• Journal of Ginseng Research
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• v.30 no.1
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• pp.15-21
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• 2006

This study was carried out to determine the antioxidative activities of tissue cells of mouse kidney isolated from mice fed with different formulation of drinks. The swimming ability of experimental groups without caffeine showed the same pattern, but caffeine group decreased slightly. Superoxide dismutase(SOD) and catalase(CAT) activities of caffeine-containing groups were decreased significantly, but the control and ginseng-containing groups were increased. Hydroperoxide contents did not increase significantly all experimental groups. Hydroperoxlde contents of the control and ginseng-containing groups were similar, but caffeine-containing groups increased. Compared to the control and ginseng-containing groups, lipid peroxidation level and protein contents in caffeine-containing groups were decreased significantly. In conclusion, the antioxidative activities of mouse kidney isolated from mice fed with ginseng-containing products was increased slightly.

• The Journal of Korean Obstetrics and Gynecology
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• v.26 no.3
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• pp.1-17
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• 2013

Objectives: In this research, the effect of samul-tanggahyangbuja on depression and learning in ovariectomized rats subjected to repetitive stress were assessed. Samul-tanggahyangbuja is the prescription consisting of Samul-tang and Cyperi Rhizoma. Methods: Ovariectomized rats were repeatedly stressed over a 2-week period. After being orally medicated with samul-tanggahyangbuja (100 or 400 mg/kg), rats performed the Morris water maze test and forced swimming test, and social exploration was assessed in a behavior test. As well, sucrose intake was measured and measurements of blood serum corticosterone and the change of interleukin-$1{\beta}$ (IL-$1{\beta}$) and tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) in blood samples were made. Results: 1. In the Morris water maze test, rats medicated with 100 mg samul-tanggahyangbuja mastered the maze in a shorter time on the 4th day in comparison with the control group, while rats medicated with 400 mg samul-tanggahyangbuja mastered the maze more quickly (p<0.05 on the 3rd day ; p<0.01 on the 4th day, as compared to control). 2. Immobility time in the forced swimming test was significantly decreased in rats receiving 400 mg samul-tanggahyangbuja compared with the control group (p<0.05). 3. Sucrose intake and active social behavior of rats receiving 400 mg samul-tanggahyangbuja were markedly increased in comparison with the control group (p<0.01). 4. Blood serum corticosterone measurements revealed decreased blood serum corticosterone level after medicating with samul-tanggahyangbuja. But it was not statistically significant. 5. Treatment with either dose of samul-tanggahyangbuja significantly reduced IL-$1{\beta}$ and TNF-${\alpha}$ (p<0.05). Conclusions: These results suggest that samul-tanggahyangbuja possesses the anti-depressant and cognitive-enhancing activities related to menopause.

• Korean Journal of Ichthyology
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• v.21 no.3
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• pp.158-166
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• 2009

To obtain the fundamental data for the mass seedling production of grunt, Hapalogenys nitens, we investigated the influence of salinity and cold water temperature on hatching and survival of eggs and growth and survival of larvae and fry. In regards to salinity, we surveyed the hatching rate and floating rate of fertilized eggs, the floating rate and survival rate of hatching larvae, and the survival and growth of fry. In respect to cold temperature, we investigated the influence of degree of daily temperature decrease, acute temperature shock, and slow temperature decreases on the survival, feeding and swimming activities of fry. In the salinity experiment, the hatching and floating rates of fertilized eggs, and the floating and survival rates of hatching larvae, were shown to be higher in seawater than in brackish water. Growth and survival of larvae and fry were not different between seawater (25~32 psu) and brackish water (5~20 psu), but were significantly lower in freshwater. In the cold-temperature test, three tests showed that rearing of fry in cold water and acutely decreasing water temperature to less than $10^{\circ}C$ reduced the survival, feeding and swimming activities of the fry. Therefore, we concluded that low salinity (less than 32 psu) could reduce the hatching rate and survival of eggs, but the growth and survival of fry were not influenced by salinity, and cold water (less than $10^{\circ}C$) decreased metabolism of grunt. During winter, we found a low-temperature limit at $8^{\circ}C$.

