• Title/Summary/Keyword: Symptom appearance

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The Quality of Life after Lymphaticovenous Anastomosis in 118 Lower Limb Lymphedema Patients

  • Jin Geun Kwon;Yeongsong Kim;Min Young Jang;Hyunsuk Peter Suh;Changsik John Pak;Vaughan Keeley;Jae Yong Jeon;Joon Pio Hong
    • Archives of Plastic Surgery
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    • v.50 no.5
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    • pp.514-522
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    • 2023
  • Background This is a prospective study on 118 patients who underwent lymphaticovenous anastomosis (LVA) due to secondary lower limb lymphedema between January 2018 and October 2020 to evaluate patients' quality of life (QOL) using the Quality of Life Measure for Limb Lymphedema (LYMQoL) questionnaire. Methods The outcome measurement included the LYMQoL leg scoring system tool evaluating the function, appearance, symptom, mood, and overall outcome. In addition, correlation analysis was performed for three factors: based on International Society of Lymphology (ISL) stages, disease duration, and amount of volume reduction. Results The LYMQoL tool overall satisfaction score significantly increased at all intervals from 4.4 ± 0.2 preoperative to 6.5 ± 0.3 postoperative at 12 months (p < 0.001). Significant findings were seen for each domain scores compared preoperatively and at 12 months: function score (18.6 ± 0.5 to 15.4 ± 0.6), appearance score (17.8 ± 0.5 to 16.0 ± 0.6), symptom score (11.8 ± 0.3 to 8.9 ± 0.4), and mood score (14.5 ± 0.4 to 11.4 ± 0.5; p < 0.05). The correlation analysis between improvement of the overall score and the ISL stage (p = 0.610, correlation coefficient [r] = -0.047), disease duration (p = 0.659, r = -0.041), and amount of limb volume reduction (p = 0.454, r = -0.070) showed no statistical significance. Conclusion The QOL of secondary lower limb lymphedema patients was significantly improved after LVA regardless of the severity of disease, duration of disease, and amount of volume reduction after LVA. Understanding the patient-reported outcome measurement will help the surgeons to manage and guide the expectations of the patients.

Title of Article: Current status of viral disease spread in Korean horn beetle, Allomyrina dichotoma (Coleoptera: Scarabeidae)

  • Lee, Seokhyun;Kim, Hong-Geun;Park, Kwan-ho;Nam, Sung-hee;Kwak, Kyu-won;Choi, Ji-young
    • International Journal of Industrial Entomology and Biomaterials
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    • v.31 no.2
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    • pp.70-74
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    • 2015
  • The current market size of insect industry in Korea is estimated at 300 million dollars and more than 500 local farms are related to many insect industry. One of the strong candidates for insect industry is Korean horn beetle, Allomyrina dichotoma. Early this year, we reported a viral disease extremely fatal to A. dichotoma larvae. While we were proceeding a nationwide investigation of this disease, it was informed that similar disease symptom has been occurred occasionally during past over 10 years. The symptom can be easily confused with early stage of bacterial infection or physiological damage such as low temperature and high humidity. A peroral infection with the purified virus to healthy larvae produced a result that only 21% of larvae survived and became pupae. Although some of the survived adult beetle was deformational, many of them had no abnormal appearance and even succeeded in mating. Later, these beetles were examined if they were carrying the virus, and all except one were confirmed as live virus carrier. This implies that these beetles may fly out and spread the disease to the nature. We found the evidence for this possibility by collecting a few wild A. dichotoma larvae which were virus infected, near two local farms rearing A. dichotoma larvae. So far, transovarial transmission of this virus to the eggs, or horizontal transmission to other commercially reared insects is not known yet.

Transgenic cucumber expressing the 54-kDa gene of Cucumber fruit mottle mosaic virus is highly resistance and protect non-transgenic scions from soil infection

