• Human Ecology Research
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• 제60권4호
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• pp.565-576
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• 2022

The purpose of this study is to identify the effect of Home Economics Instruction applying Flipped and Problem-Based Learning (FPBL) on Korean middle-school students' metacognition skill. The study uses a pre-post design test of the same group. There were 151 participants (77 male and 74 female) who were middle-school students in the third grade. Two hours of classes on 'Food Selection and Storage' were given per week for three weeks - a total of six hours. Analysis using the t-test revealed a statistically significant difference between the pre-test and the post-test, supporting the conclusion that participating in the class improved the metacognition, food selection, and storage behavior scores of the middle-school students. All area scores and overall averages of metacognitive sub-elements such as planning, monitoring, regulation, and evaluation also improved after taking FPBL classes. From the results of this study, Home Economics Instruction applying FPBL is an effective teaching method for improving middle-school students' metacognition.

• IMMUNE NETWORK
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• 제4권3호
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• pp.166-175
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• 2004

Background: Telomerase, a ribonucleoprotein enzyme capable of synthesizing telomeric repeats, attracts attention for its possible role in determining the replicative capacity of normal somatic cells, transformed cells, and cells of the germline lineage. Differently from normal somatic cells with no telomerase activity, normal lymphocytes has been reported to have telomerase activity comparable to that found in transformed cells during development and activation, which substantiate a role in supporting the capacity of lymphocytes for extensive clonal expansion. Methods: Here, in order to define the telomerase regulation in murine T lymphocytes, telomerase activity in cloned murine $CD8^+$ T cells and naive $CD8^+$ T cells isolated from C57BL/6 mice was examined. Next, the regulatory mechanism of telomerase activity at transcriptional and post- translational levels was investigated by determining the expression level of the TERT protein, a key component for telomerase activity. Results: It was demonstrated that telomerase activity was expressed in an inactivated state as well as in an activated state in the murine $CD8^+$ T lymphocytes by using TRAP assay. The increase of telomerase activity was partially dependent on the net increase of TERT expression. Also, telomerase activity was decreased after treatment with protein kinase inhibitors, indicating that telomerase activation was prevented by inhibition of phosphorylation. Conclusion: Therefore, these results suggest that telomerase activity is constitutively expressed in the murine resting T lymphocytes and controlled by both transcriptional regulation and post- ranslational modifications.

• Journal of Chest Surgery
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• 제22권4호
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• pp.601-608
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• 1989

We sought the relationship between the pulmonary artery development and cardiac performance from the analysis of the 36 cyanotic congenital heart disease patients [mainly TOF] who were operated and indwelled the pulmonary artery and left atrial pressure monitoring catheters for the postoperative care at the department of Thoracic and Cardiovascular Surgery SNUH in 1988. They were pre-evaluated of the pulmonary artery index from the cineangiographic films and post-operatively, calculated the cardiac index from the arterial and mixed venous blood gas and also measured the mean left atrial pressure and total inotropic supporting amount after operation. The post-operative cardiac indices were 3.46 * 1.03 1/min/M2 [immediate postoperative], 3.31 [ 1.08 [postoperative 6 hrs], 3.29 [ 1.01 [12 hrs], 3.54 * 1.02 [24 hrs], 3.92 * 1.14 [48 hrs], respectively. We divided the patients the group A and group B from the size of the pulmonary artery index, that is, group A was below 200 mm2/M2 and group B above 200 mm2/M2 of the pulmonary artery index. The cardiac indices and left atrial pressure between the group A and B were not different in the view of the statistical significance but the total post-operative inotropic amount of group A was more than group B and it was significant statistically. We concluded that the smaller the pulmonary artery index is, the more postoperative supportive treatment [for example, inotropics] for the enhancement of cardiac performance is needed, and indirectly, which means that the pulmonary artery index was correlated with the postoperative cardiac performance in cyanotic congenital heart disease.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제10권5호
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• pp.2427-2445
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• 2016

In contrast to traditional "store-and-forward" routing mechanisms, network coding offers an elegant solution for achieving maximum network throughput. The core idea is that intermediate network nodes linearly combine received data packets so that the destination nodes can decode original files from some authenticated packets. Although network coding has many advantages, especially in wireless sensor network and peer-to-peer network, the encoding mechanism of intermediate nodes also results in some additional security issues. For a powerful adversary who can control arbitrary number of malicious network nodes and can eavesdrop on the entire network, cryptographic signature schemes provide undeniable authentication mechanisms for network nodes. However, with the development of quantum technologies, some existing network coding signature schemes based on some traditional number-theoretic primitives vulnerable to quantum cryptanalysis. In this paper we first present an efficient network coding signature scheme in the standard model using lattice theory, which can be viewed as the most promising tool for designing post-quantum cryptographic protocols. In the security proof, we propose a new method for generating a random lattice and the corresponding trapdoor, which may be used in other cryptographic protocols. Our scheme has many advantages, such as supporting multi-source networks, low computational complexity and low communication overhead.

