• Archives of Hand and Microsurgery
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• v.23 no.4
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• pp.290-295
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• 2018

Author planed peroneal artery perforator flap for ankle reconstruction and experienced successful result using sural neuro-lesser saphenous venous flap due to an unexpected event. A male Asian patient, 24 years old, had a history of recurrent operation wound disruption in the ankle region. Under general anesthesia, peroneal perforator and saphenous vein, as well as the sural nerve branches, were identified and preserved. In the process of flap rotation, an accidental division of peroneal artery perforator has occurred. Despite the division of the perforator, circulation was normal. The patient experienced no complication after the surgery. Some study reported that accompanying arteries and the vascular plexus around the sural nerve communicate. In conclusion, sufficient blood supply was possible only with the accompanying artery of the sural nerve without peroneal perforator. So, it is essential to always preserve not only perforator but also neurovascular bundles at any circumstances and any location.

• Korean Journal of Construction Engineering and Management
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• v.20 no.3
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• pp.105-112
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• 2019

Due to abnormal high temperature, electric power demand has exceeded the backup power reserved for emergency case, hence, resulting in a major power outage. In today's overcrowded cities, the unexpected disruption in energy supply and demand is a major threat to the enormous economic damage and urban malfunctions. Existing methods for estimating the demand of the emergency power source do not lend themselves to predict the actual demand in the spatial dimension of the city. In addition, the reserve power is arbitrarily distributed in the case of emergency. This paper presents a method that predicts the emergency power demand using the spatial distribution of emergency power demand by applying the daily energy consumption intensity and emergency power demand according to urban spatial information and building use.

• Journal of The Geomorphological Association of Korea
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• v.25 no.1
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• pp.31-45
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• 2018

This study investigated the characteristics of sedimentary environment changes across a tidal flat in Gagyeongju of Anmyeondo Island. We performed a spatio-temporal analysis on the grain sizes composition of sediments and micro-landform changes during the winter from 2013 to 2016. The results showed that erosion was a dominant processthroughout the study flat, reducing the surface elevation even by 1 m around the upper sand flat. As a consequence, headlands have formed in the entire region of Gagyeongju village. In addition, erosion quickly progressed along the low-lying subtidal zone and tide way and, in contrast, sedimentation progressed in the mid-elevation tidal flat. We posit that a jetty, which had been constructed as a pier facility on the eastern part of the study area, interfered with the flow of tidal current, thereby enhancing these erosional processes. This is because such interference can block the supply of fine-textured sediments from the nearby Cheonsu Bay and therefore reduce surface elevation. According to the surface sediment analysis, the sediments were categorized into 7 sedimentary facies, and generally displayed a high ratio of silt and clay. The result of time-series analysis (2012-2013) showed that the sediments on the tidal flat became fine-grained, and that sorting became worse. However, the sediments on the subtidal zone, embayment and along inside of the jetty tended to be coarse-grained. In conclusion, the tidal flat microlandform change in the study area was caused by a disruption in the seawater circulation due to the jittery construction within the tidal flat, which had a direct effect on erosional and sedimentary environment processes.

• Journal of Veterinary Science
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• v.23 no.6
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• pp.84.1-84.15
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• 2022

Background: Stroke is caused by disruption of blood supply and results in permanent disabilities as well as death. Chlorogenic acid is a phenolic compound found in various fruits and coffee and exerts antioxidant, anti-inflammatory, and anti-apoptotic effects. Objectives: The purpose of this study was to investigate whether chlorogenic acid regulates the PI3K-Akt-Bad signaling pathway in middle cerebral artery occlusion (MCAO)-induced damage. Methods: Chlorogenic acid (30 mg/kg) or vehicle was administered peritoneally to adult male rats 2 h after MCAO surgery, and animals were sacrificed 24 h after MCAO surgery. Neurobehavioral tests were performed, and brain tissues were isolated. The cerebral cortex was collected for Western blot and immunoprecipitation analyses. Results: MCAO damage caused severe neurobehavioral disorders and chlorogenic acid improved the neurological disorders. Chlorogenic acid alleviated the MCAO-induced histopathological changes and decreased the number of terminal deoxynucleotidyl transferase dUTP nick end labeling-positive cells. Furthermore, MCAO-induced damage reduced the expression of phospho-PDK1, phospho-Akt, and phospho-Bad, which was alleviated with administration of chlorogenic acid. The interaction between phospho-Bad and 14-3-3 levels was reduced in MCAO animals, which was attenuated by chlorogenic acid treatment. In addition, chlorogenic acid alleviated the increase of cytochrome c and caspase-3 expression caused by MCAO damage. Conclusions: The results of the present study showed that chlorogenic acid activates phospho-Akt and phospho-Bad and promotes the interaction between phospho-Bad and 14-3-3 during MCAO damage. In conclusion, chlorogenic acid exerts neuroprotective effects by activating the Akt-Bad signaling pathway and maintaining the interaction between phospho-Bad and 14-3-3 in ischemic stroke model.

