• Title/Summary/Keyword: Synthesis

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The μ-synthesis and analysis of water level control in steam generators

  • Salehi, Ahmad;Kazemi, Mohammad Hosein;Safarzadeh, Omid
    • Nuclear Engineering and Technology
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    • v.51 no.1
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    • pp.163-169
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    • 2019
  • The robust controller synthesis and analysis of the water level process in the U-tube system generator (UTSG) is addressed in this paper. The parameter uncertainties of the steam generator (SG) are modeled as multiplicative perturbations which are normalized by designing suitable weighting functions. The relative errors of the nominal SG model with respect to the other operating power level models are employed to specify the weighting functions for normalizing the plant uncertainties. Then, a robust controller is designed based on ${\mu}$-synthesis and D-K iteration, and its stability robustness is verified over the whole range of power operations. A gain-scheduled controller with $H_{\infty}$-synthesis is also designed to compare its robustness with the proposed controller. The stability analysis is accomplished and compared with the previous QFT design. The ${\mu}$-analysis of the system shows that the proposed controller has a favorable stability robustness for the whole range of operating power conditions. The proposed controller response is simulated against the power level deviation in start-up and shutdown stages and compared with the other concerning controllers.

Array pattern synthesis using semidefinite programming and a bisection method

  • Lee, Jong-Ho;Choi, Jeongsik;Lee, Woong-Hee;Song, Jiho
    • ETRI Journal
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    • v.41 no.5
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    • pp.619-625
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    • 2019
  • In this paper, we propose an array pattern synthesis scheme using semidefinite programming (SDP) under array excitation power constraints. When an array pattern synthesis problem is formulated as an SDP problem, it is known that an additional rank-one constraint is generated inevitably and relaxed via semidefinite relaxation. If the solution to the relaxed SDP problem is not of rank one, then conventional SDP-based array pattern synthesis approaches fail to obtain optimal solutions because the additional rank-one constraint is not handled appropriately. To overcome this drawback, we adopted a bisection technique combined with a penalty function method. Numerical applications are presented to demonstrate the validity of the proposed scheme.

Potential for Efficient Synthesis of GSH Utilizing GCS1 and GLR1 Mutant Strains of Candida albicans

  • Jaeyoung SON;Min-Kyu KWAK
    • The Korean Journal of Food & Health Convergence
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    • v.10 no.2
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    • pp.7-11
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    • 2024
  • Glutathione (GSH) is a vital compound composed of glutamic acid, cysteine, and glycine, crucial for cellular functions including oxidative stress defense and detoxification. It has widespread applications in pharmaceuticals, cosmetics, and food industries due to its antioxidant properties and immune system support. Two primary methods for GSH synthesis are enzymatic and microbial fermentation. Enzymatic synthesis is efficient but costly, while microbial fermentation, particularly using yeast strains like Candida albicans, offers a cost-effective alternative. This study focuses on genetically modifying C. albicans mutants, specifically targeting glutathione reductase (GLR1) and gamma-glutamylcysteine synthetase (GCS1) genes, integral to GSH synthesis. By optimizing these mutants, the research aims to develop a model for efficient GSH production, potentially expanding its applications in the food industry.

GTL(Gas-to-Liquid) 기술 현황

  • Jun, Gi-Won
    • Journal of Energy Engineering
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    • v.16 no.2
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    • pp.58-63
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    • 2007
  • In recent years, the technologies for the production of synthetic fuel from natural gas have been attracting considerable interest because of high oil prices. While oil prices remaining high, GTL (Gas-to-Liquids) technology would provide an attractive option for utilizing gas resources. Furthermore, GTL fuels contain almost zero sulfur and low aromatics and have a very high cetane so that they are estimated to be environmentally friendly diesel fuels able of meeting the advanced fuel specifications of the 21st century. GTL process generally consists of three primary steps: synthesis gas production from natural gas reforming, hydrocarbon production from synthesis gas by Fischer-Tropsch (F-T) synthesis, product upgrading by hydrocracking/hydroisomerization. This paper presents a brief summary of GTL technology and worldwide development trend about it focusing on the reforming of natural gas and the F-T synthesis.

