• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.7
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• pp.56-62
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• 2018

The bus bar is an electrical connection widely used for the power supply of skyscrapers and power distribution and industrial equipment electrical panels in industrial plants. There are various materials to be considered in the design of the bus bar, such as material based on the use environment, the sectional area according to the power capacity, the length of the surface circumference, and the tightening method. Even with a bus bar manufactured to a size of sufficient power capacity in the design, if the actual tightening is incorrect, it may lead to fire due to deterioration. For these reasons, a variety of research on the temperature rise of the electrical contact point has continued. However, the temperature rise of the contacts is a consequence of the result, not a direct cause. In this paper, the influence of contact resistance on the fastening force and the overlapping section of the bus bar are investigated by measuring the change in resistance from building the specimen. A total of eight bus bar specimens were manufactured and measured. Resistance was measured by varying the clamping force and the interval between overlapping sections when the specimens were crossed. We propose a safe power connection model by analyzing the contribution of these factors to the actual contact resistance change.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.5
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• pp.1-6
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• 2020

UAV (Unmanned Aerial Vehicles) are used widely for military purposes because they are more economical than general manned aircraft and satellites, and have easy access to the object. Recently, owing to the development of IT technology, UAV equipped with various sensors have been released, and their use is increasing in a wide range of fields, such as surveying, agriculture, meteorological observation, communication, broadcasting, and sports. An increasing number of studies and attempts have made use of it. On the other hand, existing research was related mostly to photogrammetry, but there has been a lack of analytical research on LiDAR (Light Detection And Ranging). Therefore, this study examined the characteristics of a UAV LiDAR sensor for the application of a geospatial information field. In this study, the performance of commercialized LiDAR sensors, such as the acquisition speed and the number of echoes, was investigated, and data acquisition and analysis were conducted by selecting Surveyor Ultra and VX15 models with similar accuracy and data acquisition distances. As a result, a DSM of each study site was generated for each sensor, and the characteristics of data density, precision, and acquisition of ground data from vegetation areas were presented through comparison. In addition, the UAV LiDAR sensor showed an accuracy of 0.03m ~ 0.05m. Hence, it is necessary to select equipment considering the characteristics of data for effective use. In the future, the use of UAV LiDAR may be suggested if additional data can be obtained and analyzed for various areas, such as urban areas and forest areas.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.2
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• pp.71-76
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• 2017

The roll damping problem in the design of ships and offshore structures remains a challenge to many researchers due to the fluid viscosity and nonlinearity of the phenomenon itself. In this paper, the study on viscous roll damping of a circular cylinder was carried out using forced oscillations. The roll moment generated by forced oscillation using a torque sensor was measured for each forced oscillation period and compared with the empirical formula. Although the magnitude of the measured torque from the shear force was relatively small, the results were qualitatively similar to those obtained from the empirical formula, and showed good agreement with the quantitative results in some oscillation periods. In addition, the flow around the circular cylinder wall was observed closely through the PIV measurements. Owing to the fluid viscosity, a boundary layer was formed near the wall of the circular cylinder, and a minute wave was generated by periodical forced oscillations at the free surface through the PIV measurement. In this study, the suitability of the empirical formula for the roll moment caused by viscous roll damping was verified by model tests. The wave making phenomenon due to the fluid viscosity around the wall of a circular cylinder was testified by PIV measurements.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.23
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• pp.10209-10215
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• 2015

To assess the contribution of tumor necrosis factor $(TNF){\beta}$ +252 polymorphisms to risk and prognosis of hepatocellular carcinoma (HCC), we enrolled 150 pairs of sex- and age-matched patients with HCC, patients with cirrhosis alone, and unrelated healthy controls. $TNF{\beta}$ +252 genotypes were determined by polymerase chain reaction with restriction fragment length polymorphism. Multivariate analysis indicated that $TNF{\beta}$ G/G genotype [odds ratio (OR), 3.64; 95%CI, 1.49-8.91], hepatitis B surface antigen (OR, 16.38; 95%CI, 8.30-32.33), and antibodies to hepatitis C virus (HCV) (OR, 39.11; 95%CI, 14.83-103.14) were independent risk factors for HCC. There was an additive interaction between $TNF{\beta}$ G/G genotype and chronic hepatitis B virus (HBV)/HCV infection (synergy index=1.15). Multivariate analysis indicated that factors associated with $TNF{\beta}$ G/G genotype included cirrhosis with Child-Pugh C (OR, 4.06; 95%CI, 1.34-12.29), thrombocytopenia (OR, 6.55; 95%CI, 1.46-29.43), and higher serum ${\alpha}$-fetoprotein concentration (OR, 2.53; 95%CI, 1.14-5.62). Patients with $TNF{\beta}$ G/G genotype had poor cumulative survival (p=0.005). Cox proportional hazard model indicated that $TNF{\beta}$ G/G genotype was a biomarker for poor HCC survival (hazard ratio, 1.70; 95%CI, 1.07-2.69). In conclusion, there are independent and additive effects between $TNF{\beta}$ G/G genotype and chronic HBV/HCV infection on risk for HCC. It is a biomarker for poor HCC survival. Carriage of this genotype correlates with disease severity and advanced hepatic fibrosis, which may contribute to a higher risk and poor survival of HCC. Chronic HBV/HCV infected subjects with this genotype should receive more intensive surveillance for early detection of HCC.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2005.11a
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• pp.339-347
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• 2005

