• Title/Summary/Keyword: Survival Rates

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항암제와 Lactobacillus casei HY2782의 병용투여에 의한 항암효과의 증강 (Augmentation of antitumor activity of antitumor drugs in combination with Lactobacillus casei HY2782)

  • 윤상군;배형석;김경태;백영진
    • 한국미생물·생명공학회지
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    • 제24권1호
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    • pp.37-43
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    • 1996
  • Augmentation of antitumor activity of antitumor drugs in combination with Lactobacillus casei HY2782 (LC2782) was studied against Sarcoma-180 (S-180) and Lewis lung carcinoma (3LL). Antitumor drugs used in this study were 5-fluorouracil (5-fu) and cyclophosphamide (CP). The prolongation effect of LC2872 on the life span of mouse intraperitoneally implanted with S-180 was stronger than that of OK-432 and BCG, while the inhibitory effect of OK-432 and BCG on the growth of 3LL solid tumor was a little stronger than that of LC2782. Average survival rates of mice administrated LC2782, OK-432 and BCG were 192%, 141%, and 112%, respectively, when that of the control was 100%, Intralesional administration of 5-Fu, CP, 5-Fu+LC2782 and CP+LC2782 resulted in 93%, 69%, 99% and 73% inhibition rates against 3LL solid tumor proliferation. The combination therapy of 5-Fu or CP with LC2782 significantly prolonged the life span of S-180-inoculated ICR mice. Average survival rates of mice administrated 5-Fu and CP alone were 115% and 99%. Furthermore, survival rates of mice administrated 5-Fu and CP in combination with LC2782 were 226% and 244%, respectively.

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바지락 발생배의 냉동보존에 관한 보존액의 효과 (Effect of Cryoprotectants on the Cryopreservation of Manila Clam, Ruditapes philippinarum Embryo)

  • 강경호
    • 융합정보논문지
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    • 제11권1호
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    • pp.128-135
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    • 2021
  • 바지락 발생배의 냉동보존을 위한 동해방지제의 효과를 규명하기 위하여4종의 보존액, dimethyl sulfoxide, ethylene glycol, glycerol 및 1,2-propanediol을 사용하여 발생배의 생존율을 조사한 결과로, 생존율의 범위는 0-64.3%였고, 대조구의 생존율은 82.3%을 보였다. 발생배의 냉동보존을 위한 프로그래 동결 과정은 최초 25℃에서 10분 동안 유지하다가 자동 냉동보존 프로그램 장치에 의하여 -12℃까지 분당 -1℃씩 조정하였으며 -35℃까지는 분당 -2℃씩 하강시켜 액체 질소통에 스트로우를 넣어 해동 후 관찰한 결과, 바지락 생존율은 DMSO(dimethyl sulfoxide) 2.0M 실험구에서 64.3%로 가장 좋은 결과를 보였다.

장막 침윤이 없는 위암 환자에서 수술 후 보조적 화학 요법에 대한 전향적 연구 -중간 보고- (Prospective Randomized Trial for Postoperative Adjuvant Chemotherapy in Gastric Cancer Patients without Serosal Invasion -Preliminary Report-)

  • 김용호;김병식;이창환;김완수;육정환;오성태;박건춘
    • Journal of Gastric Cancer
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    • 제1권4호
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    • pp.221-227
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    • 2001
  • Purpose: We have carried out prospective randomized clinical trial to compare survival benefit and side effect among three postoperative adjuvant chemotherapeutic regimens in serosa-negative gastric cancer patients. Materials and Methods: Total 317 cases were recognized as serosa negative and randomized into three groups at operating room. Out of them, 172 cases were excluded because of various reasons and 135 cases were analyzed finally; Group A 36 cases, Group B 49 cases, Group C 50 cases. Group A were treated with intravenous FP combination therapy, group B with MF combination therapy and group C with oral $UFT^{(R)}$ (mixture of Tegafur and Uracil) for one year. The median follow-up period was 30 months. Results: $88.9\%$ of Group A, $83.7\%$ of Group B and $90.4\%$ of Group C received adequate chemotherapy. The complication rates of Group A ($44.4\%$) was significantly higher than group B ($20.4\%$) and group C ($24.0\%$)(P<0.05). Most frequent complications were nausea and vomiting. The 3-year survival rates and disease-free survival rates were $92.2\%$ and $89.9\%$ respectively (Group A: $96.6\%,\;87.8\%$, B: $90.3\%,\;87.7\%$, C: $95.7\%,\;93.8\%$). There were no significant differences in survival rate and disease-free survival rate among the three groups (P>0.05). Conclusion: This study might suggest that the survival benefit of postoperative adjuvant chemotherapy for gastric Pseudomonas aeruginosa, and therefore it may be a useful adjunct tool for detection of Pseudomonas aeruginosa infection in combination with other conventional techniques.

