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Numerical calculation of the wind action on buildings using Eurocode 1 atmospheric boundary layer velocity profiles

  • Lopes, M.F.P.;Paixao Conde, J.M.;Gomes, M. Gloria;Ferreira, J.G.
    • Wind and Structures
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    • v.13 no.6
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    • pp.487-498
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    • 2010
  • When designing structures to the wind action, the variation of the mean wind velocity and turbulence parameters with the height above the ground must be taken into account. This paper presents the numerical simulation results of atmospheric boundary layer (ABL) airflows, in a numerical domain with no obstacles and with a cubic building. The results of the flow characterization, obtained with the FLUENT CFD code were performed using the ${\kappa}-{\varepsilon}$ turbulence model with the MMK modification. The mean velocity and turbulence intensity profiles in the inflow boundary were defined in accordance with the Eurocode 1.4, for different conditions of aerodynamic roughness. The maintenance of the velocity and turbulence characteristics along the domain were evaluated in an empty domain for uniform incident flow and the ABL Eurocode velocity profiles. The pressure coefficients on a cubic building were calculated using these inflow conditions.

Calcified Giant Thrombosis in the Right Atrium and Coronary Sinus with Persistent Left Superior Vena Cava - Report of 1 case - (우심방과 관정맥동내의 석회화된 거대혈전증을 동반한 좌상공정맥증 - 1례 보고-)

  • 정종수
    • Journal of Chest Surgery
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    • v.22 no.3
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    • pp.456-462
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    • 1989
  • We experienced one case of the calcified giant thrombosis in the enlarged right atrium and coronary sinus with markedly dilated persistent left superior vena cava and absent right superior vena cava in 29year old female patient. We supposed that the dilatation of persistent left superior vena cava was due to poststenotic dilatation secondary to obstruction on orifice of coronary sinus by thrombosis. The giant thrombosis in the right atrium and coronary sinus was successfully resected. She had improvement on preoperative chest discomfort but, the moderate hepatomegaly was developed and then she was discharged with incompletely recovered state due to economical poverty on postoperative 6th weeks. The continuous follow-up and study are indeed necessary for further evaluation of pathology and etiology.

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Studies on the Segmental Running of Splenic Tabecular Veins of Korean Cattle by the Vinylite Corrosion Technique (Vinyl 부식법(腐蝕法)에 의(依)한 한우비주정맥(韓牛脾柱靜脈)의 구역적(區域的) 주행(走行)에 관(關)한 연구(硏究))

  • Kim, Chong Sup
    • Korean Journal of Veterinary Research
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    • v.11 no.1
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    • pp.83-90
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    • 1971
  • The studies were conducted to ramify the splenic trabecular veins by injection of vinylite into the splenic veins in twenty five adult Korean cattle. The following results were obtained. 1. Splenic trabecular veins of bovine were collected from 3 chief Rami lienales: Rr. superior, inferior and V. polaris superior of the splenic veins, and the splenic parenchyma was ramified to 5-11 intralienal venous segments by the course of the trabecular veins. 2. Each one of the intralienal venous segments was dealt with 2-4 minute segments therefore, the splenic parenchyma was ramified from 13 minute segments in minimum to 35 minute segments in maximum. 3. The distribution of the veins in the spleen was divided into 7 types by the number of intralienal venous segment, and also was 15 kinds by collecting veins, Rr. superior et inferior and V. polaris superior. 4. The anastomosis was observed in the intralienal venous segments or minute segments. 5. Generally the splenic veins and arteries were like each other, but when observed minutely, they were unlike.

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Participation of COX-1 and COX-2 in the contractile effect of phenylephrine in prepubescent and old rats

  • Guevara-Balcazar, Gustavo;Ramirez-Sanchez, Israel;Mera-Jimenez, Elvia;Rubio-Gayosso, Ivan;Aguilar-Najera, Maria Eugenia;Castillo-Hernandez, Maria C.
    • The Korean Journal of Physiology and Pharmacology
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    • v.21 no.4
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    • pp.407-413
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    • 2017
  • Vascular reactivity can be influenced by the vascular region, animal age, and pathologies present. Prostaglandins (produced by COX-1 and COX-2) play an important role in the contractile response to phenylephrine in the abdominal aorta of young rats. Although these COXs are found in many tissues, their distribution and role in vascular reactivity are not clear. At a vascular level, they take part in the homeostasis functions involved in many physiological and pathologic processes (e.g., arterial pressure and inflammatory processes). The aim of this study was to analyze changes in the contractile response to phenylephrine of thoracic/abdominal aorta and the coronary artery during aging in rats. Three groups of rats were formed and sacrificed at three distinct ages: prepubescent, young and old adult. The results suggest that there is a higher participation of prostanoids in the contractile effect of phenylephrine in pre-pubescent rats, and a lower participation of the same in old rats. Contrarily, there seems to be a higher participation of prostanoids in the contractile response of the coronary artery of older than pre-pubescent rats. Considering that the changes in the expression of COX-2 were similar for the three age groups and the two tissues tested, and that expression of COX-1 is apparently greater in older rats, COX-1 and COX-2 may lose functionality in relation to their corresponding receptors during aging in rats.

