• 한국산업융합학회 논문집
• /
• 제15권2호
• /
• pp.43-47
• /
• 2012

In this study, the experiments for surface enhancement of silver mirror substrate were done, where we checked the characteristics of silver mirror substrate made by Tollen's method. The surface enhancement of Bromothymol blue was analyzed by three kind of silver mirror substrates. The assignments of the vibrational bands shown in SERS spectra are given based on both literature and the semi-empirical calculations at the PM3 methods. Finally, we deduced that the adsorption orientation of bromothymol blue was little tilted flat to the silver mirror surfaces by using of the surface selection rules.

• 한국전기전자재료학회논문지
• /
• 제32권6호
• /
• pp.458-461
• /
• 2019

The facile synthesis of shape-controlled Pd nanoparticles (PdNPs) with ascorbic acid as a reducing agent and cetyltrimethylammonium bromide (CTAB) as a capping agent is presented in this study. The synthesized PdNPs were characterized by UV-vis spectroscopy, transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray diffraction (XRD), and Raman Spectroscopy. The prepared PdNPs show efficient surface-enhanced Raman scattering (SERS) properties. SERS studies on the adsorption characteristics of 1,4-phenylene diisocyanide (1,4-PDI) on colloidal PdNPs have revealed that the relative peak intensity of the $(NC)_{free}$ and $(NC)_{bound}$ modes distinctly depends on the 1,4-PDI concentration as well as the shape of the PdNPs. Furthermore, we found that the PdNPs are also efficient photoelectron emitters such that the SERS spectrum of 4-nitrobenzenethiol (4-NBT) on PdNPs is readily converted to that of 4-aminobenzenethiol (4-ABT) under 632.8 nm radiation.

• Bulletin of the Korean Chemical Society
• /
• 제34권2호
• /
• pp.443-446
• /
• 2013

In this work, a novel strategy is provided to prepare silver nanoplates by a fibronectin (Fn) nanofibril template. First, Fn molecules were controlled to assemble into amyloid-like nanofibrils in highly concentrated ethanol aqueous solution. The resultant nanofibrils could serve as a soft template to direct the formation of silver nanoplates. It is worth noting that the silver nanoplates are excellent surface-enhanced Raman scattering (SERS) substrate with 4-aminothiophenol (4-ATP) molecule as a test probe. This high active SERS substrate can also be used to detect drug molecule, 2-thiouracil with high sensitivity.

• Bulletin of the Korean Chemical Society
• /
• 제34권11호
• /
• pp.3195-3196
• /
• 2013

• Advances in nano research
• /
• 제14권4호
• /
• pp.313-327
• /
• 2023

Zinc metal organic framework (MOF_Zn)-loaded goad nanoparticles (AuNPs) sol (Au@MOF_Zn), which was characterized by TEM, Mapping, FTIR, XRD, and molecular spectrum, was prepared conveniently by solvothermal method. The results indicated that Au@MOF_Zn had a very strong catalytic effect with the nanoreaction of AuNPs formation between sodium oxalate (SO) and HAuCl4. AuNPs in the new indicator reaction had a strong resonance Rayleigh scattering (RRS) signal at 370 nm. The indicator AuNPs generated by this reaction, which had the most intense surface enhanced Raman scattering (SERS) peak at 1621 cm -1. The new SERS/RRS indicator reaction in combination with specific aptamer (Apt) to fabricate a sensitive and selective Au@MOF_Zn catalytic amplification-aptamer SERS/RRS assay platform for carbendazim (CBZ), with SERS/RRS linear range of 0.025-0.5 ng/mL. The detection limit was 0.02 ng/mL. Similarly, this assay platform has been also utilized to detect oxytetracycline (OTC) and profenofos (PF).

• 한국진공학회:학술대회논문집
• /
• 한국진공학회 2013년도 제45회 하계 정기학술대회 초록집
• /
• pp.87-87
• /
• 2013

The interface between nanomaterials and biosystems is emerging as one of the broadest and most dynamic areas of science and technology, bringing together biology, chemistry, physics and many areas of engineering, biomedicine. The combination of these diverse areas of research promised to yield revolutionary advances in healthcare, medicine, and life science. For example, the creation of new and powerful nanosensors that enable direct, sensitive, and rapid analysis of biological and chemical species can advance the diagnosis and treatment of disease, discovery and screening of new drug molecules. Nanowire based sensors are emerging as a powerful and general platform for ultrasensitive and multiplex detection of biological and chemical species. Here, we present the studies about noble metal nanowire sensors that can be used for sensitive detection of a wide-range of biological and chemical species including nucleic acids, proteins, and toxic metal ions. Moreover, the optical and electrochemical applications of noble metal nanowires are introduced. Noble metal nanowires are successfully used as plasmonic antennas and nanoelectrodes, thereby provide a pathway for a single molecule sensor, in vivo neural recording, and molecular injection and detection in a single living cell.