• Korean Journal of Medicinal Crop Science
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• v.26 no.4
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• pp.271-280
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• 2018

Background: Astragalus membranaceus is a well known oriental medicinal herb. The polysaccharides of the aboveground parts (AMA) and the radix (AMR) of A. membranaceus are the most important functional constituents. Methods and Results: The aim of this study was to determine the effects of AMA and AMR on the oxidative damage induced in the skeletal muscle of rats subjected to exhaustive exercise. Sprague-Dawley rats were randomly divided into exercise and non-exercise groups; in the groups receiving the test compounds, AMA and AMR were administered orally for 30 days. Skeletal muscle samples were collected from each rat after running to exhaustion on a treadmill to determine the activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and catalase (CAT) and the concentation of malondialdehyde (MDA). The antioxidant enzyme activities of SOD and GSH-Px of skeletal muscle of AMA- and AMR-treated groups were significantly higher than those of the control and commercial sports drink (SPD)-treated groups in exhaustive exercise rats. In addition, MDA concentrations in the skeletal muscle of the AMA- and AMR-treated groups were significantly lower than those of the control and SPD-treated groups. In the present study, the effects of AMA and AMR on exercise endurance capacity were also evaluated in mice subjected to a swimming exercise test. AMA and AMR supplementation prolonged the swimming time of mice and enhanced exercise endurance capacity. AMA and AMR possess the ability to retard and lower the production of blood lactate, and prevent the decrease of serum blood glucose. Conclusions: These results showed that, AMR and AMA exerted beneficial effect in mice, increasing the activity of the antioxidant systems and inhibiting oxidative stress induced by exhaustive exercise. The compounds improved exercise performance and showed anti-fatigue effects against exhaustive exercise.

• Korean Journal of Food Science and Technology
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• v.34 no.4
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• pp.684-687
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• 2002

Water and methanol extracts of cricket were examined for their liver protective effects against $CCl_4-intoxication$ in ICR-mice. Serum transaminases (S-GOT and S-GPT), lactate dehydrogense (LDH) and glutathione-S-transferase (GST) activities and TBARS (Thiobarbiturate-reactive substances) content were measured for evaluation of liver protective effects. The activities of GOT, GPT, LDH and hepatic content of lipid peroxide after $CCl_4-treatment$ were higher than normal control but those levels decreased th 74, 50, 101 and 40%, respectively, by the treatment of cricket methanol extract. The anti-fatigue effects of water and methanol extracts investigated by an acute weight-loaded forced swimming test showed significantly prolonged swimming time in the mice administered cricket extracts. These results suggest us that water/alcohol extract of G. bimaculatus may be used as a liver protective food.

• Hwankyungkyoyuk
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• v.12 no.1
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• pp.189-204
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• 1999

Recently, the interest in artificial environment made by mankind as well as natural environment has been increased. This interest in the environment began to be reflected in the physical education, which environmental problems affect modern people's living quality as a crucial factor affecting directly or indirectly our life. Furthermore, since we entered the era of mass sports the physical education subject has dealt with destruction of natural environment by constructing golf courses, ski slopes, etc., destruction of ecosystem by water sports, mountaineering sports, aero sports, etc., and noise pollution near the sport facilities. Therefore, the purpose of this paper is to examine the means to reinforce environmental education in many ways in the physical education concerning environmental problems. For this purpose this paper analyzed the contents of the 7th curriculum for physical education which can be thought to be teaching materials for environmental education, and described the contents in detail. Also, this paper established the orientation and goals of environmental education in the physical education subject and examined some important teaching and learning methods. In addition, this paper suggested some considerations concerning environmental education and a textbook model for the development of physical education textbooks connecting with the 7th curriculum for physical education, which is to suggest a means to connect physical education with environmental education smoothly. The physical education has an attribute that its activities like swimming, climbing mountains, and camping are performed outdoor. The physical activities in the physical education are, of course, performed in the environment, so we had better implement the environmental education including such physical activities at the same time with physical education. Also, there should be efforts so that the education through environment, the education about environment, and the education in the environment can be implemented along with the physical education.