Experimental Study on Cavo-Pulmonary Anastomosis (상공정맥-우폐동맥 문합에 관한 실험적 연구)

  • 양기민
    • Journal of Chest Surgery
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    • v.10 no.2
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    • pp.281-294
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    • 1977
  • Superior vena cava to pulmonary arterial shunting operation was made between the superior vena cava and the right pulmonary artery in the fashion of end-to-end anastomosis in 20 mongrel dogs. The experimental animals were divided into three group and blood flow in the superior vena cava was occluded for 20, 30 and 60 minutes respectively, and observations were made for the changes in caval pressure and cerebrospinal fluid pressure. And pathologic examinations were also performed. On occluding the caval blood flow, the superior vena caval pressure was sharply and immediately elevated from $103.5{\pm}19.8mmH_2O$ at thoracotomy to $556.4{\pm}86.lmmH_2O$ within 2 minutes to make its plateau thereafter, and the cerebrospinal fluid pressure followed closely the changes of the superior vena caval pressure in its level and pattern being elevated from $102.0{\pm}19.9mmH_2O$ to $490.5{\pm}79.9mmH_2O$. The drops of both the caval and cerebrospinal fluid pressures were definite and marked on opening the shunt flow through the anastomosis, but these postoperative pressures retained still higher ones above their levels measured at thoracotomy. The pathological examinations of the brain and the spinal cord were also performed in six animals. Characteristic changes uniformly seen in all area and in all animals were the findings of capillary congestion and perivascular edema. On the other hand, ischemic nerve cell changes were rather evident, revealing their degrees and extents being related to the prolongation of the time of caval occlusion which has followed by the sustained high pressures in both the superior vena and the cerebrospinal fluid. The experiment suggests the safety of this surgical procedure with minimal, if any, permanent damage as long as the occlusion of the caval blood flow is not prolonged beyond the expected.

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Trans-intervertebral Disc Approach of Superior Hypogastric Plexus Block for Pelvic Cancer Pain: A Retrospective Study (암성 골반통에 대한 경추간판적 상하복신경총 차단술의 효과)

  • Lee, Youn-Woo;Yoon, Duck-Mi;Lee, Gee-Moon;Han, Seung-Tak;Park, Hae-Jin
    • The Korean Journal of Pain
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    • v.13 no.2
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    • pp.202-207
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    • 2000
  • Background: Superior hypogastric plexus block has been advocated as a useful technique for the treatment of cancer related pelvic pain. The aim of this study was to evaluate the effect of neurolytic trans-intervertebrodiscal superior hypogastric plexus block for pelvic cancer pain. Methods: Twenty-eight patients with gynecologic, colorectal or genitourinary cancer who suffered intractable pain were studied. We performed superior hypogastric plexus block by trans-intervertebrodiscal approach at L5/S1 level under the C-arm fluoroscopic guide unilaterally or bilaterally. Ten ml of 100% dehydrated alcohol was injected through each needle. We evaluated the change of visual analog pain score (VAS; 0~100 mm) and daily dose of oral morphine sulphate at the time of pre-block and 7 days after the block. Results: Fourteen patients (50%) had satisfactory pain relief (VAS<30) while five patients (18%) had moderate pain control (VAS 30~60). The remaining nine patients (32%) had mild or little pain relief (VAS>60) and their daily oral morphine doses were above 160 mg. Additional pain control method may be needed for those patients who received high dose of opioid before neurolytic block. Conclusions: We conclude trans-intervertebrodiscal neurolytic superior hypogastric plexus block was effective in relieving pelvic cancer pain. Neurolytic block, earlier stage, may provide better effects for more comfortable life at the end stage for cancer patients.

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Ultrastructural Study on the Development of the Small Granule-Containing Cells in Superior Cervical Ganglion of Human Fetus (인태아 상경신경절내 소형의 과립함유세포에 관한 전자현미경적 연구)

