• Title/Summary/Keyword: Superior

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Synaptic Vesicle Protein 2 (SV2) Isoforms

  • Bandala, Cindy;Miliar-Garcia, A.;Mejia-Barradas, C.M.;Anaya-Ruiz, M.;Luna-Arias, J.P.;Bazan-Mendez, C.I.;Gomez-Lopez, M.;Juarez-Mendez, S.;Lara-Padilla, E.
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.10
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    • pp.5063-5067
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    • 2012
  • New molecular markers of cancer had emerged with novel applications in cancer prevention and therapeutics, including for breast cancer of unknown causes, which has a high impact on the health of women worldwide. The purpose of this research was to detemine protein and mRNA expression of synaptic vesicle 2 (SV2) isoforms A, B and C in breast cancer cell lines. Cultured cell lines MDA-MB-231, SKBR3, T47D were lysed and their protein and mRNA expression analyzed by real-time PCR and western blot technique, respectively. SV2A, B proteins were identified in non-tumor (MCF-10A) and tumor cell lines (MDA-MB-231 and T47D) while SV2C only was found in the T47D cell line. Furthermore, the genomic expression was consistent with protein expression for a such cell line, but in MDA-MB-231 there was no SV2B genomic expression, and the SV2C mRNA and protein were not found in the non tumoral cell line. These findings suggest a possible cellular transdifferentiation to neural character in breast cancer, of possible relevance to cancer development, and point to possible use of SV2 as molecular marker and a vehicle for cancer treatment with botulinum toxin.

An Analysis of Efficiency of Superior Appraisal Corporations Using DEA (DEA 모형을 이용한 우수감정평가법인의 효율성 분석)

  • Lee, Chan-Ho;Kim, Jong-Ki;Hwang, Soo-Jin;Jeon, Jin-Whan
    • The Journal of the Korea Contents Association
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    • v.10 no.12
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    • pp.290-299
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    • 2010
  • This study aims to evaluate the efficiency of superior appraisal corporations using DEA(Data Envelopment Analysis). DEA is known as a method for evaluating relative efficiency of organizations with multiple inputs and outputs. We used CCR-O and BCC-O DEA models to evaluate relative efficiency of superior appraisal corporations. Input variable is number of appraisers, output variables are total sales and net income. Total of 13 appraisal corporations in Korea were selected for this study, and the data were collected from financial reports for 2008 fiscal year. The result of this study is summarized as follows. First, the average of superior appraisal corporation's technical efficiency score is about 88.3% by applying CCR-O model. Second, the average of superior appraisal corporation's pure technical efficiency score is about 90% and scale efficiency score is about 98.2% by applying BCC-O model. According to the result of DEA, the cause of inefficiency is pure technical efficiency.

Rare Normal Variation Between Biceps Anchor and Superior Labrum - A Case Report - (상완 이두근 장두의 관절내 부착부위와 상부 관절와 순 간의 드문 변형 - 증례보고 -)

  • Kim, Yong-Ju;Jeong, Hoon;Ha, Jong-Kyoung;Lee, Kwan-Hee;Lee, Woo-Jin
    • Clinics in Shoulder and Elbow
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    • v.12 no.2
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    • pp.245-249
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    • 2009
  • Purpose: Labral lesions and its anatomic variants have been studied by several authors in the last decade. Buford complex and sublabral recess are most common variants. Their recognition is important in order to distinguish them from superior and anterior labral tear. Materials and Methods: We report one case of a 19-year-old female who was mistaken SLAP lesion for normal variant and was treated with arthroscopic surgery. Results: The arthroscopic finding shows rare normal variant of biceps anchor and superior labrum. The biceps long head tendon was inserted at superior labrum and supraspinatus tendon area. This finding was mistaken to SLAP lesion. Conclusion: We report rare normal variant of biceps anchor and superior labrum that was observed during arthroscopic surgery for SLAP lesion.