• Biomolecules & Therapeutics
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• v.24 no.3
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• pp.291-297
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• 2016

Cytisine (CYT), a partial agonist of ${\alpha}4{\beta}2-nicotinic$ receptors, has been used for antidepressant efficacy in several tests. Nicotinic receptors have been shown to be closely associated with depression. However, little is known about the effects of CYT on the depression. In the present study, a mouse model of depression, the unpredictable chronic mild stress (UCMS), was used to evaluate the activities of CYT. UCMS caused significant depression-like behaviors, as shown by the decrease of total distances in open field test, and the prolonged duration of immobility in tail suspension test and forced swimming test. Treatment with CYT for two weeks notably relieved the depression-like behaviors in the UCMS mice. Next, proteins related to depressive disorder in the brain region of hippocampus and amygdala were analyzed to elucidate the underlying mechanisms of CYT. CYT significantly reversed the decreases of 5-HT1A, BDNF, and mTOR levels in the hippocampus and amygdala. These results imply that CYT may act as a potential anti-depressant in the animals under chronic stress.

• The Journal of Korean Medicine
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• v.24 no.1
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• pp.84-91
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• 2003

Sasang Constitutional Medicine (SCM) is based on the theory of Sasang (Taeyang, Soyang, Taeum, Soeum) in Traditional Korean Medicine (TKM). It is hypothesized that all of the things in the material world can be divided into the four categories of SCM. We made a new attempt to combine nutritive components, and patterns in physical activities with SCM. At first, we hypothetically divided the nutrients into 4 compartments according to SCM theory, and human body composition as well. These factors could be basically related to Sasangin Exercise Treatment (SET). Therefore, we applied sasangin theory to exercise prescription. As a research method, we hypothesized that human beings' types can be distinguished by mind and body. Mind was focused on exercise psychological aspects, and body also handled by nutrients, body compositions, body shapes, and exercise physiological aspects. For application of sasang theory to the exercise prescriptions, Taeumin as a sample sasangin was selected in this study. We concluded that in perspective of general traits, Taeumin have to reduce their carbohydrate intake volume, but greatly increase their intake of vitamins, minerals, and water in daily diet. They are also recommended exercises that can increase cardiorespiratory function and make them sweat, like endurance running, hiking, swimming, cycling, etc.

• Journal of Fisheries and Marine Sciences Education
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• v.26 no.3
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• pp.567-577
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• 2014

The purpose of this research is to study in depth about the life, activities, and achievements of the swimming gold medalist in Asian Game, Cho O-Ryun, to make systematic correction. This research mainly used literary data to try making theoretical contemplation, and to raise objectivity and substantiality of literary research, and to be devoted to limited literary contents, it used acquaintances who are related to this research, especially his wife, Lee Sung-Lan. Cho O-Ryun's thoughts in physical education can be described as nationalistic physical educational thoughts. He did not only have pride as Korean, and tried to show superiority of our nation to the world, but he also tried very hard to prove that Dok-do Island is a Korean territory and not Japan's. He lived with water all his life, showed his everything as a proud Korean, worked as the most patriotic person of 20thcentury in Korea, and became to be a hero, dream, and hope to people in Korea. Spent all his sweat and energy to our country Korea, Cho O-Ryun, he was this era's true hero.

• YAKHAK HOEJI
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• v.51 no.6
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• pp.508-516
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• 2007

Thymus magnus is an endemic (Ulleung Island) species in Korea. This plant is used as diaphoretics and carminatives in traditional medicine. In the literature, few scientific assays were realized on this species, such as antibiotic (Streptococcus pneumoniae, Staphylococcus aureus, Salmonella enteritidis, and S. typhimurium) and antifungal activities. In order to clarify whether essential oil of T. magnus have pharmacological effects, anti-inflammatory, sedative, anti-depressant, analgesic, and sleep-prolonged effects were investigated using animal models. From this study, the following conclusions were attained; 1) Essential oil of T. magnus did not show any acute toxicity on mice when orally administered at the dose of 2-3 g/kg body weight. 2) Essential oil of T. magnus possessed strong anti-inflammatory activity, similar to that of a positive control prednisolone. 3) Essential oil of T. magnus had excellent analgesic activity, comparable to that of aspirin. 4) The essential oil of T. magnus possessed strong sleep-prolonged effect on pentobarbital induced-sleep test in mice model. 5) In the hot plate test, the essential oil of T. magnus had moderate effect. 6) And the essential oil of T. magnus had no significant effects in forced-swimming test and open-field test.