Influence of Refeeding with Vitamin, Mineral and Fibre on Protein Synthesis and Messenger Ribonucleic Acid Content in the Liver and Muscle of Fasted Chicks

  • Aman Yaman, M.;Kita, K.;Pinontoan, R.;Okumura, J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.11 no.5
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    • pp.545-549
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    • 1998
  • The influence of refeeding with either vitamin, mineral, fibre of water on protein synthesis and mRNA content in the liver and breast muscle of fasted chicks was investigated. At 15 d of age, chicks were fasted for 2 d and then refed either vitamin, mineral, fibre or water. The fractional synthesis rate (FSR) of protein was measured after 30 min of refeeding by using a large dose injection of L - 2, $6[^3H]$ phenylalanine. In the liver, FSR was reduced by fasting and tended to increase but not significantly by refeeding with vitamin or mineral. FSR was not affected by refeeding with fibre or water. There was no influence of fasting and refeeding on ribosomal capacity (the RNA : protein ratio) and ribosomal efficiency (total protein synthesised per total RNA). The absolute synthesis rate (ASR) of liver protein and hepatic mRNA content were reduced by fasting and unchanged by refeeding. In the muscle, FSR, ASR and mRNA content were significantly decreased by fasting and not recovered by refeeding with either vitamin, mineral, fibre or water. It concluded that vitamin, mineral, fibre and water have little capacity to stimulate liver and muscle protein synthesis reduced by fasting.

The Fabrication of Cobalt Nanopowder by Sonochemical Polyol Synthesis of Cobalt Hydroxide and Magnetic Separation Method (수산화코발트의 초음파 폴리올 합성과 자성 선별법을 이용한 코발트 나노 분말의 제조)

  • Byun, Jong Min;Choi, Myoung Hwan;Shim, Chang Min;Kim, Ji Young;Kim, Young Do
    • Journal of Powder Materials
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    • v.22 no.1
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    • pp.39-45
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    • 2015
  • In this study, cobalt nanopowder is fabricated by sonochemical polyol synthesis and magnetic separation method. First, sonochemical polyol synthesis is carried out at $220^{\circ}C$ for up to 120 minutes in diethylene glycol ($C_4H_{10}O_3$). As a result, when sonochemical polyol synthesis is performed for 50 minutes, most of the cobalt precursor ($Co(OH)_2$) is reduced to spherical cobalt nanopowder of approximately 100 nm. In particular, aggregation and growth of cobalt particles are effectively suppressed as compared to common polyol synthesis. Furthermore, in order to obtain finer cobalt nanopowder, magnetic separation method using magnetic property of cobalt is introduced at an early reduction stage of sonochemical polyol synthesis when cobalt and cobalt precursor coexist. Finally, spherical cobalt nanopowder having an average particle size of 22 nm is successfully separated.

Development of Commercially Viable Method of Conjugated Linoleic Acid Synthesis Using Linoleic Acid Fraction Obtained from Pork By-products

  • Yoon, Sung Yeoul;Lee, Da Young;Kim, On You;Lee, Seung Yun;Hur, Sun Jin
    • Food Science of Animal Resources
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    • v.38 no.4
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    • pp.693-702
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    • 2018
  • The purpose of this study was to develop a commercially viable method for synthesis of conjugated linoleic acid (CLA) using the linoleic acid fraction obtained from six pork by-products (liver, lung, heart, stomach, small intestine, and large intestine). The workflow of CLA synthesis from each by-product was as follows: washing${\rightarrow}$crude fat extraction${\rightarrow}$fractionation into saturated and unsaturated fatty acids${\rightarrow}$repeat unsaturated fatty acid fractionation${\rightarrow}$CLA synthesis. Cis-9, trans-11, and trans-10, cis-12 CLA was synthesized from pork by-products. The yield of CLA synthesis of pork by-products ranged from 1.55 to 11.18 g per 100 g of by-products. The amount of synthesized CLA was the highest in the small intestine and large intestine by-products. Fractionation of pork by-products nearly doubled the yield of CLA. We suggest that commercial fractionation methods could increase the yield of CLA at low cost, reduce waste, and improve the efficiency of by-product utilization.

