• Journal of Climate Change Research
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• v.6 no.3
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• pp.193-201
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• 2015

The aim of this study is to find preferred climate condition for outdoor water activity and to estimate future change of preferred season for the activity following the climate change. We chose urban public swimming pools, Hangang park swimming pools, which do not have any attractions except pools and allow people to make decision to visit pools in the morning solely based on the weather conditions as study sites. We identified the preferred climate conditions by analyzing the relationship between number of visitors and temperature, wind chill temperature and discomfort indexes. According to the result, the preferred temperature range was from $23.51^{\circ}C$ to $37.56^{\circ}C$, the wind chill temperature range was from $25.90^{\circ}C$ to $39.43^{\circ}C$, the discomfort index range was from 71.61 to 88.98 and the precipitation range was below 22.8 mm per day. When the temperature range is applied as the preferred season, in present, the length of the season is 127 days, from end of May to end of September. However, if temperature increase resulting from lower emission scenario (RCP 6.0), the season would be extended to 162 days, from early May to middle of October. If temperature is increasing under high emission scenario (RCP 8.5), the length of the season would be extended to 173 days from early May to end of October. In addition, the period of between end of July and early August, which is currently the most preferred season, would not be favored anymore due to high temperature. The result of this study further suggests the necessity of climate change adaptation activities.

• Bulletin of the Korean Chemical Society
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• v.31 no.2
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• pp.447-452
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• 2010

A series of 5-alkoxy-tetrazolo[1,5-a]quinolines were synthesized to evaluate their anticonvulsant and antidepressant effects. Anticonvulsant effects and neurotoxicity of the compounds when injected intraperitoneally to mice were determined by a maximal electroshock (MES) test and a rotarod test, respectively. Only three of the synthesized compounds (4a, 4b, 4c) displayed anticonvulsant activity at a dose of 300 mg/kg. Most of the compounds significantly reduced immobility times during the forced swimming test (FST) at a dose of 100 mg/kg, indicative of antidepressant activity. Among the compounds, 5-(2-fluorobenzyloxy)tetrazolo[1,5-a]quinoline (4k) reduced immobility time by 66.85% at 30 mg/kg compared with the same dose of Fluoxetine, which reduced immobility time by 52.30%. According to the results of the 5-Hydroxytryptophan induced head-twitch test and yohimbine toxicity potentiation test, the noradrenergic system seems not to be involved in the antidepressant-like effect of compound 4k while the serotonergic system seems a little to be involved.

• Korean Journal of Food Science and Technology
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• v.51 no.4
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• pp.398-403
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• 2019

Dioscorea japonica Thunberg (DJ) has been widely used as a healthy food in Korea for the enhancement of physical stamina. Hence, the present study evaluated the immune-enhancing effect of DJ in forced swim test of mouse model. The immobility time of the group treated with DJ for 7 days was significantly reduced in comparison with that of the control group. After a forced swimming test, the changes in blood biochemical parameters and splenic T lymphocyte populations induced by the administration of DJ were assessed. Serum levels of lactic dehydrogenase, creatine phosphokinase, and aspartate aminotransferase were significantly decreased in DJ-administered group compared to the control group. However, administration of DJ did not affect the splenic T lymphocyte populations. Moreover, DJ significantly increased the production of interferon-g and interleukin-2 compared to the media control in splenocytes. Collectively, it may be concluded that DJ is useful for enhancement of physical and immune function.

• Korean Journal of Pharmacognosy
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• v.31 no.2
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• pp.163-167
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• 2000

Cordyceps is reputed for its broad biological activities and as a tonic for replenishing vital function in Chinese traditional medicines. As an attempt to obtain fundamental data for the development of a new type Cordyceps, the effects of the fruiting bodies of cultivated fungus of Paecilomyces japonica grown on silkworm larvae on hyperglycemia induced by streptozotocin(STZ) and by epinephrine in rats and in mice as well as on immunological functions in mice were investigated. The 70% methanol extract of the fungus, when administered orally at 100 and 300 mg/kg in STZ-induced hyperglycemic rats, caused a significant decrease in blood glucose level 3hr after sample treatments. The methanol extract, when administered p.o. at the same dose levels in epinephrine-induced hyperglycemic mice, also caused a significant decrease in serum glucose levels as well as a significant reversal of the liver glycogen contents suggesting its hypoglycemic activity might be due to glycogen breakdown in the liver. Treatment of normoglycaemic mice with the methanol extract of the fungus exhibited a significant glucose tolerance up to 3hr after oral glucose load(2.0 g/kg). The methanol extract also showed immuno-stimulating activity as measured by carbon clearance in mice and a significant antifatigue effect as measured by weight loaded forced swimming performance in mice.

• The Korean Journal of Zoology
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• v.33 no.3
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• pp.297-302
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• 1990

The effects of ginseng saponin on the activity of serum alanine aminoiransferase (ALT) in trained rats were examined. The trained group was given a chronic swimming bout (approx. 90 min/day) for 50 days, and ginseng group was given an oral administration of ginseng saponin (150mg/kg/day) for 2 weeks. Ginseng treated-trained group was given an oral administration of ginseng saponin for 2 weeks prior to the termination of a swimming bout. In this experiment, male rats of Sprague-Dawley strain (250 $\pm$ 20 g) were used. The activities of serum ALT in trained and in ginseng groups increased 72.89% (P < 0.01) and 57.14% (P < 0.01) than in control groups, respectively. Also, the activities of serum ALT increased 69.66% (P <0.01) in saline treated-trained group, and 79.31% (P < 0.01) in ginseng treated-trained group than in control groups which were given saline solution and kept sedentary. The effect of ginseng saponin, as revealed by comparing the ginseng treated-trained group with the saline treated-trained group, was not significant. The present study suggests that training and ginseng saponin significantly increased the activity of serum ALT in rats, but that, in ginseng treated-trained group, ginseng saponin did not raise any further the increased activity of serum ALT by training.