A type IP-2 transport package should prevent a loss or dispersal of the radioactive contents and a more than $20\%$ increase in the maximum radiation level at any external surface of the package when it were subjected to the drop test under the normal conditions of transport. If a shielding thickness of IP-2 transport package is thick, a bolted lid type may prevent a loss or dispersal of the radioactive contents than the door type of ISO containers which are generally used as a type IP-2 transport package. In this paper, to evaluate the effect of drop directions on the bolt tension and the coherence of a bolt, the drop tests of preliminary small model are tested and evaluated for seven directions before the drop test of a type IP-2 transport package with a bolted lid type under the normal conditions of transport. Seven drop directions which are a bottom-vertical drop, a lid-vortical drop. a horizontal drop and four corner drops have been carried out. Using a force sensor, the bolt tension during the drop impact is measured. The coherence of bolt is evaluated by the difference between the fastening torque of bolt before a drop test and the unfastening torque of bolt after a drop impact.

• Journal of the Korea Organic Resources Recycling Association
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• v.23 no.2
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• pp.53-60
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• 2015

Newly, nutrients recovery by bioconversion in the swine waste which caused serious problems due to its high organic fraction and content of nutrients such as phosphorus and nitrogen is viewed as a considerable approach since it produces valuable product as well as recycling of resources. Consequently, it is necessary to find new methods to treat swine waste. One possible solution to this problem is to use this potential pollutant as a growth substrate for economically valuable products. The study for the fundamental improvement of bioconversion efficiency by finding optimum growth conditions using statistical models and biotechnology was performed. A novel approach to utilize swine waste by cultivating mycelia of the mushroom Phellinus linteus are described. A central composite face-centered design (CCF) for the experiments was used to develop empirical model providing a quantitative interpretation of the relationships among the three variables, which were substrate concentration, pH, and temperature. The maximal radial extension rate (2.78mm/d) of P.linteus was determined under the condition of 5.0 g COD/L, pH 5.0, and temperature $29.7^{\circ}C$. The results of this study suggest that swine waste could be utilized as a growth substrate for the cultivation of mushroom mycelia enhancing an efficiency of utilizing this by-product of the livestock industry.

• Journal of Biomedical Engineering Research
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• v.38 no.3
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• pp.116-122
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• 2017

Physical breast phantoms would be useful for the development of a dedicated breast computed tomography (BCT) system and its optimization. While the conventional breast phantoms are available in compressed forms, which are appropriate for the mammography and digital tomosynthesis, however, the BCT requires phantoms in uncompressed forms. Although simple cylindrical plastic phantoms can be used for the development of the BCT system, they will not replace the roles of uncompressed phantoms describing breast anatomies for a better study of the BCT. In this study, we have designed a numerical voxel breast phantom accounting for the random nature of breast anatomies and applied it to the 3D printer to fabricate the uncompressed anthropomorphic breast phantom. The numerical voxel phantom mainly consists of the external skin and internal anatomies, including the ductal networks, the glandular tissues, the Cooper's ligaments, and the adipose tissues. The voxel phantom is then converted into a surface data in the STL file format by using the marching cube algorithm. Using the STL file, we obtain the skin and the glandular tissue from the 3D printer, and then assemble them. The uncompressed breast phantom is completed by filling the remaining space with oil, which mimics the adipose tissues. Since the breast phantom developed in this study is completely software-generated, we can create readily anthropomorphic phantoms accounting for diverse human breast anatomies.