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RBM 표면 임플란트와 산부식 표면 임플란트의 3년 생존율에 대한 비교 연구 (3-Year Survival Analysis of RBM and Acid-Etched Surface Implants)

  • 윤대웅;김문섭;장한성;진수영;마득현;정경달;박현춘;김희중;김학균
    • 구강회복응용과학지
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    • 제27권4호
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    • pp.393-403
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    • 2011
  • 이 연구의 목적은 임상적으로 사용되는 RBM과 산부식 임플란트의 3년 생존율을 비교, 분석하기 위한 것이다. 총 152개의 RBM 임플란트를 식립하였고, 이 중 1개의 임플란트에서 실패가 발생하였는데, 원인은 식립체의 파절이었다. 또한 총 152개의 산부식 표면 임플란트를 식립하였는데, 이 중 7개의 임플란트에서 실패를 하였으며, 원인으로는 과열, 감염, 초기고정 불량 등이었다. RBM 임플란트의 생존율은 99.34%, 산부식 임플란트의 생존율은 95.39%로 두 가지 임플란트 모두 양호한 생존율을 보였으나, RBM 임플란트에서 다소 높은 생존율을 나타내었다.

소 수정란의 할구 분리방법에 따른 생존율 및 성판별 PCR의 개선 (The Improvement of Sexing PCR Conditions and Survival Rate of Blastomere Separation Method in the Bovine Embryo)

  • 김상환;김경래;이호준;;;정덕원;김대은;이득환;윤종택
    • 한국수정란이식학회지
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    • 제28권3호
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    • pp.199-205
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    • 2013
  • The present study was conducted to compare on embryo survival rates by blastomere isolation methods, and establish the optimal PCR procedure for perform the sexing of bovine blastocysts produced by IVF. IVF embryos used in the study was used the Bisected or Sliced methods for blastomere isolation, and the survival rates of blastocyst with rapid way of sexing PCR was assessed. In the present study for survival rates in blastocyst was the total cleavage rate was 75% and a blastocyst development among cleaved embryos was 40%. Survival rate of embryos treated with intact, bisected or sliced method was 100, 63.3 or 81.3%, respectively. Therefore, survival rate of embryos treated with sliced method was higher compared to that of embryos treated with bisected method. The sexing rate of female or male was not significantly different between S4BFBR primer and BSY + BSP primer (1.75 : 1 vs. 1.43 : 1), respectively. Because of the PCR amplification using the S4BFBR primer was simpler method than multiplex PCR amplification method. Furthermore, the accuracy of sexing rate and reduction of PCR work time between 2-step and 3-step of PCR methods was 98.0% / 1.5 hr and 97.0% / 3.5 hr, respectively. Based on these results, it can be suggested that the sliced and PCR methods we developed was very effective method to reduce time consuming and procedure of PCR amplification for sexing with the increase of survival rate on the blastocyst.

출혈성 쇼크를 일으킨 흰쥐에서 로지스틱 회귀분석을 이용한 생존율 예측 (A survival prediction model of hemorrhagic shock in rats using a logistic regression equation)

  • 이탁형;이주형;정상원;김덕원
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2009년도 정보 및 제어 심포지움 논문집
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    • pp.132-134
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    • 2009
  • Hemorrhagic shock is a common cause of death in emergency rooms. Since the symptoms of hemorrhagic shock occur after shock has considerably progressed, it is difficult to diagnose shock early. The purpose of this study was to improve early diagnosis of hemorrhagic shock using a survival prediction model in rats. We measured ECG, blood pressure, respiration and temperature in 45 Sprague-Dawley rats, and then obtained a logistic regression equation predicting survival rates. Area under the ROC curves was 0.99. The Hosmer-Lemeshow goodness-of-fit chi-square was 0.86(degree of freedom=8, p=0.999). Applying the determined optimal boundary value of 0.25, the accuracy of survival prediction was 94.7%

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The Relationship between Vegetation Cover and Hatching Success, and Chicks' Survival in Black-Tailed Gulls on Hongdo Island

