• 한국산학기술학회논문지
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• 제17권4호
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• pp.392-399
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• 2016

본 연구는 70세 이상 고령자들의 연령대에 따른 인구사회학적 및 건강관련행위 특성별 대사증후군의 분포를 비교해 보고자 2011~2014년도에 국민건강보험공단의 건강검진을 받았던 70세 이상 고령자 1,756명(남성 872명, 여성 884명)을 대상으로 대사증후군과 관련요인들 간의 관련성을 로지스틱 회귀분석을 통해 분석하였다. 연구결과, 대사증후군이 나타날 위험비는 남성보다 여성에서, 혼자 사는 군보다 가족과 함께 사는 군에서, 가정의 경제상태가 낮은 군보다 높은 군에서, 정상체중군보다 비만군에서, 뇌졸중 과거력이 없다는 군보다 있다는 군에서, 비흡연군보다 흡연군에서, 비음주군보다 음주군에서 유의하게 증가하였다. 따라서 조사대상자들의 대사증후군은 여러 인구사회학적 및 건강관련행위특성 변수에 따라 유의한 차이를 보이고 있음을 시사하고 있다.

• 한국융합학회논문지
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• 제12권5호
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• pp.385-392
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• 2021

본 연구는 대사증후군을 진단받은 대상자가 가지고 있는 진단지표와 건강행위간의 관련성을 파악함으로써 대사증후군 예방과 증진을 위한 근거자료를 제공하기 위해 시행되었다. 연구대상은 2017년 7월부터 2018년 7월까지 대전 지역 1개 대학병원과 4개의 보건소에 방문한 성인 633명이었으며, 분석방법은 SPSS/WIN 22.0 program으로 독립 t-test, ANOVA, Scheffe test, Pearson's Correlation 을 실시하였다. 연구결과 본 연구의 대상자는 연령, 종교유무, 교육수준, 진단지표의 수에 따라 건강행위의 차이를 보였다. 고혈당을 기준으로 대사증후군 유형을 구분했을 때, 진단유형에 따라 건강행위 중 스트레스 관리에 차이를 보였고, 고혈당이 있는 그룹에서 고지질혈증이 건강행위와 통계적으로 유의한 상관관계가 있는 것으로 나타났다. 따라서 대사증후군 증진을 위해 건강중재프로그램을 제공할 때 이러한 요인들을 고려하여 중재프로그램을 제공하는 것이 필요하다.

• 대한장애인치과학회지
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• 제14권1호
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• pp.36-40
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• 2018

CATCH 22 증후군(CATCH 22 Syndrome)은 선천성 심장기형, 비정상적인 안모, 흉선 형성부전, 구개열, 저칼슘혈증을 특징으로 하나 임상양상은 다양하게 나타난다. 본 증례는 치과 검진에 비협조적이고 다수의 치아 우식을 보이는 4세 5개월의 CATCH 22 증후군 환자를 전신마취 하에 효과적으로 치료하였기에 이를 보고하는 바이다. CATCH 22 증후군 환아는 선천적 심장기형을 동반하는 경우가 많아 의과적 자문 하에 치과 치료를 시행해야 한다. 간단한 치료의 경우 의과적 자문 하에 진정법 시행을 고려해 볼 수 있으나 불안정한 생징후를 보일 수 있어 보다 면밀한 모니터링을 요한다. CATCH22 환아의 전신상태에 대한 충분한 이해 및 술전 평가를 바탕으로 한 주의깊게 시행된 전신마취 술식은 다발성 치아우식의 치료에 있어서 보다 안전하고 효과적인 방법이 될 수 있을 것으로 사료된다.

• 대한소아치과학회지
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• 제21권2호
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• pp.605-610
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• 1994

Resricted opening of the mouth in children can be derived from a variety af extra and intra articular causes. A 5-year-old female patient with an elongated right coronoid process and with congenital missing teeth came to clinic for wearing of esthetic denture. A proper medical consultation and laboratory test had done for assessment a systemic syndrome related to her dental anomalies. The result was that her systemic findings dindn't accord specific signs and symptoms of Hallermann-Streiff syndrome. Unilateral coronoidectomy was fulfilled to improve mouth opening and subsequently endodontic and restorative procedure. Maxillary partial denture was delivered for esthetic problem. The periodic recall medical/dental check-up are recommended.