  • Gal-On, A.;Wolf, D.;Antignus, Y.;Patlis, L.;Ryu, K.H.;Min, B.E.;Pearlsman, M.;Lachman, O.;Gaba, V.;Wang, Y.;Yang. J.;Zelcer, A.
    • Proceedings of the Korean Society of Plant Pathology Conference
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    • 2003.10a
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    • pp.148.2-149
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    • 2003
  • Cucumber fruit mottle mosaic tobamovirus (CFMMV) causes severe mosaic symptoms with yellow mottling on leaves and fruits, and occasionally severe wilting of cucumber plants. No genetic source of resistance against this virus has been identified. The genes coding for the coat protein or the putative 54-kDa replicase were cloned into binary vectors under control of the SVBV promoter. Agrobacterium-mediated transformation was peformed on cotyledon explants of a parthenocarpic cucumber cultivar with superior competence for transformation. R1 seedlings were evaluated for resistance to CFMMV infection by lack of symptom expression, back inoculation on an alternative host and ELISA. From a total of 14 replicase-containing R1 lines, 8 exhibited immunity, while only 3 resistant lines were found among a total of 9 CP-containing lines. Line 144 homozygous for the 54-kDa replicase was selected for further resistance analysis. Line 144 was immune to CFMMV infection by mechanical and graft inoculation, or by root infection following planting in CFMMV-contaminated soil. Additionally, line 144 showed delay of symptom appearance following infection by other cucurbit-infecting tobamoviruses. Infection of line 144 plants with various potyviruses and cucumber mosaic cucumovirus did not break the resistance to CFMMV. The mechanism of resistance of line 144 appears to be RNA-mediated, however the means is apparently different from the gene silencing phenomenon. Homozygote line 144 cucumber as rootstock demonstrated for the first time protection of a non-transformed scion from soil inoculation with a soil borne pathogen, CFMMV.

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Appearance of globule leukocytes in tracheal and broncheal mucosa in Korean native cattle with pneumonia and rats experimentally infected with Klebsiella pneumoniae (폐렴우와 Klebsiella pneumoniae 실험적 감염 랫드의 기관 및 기관지 점막층에서 Globule leukocyte의 출현양상)

  • Park, Sang-joon;Lee, Cha-soo;Jeong, Kyu-shik
    • Korean Journal of Veterinary Research
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    • v.37 no.4
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    • pp.831-841
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    • 1997
  • The study was aimed at identifying the globule leukocytes (GL) of tracheal mucosa layer of Korean native cattle showing symptom of pneumonia which have died as enterotoxemia and normal Korean native cattle in Kyungpook local area. In another set of experiment, Isolated Klebsiella pneumoniae from suddenly died cattle specimens was subjected to rat for a determining globule leukocyte appearance by using histochemical and immunohistochemical method. In histochemical study, globule leukocytes generally was existed in all the case of postmortem of Korean native cattle and 3 heads of slaughtered cattle which showing symptoms of pneumonia and it showed significant increase in tracheal mucosa of rats experimentally infected with Klebsiella pneumoniae. These increased number of globule leukocytes was moderately remained on early infection stage and gradually decreased in timedependent manner after infection. The granule patterns were also determined as an acidmucopolysaccharide. In immunohistochemical study, serotonin intensity in the treacheal mucosaepithelial cells of rat experimentally infected observed a strong immunoreactivity during early infection and gradually decreased in dependent of infection stage while no IgE immunoreactivity observed. These data show that globule leukocytes were increased in a pneumonia, therefore it was considered as a valuable cell that was associated with early stage of inflammatory response.

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A Study on the Geostatistical Evaluation of Urban and Environmental Structure of Taegu Metropolitan Region (대구광역도시권의 지리통계적 도시환경구조 평가에 관한 연구)

  • Park, In-Hwan;Jang, Gab-Sue
    • Journal of Environmental Impact Assessment
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    • v.8 no.3
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    • pp.1-11
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    • 1999
  • This study was carried out to evaluate urban environmental structure in Taegu metropolitan region(TMR) with factor analysis, fuzzy set theory, geostatistic and geographic information system(GIS). The factor analysis could choose the representative one out of multiple variables and simplify the evaluation of the urban environmental structure. The fuzzy approach is an attempt to model an aspect of human thinking previously neglected; it starts from the premise that humans don't represent classes of objects as fully disjoint but rather as sets where transitions from membership to non-membership is gradual. The Geographic Information System(GIS) could connect attributes of factor scores derived from factor analysis to digital map by a method so called 'Spatial join'. The results obtained were as follows: Urbanization appearance was concentrated in the large cities, and this appearance was partial extremely, therefore, there has been a structural gap between urban area and agricultural area which was unified into the urban area. All inclinations didn't become worse after sudden urbanization. For example, suburban agriculture was developed as a large scale in the region near the large cities. Then it encouraged farmers in changing their old cultivating methods to the latest ones. But many districts in urban fringe had symptom of urbanization, the districts which were located between large cities have been developed gradually because of urban sprawl, and played a role in connecting each city. Therefore, due to the urbanization, forestry area and agricultural land, well conserved in the agricultural town, could be easily destroyed. In a different way with the urbanization of the Seoul metropolitan region, that of TMR was centralized upon the center of each city, and it was also very partial. But, because so many regions have the potentiality of urbanization, hereafter, the urbanization process in each region is likely to be different multifariously according to the urban management methods.