• Journal of Families and Better Life
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• v.22 no.2
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• pp.97-107
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• 2004

The purposes of this study were compare the leisure attitudes, leisure activities, and leisure constraint among three different generations - teenagers, adults, and elderly adults. Data were obtained from a Questionnaire completed by both male and female lived metropolitan, and aged over 13. Using the factor analysis, this study classified the types of leisure attitudes. The leisure attitude was divided to 4 factors - reducing stress, self-realization, family activity, and surplus time. In order to compare the attitudes, activities, and constraints of leisure among three different generations, ANOVA was used The findings of this study are as follows: First, there were significant differences between teenager group and the others. The teenagers (n=107) recognized the leisure as a mechanism of reducing stress, or as just surplus time. They liked sports, computer games, travels, and reading books, but were not likely to like leisure activities shared with family members. Their leisure constraints were significantly larger than those of the other groups. Teenagers' constraints of time, money, and skills could be leisure barriers. Second, adults group (n=123) attached importance to the family leisure activities. They liked to spend time with their family members, but they seemed to be relatively passive in most types of leisure activities. They like to read newspapers and magazines, and to participate in religious activities. Third, elderly adults' (n=86) purpose of leisure activities was to improve the health condition, and to develop relationships with their friends. They liked sports such as swimming and aerobic dance, travels, religious activities and community service activities. Their good health condition and economic resources could decrease the leisure constraints.

• Journal of Preventive Medicine and Public Health
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• v.47 no.1
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• pp.27-35
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• 2014

Exposure factors based on the Korean population are required for making appropriate risk assessment. It is expected that handbooks for exposure factors will be applied in many fields, as well as by health department risk assessors. The present article describes the development of an exposure factors handbook that specifically focuses on human activities in situations involving the possible risk of exposure to environmental contaminants. We define majour exposure factors that represent behavioral patterns for risk assessment, including time spent on routine activities, in different places, on using transportation, and engaged in activities related to water contact including swimming, bathing and washing. Duration of residence and employment are also defined. National survey data were used to identify recommended levels of exposure factors in terms of time spent on routine activities and period of residence and employment. An online survey was conducted with 2073 subjects who were selected using a stratified random sampling method in order to develop a list of exposure factors for the time spent in different places and in performing water-related activities. We provide the statistical distribution of the variables, and report reference levels of average exposure based on the reliable data in our exposure factors handbook.

• Biomolecules & Therapeutics
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• v.15 no.1
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• pp.27-33
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• 2007

The psychopharmacological profile of ginsenosides has not yet been confirmed systematically although various neuropharmacological activities associated with them have been investigated. In the present study, the psychological activities of Rb1 were investigated to evaluate whether it can be used in treatment or prevention of psychological disorders. Rb1 was intravenously injected at doses of O.2,2,5 and 10 mg/kg. The effects of Rb1 on the $Cl^-$ ion influx were investigated using IMR-32 human neuroblastoma cells. Moreover, locomotor activity, forced swimming activity, activity on rotating rod and activity in elevated plus-maze were tested in mice. Rb1 increased the $Cl^-$ influx into the intracell region in a dose-dependent manner. Rb1 did not cause change in behavior in total open field when locomotor activity was tested, however it increased activities, especially, such as rearing frequency in center area. Administration of Rb1 at 0.2 mg/kg significantly reduced activities on rotating rod however administration at high dosages had no effect on them. Rb1 administration decreased animal immobile time in a water chamber in a dose dependent manner, and increased the strong mobile time of animals. In conclusion, the present results demonstrate that Rb1 contributes to the psychopharmacological effects of ginseng and may be used in treatment or prevention of psychological disorders such as anxiety or depression.

• Korean Journal of Medicinal Crop Science
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• v.13 no.2
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• pp.103-109
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• 2005

When we carried out an anti-stress study using the extracts of A. senticosus, R. coreanus, F .japonica root, and A. fruticosa fruit grown in Korea, the results showed that blood cell counts returned to normal levels fastest with R. coreanus after stress application. The total WBC count was decreased in mice due to stress, whereas the number of lymphocytes was increased. The serum glucose level was higher in the control group compared with the comparative stress group. The weight of each organ to returning to normal level was significantly faster in those mice treated with the extracts compared with those in control groups. Especially, it even return to that of normal level with R. coreanus extract, suggesting that the administration of the plant extracts in this study would affect hormonal activities in the body to increase immune activities. F. japonica root that showed the highest anti-stress activities maybe effective for lipid and carbohydrate metabolism. These results would provide basic data to examine anti-stress effects of natural plants. Further in-depth studies could contribute in the development of functional plant materials with anti-stress activities.

• Journal of the Korean housing association
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• v.26 no.6
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• pp.199-206
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• 2015

The purpose of this study was to identify services and programs that will be needed for helping senior residents to be aging healthfully and comfortably in the university-based retirement community (UBRC). This study conducted a questionnaire survey targeting about 900 faculty and staff members in one of national universities. A total of 214 valid responses were analyzed for identifying necessary services and programs. The study also analyzed the differences in resident's opinions depending on their intention to live in the UBRC. Over 65% of the respondents were willing to live in the UBRC. The most desirable services were healthcare services including emergency care and nursing care and cleaning and laundry services. Regarding the educational and recreational programs, future residents chose physical exercises such as swimming and tennis and music activities such as playing instruments and singing as the most interesting programs they want to experience in UBRC. Most of the respondents were interested in mentoring college students or international students who come to the university for their degrees. The findings from the study should provide a guideline when offering services, programs, and activities in the future UBRC in Korea.