• The Journal of the Acoustical Society of Korea
• /
• v.22 no.6
• /
• pp.425-433
• /
• 2003

Acoustic Echo Canceller (AEC) is a signal processing system for removing unwanted echo signals in teleconference and hands-free communication. Least mean square (LMS) algorithm is one of the adaptive echo cancellation algorithms and it has been most attractive because of its simplicity and robustness. However, the convergence properties of the LMS algorithm degrade with highly correlated input signals such as speech. For this reason, transform-domain adaptive filtering algorithm was introduced to decorrelate the colored input samples by using the orthogonal transform matrix such as DCT, DFT and then LMS adaptive filtering process is applied. In this paper, we propose a MLT domain adaptive echo canceller base on the MLT (Modulated lapped Transform) orthogonal transform matrix. The proposed algorithm achieves high decorrelation efficiency and fast convergence speed via modulated lapped transform of size 2NXN instead of NXN unitary transform such as DCT, DFT, Hadamad and it is applied to the acoustical echo cancellation system. Form the computer simulation with both synthesis and real speech, the proposed MLT domain adaptive echo canceller shows approximately twice faster convergence speed and 20∼30 ㏈ ERLE improvements over the DCT frequency domain acoustic echo cancellation system.

• Research in Plant Disease
• /
• v.12 no.1
• /
• pp.40-45
• /
• 2006

The plant defence activator, Acibenzolar-S-methyl [benzo (1,2,3) thiadiazole-7-carbothioic acid-S-methyl ester, ASM] was assayed on tomato seedlings for its ability to induce resistance against Botrytis cinerea, the causal agent of gray mold in tomato. Pre-treatment of plants with ASM reduced the severity of the disease as well as the growth of the mycelium in plants. In ASM treated plants, reduction in disease severity (up to 55%) was correlated with suppression of mycelia growth (up to 46.5%) during the time course of infection. In plants treated with ASM, activities of peroxidase were determined as markers of resistance. Applications of ASM induced Progressive and significant increase of the enzyme in locally treated tissues. Such responses were expressed earlier and with a much higher magnitude when ASM-treated seedlings were challenged with the pathogen, thus providing support to the concept that a signal produced by the pathogen is essential for triggering enhanced synthesis and accumulation of the enzymes. No such activities were observed in water-treated control plants. Therefore, the slower symptom development and reduction in mycelium growth in ASM treated plants might be due to the increase in activity of oxidative and antioxidative protection systems in plants.

• Journal of The Korean Society of Grassland and Forage Science
• /
• v.25 no.4
• /
• pp.287-296
• /
• 2005

To investigation protein expression pattern in rice leaves exposed to cold stress, the soluble proteins extracted from leaf tissue were fractionated with $15\%$ PEG and separated by two-dimensional polyacrylamide gel electrophoresis (2-DE). Differentially expressed proteins were identified by peptide mass fingerprinting using matrix assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS). Eight proteins up-regulated and 10 down-regulated were found in $15\%$ PEG supernatant fraction. In addition, 13 proteins up-regulated and 14 down-regulated were found in $15\%$ PEG pellet fraction. It was identified the differentially expressed proteins in $15\%$ PEG supernatant fraction as pimerase/dehydratase fructokinase, ribose-5-phosphate isomerase (Rpi), chaperonin 21 precursor, probable photosystem II oxygen-envolving complex (PS II OEC) protein 2 precursor and thioredoxin h-type (Trx-h) and those in $15\%$ PEG pellet fraction as OSINBb0059K02.15, hypothetical protein, putative mitogen-activated protein kinase kinase (MAPKK), beta 7 subunit of 205 proteasome, ribulose-1, 5-bisphosphate carboxylase/oxygenase (Rubisco) small subunit. These proteins are involved in metabolism, energy, protein synthesis, disease/defense and signal transduction-related proteins.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.36 no.6C
• /
• pp.349-354
• /
• 2011

Passive millimeter wave imaging has the capability of detecting concealed objects under clothing. Also, passive millimeter imaging can obtain interpretable images under low visibility conditions like rain, fog, smoke, and dust. However, the image quality is often degraded due to low spatial resolution, low signal level, and low temperature resolution. This paper addresses image registration and fusion between passive millimeter images and visual images. The goal of this study is to combine and visualize two different types of information together: human subject's identity and concealed objects. The image registration process is composed of body boundary detection and an affine transform maximizing cross-correlation coefficients of two edge images. The image fusion process comprises three stages: discrete wavelet transform for image decomposition, a fusion rule for merging the coefficients, and the inverse transform for image synthesis. In the experiments, various types of metallic and non-metallic objects such as a knife, gel or liquid type beauty aids and a phone are detected by passive millimeter wave imaging. The registration and fusion process can visualize the meaningful information from two different types of sensors.

