• Computers and Concrete
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• 제24권4호
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• pp.329-345
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• 2019

Despite the extensive use of mortar materials in constructions over the last decades, there is not yet a robust quantitative method, available in the literature, which can reliably predict mortar strength based on its mix components. This limitation is due to the highly nonlinear relation between the mortar's compressive strength and the mixed components. In this paper, the application of artificial neural networks for predicting the compressive strength of mortars has been investigated. Specifically, surrogate models (such as artificial neural network models) have been used for the prediction of the compressive strength of mortars (based on experimental data available in the literature). Furthermore, compressive strength maps are presented for the first time, aiming to facilitate mortar mix design. The comparison of the derived results with the experimental findings demonstrates the ability of artificial neural networks to approximate the compressive strength of mortars in a reliable and robust manner.

• ETRI Journal
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• 제44권5호
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• pp.805-815
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• 2022

The model-based evolutionary algorithms are divided into three groups: estimation of distribution algorithms, inverse modeling, and surrogate modeling. Existing inverse modeling is mainly applied to solve multi-objective optimization problems and is not suitable for many-objective optimization problems. Some inversed-model techniques, such as the inversed-model of multi-objective evolutionary algorithm, constructed from the Pareto front (PF) to the Pareto solution on nondominated solutions using a random grouping method and Gaussian process, were introduced. However, some of the most efficient inverse models might be eliminated during this procedure. Also, there are challenges, such as the presence of many local PFs and developing poor solutions when the population has no evident regularity. This paper proposes inverse modeling using random forest regression and uniform reference points that map all nondominated solutions from the objective space to the decision space to solve many-objective optimization problems. The proposed algorithm is evaluated using the benchmark test suite for evolutionary algorithms. The results show an improvement in diversity and convergence performance (quality indicators).

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2004년도 Proceedings of the 4th Korea-China Joint Workshop on Nuclear Waste Management
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• pp.165-169
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• 2004

It was studied on the reductive extraction between the eutectic salt and Bi metal phases. The solutes were zirconium and the rare earth elements, where zirconium was used as the surrogate for the transuranic(TRU) elements. All the experiments were performed in a glove box filled with argon gas. Two types of experimental conditions were used -high and low initial solute concentrations in salt. Li-Bi alloy was used as a reducing agent to reduce the high chemical activity of Li. The reductive extraction characteristics were examined using ICP, XRD and EPMA analysis. Zirconium was successfully separated from the rare earth elements by the reductive extraction method. The LiF-NaF-KF system was favorable among the fluoride salt systems, whereas the LiCl-KCl system was favorable among the chloride salt systems. When the solute concentrations were high, intermetallic compounds were found near the salt-metal interface.

• 신재생에너지
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• 제20권1호
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• pp.79-87
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• 2024

This study introduces a method for estimating Aerosol Optical Depth (AOD) using Broadband Aerosol Optical Depth (BAOD) derived from direct normal irradiance and meteorological factors observed between 2016 and 2017. Through correlation analyses between BAOD and atmospheric components such as Rayleigh scattering, water vapor, and tropospheric nitrogen dioxide, significant relationships were identified, enabling accurate AOD estimation. The methodology demonstrated high correlation coefficients and low Root Mean Square Errors (RMSE) compared to actual AOD₅₀₀ measurements, indicating that the attenuation effects of water vapor and the direct impact of tropospheric nitrogen dioxide concentration are crucial for precise aerosol optical depth estimation. The application of BAOD for estimating AOD₅₀₀ across various time scales-hourly, daily, and monthly-showed the approach's robustness in understanding aerosol distributions and their optical properties, with a high coefficient of determination (0.96) for monthly average AOD₅₀₀ estimates. This study simplifies the aerosol monitoring process and enhances the accuracy and reliability of AOD estimations, offering valuable insights into aerosol research and its implications for climate modeling and air quality assessment. The findings underscore the viability of using BAOD as a surrogate for direct AOD₅₀₀ measurements, presenting a promising avenue for more accessible and accurate aerosol monitoring practices, crucial for improving our understanding of aerosol dynamics and their environmental impacts.

