• Journal of Chest Surgery
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• 제36권6호
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• pp.379-383
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• 2003

배경: 장기 심장 이식 후에 나타나는 거부반응의 정도와 상태에 대한 정확한 진단은 내심근 조직검사 (endomyocardial biopsy)로 이루어지고 있으나, 이 방법은 환자에 침습적이고 보다 자주 시행하여 감시하기에는 부적합하여, 덜 침습적이고 계속 지속적으로 감시할 수 있는 방법을 찾고자 하였다. 대상 및 방법: 250~300 gm 정도의 백서에서 이소성의 심장이식(heterotopic heart transplantation)을 Ono-Lindsey Method로 시행한 후 1개월 후에 $^{99m}$ Tc-pyrophosphate (PYP) 1.5 mCi를 꼬리 정맥을 통해 주입한 후 스캔(scan)을 시행하고 심장과 척추의 섭취비를 구하여 이식된 심장의 거부반응에 민감하게 반응할 수 있을 지에 대해 조직 검사와 비교관찰 하였다. 걸과: 20마리의 이식된 심장에 $^{99m}$ Tc-PYP스캔에서의 심장/척추 섭취비와 조직 검사 결과를 분석하여 심장/척추 섭취비가 0.09 이상을 거부반응이 있는 것으로 판정하였을 때 20마리에서 진양성 3예, 진음성 12예, 가양성 3예, 가음성 2예로 예민도 (Sensitivity) 60%,특이도(Specificity) 80%의 결과를 얻었다. 걸론: 이식된 장기의 거부반응이 장기이식의 예후에 미치는 중요한 원인이 되므로, 이에 대한 조기 진단할 수 있는 방법으로 $^{99m}$ Tc-PYP스캔이 유용하였으며, 비침습적이고 간단한 검사방법이므로 거부반응 여부를 감시하는 데 도움이 될 것으로 판단된다.

• Archives of Plastic Surgery
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• 제36권3호
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• pp.262-268
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• 2009

Purpose: Recently medical dispute about plastic surgery is increasing rapidly as result of growing surgery itself due to high interest in appearance and advertisement of plastic surgery. So we want to find a way to prevent similar medical accident by making better solution of plastic surgery through case analysis of medical dispute. Method: 161 cases about plastic surgery asked for aid at Korea Consumer Agency and 41 cases judged at the court was surveyed and gender, location and kind of hospital, goal and kind of operation, making operation agreement or not, kind of damage, result of process, result of lawsuit was studied from 2004.1.1. to 2006.12.31. Result: Medical doctor have to explain about symptoms of disease, method of treatment, possibility of complication, prognosis to patients before therapy so they can make decision if they take operation by doctor or not. On this survey, among the patients who underwent re - operation or had complication, 88.1%(96 from 109 cases) of them didn't get enough explanation about possibility of complication before surgery They brought lawsuit insisting they would not undergo operation if they got enough explanation about possibility of complication and result of operation before surgery. Conclusion: It is advisable that doctor must observe the duty of explanation before surgery and respect the right to decide of patient, make operation agreement and put down concrete progress note and store the pre and post operative photo to avoid medical accident. It is also needed to have guideline of therapy, Code of ethics, organization which deals with medical dispute, reconsideration of law to control that.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제17권1호
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• pp.1-9
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• 1995

1986년 1월부터 1993년 12월까지 8년간 외과적 교정술을 시행한 117 증례에대하여 임상적인 관찰을 시행하였다. 1) 남녀 성비는 1:1.4로 여자가 많았으며 평균연령은 23.0세였다. 2) 악교정수술을 받기위하여 내원한 환자의 진단에 따른 분류를 보면 하악 전들증의 경우가 87증례(75.0%)로 주종을 이루고 있었다. 3) 수술방법중 하악단독수술은 88증례, 상악골 단독수술은 6증례, 상하악 동시이동술은 23증례였으며 이중 하악지 시상골절단술이 사용된 경우가 84증례(71.8%)로 가장 많았다. 4) 골편의 고정을 위하여 강선고정보다 Miniplate나 Screw 를 이용한 고정이 점차 선호되고 있으며 전체수술에서 견고고정의 비율은 66.0%였다. 5) 본 교실에서는 외가적 교정수술 환자를 대상으로 1992년 2월부터 저혈식 자가수혈을 이용하고 있으며 One Jaw surgery 에서는 2 pints, Two Jaw surgery 에서는 3 pints를 준비하고 잇다. 6) 악교정수술의 합병증으로는 하순지각마비등의 신경손상이 전체수술의 63증례(53.8%)로 가장 많았으며 골편의 잘못된 위치, 과두위치보존의 실패, 견고고정의 불안정등이 원인이 되어 5증례에서 재수술을 시행하였다.