• JSTS:Journal of Semiconductor Technology and Science
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• 제16권4호
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• pp.488-496
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• 2016

This paper presents a low-complexity non-iterative soft-decision Bose-Chaudhuri-Hocquenghem (SD-BCH) decoder architecture and design technique for wireless body area networks (WBANs). A SD-BCH decoder with test syndrome computation, a syndrome calculator, Chien search and metric check, and error location decision is proposed. The proposed SD-BCH decoder not only uses test syndromes, but also does not have an iteration process. The proposed SD-BCH decoder provides a 0.75~1 dB coding gain compared to a hard-decision BCH (HD-BCH) decoder, and almost similar coding gain compared to a conventional SD-BCH decoder. The proposed SD-BCH (63, 51) decoder was designed and implemented using 90-nm CMOS standard cell technology. Synthesis results show that the proposed non-iterative SD-BCH decoder using a serial structure can lead to a 75% reduction in hardware complexity and a clock speed 3.8 times faster than a conventional SD-BCH decoder.

• Journal of Neurogastroenterology and Motility
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• 제24권4호
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• pp.603-613
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• 2018

Background/Aims Functional dyspepsia (FD) is one of the most common gastrointestinal disorders, and FD imposes social and economic burden worldwide. The aim of this study is to identify the prevalence and risk factors of FD in health check-up population in tertiary centers in Korea. Methods A nationwide multicenter prospective study was performed at 9 tertiary healthcare centers in Korea between September 2016 and June 2017. A total of 2525 subjects were investigated based on endoscopic findings and questionnaires with the Rome III criteria, and Helicobacter pylori serology (IgG). Results A total of 1714 subjects without organic disease were enrolled. The mean (${\pm}SD$) age was 51.5 (${\pm}12.7$) years, and 917 patients (53.5%) were female. The proportion of H. pylori seropositivity was 51.0% (874/1714). The prevalence of FD was 10.3% (176/1714), and the subtypes of postprandial distress syndrome alone, epigastric pain syndrome alone, and postprandial distress syndromeepigastric pain syndrome overlap were 4.8%, 3.0%, and 2.5%, respectively. Multivariate analysis showed that female gender (OR, 1.58; 95% CI, 1.14-2.21) and education below college level (OR, 1.45; 95% CI, 1.01-2.07) were related to FD. Multivariate analysis based on age 60 showed female gender as a significant (OR, 2.90; 95% CI, 1.06-7.94) factor in the group ${\geq}60$ years. Conclusions The prevalence of FD was 10.3% in the health check-up population in Korea. Female sex and education below college level were risk factors for FD. Female sex is a risk factor for FD in old age, underscoring the need for close attention in this age group.

• IMMUNE NETWORK
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• 제4권3호
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• pp.184-189
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• 2004

Background: Hu syndrome, a neurological disorder, is characterized by the remote effect of small cell lung cancer on the neural degeneration. The suspicious effectors for this disease are anti-Hu autoantibodies or Hu-related CD8+ T lymphocytes. Interestingly, the same effectors have been suggested to act against tumor growth and this phenomenon may represent natural tumor immunity. For these diagnostic and therapeutic reasons, the demand for antibodies against Hu protein is rapidly growing. Methods: Polyclonal and monoclonal antibodies were generated using recombinant HuR protein. Western blot analyses were performed to check the specificity of generated antibodies using various recombinant proteins and cell lysates. Extracellular stimuli for HuR expression had been searched and HuR-associated proteins were isolated from polysome lysates and then separated in a 2-dimensional gel. Results: Polyclonal and monoclonal antibodies against HuR protein were generated and these antibodies showed HuR specificity. Antibodies were also useful to detect and immunoprecipitate endogenous HuR protein in Jurkat and BJAB. This report also revealed that TNF-${\alpha}$ treatment in BJAB up-regulated HuR expression. Lastly, protein profile in HuR-associated mRNAprotein complexes was mapped by 2-dimensional gel electrophoresis. Conclusion: This study reported that new antibodies against HuR protein were successfully generated. Currently, project to develop a diagnostic kit is in process. Also, this report showed that TNF-${\alpha}$ up-regulated HuR expression in BJAB and protein profile associated with HuR protein was mapped.