• Journal of Animal Science and Technology
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• 제66권1호
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• pp.156-166
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• 2024

Pigs are genetically, anatomically, and physiologically similar to humans. Recently, pigs are in the spotlight as a suitable source animal for xenotransplantation. However, to use pigs as source animals, pigs should be raised in designated pathogen-free facilities. There is abundant data from embryo transfer (ET) experiments using farm pigs as surrogates, but data on ET experiments using minipigs are scarce. Eighty minipigs were used for ET experiments and after transplantation, the implantation and delivery rates were investigated. It was also confirmed whether the pregnancy rate could be increased by changing the condition or surgical method of the surrogate. In the case of minipigs that gave birth, the size of the fetal sac on the 28th day of ET was also measured. The factors that can affect the pregnancy rate such as estrus synchronization program, ovulation status at the time of ET, the number of repeated ET surgeries, and the ET sites, were changed, and the differences on the pregnancy rate were observed. However there were no significant differences in pregnancy rate in minipigs. The diameter of the implanted fetal sac on the 28th day after ET in the minipigs whose delivery was confirmed was calculated to be 4.7 ± 0.5 cm. In conclusion, there were no significant differences in pregnancy rate of minipigs in the comparative experiment on various factors affecting the pregnancy rate. However, additional experiments and analyses are needed due to the large individual differences of the minipigs.

• The Korean Journal of Physiology and Pharmacology
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• 제15권2호
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• pp.67-81
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• 2011

Epilepsy is a chronic disease occurring in approximately 1.0% of the world's population. About 30% of the epileptic patients treated with availably antiepileptic drugs (AEDs) continue to have seizures and are considered therapy-resistant or refractory patients. The ultimate goal for the use of AEDs is complete cessation of seizures without side effects. Because of a narrow therapeutic index of AEDs, a complete understanding of its clinical pharmacokinetics is essential for understanding of the pharmacodynamics of these drugs. These drug concentrations in biological fluids serve as surrogate markers and can be used to guide or target drug dosing. Because early studies demonstrated clinical and/or electroencephalographic correlations with serum concentrations of several AEDs, It has been almost 50 years since clinicians started using plasma concentrations of AEDs to optimize pharmacotherapy in patients with epilepsy. Therefore, validated analytical method for concentrations of AEDs in biological fluids is a necessity in order to explore pharmacokinetics, bioequivalence and TDM in various clinical situations. There are hundreds of published articles on the analysis of specific AEDs by a wide variety of analytical methods in biological samples have appears over the past decade. This review intends to provide an updated, concise overview on the modern method development for monitoring AEDs for pharmacokinetic studies, bioequivalence and therapeutic drug monitoring.

• 융합보안논문지
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• 제15권7호
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• pp.75-84
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• 2015

윈도우즈 NTFS 파일시스템에서 인덱스 레코드에 데이터를 숨기기 위한 기법은 파일명을 이용하여 메시지를 숨기는 방법이다. 윈도우즈 NTFS의 파일명 규칙에서 일부 ASCII 문자는 파일명으로 사용할 수 없는 문제가 있다. 영문과 함께 한글, 기호 문자가 함께 입력이 될 때와 바이너리 형태의 데이터들이 입력될 때 인덱스 레코드에 데이터 숨기기 방법 수행 시에 파일생성 에러 문제가 발생하는 것을 해결하기 위한 방법으로 유니코드의 특정 영역으로 변환하는 방법을 제안한다. 에러가 발생하는 문자들을 한글과 영문 영역이 아닌 유니코드로 변환하고. 바이너리 형태의 데이터인 경우는 확장 유니코드 영역과 아스키 코드의 영역이 아닌 유니코드의 영역으로 256개의 코드 전체를 변환하는 방식을 적용한다. 영문과 함께 한글이 사용된 경우에 제안한 방식이 적용된 사례의 결과를 보이고. 바이너리의 경우는 PNG이미지 파일의 바이너리 코드를 유니코드로 변환한 사례를 통해서 제안한 방법이 타당함을 보인다.