  • Lee, Who-Seung;Kwon, Young-Soo;Yoo, Jeong-Chil
    • Journal of Ecology and Environment
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    • 제29권1호
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    • pp.35-39
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    • 2006
  • During the breeding seasons in 2002 and 2003, the influences of vegetation cover on breeding processes of Black-tailed Gulls (Laurs crassirostris) were studied on Hongdo Island. We checked dutch sizes, calculated hatching success and survival rates on day 15 and a vegetation cover, There was significant positive relationship between vegetation cover and hatching success, and survival on day 15. In order to analyze the relationship, sample nests were categorized as 'exposed' and 'covered' nests, and the breeding processes at each nest were compared. Hatching success and survival on day 15 in covered nests were significantly higher than ones in exposed nests. However, in clutch size, there was no significant difference. The rate of the hatching and survival failure was different amongst the categorized nests. The primary cause of hatching failure in covered and exposed nests was 'disappeared', and the primary causes of survival failure on day 15 were 'disappeared' and 'killed by adults'. The failure in exposed nests was significantly larger than that of covered nests. In the breeding of Black-tailed Gulls on Hongdo Island, vegetation cover influenced the survival of eggs and chicks as the cover provided shelter against predators and extreme weather.

Reproduction rate and stolon production rate after transplantation of grass germplasm

  • Jung, Ji Hyeon;Han, Gyung Deok;Kim, Jaeyoung;Chung, Yong Suk
    • 농업과학연구
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    • 제48권3호
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    • pp.465-471
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    • 2021
  • Grass breeding starts with the process of selecting grass with good traits, and this operation consumes a lot of resources. Therefore, there is a need for an efficient screening method. Stolon is a unit for the storage of carbohydrates and vegetative propagation, which enhances grass growth and grass sod. Grass varieties with active production of stolons have excellent traits because they reproduce quickly and have a high density. To select grass with such a trait, the survival rate and the production rate of stolon after transplantation of 72 grass germplasms were investigated. After transplantation, the survival rate ranged from 75% to 100%. The majority of the grass cultivars showed a 100% survival rate. Therefore, the group was divided into two groups: A grass variety showing 100% survival and a grass variety that did not show 100% survival. The grass cultivar group, which showed a 100% survival rate after transplantation, included 61 turf varieties, and the rates of stolon production in these grass varieties ranged from 0 to 100%. In contrast, 10 varieties were included in the grass cultivar group that did not show 100% survival after transplantation. These cultivars had a stolon production rate of 0 to 33%. The results suggest that grass germplasms with a 100% survival rate should be selected.

생존기간을 고려한 생애소득대체율의 추정 (The estimation of lifetime income replacement rates)

  • 신승희;손현섭;이항석
    • Journal of the Korean Data and Information Science Society
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    • 제25권6호
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    • pp.1315-1331
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    • 2014
  • 소득대체율은 은퇴 전 소득 대비 은퇴 후 소득이 어느 정도 인지를 나타내는 지표로써, 사회보장제도의 급여수준이나 노후대비소득의 적정성을 논할 때 매우 유용하게 사용된다. 기존 연구들은 소득대체율 개념을 통해 은퇴시점이나 특정 은퇴기간의 은퇴소득을 진단하고 있다. 본 연구에서는 생애에 초점을 두고 생존기간에 따라 소득대체율이 어떻게 변화하는지 살펴보았으며, 생존기간에 따른 소득대체율을 하나의 지표 값으로 나타내어 분석하였다. 이를 생애소득대체율로 명명하였으며, 분석결과 3대 연금에 모두 20년 가입 시 남자의 생애소득대체율은 38.3%, 여자의 생애소득대체율은 41.1%로 예상된다.

난대상록활엽수종 조림지 활착률과 영향인자 (The Characteristics and Survival Rates of Evergreen Broad-Leaved Tree Plantations in Korea)

  • 박준형;정수영;이광수;이호상
    • 한국산림과학회지
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    • 제108권4호
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    • pp.513-521
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    • 2019
  • 본 연구는 전국 난대상록활엽수종의 조림지에 대한 생육환경 및 입지환경 특성과 활착률간의 관계특성으로부터 조림적지 의사결정 기초자료를 제공하고자 하였다. 1997년부터 후박나무(Machilus thunbergii), 구실잣밤나무(Castanopsis sieboldii) 등 난대상록활엽수 10종의 신규 조림지 180ha의 148개 조사구에 대한 활착률을 모니터링 한 결과 평균 활착률은 67.0±26.9%이었다. 활착률 편차가 크게 나타난 원인은 조림 적지에 관한 실증적 현지 검증이 부족한 상황에서 다양한 입지를 대상으로 시험 조림이 이루어진 결과로 판단된다. 각 조사구별 11개 생육환경 및 입지환경 특성, 조림전후 강수 등의 정성적 설명요인과 활착률의 정량적 요인 간의 관계특성으로부터 수량화 이론 I에 따른 활착률에 대한 기여도를 분석한 결과, 조림지 상층임분 울폐도, 풍노출도, 조림 전 누적 강수량, 경사도 등의 순으로 높게 나타났다.