• Archives of Plastic Surgery
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• 제43권5호
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• pp.424-429
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• 2016

Background The objective of this paper was to describe a novel technique for improving the maintenance of nipple projection in primary nipple reconstruction by using acellular dermal matrix as a strut in one of three different configurations, according to the method of prior breast reconstruction. The struts were designed to best fill the different types of dead spaces in nipple reconstruction depending on the breast reconstruction method. Methods A total of 50 primary nipple reconstructions were performed between May 2012 and May 2015. The prior breast reconstruction methods were latissimus dorsi (LD) flap (28 cases), transverse rectus abdominis myocutaneous (TRAM) flap (10 cases), or tissue expander/implant (12 cases). The nipple reconstruction technique involved the use of local flaps, including the C-V flap or star flap. A $1{\times}2-cm$ acellular dermal matrix was placed into the core with O-, I-, and L-shaped struts for prior LD, TRAM, and expander/implant methods, respectively. The projection of the reconstructed nipple was measured at the time of surgery and at 3, 6, and 9 months postoperatively. Results The nine-month average maintenance of nipple projection was $73.0%{\pm}9.67%$ for the LD flap group using an O-strut, $72.0%{\pm}11.53%$ for the TRAM flap group using an I-strut, and $69.0%{\pm}10.82%$ for the tissue expander/implant group using an L-strut. There were no cases of infection, wound dehiscence, or flap necrosis. Conclusions The application of an acellular dermal matrix with a different kind of strut for each of 3 breast reconstruction methods is an effective addition to current techniques for improving the maintenance of long-term projection in primary nipple reconstruction.

• Journal of Gastric Cancer
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• 제17권3호
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• pp.255-266
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• 2017

Purpose: Although Roux-en-Y (R-Y) reconstruction after distal gastrectomy has several advantages, such as prevention of bile reflux into the remnant stomach, it is rarely used because of the technical difficulty. This prospective randomized clinical trial aimed to show the efficacy of a novel method of R-Y reconstruction involving the use of 2 circular staplers by comparing this novel method to Billroth-I (B-I) reconstruction. Materials and Methods: A total of 118 patients were randomly allocated into the R-Y (59 patients) and B-I reconstruction (59 patients) groups. R-Y anastomosis was performed using two circular staplers and no hand sewing. The primary end-point of this clinical trial was the reflux of bile into the remnant stomach evaluated using endoscopic and histological findings at 6 months after surgery. Results: No significant differences in clinicopathological findings were observed between the 2 groups. Although anastomosis time was significantly longer for the patients of the R-Y group (P<0.001), no difference was detected between the 2 groups in terms of the total surgery duration (P=0.112). Endoscopic findings showed a significant reduction of bile reflux in the remnant stomach in the R-Y group (P<0.001), and the histological findings showed that reflux gastritis was more significant in the B-I group than in the R-Y group (P=0.026). Conclusions: The results of this randomized controlled clinical trial showed that compared with B-I reconstruction, R-Y reconstruction using circular staplers is a safe and feasible procedure. This clinical trial study was registered at www.ClinicalTrials.gov (registration No. NCT01142271).

• Maxillofacial Plastic and Reconstructive Surgery
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• 제36권5호
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• pp.214-218
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• 2014

Macroglossia can create dental and skeletal instability after orthodontic treatment or orthognathic surgery for mandibular prognathism. In relevant literature, partial glossectomy is suggested for a good post-treatment prognosis. Most of the published partial glossectomy cases are two-staged surgery, because of concern about postoperative airway obstruction. As orthognathic surgical techniques and fixation method develop, however, concerns about postoperative airway obstruction have lessened. In this case, mandibular setback surgery and partial glossectomy were performed simultaneously, leading to stable recovery without any postoperative respiratory problems. After surgical technique to preserve the tongue tip, we achieved good outcomes without postoperative side effects of lingual hypoesthesia, pronunciation disorder and dyskinesia. We report this case with a literature review.