• Asia pacific journal of information systems
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• 제4권2호
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• pp.247-263
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• 1994

This paper reports the results of a field study investigating the effect of user participation and attitude on the success of information system implementation during the system development process. The theoretical framework for this research is based on the organizational change theory, in which the attitude affects the effects of user's participation. User participation and attitude were defined as independent variables and the performance of system implementation as dependent variable. User participation was defined as a direct participation by end users in the process of the new information system development. This was measured by user's participation/non-participation. User attitude refers to user's opinions or feelings before a new system is developed. This was measured by user's favor toward a system. The performance of system implementation was measured by the surrogate variable, the degree of individual satisfaction on developed system. To achieve the objective of this research, a field research method utilizing questionnaires were employed. They were distributed to 221 users present during and/or after system development. Among 185 questionnaires returned, 175 questionnaires were used for analysis. The major findings can be summarized as follows: First, there was no significant effect of user participation on user satisfaction. Second, there was a significant effect of user attitude on user satisfaction. Third, there was no significant interaction effect of user participation and attitude on user satisfaction. It is worth to note that the user's participation did not have any significant effect on the user's satisfaction. It seems the reason for the above result is due to user's involuntary participation. In fact, the user does not have much leverage in the process of system development, which may result in poor performance of user participation. Since user attitude is an important factor in the success of system implementation, however, a method to overcome unfavorable attitude of user should proceed all others.

• 한국산업보건학회지
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• 제18권2호
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• pp.99-107
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• 2008

We quantified the human carcinogenic metals (chromium, nickel) in fumes from flux cored arc welding using stainless steel (FCAW/SS) wires. Zinc and calcium were also quantified because of their possibility of zinc chromate and calcium chromate, respectively. Welding was performed in an American Welding Society standard fume collection chamber. Insoluble and soluble forms of metals were analyzed by ISO 15202 method. Total chromium (insoluble+soluble) content and total nickel content were lower in FCAW/SS fumes (4.65%, 1.05%, respectively)than in stainless steel content (ca. 18%, 8%,respectively). Insoluble fraction in total chromium was 79.8 (range 64.5~95.1)% and 94.4(range 90.1~98.1)% in total nickel. Atomic emission spectroscopy used in this study does not differentiate the chromium valence status while ACGIH defines its carcinogenicity according to the valence status. From this study and previous study, we estimated the hexavalent chromium content in FCAW/SS was 0.2~1.1% and about 85% of them was soluble. The content of zinc and calcium, which can be existed as chromate forms, was low (0.02 %, 0.04% respectively) in FCAW/SS. Exposure assessment for zinc chromate and calcium chromate is possible because chromium in both compounds is used as a surrogate even though it is not well known that what compounds of zinc and calcium are formed in welding fume.

• Radiation Oncology Journal
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• 제30권2호
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• pp.70-77
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• 2012

Purpose: To evaluate the patterns of tumor shape and to compare tumor volume derived from simple diameter-based ellipsoid measurement with that derived from tracing the entire tumor contour using region of interest (ROI)-based 3D volumetry with respect to the prediction outcome in cervical cancer patients treated with concurrent chemotherapy and radiotherapy. Materials and Methods: Magnetic resonance imaging was performed in 98 patients with cervical cancer (stage IB-IIIB). The tumor shape was classified into two categories: ellipsoid and non-ellipsoid shape. ROI-based volumetry was derived from each magnetic resonance slice on the work station. For the diameter-based surrogate "ellipsoid volume," the three orthogonal diameters were measured to calculate volume as an ellipsoid. Results: The more than half of tumor (55.1%) had a non-ellipsoid configuration. The predictions for outcome were consistent between two volume groups, with overall survival of 93.6% and 87.7% for small tumor (<20 mL), 62.9% and 69.1% for intermediate-size tumor (20-39 mL), and 14.5% and 16.7% for large tumors (${\geq}$40 mL) using ROI and diameter based measurement, respectively. Disease-free survival was 93.8% and 90.6% for small tumor, 54.3% and 62.7% for intermediate-size tumor, and 13.7% and 10.3% for large tumor using ROI and diameter based method, respectively. Differences in outcome between size groups were statistically significant, and the differences in outcome predicted by the tumor volume by two different methods. Conclusion: Our data suggested that large numbers of cervical cancers are not ellipsoid. However, simple diameter-based tumor volume measurement appears to be useful in comparison with ROI-based volumetry for predicting outcome in cervical cancer patients.