• 대한조선학회 특별논문집
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• 대한조선학회 2006년도 특별논문집
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• pp.112-121
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• 2006

The vertical displacement of a ship on the basis of the sea level is an important parameter for its stability and control. To indicate the displacement on operating conditions, "draft marks" are carved on the hull of the ship in various ways. One of the methods is welding. The position, shape and size of the marks are specified on the shipbuilding rules by classification societies to be checked by shipbuilders. In most cases, high-skilled workers do the welding along the drawing for the marks and welding bead becomes the marks. But the inaccuracies due to human errors and high labor cost increase the needs for automating the work process of the draft marks. In the preceding work, an indoor robot was developed for automatic marking system on flat surfaces and the work proved that the robot welding was more effective and accurate than manual welding. However, many parts of the hull structure constructed at the outdoor are cowed shapes, which is beyond the capability of the robot developed for the indoor works on the flat surface. The marking on the curved steel surface requiring the 25m elevations is one of the main challenges to the conventional robots. In the present paper, the robot capable of climbing vertical curved steel surfaces and performing the welding at the marked position by effectively solving the problems mentioned earlier is presented.

• Asian-Australasian Journal of Animal Sciences
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• 제15권8호
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• pp.1110-1114
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• 2002

The animal production sector in Jordan is characterized by shortages of locally produced feedstuffs derived from rangeland, forage plants or from human food crops as by products. This is exacerbated by insufficient rainfall, overgrazing, early grazing and high stocking rate. Thus, subject to these constraints, other technological improvements are highly desirable to meet the needs of crop growth and animal production. Alternative adapted technologies are also desirable in order to meet the increased demand for red meat in relation to population growth along with the changes in the price subsidy for feedstuff. The technologies are those, which have been introduced to the animal production sector, obtained in agricultural research stations besides on-farm demonstrations. They include technologies suited for increasing birth and twining rates, synchronizing the mating period, introducing the early weaning method, and animal feed and sheep production. Economic assessments conducted in this study demonstrate promising results of hormonal and nutritional practices in improving production efficiency of Awassi sheep in Jordan. Jordanian published data between 1991 and 1998 were used. The examined practices were: 1) use of PMSG in estrus synchronization in ewes, 2) introduction of early lamb weaning program, 3) supplementation with $AD_3E$ for ewes and 4) the use of agro-industrial feed block as a feed supplement for grazing lambs. Production data were then subjected to partial budgeting for economical evaluation. The use of PMSG outperformed the control groups in fertility and net returns per ewe by US$ 8.36/ewe. The early weaning of lambs increased the net returns by US$ 3.90/lamb. The injection with vitamin $AD_3E$ showed an average additional net return of US$ 5.66/ewe. Feeding agriculture by-product blocks improved weight gain in the feed block groups and resulted in additional net returns of US$ 3.5/lamb. The economic viability and reproductive performance indicators demonstrate that efforts should be undertaken to disseminate these new practices in the development program.

• 한국통신학회논문지
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• 제37권4C호
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• pp.297-306
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• 2012

최근 유헬스케어 시스템은 IT 기술과 의료서비스가 접목되면서 사용 범위가 점점 넓어지고 있다. 그러나 유헬스케어 시스템 중 체내삽입형 장치를 사용하는 환자의 경우, 환자의 프라이버시 예방과 안전한 접근 제어에 대한 대비책이 마련되어 있지 않아 그에 따른 프라이버시 보호 문제가 대두되고 있다. 본 논문에서는 체내삽입형 장치를 사용한 환자의 프라이버시를 보장하기 위해서 환자 정보를 가상화한 후 환자의 상태값과 수행값을 동기화함으로써 제3자의 불법적 접근을 예방할 수 있는 환자 프라이버시 보호 프로토콜을 제안한다. 제안된 프라이버시 보호 프로토콜은 사전에 관리 서버에 등록된 병원(의사, 간호사, 약국 등)의 권한정보에 따라 체내삽입형 장치를 부착한 환자의 개인정보의 열람범위를 제한하여 병원관계자의 불법적 업무 수행을 예방한다. 특히, 체내삽입형 장치와 게이트웨이 역할을 하는 가상장치는 접근 허가가 승인된 환자 정보 이외에 허가받지 않은 정보에 대해서 제 3자가 쉽게 접근하지 못하도록 환자의 상태값과 수행값을 동기화함으로써 환자의 프라이버시 관리의 효율성을 향상시키고 있다.