• Journal of Korean Neurosurgical Society
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• v.29 no.6
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• pp.731-737
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• 2000

Objective : Growth factor receptors on the tumor cells are known to be expressed highly allowing the tumor cells to bind growth factors to stimulate cellular division. Immunotoxin therapy is one of the novel approaches to the primary malignant brain tumor, and expression of cell-surface receptor is essential for the immunotoxin to have specific anti-tumor activity. Despite promising cytotoxic activity of immunotoxin, tumor responses are not curative on clinical trials, and additional studies are needed regarding various factors influencing the efficacy of the immunotoxin. The purpose of this study is to detect the expression of various growth factor receptors on brain tumor cell lines which are going to be used in these studies. Materials and Methods : The authors detected transferrin receptor(TR), insulin-like growth factor-1 receptor(IGF-1R), and interleukin-4 receptor(IL-4R) on medulloblastoma cell line(Daoy) and glioblastoma cell lines(U373 MG and T98 G) by flow cytometric analysis. Results : TR was expressed on Daoy, U373 MG, and T98 G. IGF-1R was expressed on Daoy and U373 MG, but not on T98 G. IL-4R was expressed on all cell lines tested. Conclusion : The transferrin and interleukin-4 receptors might be good targets for immunotoxin therapy. The results should be considered in additional in vitro and in vivo studies regarding immunotoxin and in establishing the proper treatment model of the immunotoxin therapy including selection of the adequate immunotoxin.

• Journal of the Korean Applied Science and Technology
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• v.36 no.4
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• pp.1243-1252
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• 2019

The purpose of this study is to investigate the optimum conditions of biomass pretreatment with potassium hydroxide (KOH) for efficient utilization of cellulose, hemicellulose and lignin from Miscanthus. The optimization of variables was performed by response surface methodology (RSM). The variation ranges of the parameters for the RSM were potassium hydroxide 0.2~0.8 M, reaction temperature 110~190℃ and reaction time 10~90 min. The optimum conditions of alkali pretreatment from Miscanthus were determined as follows: concentration of KOH 0.47 M, reaction temperature 134℃ and reaction time 65 min. At the optimum conditions, the yield of cellulose from the solid fraction after pretreatment was predicted to be 95% by model prediction. Finally, 66.1 ± 1.1% of cellulose were obtained by verification experiment under the optimum conditions. The order contents of solid extraction were hemicellulose 26.4 ± 0.4%, lignin 3.7 ± 0.1% and ash 0.5 ± 0.04%. The yield of ethanol concentration of 96% was obtained using separated saccharification and fermentation.

• YAKHAK HOEJI
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• v.41 no.3
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• pp.305-311
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• 1997

Sustained release-microspheres and immediate release-pellets were prepared to develop a controlled release multiparticulate system containing both water soluble and insoluble dr ug. Pseudoephedrin.HCl (EPD) and terfenadine (TRF) were used as model drugs, respectively. Sustained release-EPD microspheres were prepared by solvent evaporation method using Eudragit RL or RS as a matrix combined with pH-insensitive film coating. Smaller EPD microspheres were obtained when smaller amount of Eudragit as a matrix material or larger amount of magnesium stearate as a dispersing agent was used. However the obtained microspheres did not show syfficient sustained release characteristics. About 97% of EPD was released after 1 hr irrespective of matrix material used. Subsequent coating of the microspheres with pH-insensitive polymer such as Eudragit RS or ethylcelulose (EC) resulted good sustained in 37.5, 73.3 and 92.0% release of encapsulated EPD in distilled water after 1, 3 abd 7 hr, respectively. It corresponds to mean dissolution time (MDT) of 2.3 hr, which is much larger than that of un-coated EPD microspheres (0.0048 hr). Immediate release TRF pellets were prepared by spherically agglomerated crystallization using Eudragit E as an inert matrix and methylene chloride as a liquid binder. Using Eudragit E alone as a matrix resulted in satisfactory physical properties of the pellets such as sphericity, surface texture and flowability, but led to slower release of TRF from pellets than un-modified TRF powder (MDT of 1.70 vs 1.43 hr in pH 1.2 dissolution medium). Introducing propylene glycol or sodium lauryl sulfate as an emulsifier brought about faster release of TRF from pellets (MDT of 1.14 and 0.95 hr, respectively). In conclusion, microencapsulation by solvent evaporation combined with film coating and spherically agglomerated crystallization were successfully utilized to prepare controlled release multiparticulate system composed of sustained release EPD-microspheres and immediate release TRF pellets.