• 제목, 요약, 키워드: Synthesis

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Efficient Synthesis of An Epoxy Alcohol, A key Intermediate for$LTA_4$ Synthesis

  • Hokoon Park;Yong Sup Lee;Sang Chul Shim
    • Bulletin of the Korean Chemical Society
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    • v.13 no.5
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    • pp.551-553
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    • 1992
  • An efficient and very short synthesis of epoxy alcohol 5, a key intermediate for leukotriene synthesis, was described. The key reaction involves the regioselective benzylidene acetal formation from methyl 5,6,7-trihydroxyheptanoate 1.

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Melandrin의 합성 (Synthesis of Melandrin)

  • 문정술;이강노;임중기;우원식
    • 약학회지
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    • v.35 no.4
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    • pp.332-334
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    • 1991
  • The synthesis of melandrin has been accomplished in good yield by the reaction of 5-tosyloxyanthranilic acid ethyl ester with p-acetoxybenzoyl chloride, followed by removal of protecting groups with methanolic ammonia.

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SYNTHESIS OF NANO-SIZED IRON FOR REDUCTIVE DECHLORINATION. 2. Effects of Synthesis Conditions on Iron Reactivities

  • Song, Ho-Cheol;Carraway, Elizabeth R.;Kim, Young-Hun
    • Environmental Engineering Research
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    • v.10 no.4
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    • pp.174-180
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    • 2005
  • Nano-sized iron was synthesized using borohydride reduction of $Fe^{3+}$ in aqueous solution. A wide range of synthesis conditions including varying concentrations of reagents, reagent feeding rate, and solution pH was applied in an aqueous system under anaerobic condition. The reactivity of nano-sized iron from each synthesis was evaluated by reacting the iron with TCE in batch systems. Evidence obtained from this study suggest the reactivity of iron is strongly dependent on the synthesis solution pH. The iron reactivity increased as solution pH decreased. More rapid TCE reduction was observed for iron samples synthesized from higher initial $Fe^{3+}$ concentration, which resulted in lower solution pH during the synthesis reaction. Faster feeding of $BH_4^-$ solution to the $Fe^{3+}$ solution resulted in lower synthesis solution pH and the resultant iron samples gave higher TCE reduction rate. Lowering the pH of the solution after completion of the synthesis reaction significantly increased reactivity of iron. It is presumed that the increase in the reactivity of iron synthesized at lower pH is due to less precipitation of iron (hydr)oxides or less surface passivation of iron.