• 한국정보통신학회논문지
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• 제1권2호
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• pp.145-158
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• 1997

멀티미디어 동기화는 분산 멀티미디어 환경에서 주어진 시간내에 멀티미디어 데이터를 네트워크를 통해 동기식으로 전송하여 연속적인 멀티미디어 프리젠테이션을 보장하는데 필요한 기법이다. 본 논문은 멀티미디어 응용의 서비스 품질 및 특성을 이용하여 지연에 민감한 멀티미디어 데이터를 서비스 품질의 저하없이 동기식으로 전송 및 출력할 수 있도록 하는 미디어 간 및 미디어 내 동기화 기법을 제안한다. 제안된 기법에서는 네트워크 지연 변동으로 인하여 미디어 데이터의 전송 시간을 예측할 수 없고 지역 및 원격 시스템 사이에 동기화를 위한 전역 클럭을 이용할 수 없는 환경에서 스큐와 지터로 인한 비동기 현상을 방지하기 위해 논리 시간 시스템, 동적 버퍼 관리 기법, 동기화 구간의 조정 기법을 적용하였다. 특히, 최대 전송 지연허용 시간, 최대 패킷 손실률 등과 같은 프리젠테이션 품질을 이용하여 네트워크 지연 변동을 흡수할 수 있고 동기화에 필요한 버퍼 요구량을 줄일 수 있는 방안을 제시하였다.

• 정보과학회 논문지
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• 제42권1호
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• pp.1-6
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• 2015

스마트기기는 일상에서 많이 사용되고 있으나, 스마트기기 스크린 크기는 멀티미디어 콘텐츠를 감상하기에는 여전히 작다. 그래서 여러 대의 스마트 기기를 이용해서 멀티비전을 구성하게 되면 스크린을 확장해서 볼 수는 있지만 기기 상호간에 발생하는 시간지연에 의해 영상 및 소리의 불일치가 발생할 수 있다. 본 논문에서는 이러한 시간 지연을 최소화 시킬 수 있는 두 가지 동기화 기법을 구현 및 검증하여 효율적인 기법을 최종안으로 제안한다. 이 기법은 Controller의 재생 시간을 기준으로 하여 Viewer 역할을 하는 기기가 자신의 재생 시간을 반복 조정하여 재생 동기화 하는 방법이다. 이 기법을 사용하면 네트워크 품질이나 단말기 제조사에 관계없이 여러 대의 스마트 기기로 멀티비전을 구성하여 확장된 크기의 멀티미디어 콘텐츠를 감상할 수 있을 것으로 기대된다.

• Molecules and Cells
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• 제39권7호
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• pp.536-542
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• 2016

Interleukin-17A is a member of the IL-17 family, and is known as CTLA8 in the mouse. It is produced by T lymphocytes and NK cells and has proinflammatory roles, inducing cytokine and chemokine production. However, its role in tumor biology remains controversial. We investigated the effects of locally produced IL-17A by transferring the gene encoding it into CT26 colon cancer cells, either in a secretory or a membrane-bound form. Expression of the membrane-bound form on CT26 cells dramatically enhanced their proliferation in vitro. The enhanced growth was shown to be due to an increased rate of cell cycle progression: after synchronizing cells by adding and withdrawing colcemid, the rate of cell cycle progression in the cells expressing the membrane-bound form of IL-17A was much faster than that of the control cells. Both secretory and membrane-bound IL-17A induced the expression of Sca-1 in the cancer cells. When tumor clones were grafted into syngeneic BALB/c mice, the tumor clones expressing the membrane-bound form IL-17A grew rapidly; those expressing the secretory form also grew faster than the wild type CT26 cells, but slower than the clones expressing the membrane-bound form. These results indicate that IL-17A promotes tumorigenicity by enhancing cell cycle progression. This finding should be considered in treating tumors and immune-related diseases.

• 한국발생생물학회지:발생과생식
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• 제21권1호
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• pp.47-54
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• 2017

Unlike mouse results, cloning efficiency of nuclear transfer from porcine induced pluripotent stem cells (piPSCs) is very low. The present study was performed to investigate the effect of cell cycle inhibitors on the cell cycle synchronization of piPSCs. piPSCs were generated using combination of six human transcriptional factors under stem cell culture condition. To examine the efficiency of cell cycle synchronization, piPSCs were cultured on a matrigel coated plate with stem cell media and they were treated with staurosporine (STA, 20 nM), daidzein (DAI, $100{\mu}M$), roscovitine (ROSC, $10{\mu}M$), or olomoucine (OLO, $200{\mu}M$) for 12 h. Flow Cytometry (FACs) data showed that piPSCs in control were in G1 ($37.5{\pm}0.2%$), S ($34.0{\pm}0.6%$) and G2/M ($28.5{\pm}0.4%$). The proportion of cells at G1 in DAI group was significantly higher than that in control, while STA, ROSC and OLO treatments could not block the cell cycle of piPSCs. Both of viability and apoptosis were affected by STA and ROSC treatment, but there were no significantly differences between control and DAI groups. Real-Time qPCR and FACs results revealed that DAI treatment did not affect the expression of pluripotent gene, Oct4. In case of OLO, it did not affect both of viability and apoptosis, but Oct4 expression was significantly decreased. Our results suggest that DAI could be used for synchronizing piPSCs at G1 stage and has any deleterious effect on survival and pluripotency sustaining of piPSCs.