• Clinics in Shoulder and Elbow
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• 제1권1호
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• pp.26-34
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• 1998

The management of acute acromioclavicular dislocations has usually followed the accepted principles of obtaining an anatomical reduction of the joint and maintaining it until soft tissue healing has occurred. So, the preferred treatment for acute acromioclavicular dislocation is controversial. We analysed operatively treated twenty-eight cases for acute acromioclavicular dislocation between February 1994 and January 1997 and reviewed postoperatively to evaluate the results of three different methods. We collected retrospectively the data via clinical history, associated injury, type of injury, radiographic review, Taft score, and final results. Follow up time averaged 14 months. (range, 12 to 21 ) In according to Rockwood's classification, ]7 cases were type Ⅲ, 1 case was type IV, and 10 cases were type V. Ten cases were treated with the modified Phemister method, ten cases with the modified Bosworth method and eight cases with the modified Weaver-Dunn method. ]n patients treated by modified Phemister method, the Taft score was 9.4 points and 8 cases achieved good or excellent results. In patients treated by modified Bosworth method, the Taft score was 9.8 points and 8 cases achieved good or excellent results. In patients treated by modified Weaver-Dunn method, the Taft score was 10.3 points and 7 cases achieved good or excellent results. The overall Taft score was 9.9 points and 23 cases achieved good or excellent results. There were four complications, such as calcification or metallic loosening or breakage of K-wire, but did not influence late results. In conclusions, there was no significant difference of results regarding the different three methods. However, our results indicated that the coracoclavicular ligament reconstruction by transfer of coracoacromial ligament produced better results.

• 대한족부족관절학회지
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• 제18권3호
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• pp.100-107
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• 2014

Purpose: The purpose of this study is to evaluate the efficacy of mesenchymal stem cell (MSC) isolation by the magnetic-activated cell sorting (MACS) method in tendon tissue-derived cells compared to the colony picking method for isolation of MSCs by picking colony-forming cells. Materials and Methods: Human tendon-derived cells were isolated by enzyme digestion using normal tendon tissues from three donors. We used the magnetic kit and well-known MSC markers (CD90 or CD105) to isolate MSCs in tendon-derived cells using MACS. Cloning cylinders were used to isolate colony-forming cells having MSC characteristics in tendon-derived cells. Colony-forming unit-fibroblast (CFU-F) assay was used to evaluate the self-renewal capacity of cells isolated using the colony picking method or MACS. For comparison of differentiation potentials into osteogenic or adipogenic lineage between two groups, alizarin red S and oil red O staining were performed at 14 days after induction of differentiation in vitro. Results: Flow cytometry results showed that early passage tendon-derived cells expressed CD44 in 99.13%, CD90 in 56.51%, and CD105 in 86.19%. In the CFU-F assay, CD90+ or CD105+ cells isolated with MACS showed larger colony formation in size than cells isolated using the colony picking method. We also observed that CD90+ or CD105+ cells were constantly differentiated into both osteogenic and adipogenic lineages in cells from all donors, whereas cells isolated using the colony picking method were heterogeneous in differentiation potentials to the osteogenic and adipogenic lineages. Conclusion: CD90+ or CD105+ cells isolated using MACS showed superior MSC characteristics in the self-renewal and multi-differentiation capacities compared with cells isolated using the colony picking method.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제23권5호
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• pp.422-427
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• 2001

Anterior segmental osteotomy were performed in 8 patients with Angle's II malocclusion or anterior maxillary protrusion. Cupar's method was used for operation. The period of follow up for patients were 15 months by average. This study discussed the postoperative complications and soft tissue change after anterior segmental maxillary osteotomy. There are not specific major complications.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제27권1호
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• pp.71-75
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• 2005

This study evaluated retrospectively the treatment method and postoperative complications of communited mandibular fractures. We analyzed the clinical and radiologic data of 14 patients with the comminuted mandibular fractures who were admitted to Chosun University Dental Hospital from January 1998 to December 2003. We reviewed the cause of trauma, fracture sites, treatment methods, and postoperative complications. Thirteen patients (93%) had a successful treatment outcome without complications. Only one patient developed postoperative osteomyelitis requiring early plate removal and sequestrectomy. For the comminuted fractures of mandible, internal fixation using micro- or mini-plate was an effective treatment method with a low incidence of major complications.