• 기본간호학회지
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• 제16권2호
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• pp.171-180
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• 2009

Purpose: This study was done to examine the frequency of irritable bowel syndrome (IBS), entrance examination stress, mental health, and quality of life among adolescent women. Methods: A survey conducted to collect data from 925 adolescent women in Gyeonggi Province. The measurements included the Rome III criteria (to diagnose IBS), the entrance examination stress scale (to evaluate stress), symptom check list90R (SCL-90R to evaluate mental health), and World Health Organization Quality of Life Abbreviated Version (WHOQOL-BREF to evaluate quality of life). Frequency, $X^2$-tests, t-test, and analysis of variance (ANOVA) with the SPSS 16.0 program were used to analyze the data. Results: The frequency of IBS in the women was 22.8%. One hundred thirty eight women (65.4%) had the mixed constipation and diarrhea subtype of IBS. Compared to the women without IBS, those with IBS reported significantly higher scores on entrance examination stress scale, SCL-90R, all subscales of SCL-90R, and lower scores on WOLQOL-BREF. Conclusion: Nursing interventions targeting adolescent women with IBS should be developed in order to alleviate the associated stress and mental health and to promote quality of life.

• 성인간호학회지
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• 제26권2호
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• pp.244-252
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• 2014

Purpose: This study was aimed to examine the prevalence of metabolic syndrome (MetS) and cardiovascular risk factors among workers at small-sized companies having fewer than 50employees in Korea. Methods: A descriptive cross-sectional study was conducted using a secondary data analysis on workers' health examination data. Data from 21,784 employed workers were analyzed, including 16,488 males (mean age 38.7years)and 5,296 females (mean age 40.5 years). Participants were newly enrolled in annual health check-ups at a professional health clinic from 2009 to 2011. Logistic regression analysis was performed to identify age-adjusted gender specific predicting factors of MetS incidence. Results: The prevalence of MetS was 13.4% in male and 7.7% in female workers. Logistic regression analysis showed that, when age was adjusted for, family history of cardiovascular disease (CVD) was a predicting factor in both male and female workers. For male workers, heavy alcohol drinking and non-manual occupation (office workers/drivers) predicted MetS. Conclusion: Health care providers should screen for MetS periodically in small work places especially for those with a family history of CVD. Educational counseling needs to be given to male workers with sedentary occupations with an aim to reduce heavy drinking and encourage lifestyle modification.

• 성인간호학회지
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• 제20권5호
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• pp.685-696
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• 2008

Purpose: This study was performed to examine the frequency of irritable bowel syndrome(IBS), perceived stress, and mental health among community-dwelling women. Methods: This study conducted a survey to collect data on 869 women in Seoul and Gyeonggi-do. The measurements included the Rome III criteria(to diagnose IBS), the Global Assessment Recent Stress(GARS scale to evaluate perceived stress), and symptom check list 90R(SCL-90R to evaluate psychological distress). Data were analyzed using SPSS 15.0 program by frequency, $x^2$-tests, t-test, and analysis of variance(ANOVA). Results: The frequency of IBS in women was 15.1%. Eighty-six women(65.6%) had mixed constipation and diarrhea subtype of IBS. Compared to the women without IBS, those with IBS reported significantly higher scores on GARS, all subscales of GARS, SCL-90R, all subscales of SCL-90R, and the global severity index(GSI). No significant differences were observed among stress, mental health, and the IBS subtypes. Conclusion: Nursing interventions targeting women with IBS should be developed in order to reduce the associated stress and psychological distress.