• 한국수정란이식학회지
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• 제31권3호
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• pp.255-260
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• 2016

The aim of this study is to evaluate the effects of vitamin or mineral supplements on the conception rates of dairy heifers when replacing the last injection of GnRH with hCG in ovsynch protocol (experiment 1) and also to investigate whether the estrus synchronization treatment in the heifer stage affects the conception rates after $1^{st}$ parturition (experiment 2). In experiment 1, 50 heifers were randomly assigned into 3 groups: 20 heifers each in groups 1 and 2, and 10 in group 3. All three groups were treated with an intramuscular injection of GnRH on day 0 (day 0 = the day of program start), $PGF_{2{\alpha}}$ on day 7 and hCG on day 9, and were inseminated on day 10, 12~16h after hCG injection. In group 1 (vitamin group), the heifers were treated with an intramuscular injection of 5 ml of vitamin-ADE $500^{(R)}$, and group 2 (mineral group) was treated twice with an intramuscular injection of 30 ml of mineral supplement-LAPTOVET$^{(R)}$ on a one-week interval beginning on the day of hormone treatment (day 0 and day 7 respectively). Group 3 (control) was treated only with hormones. Pregnancy diagnosis was performed by ultrasonography through a rectal probe. First service conception rates (FSCR) and average services per conception (ASPC) were recorded for all subjects. Of the total 50 heifers, 6 (2 in group 1, 3 in group 2, and 1 in group 3) heifers were eliminated due to accidents during experiment 1. FSCRs were 58.8% (10/17), 66.7% (12/18) and 44.4% (4/9) in groups 1, 2 and 3, respectively. ASPCs were $1.53{\pm}0.72$, $1.27{\pm}0.59$ and $1.63{\pm}0.74$ in groups 1, 2 and 3, respectively. Although there were no significant difference between the groups, relatively good results (higher FSCR and lower ASPC) were obtained in both group 1 and 2. In experiment 2, 11 primiparous cows from group 2 of experiment 1 in heifer stage which had been treated both with the hormones for estrus synchronizing and mineral supplements (ES group), and 12 primiparous cows treated only with minerals (non-ES group) were compared to examine the effects of estrus synchronization program on conception rates after $1^{st}$ parturition. Following the examination, postpartum ASPCs were $1.55{\pm}0.82$ and $2.17{\pm}1.47$ in ES group and non-ES group, respectively. The postpartum average days open (ADO) were $116{\pm}56$ and $197{\pm}93$ in ES group and non-ES group, respectively. Although there were no significant difference between the two groups, desirable results (lower ASPC and shorter ADO) were found in ES group after $1^{st}$ parturiton. In conclusion, experiment 1 indicates that vitamin or mineral supplement with ovsynch protocol may have some positive effect on FSCR and ASPC of dairy heifers, and in experiment 2, ES program in heifer stage had a positive effect on ASPC and ADO following $1^{st}$ parturition.

• 한국지구과학회지
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• 제34권6호
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• pp.588-601
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• 2013

최근 지구물리 물리탐사 분야에서 경사각과 방위각 정보는 시추공 물리검층 및 물리탐사 자료보정을 위한 시추공 편차검층, 이동형 실시간 자료획득 시스템, 기타 지구물리 모니터링 시스템 등 다양하게 활용되면서 그 중요성이 높아지고 있다. 특히 최근 셰일가스의 개발이 가능하게 한 방향시추 기술에서도 경사각과 방위각 정보는 필수일 정도로 그 응용범위가 매우 넓다. 따라서 여러 분야에 응용될 수 있는 경사각과 방위각 측정 시스템의 초소형 옥외 저전력 운용이 절실해졌다. 본 논문에서는 최신 CMOS 저전력, 고성능 MCU 및 멤스(MEMS) 자세방위기준장치(AHRS)를 도입하여 초소형, 저전력으로 제작된 다용도 야외시험용 실시간 경사각과 방위각 연속 측정 시스템 개발 연구의 결과를 제시하고자 한다. 시스템은 최소 지름 42 mm의 존데 내에 설치될 수 있도록 초슬림 형태로 제작되었으며 실시간 데이터 획득이 가능할 뿐만 아니라 엔코더, DGPS 연동으로 운용 확장이 가능하여 다양한 응용이 기대된다.