A Comparative Analysis of Target Strength Estimated Models for Underwater Echo Signal Synthesis (수중 반사신호 합성을 위한 표적강도 예측모델 비교분석)

  • 김부일
    • Journal of the Korea Institute of Military Science and Technology
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    • v.4 no.1
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    • pp.93-103
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    • 2001
  • A reflection signal in an active sonar using a high frequency is mainly formed of a specular reflection from the surface of an object along with several equivalent scatters inside, which are characterized by the spatial distribution of the highlight on the object. This study analyze the existing echo signal synthesis models eq, random distribution model, equivalent interval distribution model & MUTAHID(Modified Underwater TArget by HIlight Distribution) model for simulated target, and compare the characteristics of the reflected signal synthesis results for each model in various conditions. These highlight distribution models can be efficiently applied to the simulated target signals synthesis of various real systems requiring the echo signal synthesis on the underwater target.

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The Effect of Schizonepeta tenuifolia on Osteoblast (형개(荊芥)가 조골세포(造骨細胞)에 미치는 영향(影響))

  • Lee, Joo-Yup;Hwang, Gwi-Seo
    • Journal of Society of Preventive Korean Medicine
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    • v.13 no.3
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    • pp.127-138
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    • 2009
  • Objectives : The author aimed to evaluate the effect of BuOH fraction(ST) from Schizonepeta tenuifolia on osteoblast proliferation in murine calvarial cells. Methods : The osteoblast separated from murine calvariae was cultivated for 10 days and evaluated the cell function. After the addition of ST on the culture medium, we determined the effect of ST on the cell proliferation, protein synthesis, alkaline phosphatase activity, collagen synthesis, and apoptosis of the osteoblast. Results : 1. ST increased the proliferation of osteoblast, and restored the decreased cell number in glucocorticoid (GC)-treated osteoblast. 2. ST increased protein synthesis of osteoblast, and restored the decreased protein synthesis in GC-treated osteoblast. 3. ST increased ALP activity of osteoblast, and restored the decreased enzyme activity in GC-treated osteoblast. 4. ST increased collagen synthesis of osteoblast, and restored the decreased collagen synthesis in GC-treated osteoblast. 5. ST did not change the survival rate of osteoblast, but increased the survival rate in GC-treated osteoblast. Conclusions : It is concluded that ST might reduce the osteoporosis resulted from augumentation of osteoblast proliferation.

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Development of A Validation System For Automatic Radiopharmaceutical Synthesis Process Using Network Modeling (방사성의약품 합성 프로세스 검증을 위한 네트워크 모델링)

  • Lee, Cheol-Soo;Heo, Eun-Young;Kim, Jong-Min;Kim, Dong-Soo
    • IE interfaces
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    • v.24 no.3
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    • pp.187-195
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    • 2011
  • The automatic radiopharmaceutical module consists of several 2-way valves, couple of syringes, gas supply unit, heating(cooling) unit and sensors to control the chemical reagents as well as to help the chemical reaction. In order to control the actuators of radiopharmaceutical module, the process is tabulated using spread sheet as like excel. Unlike the common program, a trivial error is too critical to allowed in the process because the error can lead to leak the radioactive reagent and to cause the synthesis equipment failure during synthesizing. Hence, the synthesis process has been validated using graphic simulation while the operator checks the whole process visually and undergoes trial and error. The verification of the synthesis process takes a long time and has a difficulty in finding the error. This study presents a methodology to verify the process algebraically while the radiopharmaceutical module is converted to the network model. The proposed method is validated using actual synthesis process.