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Improvement of fibrosed scar tissue elongation using self-inflatable expander

  • Jung, Gyu-Un;Kim, Jin-Woo;Pang, Eun-Kyoung;Kim, Sun-Jong
    • The Journal of the Korean dental association
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    • v.54 no.7
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    • pp.501-512
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    • 2016
  • We evaluated a self-inflatable osmotic tissue expander for its utility in creating sufficient soft tissue elongation for primary closure after bone grafting. Six patients with alveolar defects who required vertical augmentation of >6 mm before implant placement were enrolled. All had more than three prior surgeries, and flap advancement for primary coverage was restricted by severely fibrosed scars. Expanders were inserted beneath the flap and fixed with a screw. After 4 weeks, expander removal and bone grafting were performed simultaneously. A vertical block autograft and guided bone regeneration and distraction osteogenesis were performed. Expansion was sufficient to cover the grafted area without additional periosteal incision. Complications included mucosal perforation and displacement of the expander. All augmentation procedures healed uneventfully and the osseous implants were successfully placed. The tissue expander may facilitate primary closure by increasing soft tissue volume. In our experience, this device is effective, rapid, and minimally invasive, especially in fibrous scar tissue.

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Performance Analysis of Space-Time Coded Spatial Multiplexing Systems with Rate Allocation and Power Control (전송률 할당 및 전력 제어를 갖는 시공간 블록 부호화한 공간 다중화 시스템의 성능 분석)

  • Na, Seung-Gun;Hwang, Hyeon-Chyeol;Kim, Seok-Ho;Choi, Sun-Ho;Kwak, Kyung-Sup
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.30 no.7A
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    • pp.568-577
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    • 2005
  • In this paper, we propose the transmission scheme for the space-time block coded spatial multiplexing systems that have adaptive rate and power allocation per each transmit antenna through the use of feedback information related to channel state. Simulation results show that the adaptive power and rate transmission scheme gain more than 4.5 dB over conventional equal-power and rate transmission scheme.

Comparison of Cortical Activation between Tactile Stimulation and Two-point Discrimination: An fMRI Case Study (촉각 자극과 두점식별 자극에 따른 뇌활성도 분석: fMRI 사례 연구)

  • Park, Ji-Won;Kim, Chung-Sun
    • The Journal of Korean Physical Therapy
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    • v.22 no.4
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    • pp.97-101
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    • 2010
  • Purpose: Sensory input is very important for proper performance of human. Two-point discrimination is the most widely used tactile sensory test. The purpose of this study was to find the changes in cortical activation patterns between tactile stimulation and two-point discrimination. Methods: Two healthy subjects participated in our study. fMRI scanning was done during 4 repeated blocks of tactile stimulation and two point discrimination of the right index finger tip. In one block, stimuli were repeated 10 times every three seconds. To determine the changes of cortical neurons during sensory input, intensity index was analyzed. Results: When tactile stimulation of the right index finger tip was completed, only contralateral primary somatosensory area was activated. In contrast, during two-point discrimination, both the primary somatosensory area and ipsilateral supplementary sensory area were activated. Conclusion: During two point discrimination, both primary somatosensory area and ipsilateral supplementary sensory area were activated. Therefore, two-point discrimination is required more complex and conscious activity than tactile stimulation.

Cytologic Features of Endodermal Sinus Tumor of Ovary in the Ascitic Fluid - Report of a Case - (난소에서 발생한 내배엽동 종양의 복수의 세포학적 소견 - 1례 보고 -)

