• Title/Summary/Keyword: Synergy effects

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Effect of Customer-acquisition Orientation on Salespeople's Performance in Distribution of Pharmaceuticals

  • CHO, Yeonjin;JEON, Jin-A
    • Journal of Distribution Science
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    • v.20 no.10
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    • pp.119-129
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    • 2022
  • Purpose: The purpose of this study was to investigate sales managers' strategic focus on customer acquisition, specifically its effect on salespeople's performance. In addition, this study aimed to determine how salespeople's interpersonal skills, salesmanship skills, and technical knowledge affect the relationship between customer-acquisition management and salespeople's performance. Research design, data, and methodology: This study conducted a survey of 310 salespeople working at pharmaceutical companies. A structural equation modeling approach was applied to test the main effects and interaction effects using AMOS. Results: The results indicated that both managers' customer-acquisition orientation and salespeople's salesmanship skills and technical knowledge positively affected the latter's performance. Further, it was found that the higher the technical knowledge of the salesperson, the greater the effect of the customer-acquisition orientation on sales performance. Conclusions: Sales managers should enable salespeople to quickly acquire technical knowledge with respect to the market, products, competitors, and company policy so that they can bring greater synergy to the customer-acquisition orientation.

Efficiency Effects of Mergers in the Korean Pharmaceutical Industry (국내 제약산업의 합병효과 분석)

  • Lee, Cheolhaeng;Cho, Keuntae
    • Journal of the Korean Operations Research and Management Science Society
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    • v.42 no.3
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    • pp.35-49
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    • 2017
  • The main objective of this paper is to empirically analyze the efficiency effects of mergers on Korean pharmaceutical firms and suggests managerial or policy implications for managers or policy makers. This study selects non-merging control firms close to the size of merging firms, as well as a set of merging firms, and measures the effects of mergers on efficiency three years before and after the merger using the non-parametric data envelopment analysis (DEA) method. To compare the differences of efficiency means among several groups, Wilcoxon rank sum test or Wilcoxon signed rank test is used. It showed that the long-term effects after the merger appeared partially. Furthermore, it was observed that there was no difference statistically in the efficiency between merging and non-merging firms. Also, there was no difference statistically in the efficiency between the pre- and post-merger periods. In conclusion, there was not any observed synergy effect through group (or affiliated) mergers between affiliates or related mergers for Korean pharmaceutical firms.

Anti-aging Effects of Cedrol and Collagen-derived Peptide (세드롤과 콜라겐 유래 펩타이드의 피부노화 개선효과)

  • Ryu, Jong Seong;Cho, Hwan Il;Won, Ji Hee;Jeon, Mi Na;Kwon, Oh Sun;Won, Bo Mi;Lim, Jun Man;Lee, Sang Hwa
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.41 no.3
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    • pp.229-235
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    • 2015
  • Skin aging is the phenomena finally expressed on the skin surface and related to the changes in the microstructure of the skin texture. Which is resulted in wrinkle formation and uneven tone of skin and so on. In this study, the synergy effect of Cedrol and a collagen-derived peptide in type III collagen synthesis was evaluated by in vitro test. The physiological skin state of 22 female volunteers was measured after using the cosmetics for 4 weeks. Results showed that Cedrol and a collagen-derived peptide had the excellent synergy effect in type III collagen synthesis. The cosmetics improved skin microrelief, star configurations, skin gloss, skin tone, hydration and elasticity except skin lightening. In conclusion, this study proved that Cedrol and collagen-derived peptide had the synergy effect of type III collagen synthesis in the cell level and cosmetics with those was improved skin aging in human volunteer test.

The Comparative Efficacy of Colistin Monotherapy and Combination Therapy Based on in vitro Antimicrobial Synergy in Ventilator-associated Pneumonia Caused by Multi-drug Resistant Acinetobacter baumannii (다제내성 Acinetobacter baumannii 에 의한 인공호흡기연관 페렴에서 Colistin 단독요법과 시험관 내 상승작용에 근거한 병합요법간의 효능 비교)

  • Jang, Hang Jea;Kim, Mi-Na;Lee, Kwangha;Hong, Sang-Bum;Lim, Chae-Man;Koh, Younsuck
    • Tuberculosis and Respiratory Diseases
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    • v.67 no.3
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    • pp.212-220
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    • 2009
  • Background: Ventilator-associated pneumonia caused by multi-drug resistant Acinetobacter baumannii has been increasing and growing as a threat in intensive care units. Limited therapeutic options have forced clinicians to choose colistin with or without combination of other antibiotics. We tried to compare the effectiveness between colistin monotherapy and combination therapy based on in vitro synergistic tests. Methods: From January 2006 to December 2007 in medical ICU of a tertiary care hospital in Korea, We reviewed the medical records of patients treated with intravenous colistin due to ventilator-associated pneumonia caused by multi-drug resistant Acinetobacter baumannii. Results: A total of 41 patients were analyzed. 22 patients had been treated with colistin monotherapy and 19 patients with colistin and combination antibiotics that were found to have in vitro synergistic effects. Baseline characteristics were similar in both groups but the mean duration of colistin administration was significantly longer in the combination group (19.1${\pm}$11.2 days vs. 12.3${\pm}$6.8 days, p=0.042). There were no significant differences in outcome variables between the two groups. Conclusion: Combination treatment based on the in vitro antimicrobial synergy test did not show better outcomes compared with colistin monotherapy in VAP caused by multi-drug resistant A. baumannii.