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The King Jeong-Jo's Sasang Constitution, Which wsa Based on the Annals of the Choson Dynasty(朝鮮王朝實錄), Hong Je jun Se(弘齋全書), GukSoBoGam(國朝寶鑑) (문헌을 통해 살펴 본 정조의 사상체질)

  • Kim, Dal-Rae;Kim, Sun-Hyung
    • Journal of Sasang Constitutional Medicine
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    • v.21 no.1
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    • pp.44-52
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    • 2009
  • 1. Objectives Jeong-Jo's death has many mistery. So we understand rightly Jeong-Jo's death. we inspect closely medical records of 20 days before death(in The Annals of the Choson Dynasty(朝鮮王朝實錄), Hong Je Jun Se(弘齋全書), GukSoBoGam(國朝寶鑑). We understand medical treatment before death. It is based on Jeong-Jo's Constitution. So we trace the cause of a Jeong-Jo's death rightly. 2. Methods According to The Annals of the Choson Dynasty(朝鮮王朝實錄), Hong Je Jun Se(弘齋全書) GukSoBoGam(國朝寶鑑). We found out Jeoung-Jo's Sasang constitutional elemet. We point on Jeoung-Jo's nature and emotion, temperament and talent, features and way of speaking, physical appearance, healthy state, ordinary symptom, pathological syndromes and pharmacology. so documentary records was worthy of notice. 3. Results and conclusions 1. Jeong-Jo has prominent cheekbones,flat face. It belong to Tae-eum. 2. Jeong-Jo's physical appearance is mild,around,large. It belong ro Tae-eum. 3. Jeong-Jo's favorite food and herb were belong to Tae-eum interior febrile disease herb. which is Exhale Dispersing Qi 4. So even though Jeoung-Jo is Tae-eum, He had a weak body. It main cause that Smoking, insomnia, heave work, Hwa disease. 5. Jeong-Jo's is Interior febrile disease induced form the liver affected by heat in Tae-eumin

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Characterization and Partial Nucleotide Sequence Analysis of Alfalfa Mosaic Alfamoviruses Isolated from Potato and Azuki Bean in Korea

  • Jung, Hyo-Won;Jung, Hye-Jin;Yun, Wan-Soo;Kim, Hye-Ja;Hahm, Young-Il;Kim, Kook-Hyung;Choi, Jang-Kyung
    • The Plant Pathology Journal
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    • v.16 no.5
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    • pp.269-279
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    • 2000
  • Alfalfa mosaic alfamoviruses(AIMV) were isolated from infected potato (Solanum tuberosum) and azuki bean (Paseolus angularis) in Korea. Two AIMV isolated from potatoes were named as strain KR (AIMV-KR1 and KR2) and AIMV isolated from azuki bean was named as strain Az (AIMV-Az). Each isolated AIMV strain was characterized by using their host ranges, symptom developments, serological relations and nucleotide sequence analysis of coat protein (CP) gene. Strains KR1, KR2, and Az were readily transmitted to 20 of 22 inoculated plant species including bean, cowpea, tomato, tobacco, and potato. AIMV-KR1 and KR2 produced the typical symptoms like chlorotic or necrotic spots in Chenopodium quinoa and Solanum tuberosum cv. Superior. AIMV-Az caused bright yellow mosaic symptom and leaf malformation in Nicotiana glauca, which were different from the common mosaic symptom caused by AIMV-KR1 and KR2. Electron microscope observation of purified virus showed bacilliform virions containing a single-stranded plus-strand RNAs of 3.6, 2.6, 2.0 and 0.9 kbp in length, respectively, similar in size and appearance to those of Alfamovirus. In SDS-PAGE, the coat protein of the two viruses formed a consistent band that estimated to be about 24kDa. The CP genes of the AIMV strains, KR1, KR2, and Az have been amplified by RT-PCR using the specific primers designed to amplify CP gene from viral RNA-3, cloned and sequenced. Computer aided analysis of the amplified cDNA fragment sequence revealed the presence of a single open reading frame capable of encoding 221 amino acids. The nucleotide and peptide sequence of viral CP gene showed that strain KR1, KR2, and Az shared highest nucleotide sequence identities with AIMV strain 425-M at 97.7%, 98.2%, and 97.2%, respectively. CP gene sequences of two strains were almost identical compared with each other. Altogether, physical, serological, biological and molecular properties of the purified virus.