Usability Evaluation of Mobile Banking Applications in Digital Business as Emerging Economy

  • Hamid, Khalid;Iqbal, Muhammad Waseem;Muhammad, Hafiz Abdul Basit;Fuzail, Zubair;Ghafoor, Zahid Tabassum;Ahmad, Sana
    • International Journal of Computer Science & Network Security
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    • v.22 no.2
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    • pp.250-260
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    • 2022
  • Mobile Banking Applications (MBAPs) is one of the recent fads in mobile trading applications (Apps). MBAPs permit users to execute exchanges of money and many more whenever it might suit them; however, the primary issue for mobile banking Apps is usability. Hardly any investigation analyzes usability issues dependent on user's age, gender, exchanging accomplices, or experience. The purpose of this study is to determine the degree of usability issues, and experience of mobile banking users. The survey employs a quantitative method and performs user experiment on 240 participants with six different tasks on the application's interface. The post experiment survey is done with concerning participants. On the other hand, banking experts and Information Technology (IT) expert's group is also involved after the experiment. Expert's opinions about existing mobile banking Apps and suggestions for improving usability of MBAPs are collected through physical means (like questionnaire and interview) and online means like Google form. After that comparison of the opinions of users and experts about MBAPs is performed. The experimentation measures the tasks usability of various mobile banking apps with respect to its effectiveness, efficiency, trustfulness, learnability, memorability and satisfaction. The usability testing was led at different Universities and the outcomes acquired show that there are privacy and trust issues with their mobile banking apps. There is also a gap between users and experts which should be minimized by applying customized usability models, modes concept like other application software and also by adding complete features of banking in MBAPs. It will benefit mobile banking apps users, developers and usability engineers by providing user-friendly which are up to the mark of user's requirements.

Immunohistochemical studies on the relationship between pineal body and superior cervical ganglia of the Korean native goat (한국재래산양 송과체와 앞쪽목신경절의 관계규명을 위한 면역조직화학적 연구)

  • Lee, Heungshik S.;Lee, In-Se;Song, Seung-hoon;Yoon, Sung-tae;Hwang, In-koo;Lee, Choong-hyun
    • Korean Journal of Veterinary Research
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    • v.40 no.2
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    • pp.197-211
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    • 2000
  • The pineal body have been known to be affected by superior cervical ganglia, and most of its nerve fibers containing peptidergic neurotransmitters have been considered to be originated from this ganglia. To confirm this relationships, some peptidergic neurotransmitters were identified in both of pineal body and superior cervical ganglia of the Korean native goat, which were divided into two group; breeding season and non-breeding season. The localizations of two catecholamine-synthesizing enzymes; tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH), were investigated by immunohistochemistry in the superior cervical ganglia and the pineal body of adult Korean native goats. Substance P (SP), calcitonin gene-related peptide (CGRP), vasoactive intestinal polypeptide (VIP), neuropeptide Y (NPY) and galanin (GAL) were also identified in these organs by immunohistochemical and double immunofluorescent methods. In superior cervical ganglia, immunoreactivities for TH and DBH were confirmed in the same ganglion cells. The immunoreactivites for SP, VIP(only in male), NPY and GAL were identified in both of ganglion cell bodies and nerve fibers in the ganglia. CGRP immunoreactivity, however, was observed only in nerve fibers. Most NPY- and VIP-immunoreactive(IR) ganglion cells also contained TH. SP and TH were colocalized in the cell bodies, but not in the nerve fibers. TH immunoreactivity was shown in almost all of ganglion cells in the superior cervical ganglia. The immunoreactivity for NPY had some seasonal variation and was stronger in breeding season than in non-breeding season. In pineal body, lots of TH-IR fibers were observed throughout the parenchyma including the pineal stalk and most of them also contained DBH. SP- and NPY-IR fibers were also immunostained with TH or DBH. But a few SP- and NPY-IR fibers were not colocalized with TH or DBH. Exceptionally, a bipolar neuron-like cell was observed to be immunostained with NPY in the pineal body. A few CGRP and GAL-IR fibers were observed, while VIP-IR fibers were not present. It is concluded that most TH- and DBH-IR fibers as well as the peptidergic immunoreactive fibers of the pineal body might be originated from the superior cervical ganglia. Some peptidergic immunoreactive fibers, however, might be come from other regions of brain. We also suggest that NPY in pineal body plays a important role for pineal function. The seasonal variation of NPY immunoreactivity indicates that the synthesis and use of NPY may be different between in breeding and non-breeding seasons.