  • Jeong, Eun-Sun;Kim, Young-Shin;Kang, Chang-Suk;Shim, Sang-In
    • The Korean Journal of Cytopathology
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    • v.6 no.2
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    • pp.204-208
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    • 1995
  • The cytologic findings of endodermal sinus tumor of the ovary are reported. The cytologic preperations were obtained from ascitic specimens. The findings on Papanicolaou-stained smears included a clean background and poorly preserved atypical cells loosely arranged in irregular or papillary groups. At high magnification, the cells had ill-defined and microvacuolated cytoplasms, with an increased nuclear-cytoplasmic ratio and prominent nucleoli. Hyaline globules characteristic of the alpha-fetoprotein (AFP)-synthesizing cells of endodermal sinus tumor were observed within the cells with periodic-acid-Schiff(PAS) stain. The presence of PAS-positive hyaline globules can be regarded, therefore, as a diagnostic clue to endodermal sinus tumor in an appropriate clinical setting and in the presence of AFP production. The cytologic findings in a cell block is important, in addition to smears, to obtain more diagnostic clues. A preliminary cytomorphologic diagnosis of this highly malignant tumor is valuable as a guide in planning further immunocytochemical and serologic studies.

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Dynamic Response Analysis of Caisson Structure by Acceleration Measurement (가속도 계측을 통한 항만시설용 케이슨 구조체의 동적응답 분석)

  • Lee, So-Young;Kim, Jeong-Tae;Kim, Heon-Tae;Park, Woo-Sun
    • Journal of Ocean Engineering and Technology
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    • v.23 no.1
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    • pp.114-121
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    • 2009
  • In this study, acceleration responses of caisson structures under various environmental conditions are experimentally examined as a basic study to develop the health assessment technique for harbor structures. To achieve the objective, three approaches are implemented. Firstly, a target caisson structure is selected and its small-scaled caisson is constructed in the laboratory. Secondly, a finite element model of the caisson is generated to identify dynamic responses of the baseline structure. Thirdly, experimental tests are performed on the caisson model to examine dynamic responses under various boundary conditions and impact locations. Four different boundary conditions, 'standing on concrete floor', 'standing on styrofoam block', 'standing on sand-mat' and 'hanging by crane', are considered and correlation coefficients of frequency response functions between four states are analyzed.

Improvement of In Vitro Development of Bovine Embryos in a Medium Containing Selenium

  • Lee, J.H.;Park, J.H.;Choi, K.M.;Im, K.S.;Jin, D.I
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.2
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    • pp.170-173
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    • 2001
  • The objective of this study was to investigate the effect of selenium (Se) on in vitro development of bovine embryos. In CR1BSA, FBS-free medium, the bovine embryos could not proceed past the developmental block more efficiently to morula stage than in chemically undefined media. Addition of glutathione precursor, cysteine, with $\beta$-mercaptoethanol did not improve the development in chemically defined medium and neither did glutathione alone. Exogenous selenium improved the embryonic development to the morula and blastocyst stages at 6 days post-insemination (dpi) significantly (67.1% vs 57.5%, p<0.05), and blastocyst stage at 8 dpi (30.1% vs 20.5%, p>0.05). These improvements might be induced by elevated glutathione peroxidase activity due to addition of Se, and a possible mechanism of selenium to elevate the activity of glutathione peroxidase is discussed.

Cancer Prevalence in Easter Island Population - 2006-2010

  • Rius, Eduardo Bravo;Armaroli, Pabla Yaikin;Contreras, Gustavo Saint-Pierre
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.5
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    • pp.3101-3103
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    • 2013
  • In Easter Island, population is composed by original habitants, the Rapa Nui culture and introduced people, mainly from continental Chile, who have a different ethnic origin. The aim of this research was to describe cancer frequency in resident population in Easter Island, and secondarily compare the findings with other islands of Polynesia and continental Chile. We reviewed the statistics of patients treated in Hanga Roa Hospital during the period 2006-2010, finding a total of 49 patients with cancer during the study. The most frequent cancers in Easter Island's people were breast cancer (8 cases), skin (8 cases), cervical (8 cases), lung (5 cases) and gastric (4 cases). According to gender, in females the most frequent cancer was breast, followed by skin and cervical, while in men, lung, prostate and hematopoietic cancers were the most frequent. Most cases of cervical cancer occurred in women of Rapa Nui ethnicity, while most skin cancers were found in non-Rapa Nui people. In case of the most common cancer in Easter Island, education (e.g. Papanicolaou and mammography screening) and prevention in the community (e.g. use sun block, avoid cigarettes) should be useful tools to reduce incidence.