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Inoculum Sources to Generate High Mechanical Transmission of Barley yellow mosaic virus

  • Jonson, Gilda;Kim, Yang-Kil;Kim, Mi-Jung;Park, Jong-Chul;Hyun, Jong-Nae;Kim, Jung-Gon
    • The Plant Pathology Journal
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    • v.23 no.2
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    • pp.103-105
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    • 2007
  • Mechanical transmission of barley seedlings with barley yellow mosaic virus (BaYMV) is generally inefficient and is the major constraint for testing cultivar resistance to the virus. To explore mechanical transmission, BaYMV-infected barley plants were grown at different conditions and used as inoculum sources to seedlings of susceptible barley cultivar Baegdong. Extracts prepared from BaYMV-infected Baegdong plants at 47, 53, 74, and 90 days after symptom appearance (DASA) and grown at 10 and $12^{\circ}C$ gave 10, 30, 68 and 76% infection, respectively on inoculated susceptible barley cv. Baegdong seedlings. While Jinyangbori, another susceptible cultivar obtained 95% infection rate inoculated with extracts from 90 DASA disease source and grown at $10/12^{\circ}C$. However, low infection rates were obtained when the virus sources were grown in a greenhouse at $15-18^{\circ}C$. Our results indicate that longer incubation period and lower temperature are required for virus accumulation and stability.

A CLINICOPATHOLOGIC STUDY ON FIBROUS DYSPLASIA OF THE MAXILLOFACIAL REGIONS (악안면 부위에 발생한 섬유성 골이형성증에 대한 임상조직병리학적 연구)

  • PYO, Sung-Woon;Nam, Il-Woo
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.14 no.1_2
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    • pp.124-134
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    • 1992
  • Fibrous dysplasia is a benign pathologic condition of bone in which fibrous tissue gradually expands and replaces normal bone into fibro-osseous lesion. It is a primary developmental abnormality of bone-forming mesenchyme in origin. This study shows clinical history, radiological and histopathological feature of fibrous dysplasia with the intention of establishing correct diagnosis, treatment plan and evaluation of prognosis. This paper reviews and summarizes the materials from 57 fibrous dysplasias submitted to the Department of Oral and Maxillofacial Surgery in College of Dentistry, Seoul National University. Conclusions obtained were as following : 1. Fibrous dysplasia developed mainly in teenagers and shows female predeliction. 2. Fibrous dysplasia developed much on the maxilla 3. Monostotic fibrous dysplasia was most popular form. 4. Main symptom of fibrous dysplasia was painless swelling. 5. Radiological feature of fibrous dysplasia was ground-glass appearance, 6. Histopathological feature of fibrous dysplasia was irregular immature bony trabeculae(woven bone). 7. Treatment of fibrous dysplasia was mainly conservative contouring surgery.

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Expression Analysis of Schizophrenia Symptoms : Focusing on the Movies and (조현병 증상의 표현 분석 : 영화 <더 보이스>,<블랙 스완>을 중심으로)

  • Choi, Ji-Won
    • The Journal of the Korea Contents Association
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    • v.22 no.9
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    • pp.510-519
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    • 2022
  • This study aims to examine how delusions and hallucinations are expressed as representative symptoms of schizophrenia in the two films and . We look at how the two films show the appearance and overall image of the schizophrenic patient, the emotional expression of the schizophrenic patient, and how family and colleagues express the perceptions of the schizophrenic patient's symptoms. Finally, we will examine the perception of treatment measures for schizophrenia. Comprehensively, through this process, the schizophrenia symptoms expressed in the two films will have some effect on social perception of schizophrenia and the social implications of therapeutic intervention for schizophrenia recovery.