• Korean Chemical Engineering Research
• /
• 제50권4호
• /
• pp.738-742
• /
• 2012

본 연구에서는 알루미나 나노 템플레이트(anodic alumina oxide; AAO)를 이용하여 신속하면서도 효과적으로 나노입자 및 바이오물질을 분리, 농축할 수 있는 나노필터 소자를 개발하였다. 본 연구에서 사용한 나노필터 소자는 유체의 주입 및 흐름이 가능한 미세유체채널(microfluidic channel)을 PDMS에 패터닝하였다. 위아래로 형성된 PDMS 미세유체채널 사이로, 다양한 크기의 나노 다공을 형성하고 있는 AAO 막을 삽입하여 크기에 따른 나노입자 및 바이오 물질을 분리할 수 있었다. 위아래로 PDMS 유체채널과 AAO 분리막을 집적하고, 최종적으로 아크릴레이트 플락스틱(acrylic plastic)으로 전체 소자를 고정하여 나노필터유체소자를 제작하였다. 완성된 나노필터소자를 이용하여 나노입자의 농축효율 및 은나노입자가 뭉쳐져있는 필터존(filtration zone)으로부터 뎅기 바이러스(dengue virus)를 표면증강라만(surface enhanced Raman scattering)분석법에 의해 검출할 수 있었다.

• ETRI Journal
• /
• 제26권1호
• /
• pp.38-44
• /
• 2004

Searching for systems of self-assembled monolayers (SAMs) that can be used as templates for chemical lithography, we found that nitro groups on aromatic SAMs are selectively converted on Ag to amino groups by irradiation with a visible laser. 4-nitrobenzenethiol on Ag was thus converted to 4-aminobenzenethiol by irradiating it with an $Ar^+$ laser. This was evident from surface-enhanced Raman scattering (SERS) as well as from a coupling reaction forming amide bonds. The surface-induced photoreaction allowed us to prepare patterned binary monolayers on Ag that showed different chemical reactivities. Using the binary monolayers as a lithographic template, we induced site-specific chemical reactions, such as the selective growth of biominerals on either the nitro- or amine-terminated regions by adjusting the crystal-growth conditions. We also demonstrated that patterned, amine-terminated monolayers can be fabricated even on gold by using silver nanoparticles as photoreducing catalysts.

• 대한화학회지
• /
• 제57권5호
• /
• pp.618-624
• /
• 2013

코어-쉘 형태의 금@은 나노입자가 재구성된 자기조립 블록공중합체 역마이셀 박막에 선택적으로 결합하여 특정 클러스터 배열을 형성하도록 유도하였고, 생성된 배열에 대하여 나노입자 사이의 상호작용에 따른 국소 표면 플라즈몬 결합 현상을 고찰하였다. 금@은 나노입자 배열을 제조하기 위해 폴리스티렌-블록-폴리(4-비닐피리딘) 역마이셀 박막을 주형으로 선택하였으며, 특정 용매 처리에 의해 선택적으로 유도되는 역마이셀 박막의 재구성 현상을 바탕으로, 폴리비닐피롤리돈으로 안정화된 금@은 나노입자의 도입 방법에 따라 규칙적이거나 무질서한 두가지 유형의 금@은 나노입자의 배열을 제조하였다. 금@은 나노입자를 안정화시키기 위하여 사용한 리간드 종류, 금 코어와 은 쉘의 결합, 은 쉘의 두께 변화, 및 금@은 나노입자의 배열 형태 등의 다양한 변수에 따라 발현되는 국소 표면 플라즈몬 결합 현상을 자외선-가시광 흡광 스펙트럼으로 관찰하였다. 최종적으로 나노입자 배열을 표면 증강 라만 산란 현상을 고찰하기 위한 기판으로써 응용하였으며 금@은 나노입자 패턴의 결합 정도에 상응하는 현저히 증강된 라만 신호를 관찰하였다.

• 한국진공학회:학술대회논문집
• /
• 한국진공학회 2014년도 제46회 동계 정기학술대회 초록집
• /
• pp.413-413
• /
• 2014

In this paper, we present a fabrication method of functionalized gold nanostructures on flexible substrate that can be implemented for plasmonic sensing application. For biomolecular sensing, many researchers exploit unconventional lithography method like nanoimprint lithography (NIP), contact transfer lithography, soft lithography, colloidal transfer printing due to its usability and easy to functionalization. In particular, nanoimprint and contact transfer lithography need to have anti-adhesion layer for distinctive metallic properties on the flexible substrates. However, when metallic thin film was deposited on the anti-adhesion layer coated substrates, we discover much aggravation of the mold by repetitive use. Thus it would be impossible to get a high quality of metal nanostructure on the transferred substrate for developing flexible electronics based transfer printing. Here we demonstrate a method for nano-pillar mold and transfer the controllable nanoparticle array on the flexible substrates without an anti-adhesion layer. Also functionalization of gold was investigated by the different length of thiol applied for effectively localized surface plasmonic resonance sensing. First, a focused ion beam (FIB) and ICP-RIE are used to fabricate the nanoscale pillar array. Then gold metal layer is deposited onto the patterned nanostructure. The metallic 130 nm and 250 nm nanodisk pattern are transferred onto flexible polymer substrate by bi-layer functionalized contact imprinting which can be tunable surface energy interfaces. Different thiol reagents such as Thioglycolic acid (98%), 3-Mercaptopropionic acid (99%), 11-Mercaptoundecanoic acid (95%) and 16-Mercaptohexadecanoic acid (90%) are used. Overcoming the repeatedly usage of the anti-adhesion layer mold which has less uniformity and not washable interface, contact printing method using bi-layer gold array are not only expedient access to fabrication but also have distinctive properties including anti-adhesion layer free, functionalized bottom of the gold nano disk, repeatedly replicate the pattern on the flexible substrate. As a result we demonstrate the feasibility of flexible plasmonic sensing interface and anticipate that the method can be extended to variable application including the portable bio sensor via mass production of stable nanostructure array and other nanophotonic application.