• Korean Journal of Veterinary Research
• /
• v.38 no.1
• /
• pp.29-42
• /
• 1998

$Mg^{2+}$ is one of the most abundant divalent cations in mammalian body(0.2~1.0mM) and the important physiological roles are : first, the cofactor of many enzyme activities, second, the regulator of glycolysis and DNA synthesis, third, the important role of bioenergetics by regulating of phosphorylation, fourth, the influence of cardiac metabolism and function. In this work we have investigated the regulation of the $Mg^{2+}$ induced by ${\alpha}_1-adrenoceptor$ stimulation in perfused guinea pig hearts and isolated myocytes. The $Mg^{2+}$ content of the perfusate or the supernatant was measured by atomic absorbance spectrophotometry. The elimination of $Mg^{2+}$ in the medium increased the force of contraction of right ventricular papillary muscles, and the left ventricular pressure. Phenylephrine also enhanced the force of contraction in the presence of $Mg^{2+}-free$ medium. ${\alpha}_1-Agonists$ such as phenylephrine and methoxamine were found to induce $Mg^{2+}$ efflux in both perfused hearts and myocytes. These effects were blocked by prazosin, an ${\alpha}_1-adrenoceptor$ antagonist. The $Mg^{2+}$ influx could also be induced by phenylephrine and R59022, a diacylglycerol kinase inhibitor. In the presence of protein kinase C(PKC) inhibitors, phenylephrine produced an increase in $Mg^{2+}$ efflux from perfused hearts. Furthermore, $Mg^{2+}$ efflux by phenylephrine was amplified by phorbol 12-myristate 13-acetate(PMA). This enhancement of $Mg^{2+}$ efflux by PMA was blocked by prazosin in perfused hearts. By contrast, the $Mg^{2+}$ influx could be induced by verapamil, nifedipine, ryanodine in perfused hearts, but not in myocytes. $W^7$, a $Ca^{2+}$/calmodulin antagonist, completely blocked the phenylephrine-induced $Mg^{2+}$ efflux in perfused hearts. In conclusion, $Mg^{2+}$ is responsible for the cardiac activity associated with ${\alpha}_1-adrenoceptor$ stimulation. The mobilization of $Mg^{2+}$ is decreased or increased by ${\alpha}_1-adrenoceptor$ stimulation in guinea pig hearts. These responses may be related specifically to the respective pathways of signal transduction. A decrease in $Mg^{2+}$ efflux by ${\alpha}_1-adrenoceptor$ stimulation in hearts can be through PKC dependent and intracellular $Ca^{2+}$ levels.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.33 no.2
• /
• pp.87-92
• /
• 2007

To develop the skin whitening agent, we investigated the effects of Acanthopeltis japonica, a rhodophyta on the coast of Jeju island, on melanogenesis. Dried A. japonica was refluxed with 70 % aqueous ethanol and the extract was evaporated to dryness. To validate the activity as a depigmenting agent, various in vitro tests, polyphenol contents, and free radical scavenging activity were performed. In addition, cellular tyrosinase activity and protein expression of p-ERT, tyrosinase, TRP-1, and TRP-2 were measured in B16/F10 murine melanoma cells. A. japonica had low polyphenol contents and low free radicals scavenging activities against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. A. japonica suppressed cellular tyrosinase activity up to 86.9 % at $100{\mu}g/mL$ with inhibition or tyrosinase and TRP-1 expression in ${\alpha}$-melanocyte stimulating hormone (${\alpha}$-MSH)-treated B16/F10 melanoma cells. Our results suggest that inhibitory effects of A. japonica on melanogenesis are due to inhibiting the pathways involving ${\alpha}$-MSH-induced ERK activation. Therefore, A. japonica nay be useful as a skin whitening agent associated with the suppressive effect of melanotrophin-induced signaling pathway to inhibit melanin synthesis.