  • Yoon, Jae-Rhyong;Min, Young-Don;Nam, Kwang-Il
    • Applied Microscopy
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    • v.26 no.3
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    • pp.349-367
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    • 1996
  • The development of small granule-containing cell in the superior cervical ganglion was studied by electron microscopic method in human fetuses ranging from 40 mm to 260 mm crown rump length (10 to 30 weeks of gestational age). At 40 mm fetus, the superior cervical ganglion was composed of clusters of undifferentiated cells, primitive neuroblasts, and unmyelinated nerve fibers together with blood vessels. At 90 mm fetus, the superior cervical ganglion consisted of neuroblasts, satellite cell, small granule-containing cells, and unmyelinated nerve fibers. Two morphological types of the small granule-containing cells in the superior cervical ganglion were first indentified at 90 mm fetus, but were rare. Type I granule-containing cell occurred in solitary and had long processes, whereas type II cells tend to appeared in clusters near the blood capillaries. The granule-containing cells were characterized by the presence of dense-cored vesicles ranging from $150{\sim}300nm$ in diameter in both the cell bodies and processes. Other organelles included abundant mitochondria, rough endoplasmic reticulum, neurotubules, and widely distributed ribosomes. The granule-containing cells had long processes similar to those found in principal ganglionic cells. They could be identified by their content in dense-cored vesicles. The small granule-containing cells increased somewhat in size and number with increase of fetal age. Synaptic contacts were first found on the solitary granule-containing cell at 150 mm fetus. Synaptic contacts between the soma and processes of type I granule-containing cells and preganglionic axon terminals were observed. In addition, synaptic junctions between the processes of granule-containing cells and presumed dendrite of postganglionic neuron were also observed from 150 mm onward. On the basis of these features type I granule-containing cells could be considered as interneurons. The clusters of type II granule-containing cells were located in the interstitial or subcapsular portions of the ganglion, and had short processes which ended in close relation to fenestrated capillaries. Therefore it may be infer that clusters of type II granule-containing cells have an endocrine function.

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In Vitro Screening for Antimicrobial Activity of Chitosans and Chitooligosaccharides, Aiming at Potential Uses in Functional Textiles

  • Fernandes, Joao C.;Tavaria, Freni K.;Fonseca, Susana C.;Ramos, Oscar S.;Pintado, Manuela E.;Malcata, F. Xavier
    • Journal of Microbiology and Biotechnology
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    • v.20 no.2
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    • pp.311-318
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    • 2010
  • Antimicrobial finishing of textiles has been found to be an economical way to prevent (or treat) skin disorders. Hence, this research effort was aimed at elucidating the relationship between the molecular weight (MW) of chitosan and its antimicrobial activity upon six dermal reference microorganisms, as well as the influence of the interactions with cotton fabrics on said activity. Using 3 chitosans with different MWs, as well as two chitooligosaccharide (COS) mixtures, a relevant antimicrobial effect was observed by 24 h for the six microorganisms tested; it was apparent that the antimicrobial effect is strongly dependent on the type of target microorganism and on the MW of chitosan - being higher for lower MW in the case of E. coli, K. pneumoniae, and P. aeruginosa, and the reverse in the case of both Gram-positive bacteria. Furthermore, a strong antifungal effect was detectable upon C. albicans, resembling the action over Gram-positive bacteria. Interactions with cotton fabric resulted in a loss of COS activity when compared with cultured media, relative to the effect over Gram-negative bacteria. However, no significant differences for the efficacy of all the 5 compounds were observed by 4 h. The three chitosans possessed a higher antimicrobial activity when impregnated onto the fabric, and presented a similar effect on both Gram-positive bacteria and yeast, in either matrix. Pseudomonas aeruginosa showed to be the most resistant microorganism to all five compounds.

Anterior inferior reconstruction plate on acute midshaft clavicle fvacture (쇄골 간부골절의 전하방 부착 재구성 금속판을 이용한 치료)

  • Kang, Jae-Do;Kim, Kwang-Ryul;Kim, Hyung-Chun;Lim, Moon-Sup;Kim, Seong-Hoon;Kweon, Jun-Hyung
    • Clinics in Shoulder and Elbow
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    • v.6 no.1
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    • pp.44-49
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    • 2003
  • Purpose: Many different operative technique of mid-shaft clavicle fracture have been reported. The aim of this prospective study was to compare the results of anterior or anterior-inferior plating with superior plating on the acute mid-shaft fracture of clavicle Materials and Methods: From February1997 to February 2002, thirty-eight consecutive open reduction and internal fixation with reconstruction plates were performed in thirty-eight patients. from August 1999, anterior or anterior-inferior plating was mainly used, prospectively. The duration of follow-up averaged 17 months (range,23 to 43 months). The mean age was 38 years old (range,21 to 57 years old) on anterior or anterior-inferior plating group and 35 years old (range,24 to 55 years old) on superior plating group. The physician progress note, VAS patient complement score, Roentgenogram and ASES score was evaluated. Results: Four patients were lost to follow-up. There was no statistical difference on mean radiological bone union time (8.7 weeks vs. 8.6 weeks) and ASES score (92 vs 94) at inferior and superior plating groups (P > 0.05). VAS patient complement score was very good or excellent on anterior or anterior-inferior group, average score was 1.1 (ranger,0 to 2) compare with superior plating group (P < 0.05). There were two cases of infection, 1 case of failed fixation on superior plating group and 1 case of delayed union on anterior inferior plating group. Conclusion: Anterior inferior plating on acute clavicle midshaft fracture results in excellent patient complement score compare with conventional superior reconstruction plate.