ion doping in the phosphor results in long afterglow phosphorescence when the excitation light is cut off.

Optimization of Silver Nanoparticles Synthesis through Design-of-Experiment Method (실험계획법을 활용한 은 나노 입자의 합성 및 최적화)

  • Lim, Jae Hong;Kang, Kyung Yeon;Im, Badro;Lee, Jae Sung
    • Korean Chemical Engineering Research
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    • v.46 no.4
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    • pp.756-763
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    • 2008
  • The aim of this work was to obtain uniform and well-dispersed spherical silver nanoparticles using statistical design-of-experiment methods. We performed the experiments using 2 k fractional factorial designs with respect to key factors of a general chemical reduction method. The nanoparticles prepared were characterized by SEM, TEM and UV-visible absorbance for particle size, distribution, aggregation and anisotropy. The data obtained were analyzed and optimized using a statistical software, Minitab. The design-of-experiment methods using quantified data enabled us to determine key factors and appreciate interactions between factors. The measured properties of nanoparticles were dominated not only by individual one or two main factors but also by interactions between factors. The appropriate combination of the factors produced small, narrow-distributed and non-aggregated silver nanoparticles of about 30 nm with approximately 10% standard deviation.

A Study on the Reaction Optimization for the Utilization of CO2 and CH4 from Bio-gas (바이오가스에서 CO2/CH4 활용에 관한 반응최적화 연구)

  • KHO, DONGHYUN;CHO, WOOKSANG;BAEK, YOUNGSOON
    • Transactions of the Korean hydrogen and new energy society
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    • v.27 no.5
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    • pp.554-561
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    • 2016
  • Depending on the Bio-gas sources, main component gases of $CH_4$ and $CO_2$ are shown to be variously present in amounts. For the anaerobic digester, The concentration of $CH_4$ and $CO_2$ in the gases are 60~70 and 30~35 vol%. For the landfill gas, $CH_4$ and $CO_2$ are 40~60 and 40~60 vol%. For the food wastes, $CH_4$ and $CO_2$ are 60~80 and 20~40 vol%, respectively. In this study, maximum conversion rates of $CO_2$ were obtained from the variety of concentrations of $CH_4$ and $CO_2$ by the catalysts of reforming reactions. Moreover, in order to get maximum producing amount of synthetic gas, experimental studies were performed to optimize the reaction variables. On the basis of $CH_4$, 243 ml, R [$CH_4/(O2+CO_2)$] value were varied from 0.8 to 1.35, in the study of $CH_4$ and $CO_2$ reforming reactions. It was shown that the optimal results were obtained for 1.35 of R value. And also, at $850^{\circ}C$ and 1 atm, the production rate of synthetic gas was 90% and the conversion rates of $CH_4$ and $CO_2$ were higher than 99% and 90%, respectively.

Window Approach for Cosine-Modulated Filter Bank Design for Multitone Data Communication (윈도우를 이용한 멀티톤 데이터 통신용 코사인 변조 필터뱅크 디자인)

  • 김정학;신승철;정진균;송상섭
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.24 no.8B
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    • pp.1586-1592
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    • 1999
  • In DWMT, CMFB is employed in the synthesis/analysis part. The CMFB uses filters of greater length than the DFT, resulting in reduced interference between the carriers. In addition, the CMFB system is computationally efficient and fast algorithms are available for their implementation. Traditional designs for the prototype filters of CMFB usually involve nonlinear optimizations. Thus the required design time is considerably large even for small filter orders. In this paper, a prototype filter design method for CMFB is presented using optimal window method. The design process is reduced to the optimization of a single parameter and consequently the required design time is much less than those of the existing methods. It is shown that the stopband performance of the proposed method is better than that of the Kaiser window method.

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Optimization of Culture Medium for Novel Cell-Associated Tannase Production from Bacillus massiliensis Using Response Surface Methodology

  • Belur, Prasanna D.;Goud, Rakesh;Goudar, Dinesh C.
    • Journal of Microbiology and Biotechnology
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    • v.22 no.2
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    • pp.199-206
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    • 2012
  • Naturally immobilized tannase (tannin acyl hydrolase, E.C. 3.1.1.20) has many advantages, as it avoids the expensive and laborious operation of isolation, purification, and immobilization, plus it is highly stable in adverse pH and temperature. However, in the case of cell-associated enzymes, since the enzyme is associated with the biomass, separation of the pure biomass is necessary. However, tannic acid, a known inducer of tannase, forms insoluble complexes with media proteins, making it difficult to separate pure biomass. Therefore, this study optimizes the production of cell-associated tannase using a "protein-tannin complex" free media. An exploratory study was first conducted in shake-flasks to select the inducer, carbon source, and nitrogen sources. As a result it was found that gallic acid induces tannase synthesis, a tryptose broth gives higher biomass, and lactose supplementation is beneficial. The medium was then optimized using response surface methodology based on the full factorial central composite design in a 3 l bioreactor. A $2^3$ factorial design augmented by 7 axial points (${\alpha}$ = 1.682) and 2 replicates at the center point was implemented in 17 experiments. A mathematical model was also developed to show the effect of each medium component and their interactions on the production of cell-associated tannase. The validity of the proposed model was verified, and the optimized medium was shown to produce maximum cell-associated tannase activity of 9.65 U/l, which is 93.8% higher than the activity in the basal medium, after 12 h at pH 5.0, $30^{\circ}C$. The optimum medium consists of 38 g/l lactose, 50 g/l tryptose, and 2.8 g/l gallic acid.