• 한국콘텐츠학회논문지
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• 제11권8호
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• pp.123-133
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• 2011

본 논문에서는 3차원 물체를 카툰 스타일로 렌더링하는 툰 쉐이딩에 3차원 텍스처를 활용하는 새로운 방법론을 제안한다. 1차원 텍스처를 사용하는 기존의 툰 쉐이딩에서는 주어진 조명 벡터와 물체 곡면의 법선 벡터 간의 상대적인 위치와 방향에 따라 쉐이딩 톤을 표현하고 있다. 1차원 텍스처만으로는 시점에 따른 톤의 변화를 표현하는데 한계가 있으므로 Barla 등은 2차원 텍스처로 확장하여 원근감, 안개효과 등 시점에 따라 변화하는 효과를 1차원 추가하였다. 본 논문에서는 3차원 텍스처로 확장하여 곡률, 세일리언시, 좌표 등 물체의 기하정보를 또 다른 1차원으로 추가함으로써 만화적 스타일 다양화를 위한 2가지 확장을 시도한다. 첫 번째는 기하정보에 따라 실루엣이나 하이라이트를 강조하는 형태 과장 효과를 추가하는 것이고 두 번째는 스크린 톤이나 아웃포커싱 등 만화에서 자주 등장하는 만화 고유의 효과를 추가하는 것이다. 이 접근방식의 유효성은 여러 가지 3D 물체를 기존에 표현하지 못하는 다양한 만화적 스타일로 렌더링한 예를 보임으로써 증명한다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제30권6호
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• pp.465-473
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• 2004

Purpose : The essential triad for nerve regeneration is nerve conduit, supporting cell and neurotrophic factor. In order to improve the peripheral nerve regeneration, we used polyglycolic acid(PGA) tube and brain-derived neurotrophic factor(BDNF) gene transfected Schwann cells in sciatic nerve defects of SD rat. Materials and methods : Nerve conduits were made with PGA sheet and outer surface was coated with poly(lactic-co-glycolic acid) for mechanical strength and control the resorption rate. The diameter of conduit was 1.8mm and the length was 17mm Schwann cells were harvested from dorsal root ganglion(DRG) of SD rat aged 1 day. Schwann cells were cultured on the PGA sheet to test the biocompatibility adhesion of Schwann cell. Human BDNF gene was obtained from cDNA library and amplified using PCR. BDNF gene was inserted into E1 deleted region of adenovirus shuttle vector, pAACCMVpARS. BDNF-adenovirus was multiplied in 293 cells and purified. The BDNF-Adenovirus was then infected to the cultured Schwann cells. Left sciatic nerve of SD rat (250g weighing) was exposed and 14mm defects were made. After bridging the defect with PGA conduit, culture medium(MEM), Schwann cells or BDNF-Adenovirus infected Schwann cells were injected into the lumen of conduit, respectively. 12 weeks after operation, gait analysis for sciatic function index, electrophysiology and histomorphometry was performed. Results : Cultured Schwann cells were well adhered to PGA sheet. Sciatic index of BDNF transfected group was $-53.66{\pm}13.43$ which was the best among three groups. The threshold of compound action potential was between 800 to $1000{\mu}A$ in experimental groups which is about 10 times higher than normal sciatic nerve. Conduction velocity and peak voltage of action potential of BDNF group was the highest among experimental groups. The myelin thickness and axonal density of BDNF group was significantly greater than the other groups. Conclusion : BDNF gene transfected Schwann cells could regenerate the sciatic nerve gap(14mm) of rat successfully.