• Molecules and Cells
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• 제26권1호
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• pp.5-11
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• 2008

Stalled DNA replication forks activate specific DNA repair mechanism called post-replication repair (PRR) pathways that simply bypass DNA damage. The bypassing of DNA damage by PRR prevents prolonged stalling of DNA replication that could result in double strand breaks (DSBs). Proliferating cell nuclear antigen (PCNA) functions to initiate and choose different bypassing pathways of PRR. In yeast, DNA replication forks stalled by DNA damage induces monoubiquitination of PCNA at K164, which is catalyzed by Rad6/Rad18 complex. PCNA monoubiquitination triggers the replacement of replicative polymerase with special translesion synthesis (TLS) polymerases that are able to replicate past DNA lesions. The PCNA interaction motif and/or the ubiquitin binding motif in most TLS polymerases seem to be important for the regulation of TLS. The TLS pathway is usually error-prone because TLS polymerases have low fidelity and no proofreading activity. PCNA can also be further polyubiquitinated by Ubc13/ Mms2/Rad5 complex, which adds an ubiquitin chain onto monoubiquitinated K164 of PCNA. PCNA polyubiquitination directs a different PRR pathway known as error-free damage avoidance, which uses the newly synthesized sister chromatid as a template to bypass DNA damage presumably through template switching mechanism. Mammalian homologues of all of the yeast PRR proteins have been identified, thus PRR is well conserved throughout evolution. Mutations of some PRR genes are associated with a higher risk for cancers in mice and human patients, strongly supporting the importance of PRR as a tumor suppressor pathway.

• 한국사회복지학
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• 제65권1호
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• pp.201-226
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• 2013

외환위기 이후 청년실업의 증가가 사회적 문제로 부각되었으나, 청년층의 노동시장 경험에 관한 연구는 제한적으로 이루어져 왔다. 본 연구에서는 노동경력을 단순한 일자리 이동과 달리 노동지위의 연속적 배열과 순서적이고 위계적인 변화과정으로 개념화하였으며, 배열분석을 활용하여 외환위기 전후 청년층의 노동경력을 노동지위의 다양한 측면에서 비교하였다. 분석 결과, 외환위기 이후 첫 일자리로의 이행기간이 장기화되고 고용형태와 사업장 규모 면에서 첫 일자리의 질적 저하가 발생하였음이 확인되었다. 또한 외환위기 이후 청년 코호트는 미취업형과 실업형, 비대기업형, 비정규직형 및 이동형 특성을 갖는 경력유형에 속할 상대적 위험률이 높았다. 이러한 결과는 전반적으로 외환위기 이후 청년층의 고용불안정성이 더 커졌으며, 내부노동시장형에 비해 외부노동시장형 경력유형이 상대적으로 증가한 것을 의미한다.

• 아동학회지
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• 제20권1호
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• pp.29-44
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• 1999

A major concern in the area of moral education is to find an effective educational method capable of supporting maturity of moral reasoning in young children. The purpose of the present study was to evaluate the effects of distributive dilemma discussion on children's distributive justice reasoning. The subjects were fifty 5-year-olds selected from a kindergarten in the city of Kumi. 26 children participated in a 10 week discussion intervention; another 24 children constituted the control group. The experimental procedure consisted of 3 parts; a pre-test to determine the experimental and control groups, moral discussions on dilemma situations based on 10 stories for the experimental group, and a post-test for both groups. The moral discussions were audio-taped. The results showed that children in the experimental group used more varied and elaborate distributive justice reasoning as the discussions proceeded. Moral discussions facilitated distributive justice reasoning.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2001년도 가을 학술발표회 논문집
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• pp.1097-1102
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• 2001

Seismic safety of continuous span concrete bridge can be enhanced by distributing a large seismic lateral load to each supporting pier. A new viscoelastic device called Shock Transmission Unit(STU), which is a simple cylinder-piston assembly packed with a so-called silicone putty compound, enables the lateral seismic load to be transmitted to the pier by installation of the device to movable bearings of the bridge. The seismic safety of concrete bridges having the STU depends on not only safety of the bridges globally but also safety of anchor systems which anchors the STU to concrete pier. An experimental investigation is performed to study the behavior of cast-in-place anchor and post-installed anchor subjected to shear load statically and cyclically according to different edge distance, embedment length, and anchor spacing. Finally, the experimental results are compared with results by design methods of ACI and CCD, and results by FEM analysis.

• 한국농공학회지
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• 제44권3호
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• pp.101-110
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• 2002

Most of the agricultural structures are in shortage of feasible facility management because these structures are small in size and spacially distributed in rural area. Inspection tools based on visual inspections are generally used for agricultural structures in most of the countries, including Korea. It is necessary to survey data of the irrigation structures to maintain records, and to develop the interface program by constructing database of inspection data. This study was conducted to develop a system for safe appraisal and repair works on agricultural irrigation structures. Repair and rehabilitation method can be chosen from an optimum viewpoint if the information between the method and life-cycle management cost of agricultural structures is constructed in the database. In this study, the system assisting onsite field investigation and determining the typical rehabilitation method of typical agricultural structural problems such as fractures and cracks of members was developed.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2005년도 추계 학술발표회 제17권2호
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• pp.579-582
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• 2005

Tunnel lining is the final support of a tunnel and reflects the results of the interaction between ground and support system. Recently it is very difficult to support and manage the tunnel because the cracks on tunnel lining cause problems in supporting and managing tunnels. Therefore the analysis of the cracks is quite strongly required. The major role played by the steel fiber occurs in the post-cracking zone, in which the fibers bridge across the cracked matrix. Because of its improved ability to bridging cracks, steel fiber reinforcement concrete(SFRC) has better crack properties than that of reinforced concrete. In this study, mechanical behaviour of a tunnel lining was examined by model tests. The model tests were carried out under various conditions taking different loading shapes, thicknesses and leakage of lining, and volume content of steel fiber. From these model test, the cracking load, the failure load, defection and cracking position and type were examined and the characteristics of deformation and failure for tunnel lining were estimated and researched.