Synergy effect for performance of anionic SDS/ADS mixtures with amphoteric and nonionic surfactants

  • Noh, Hongche;Kang, Taeho;Ryu, Ji Soo;Kim, Si Yeon;Oh, Seong-Geun
    • Journal of the Korean Applied Science and Technology
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    • v.33 no.3
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    • pp.449-458
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    • 2016
  • Detergency and surface active properties of mixed anionic surfactants with amphoteric and nonionic were investigated. Sodium dodecyl sulfate (SDS) and ammonium dodecyl sulfate (ADS) as anionic surfactants and cocamidopropyl betaine (CAPB) as an amphoteric surfactant were used. Nonionic surfactants, which are butyl glucoside (BG), octyl glucoside (OG), decyl glucoside (DG), lauryl dimethylamine oxide (AO) and saponin were also used. To study the synergy effects of mixed SDS/ADS anionic surfactant systems, amphoteric and nonionic surfactants were added into the mixed anionic surfactants. Investigated properties of surfactant mixtures were critical micelle concentration (CMC), surface tension (${\gamma}$), wettability. In addition, based on these properties, detergency of each sample was examined. Surfactant mixtures are anionics (SDS/ADS), anionic/amphoteric/nonionic (SDS/ADS/CAPB/saponin), and anionic/nonionic (SDS/ADS/BG/saponin, SDS/ADS/OG/saponin, SDS/ADS/DG/saponin, and SDS/ADS/AO/saponin). With the addition of amphoteric and nonionic to mixed anionic surfactants, CMC and ${\gamma}$ were decreased. Addition of CAPB, which is amphoteric, showed the best property at CMC and ${\gamma}$. Furthermore, as the chain length of hydrocarbon in alkyl glucosides was increased, the CMC and ${\gamma}$ were enhanced. However, the wettability did not exactly match up with CMC and ${\gamma}$. The surfactant mixture, which contained DG, showed the best performance at wetting time. Detergency was measured at various temperatures ($15^{\circ}C$, $30^{\circ}C$, $50^{\circ}C$). The cleaning performance was enhanced by increasing washing temperature. Moreover, detergency was influenced by not only CMC and ${\gamma}$ but also wettability. Although CMC and ${\gamma}$ were not minimum at surfactant mixture that included DG, the best cleaning performance showed in that sample.

Effect Analysis of Structural Reform of Korea Railroad - Focusing on Comparison of Operating Cost - (철도구조개혁 성과분석 -운영비용을 중심으로-)

  • Sung, Myoung-Joon;Suh, Sun-Duck
    • Proceedings of the KSR Conference
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    • 2009.05a
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    • pp.1395-1411
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    • 2009
  • The Korea railroad industry has experienced the operating deficit annually since 1980. And the ridership has been reduced since 1990. Therefore, a structural reform of the Korea railroad industry conducted at 2003. Basic principles of their structural reform are no differences among the Korea and advanced counties. But different outcomes depending on each country situation appears. These cost functions appear the existence of all economic of scale. And when increase the average transport distance annually, the average cost reduce annually. The results of structural reform by comparing before and after, the average cost was lower than previously. The Structural reform and the operation of the KTX, the two effects at the same time, the synergy effect has occurred. Because of the synergy effect, the performance is estimated to be larger. Due to the effective operation of structural reform that could reduce costs.

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A Study on Utilizing the Site and Building of Closed School as Evacuation Facilities for the Library (폐교 부지 및 건축물을 이용한 도서관의 대피시설로서 활용 방안에 관한 연구)

  • Noh, Younghee;Ro, Ji-Yoon
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.30 no.4
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    • pp.65-89
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    • 2019
  • This study explored the fact that libraries can be used as evacuation facilities, suggesting that existing libraries built not only strengthen their role and function as evacuation facilities but also need to be constructed or remodeled to meet the criteria for designation and operation of evacuation facilities. The use of closed schools was proposed to pursue economic efficiency and regional effects in building or remodeling, and the status of the evacuation facilities and closed school in Chungju was evaluated to check the effectiveness of these proposals, and closed school was assessed based on the capacity of the shelter. The three main points of discussion in this paper are as follows: ① Reconfirm what functions and roles the library are performing as an evacuation facility, and explore the advantages of using the library as an evacuation facility is used as an evacuation facility. ② Review and discuss the synergy by the role of the library and the closed schools. ③ Examine and discuss the synergy between these roles of the library and the closed school.