• Journal of Digital Convergence
• /
• v.16 no.10
• /
• pp.351-356
• /
• 2018

Changes in vocal cords due to aging can change the frequency of speech, and the speech signals of the elderly can be automatically distinguished from normal speech signals through various analyzes. The purpose of this study is to provide a tool that can be easily accessed by the elderly and disabled people who can be excluded from the rapidly changing technological society and to improve the voice recognition performance. In the study, the gender of the subjects was reported as sex analysis, and the number of female and male voice samples was used equally. In addition, the gender analysis was applied to set the voices of the elderly without using voices of all ages. Finally, we applied a review methodology of standards and reference models to reduce gender difference. 10 Korean women and 10 men aged 70 to 80 years old are used in this study. Comparing the F0 value extracted directly with the waveform and the F0 extracted with TF32 and the Wavesufer speech analysis program, Wavesufer analyzed the F0 of the elderly voice better than TF32. However, there is a need for a voice analysis program for elderly people. In conclusions, analyzing the voice of the elderly will improve speech recognition and synthesis capabilities of existing smart medical systems.

• The Korean Journal of Zoology
• /
• v.39 no.4
• /
• pp.337-351
• /
• 1996

Melatonin Is a multifunctional hormone secreted from the pineal gland in the middle of cerebrum and cerebellum. Its synthesis and release reflect photopedod;Photopedod is a yearly predictable ambient factor that most animals utilize as an environmental cue for maximum survival. Hamsters maintaln reproductive activity in summer during which day length exceeds night time. Upon the advent of autumnal equinox they undergo gonadal regression. The photoperiodic effects are prevented by removal of the pineal gland and restored by the timed repiacument of melatonin. The results suggest that melatonin constitutes part of control mechanism whereby environmental information is transduced to neuroendocrine signal responsIble for the functional integrity of the reproductive system. From the studies for the action site of melatonin following the treatment of photopedod or melatonin in the lesion of a spedflc portion of hypothalamus, suprachiasmatic nuclei and pars tuberalis are shown to be a consensus site for melatonIn. The action of melatonin. In the regulation of reproduction is largely unknown. It is mainly due to the lack of acute effect of melatonin on gonadotropin secretion. However, reduction of the gonadotropln release and augmentation of the hypothalamic gonadotropin-releasing hormone (GnRH) content by long-term treatment of melatonln Indicate that constant presence of melatonln may partidpate in the regulation of sexual activity via the GnRH neuronal system. The action mechanism by which melatonin exerts Its effect on GnRH neuron needs to be eluddated. The inability of opiold analogues to affect the reproductive hormones in sexually regressed animals by inhibftory photopedod and melatonin suggests that the opioldergic neuron may be a prime intervening mediator. Recent cloning of melatonin receptor will contribute to investigate its anatomical Identification and the action mechanism of melatonin on target tissues at the molecular level.

• Journal of the Korea Society of Computer and Information
• /
• v.15 no.7
• /
• pp.91-98
• /
• 2010

Large corpus-based concatenating Text-to-Speech (TTS) systems can generate natural synthetic speech without additional signal processing. Because the improvements in the natualness, personality, speaking style, emotions of synthetic speech need the increase of the size of speech DB, it is necessary to prune the redundant speech segments in a large speech segment DB. In this paper, we propose a new method to construct a segmental speech DB for the Korean TTS system based on a clustering algorithm to downsize the segmental speech DB. For the performance test, the synthetic speech was generated using the Korean TTS system which consists of the language processing module, prosody processing module, segment selection module, speech concatenation module, and segmental speech DB. And MOS test was executed with the a set of synthetic speech generated with 4 different segmental speech DBs. We constructed 4 different segmental speech DB by combining CM1(or CM2) tree clustering method and full DB (or reduced DB). Experimental results show that the proposed method can reduce the size of speech DB by 23% and get high MOS in the perception test. Therefore the proposed method can be applied to make a small sized TTS.

• Journal of Life Science
• /
• v.18 no.4
• /
• pp.537-541
• /
• 2008

White adipose tissue is now recognized as an important endocrine organ which secretes various signal factors and proteins termed 'adipokine'. Haptoglobin (Hp), which has been known as an acute phase protein, belongs to the adipokine. However, the function of Hp in adipose tissue remains unclear. To verify the role of Hp in preadipocytes, in this study, 3T3-L1 preadipocyte cells were stably transfected with human Hp gene and Hp-overexpressing cells were made. The Hp had no effect on cell growth of preadipocytes. By RT-PCR and Western blot analysis, the Hp inhibited gene expression of IL-6 and COX-2 and enhanced HO-1 synthesis in preadipocytes. Moreover, invasion assay showed the Hp suppressed migration of monocytes to preadipocytes. These findings suggest that the Hp may inhibit an inflammatory reaction in adipose tissue by regulating the expressions of pro-inflammatory and anti-inflammatory mediators, and by repressing monocytes/macrophages infiltration.