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Effects of Emotional Labor on Job Performance of Social Welfare Workers in Social Welfare Facilities : Focused on the Mediation Effect of Superior & Colleague Support (사회복지시설 사회복지사의 감정노동이 직무성과에 미치는 영향 : 상사와 동료지지 매개 효과 중심으로)

  • Kim, Su-Mok;Kim, Sang-Cheol
    • The Journal of the Korea Contents Association
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    • v.21 no.2
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    • pp.330-342
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    • 2021
  • The purpose of this study is to investigate the mediated effect of superior and co-worker support in the relationship between emotional labor and job performance of social workers working in social welfare facilities The research method is based on the results of a survey of 445 social workers working at social welfare facilities in the Seoul metropolitan area. The collected data are analyzed using SPSS V22.0 as follows. First, it had been shown that in the emotional labor of social workers, surface behavior had a negative effect on job performance, and inner action had a positive effect on job performance. Second, in the emotional labor of social workers, it was found that the surface act had a positive effect on the support of the superior and co-worker, and the inner act had a negative effect on the support of the superior and co-worker. Third, the superior & co-worker support of social workers had a positive effect on job performance. Fourth, superior & co-worker support in the relation to surface behavior and job performance in the emotional labor of social workers had a negative mediated effect. Superior & co-worker support in relation to inner act and job performance had revealed that it did not have a mediated effect.

Time-series Analysis of Baramarae Beach in Anmyeondo Using Aerial Photographs and Field Measurement Data (항공사진과 기준목 측정자료를 이용한 안면도 바람아래 해빈의 시계열 변화 분석)

  • KIM, Jang-soo;JANG, Dong-Ho
    • Journal of The Geomorphological Association of Korea
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    • v.18 no.2
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    • pp.39-51
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    • 2011
  • In this study, the shape of the Baramarae beach, Anmyeondo Area in West Coast of Korea and the changes in the sedimentation and erosion environment were analyzed in time series. As a result of the time series analysis of the shape of the Baramarae beach using aerial photographs from 1967 to 2009, the sand spit that developed in the southern part of Halmi Island was found to have had an EEN direction, but it was changed to a NNS direction, as reflected in the 2009 aerial photographs, as it gradually shifted to the west. In the onsite measurement, the H-3, H-4, H-5, and H-6 spots showed a superior sedimentation environment and the H-7, H-8, and H-9 spots showed a superior erosion environment. It was thus found that sedimentation is superior in the southwest beach and that erosion is superior in the northeast beach. The results in the spots between H-3 and H-6 indicate that the sand in the beach could not move to the northeast beach of Halmi Island due to the bank that had been established in the southwest beach of the island. On the other hand, it seems that superior erosion takes place in spots H-7 to H-9 in the northeast beach, where sand is not provided from the southwest beach of Halmi Island. It was found from the seasonal analysis that the season when superior sedimentation takes place in all the spots is autumn, and that the season when superior erosion takes place is summer. Superior sedimentation takes place in winter and spring in the southeast side and in summer in the northwest side.

A Study on the Angle between the Abdominal Aorta and the Superior Mesenteric Artery by 3D Image Reconstruction (3D 영상 재구성을 통한 복부대동맥과 상장간막동맥과의 각도에 관한 연구)

  • Kim, Young-Keun;Choi, Sung-Kwan
    • Journal of radiological science and technology
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    • v.26 no.1
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    • pp.63-70
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    • 2003
  • SMAS(Superior Mesenteric Artery Syndrome) is a disease caused by a chronic obstruction of the duodenum(transverse portion), which is hardly detectable. However, it is known that when the superior mesenteric artery and abdominal aorta form a narrow angle, that the transverse portion of the duodenum is pressed down between the superior mesenteric artery and the abdominal aorta, and that this can lead to obstruction of the duodenum. Measuring this angle is a complicated job using conventional angiography, and results often turns out to be inaccurate. In addition, no attempt has been made to determine the value of this angle in Koreans. In this study, we conducted abdominal CT angiography using MIP(maximum intensity projection) on patients with no clinical evidence of SMAS in order to determine the angle at which the superior mesenteric artery branches from the abdominal aorta by using PC based software(Rapidia ver. 1.2) for the image reconstruction. Accordingly, we found that the mean angle between the abdominal aorta and the superior mesenteric artery was $50.05{\pm}15.87^{\circ}$ on average, and that the angle in men($53.64{\pm}16.57^{\circ}$) is higher than in women($46.46{\pm}14.98^{\circ}$). We hope that the angles determined by our study will serve as an important indicator for detecting SMAS.

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