• Smart Media Journal
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• v.12 no.5
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• pp.81-87
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• 2023

In this paper, accidents in high-voltage overhead distribution lines, which provide stable power supply in the power system, cause inconvenience in life and disruption of production of companies. 22.9 [kV] high-voltage overhead power distribution lines aim to improve reliability and stability, such as damage caused by rain, snow, wind, etc., or electric shock prevention. Therefore, in order to prevent wire disconnection accidents due to deterioration of electrical conductivity or tensile strength due to corrosion of overhead distribution lines, it is necessary to prevent unexpected accidents in the future through regular inspection and repair. In order to diagnose deterioration due to corrosion of distribution lines, a diagnostic system (measuring instrument) is installed on the wires to monitor the condition of the wires. The manager on the ground receives the measured data through ZigBee wireless communication, controls the diagnosis system through the diagnosis system program, and grasps the condition of the overhead distribution line through the measured data and photographed photos, and predicts the life of the wire along with the visual inspection method. developed a program.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.516-516
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• 2022

Agricultural reservoirs are critical water resources structures to ensure continuous water supplies for rice cultivation in Korea. Climate change has increased the risk of reservoir failure by exacerbating discrepancies in upstream runoff generation, downstream irrigation water demands, and evaporation losses. In this study, the variations in water balance components of 400 major reservoirs during 1973-2017 were examined to identify the reservoirs with reliable storage capacities and resilience. A conceptual lumped hydrological model was used to transform the incident rainfall into the inflows entering the reservoirs and the paddy water balance model was used to estimate the irrigation water demand. Historical climate data analysis showed a sharp warming gradient during the last 45 years that was particularly evident in the central and southern regions of the country, which were also the main agricultural areas with high reservoir density. We noted a country-wide progressive increase in average annual cumulative rainfall, but the forcing mechanism of the rainfall increment and its spatial-temporal trends were not fully understood. Climate warming resulted in a significant increase in irrigation water demand, while heavy rains increased runoff generation in the reservoir watersheds. Most reservoirs had reliable storage capacities to meet the demands of a 10-year return frequency drought but the resilience of reservoirs gradually declined over time. This suggests that the recovery time of reservoirs from the failure state had increased which also signifies that the duration of the dry season has been prolonged while the wet season has become shorter and/or more intense. The watershed-irrigated area ratio (W-I_ratio) was critical and the results showed that a slight disruption in reservoir water balance under the influence of future climate change would seriously compromise the performance of reservoirs with W-I_ratio< 5.

• Environmental and Resource Economics Review
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• v.20 no.4
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• pp.859-882
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• 2011

Since two oil crises in the 1970s, Korea has actively engaged in overseas E&P projects to increase energy diversity as well as its self-development rate of energy resources. Korea's energy self-development rate, an index that indicates the ratio of resources acquired through overseas development compared to direct imports. Currently, Korea is conducting a total of 180 promising overseas oil development projects in 36 countries as of the end of 2010. By now, it has secured a reserve of around 1.63 billion barrels and production of around 176 thousand barrels of oil per day. The self-development rate for oil rose from 2.8% in 2006 to 7.4% in 2010. Not content with these remarkable successes, the korean government is planning to raise its self-development rate in oil to 25% by 2019, by promoting the active participation of Korean companies in overseas oil development projects. This paper is concerned with estimation of the required amount of government subsidies that includes loans and financial support through state-controlled banking institutions in order to reach the target 25% rate by 2019. The estimation results shows that government subsidies of at least 268 million dollars are needed for the current rate of 7.4% in oil. However, the amount sharply increases up to 1.25 billion dollars in 2019 when domestic oil demand rises to 1.02 billion barrels.

• Health Policy and Management
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• v.34 no.2
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• pp.106-119
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• 2024

Drug shortage is a persistent phenomenon that poses a public health risk worldwide and occurs due to a range of causes. The purpose of this study is to review key policies to prepare for and respond to drug shortages in selected countries, such as the United States, Canada, and some European countries in order to draw implications. This study reviewed the reports and articles derived from search engines and Google Scholar by using keywords such as drug shortage and stock-out. Over the last decade or so, the United States have strengthened requirements on advance notification for disruption and interruption of drug manufacturing, established the Inter-agency Drug Shortages Task Force to promote the communication and coordination of responses, and expedited drug regulatory processes. Similarly, Canada established the Multi-Stakeholder Steering Committee on drug shortages by involving representatives from central and local governments and private sectors. Canada also adopted a tiered approach to the communication of drug shortages based on the assessment of the severity of the shortage problem and released a detailed information guide on communication. In 2019, the joint task force between the European Medicines Agency and the Heads of Medicines Agencies issued guidelines on drug shortage communication in the European Economic Area. The countries reviewed in this paper focus on communication across different stakeholders for the monitoring of and timely response to drug shortages. The efforts to protect public health from the negative impact of the drug shortage crisis would require multi-sectorial and multi-governmental coordination and development of guidelines.

• Journal of Wetlands Research
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• v.16 no.4
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• pp.303-318
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• 2014

Baseflow gives a significant contribution to stream function in the regions where climatic characteristics are seasonally distinct. In this regard, variable baseflow can make it difficult to maintain a stable water supply, as well as causing disruption to the stream ecosystem. Changes in land use can affect both the direct flow and baseflow of a stream, and consequently, most other components of the hydrologic cycle. Baseflow estimation depends on the observed streamflow in gauge watersheds, but accurate predictions of streamflow through modeling can be useful in determining baseflow data for ungauged watersheds. Accordingly, the objectives of this study are to 1) improve predictions of SWAT by applying the alpha factor estimated using RECESS for calibration; 2) estimate baseflow in an ungauged watershed using the WHAT system; and 3) evaluate the effects of changes in land use on baseflow characteristics. These objectives were implemented in the Gapcheon watershed, as an ungauged watershed in South Korea. The results show that the alpha factor estimated using RECESS in SWAT calibration improves the prediction for streamflow, and, in particular, recessions in the baseflow. Also, the changes in land use in the Gapcheon watershed leads to no significant difference in annual baseflow between comparable periods, regardless of precipitation, but does lead to differences in the seasonal characteristics observed for the temporal distribution of baseflow. Therefore, the Guem River, into which the stream from the Gapcheon watershed flows, requires strategic seasonal variability predictions of baseflow due to changes in land use within the region.