A Study on Design Tendencies in Office Buildings of Public Institutions after Reinforcement of the Building Energy Performance Criteria in Korea (건물에너지성능기준 강화 이후 국내공공기관 업무용 건축물의 디자인경향)

  • Lee, Ah-Young
    • KIEAE Journal
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    • v.11 no.6
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    • pp.139-149
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    • 2011
  • This study focuses on design tendencies in office buildings of public institutions after tightening up Korea's building energy performance criteria. Important office design criteria and recommendations pay attention to the issues such as building orientation, greening buildings, building form, space and envelop by intensifying building energy performance related laws, government guidelines and evaluation systems. The design tendencies explored in this research are as follows. Office buildings mainly face south and have various types of indoor and roof green spaces not for ecological reasons but for the rest. Building depth becomes thinner and atria are inserted into office buildings to improve daylighting and natural ventilation. Building cores are located on north or west and east sides acting as buffer spaces to reduce heat loss and to block solar radiation. Office building envelop design includes various creative ideas to control or utilize solar energy as like three dimensional or double structured skin and window size variation to cope with the intensity of solar radiation. Further, solar energy generation systems are integrated with building component such as roofs, sun screens and windows. This study demonstrates that government's reinforcement of the building energy performance criteria drives the change in design methods and approach.

Metabolic Engineering of Deinococcus radiodurans for the Production of Phytoene

  • Jeong, Sun-Wook;Kang, Chang Keun;Choi, Yong Jun
    • Journal of Microbiology and Biotechnology
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    • v.28 no.10
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    • pp.1691-1699
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    • 2018
  • A metabolically-engineered Deinococcus radiodurans R1 strain capable of producing phytoene, a colorless $C_{40}$ carotenoid and a promising antioxidant, has been developed. To make this base strain, first, the crtI gene encoding phytoene desaturase was deleted to block the conversion of phytoene to other carotenoids such as lycopene and ${\gamma}$-carotene. This engineered strain produced $0.413{\pm}0.023mg/l$ of phytoene from 10 g/l of fructose. Further enhanced production of phytoene up to $4.46{\pm}0.19mg/l$ was achieved by overexpressing the crtB gene encoding phytoene synthase and the dxs genes encoding 1-deoxy-$\text\tiny{D}$-xylulose-5-phosphate synthase gene, and by deleting the crtD gene. High cell-density culture of our final engineered strain allowed production of $10.3{\pm}0.85mg/l$ of phytoene with the yield and productivity of $1.04{\pm}0.05mg/g$ and $0.143{\pm}0.012mg/l/h$, respectively, from 10 g/l of fructose. Furthermore, the antioxidant potential of phytoene produced by the final engineered strain was confirmed by in vitro DPPH radical-scavenging assay.

A Case Report of Herpes zoster with acute pain by Yongdamsagan-tang(longdanxiegan-tang) (용담사간탕(龍膽瀉肝湯)을 이용한 대상포진(帶狀疱疹)의 급성기(急性期) 통증(痛症)에 대한 치험(治驗) 1례(例))

  • Park Young-Jun;Park Joo-Han;Heo Geum-Jeong;Nam Chang-Gyu;Sun Jung-Ki;Koo Chang-Mo
    • The Journal of Internal Korean Medicine
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    • v.24 no.1
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    • pp.151-156
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    • 2003
  • Herpes zoster is a viral disease characterized by unilateral radicular pain and vesicular eruptions that are generally limited to the dermatome innervated by single spinal or cranial sensory ganglion. The disease causes severe pain and in particular, put elderly patients in great risks and further it develops postherpetic nenralgia. Nowadays western medicine use antiviral durg(ex: acyclovir), analgesics, nerve block and etc for treatment of herpes zoster and pain control, but the effect is not much satisfactory. A 73-year-old patient, admitted to our hospital because of severe migrain. Two days later, her illness was diagnosed as herpes zoster so we administrated Yongdamsagan-tang. After the six-day of treatment, all symptoms improved, especially headache was cleared since the four day long administration of Yongdamsagan-tang.

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