A Study on Antibacterial Activity of Daehwanggeonwoo-san(Dahwangqianniu-san) Ethanol Extract against Methicillin-Resistant Staphylococcus Aureus (대황견우산(大黃牽牛散) 에탄올 추출물의 Methicillin 내성 Staphylococcus aureus에 대한 항균활성 연구)

  • Park, Ju-yeong;Na, Yong-su;Oh, Gong-cheon;Lee, Sang-mi;Choi, Byeong-kwon;Lee, Yoon-seung;Song, Yung-sun
    • Journal of Korean Medicine Rehabilitation
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    • v.28 no.2
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    • pp.21-35
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    • 2018
  • Objectives The objective of this study is to determine the antimicrobial effect of Daehwanggyeonu-san(Dahwangqianniu-san,DGE) and synergistic effects with antibiotics oxacillin, ampicillin, and gentamicin against Methicillin-Resistant Staphylococcus aureus(MRSA). Methods The antibacterial activity of DGE extract was evaluated againest MRSA strains by using the Disc diffusion method, broth microdilution method(minimal inhibitory concentration; MIC), checkerboard dilution test. The checkerboard dilution test was used to examined synergetic effect of oxacillin, ampicillin, gentamicin, ciprofloxacin with DGE extract. Results DGE showed antimicrobial activity against MRSA with an MIC value of $125{\sim}250{\mu}g/mL$. In the checkerboard test, the interation of DGE with all tested antibiotics produced almost synergy or partial synergy against MRSA. Conclusions This study shows that DGE reduced the MICs of several antibiotics tested, and a remarkable antibacterial effect of DGE, with membrane permeability enhancers and ATP synthase inhibitors. This study can be a valuable source for the development of a new drug with low MRSA resistance.

Effects of Na2S, NaCl, and H2O2 Concentrations on Corrosion of Aluminum (AA1100의 부식에 미치는 Na2S, NaCl, H2O2 농도의 영향)

  • Lee, Ju Hee;Jang, HeeJin
    • Corrosion Science and Technology
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    • v.18 no.6
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    • pp.312-317
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    • 2019
  • The objective of this study was to investigate the corrosion behavior of aluminum (AA1100) in a mixed solution of 0 ~ 0.1 g/L Na2S + 0.3 ~ 3 g/L NaCl + 0 ~ 10 mL/L H2O2. Potentiodynamic polarization tests were performed. Effects of solution compositions on corrosion potential, corrosion rate, and pitting potential of aluminum were statistically analyzed with a regression model. Results suggested that localized corrosion susceptibility of aluminum was increased in the solution with increasing concentration of NaCl because the pitting potential was lowered linearly with increasing NaCl concentration. On the contrary, H2O2 mitigated the galvanic corrosion of aluminum by increasing the corrosion potential. It also mitigated localized corrosion by increasing the pitting potential of aluminum. Na2S did not exert a noticeable effect on the corrosion of aluminum. These effects of different chemical species at various concentrations were independent of each other. Synergy or offset effect was not observed.

Study on Appropriate Mixing Ratios of Various Animal Meats with Other Ingredients to Improve the Palatability of Stock (육수 개발을 위한 수조육류 및 부재료의 최적 배합비율에 관한 연구)

  • Shin, Myung-Eun;Lee, Kyung-Hee
    • Journal of the Korean Society of Food Culture
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    • v.26 no.4
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    • pp.409-415
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    • 2011
  • The objective of this study was to develop a stock that can be used to make a variety of dishes. For this, stock was prepared with beef, chicken, and pork meat as animal meats as well as anchovy, mushroom, and sea tangle as other ingredients. The qualities of six[only four though] kinds of stocks made with beef only (B), beef and chicken (BC), beef and pork (BP), and beef added with chicken and pork (BCP), and seven kinds of stocks made with anchovy (A), mushroom (M), sea tangle (S), anchovy and mushroom (AM), anchovy and sea tangle (AS), mushroom and sea tangle (MS), and anchovy added with mushroom and sea tangle (AMS) were investigated by sensory evaluation. The most preferred stock made with animal meat was mixed with the most preferred stock made with other ingredients at a 5% level to test the synergistic effects of palatability. As a result, BCP stock and AMS stock obtained the highest scores for overall preference. BCP stock within the range of 30%-65% along with the mixed stock containing AMS (35%-70%) showed synergistic effects for palatability.