• 제목/요약/키워드: Sun:activity

검색결과 5,195건 처리시간 0.031초

Methanesulfonamide와 phenylhyazone 유도체의 살균활성에 대한 parameter focusing (Parameter focusing on the fungicidal activity of methanesulfonamide and phenylhydrazone derivatives)

  • 성낙도;김선영;최중권;옥환석
    • 농약과학회지
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    • 제3권2호
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    • pp.86-89
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    • 1999
  • 일련의 methanesulfonamide(Ia-Ig)와 phenylhydrazone(IIa-IIh) 유도체를 합성하고 식물성 병원균인 잿빛 곰팡이병균(BC: Botrytis cinerea), 고추 역병균(PC: Phytophthora capsici) 및 문고병균(RS: Rhizoctonia solani)에 대한 살균활성을 한천 희석법으로 측정하였다. 살균활성은 (I)보다 (II)가 다소 큰 영향을 미쳤으며 (I)과 (II) 모두 PC=BC>RS의 순서로 살균활성을 나타내었다. 다루어진 화합물 중에서 3-chlorophenyl 치환체, IIg가 PC균에 대하여 가장 강한 활성 ($pI_{50}=3.96$)을 보였다. 또한, parameter focusing을 통하여 검토된 살균활성에 미치는 요인들로는 Ovality, 극성 및 logP상수 등이었다.

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현대 대중과 역사 : 역사를 소재로 한 영상매체와 '리인액트먼트(Reenactment Activity)'를 중심으로 (Morden People and History : in terms of Historical Media and Reenactment Activity)

  • 박광순
    • 한국교육논총
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    • 제37권1호
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    • pp.19-32
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    • 2016
  • 최근 역사를 소재로 한 영상매체가 사람들의 관심을 많이 끌고 있다. 특히 역사드라마와 영화를 통해서 사람들은 역사에 친숙함을 느끼고 있다. 본고에서는 역사드라마와 영화의 특징을 간단히 보고, 그 한계와 비판점을 생각해보고자 한다. 또한 최근 소수의 사람들이지만 인기를 얻고 있는 리인액트먼트에 대해 간단히 알아보고 그 특징과 한계 및 비판점을 살펴보고 양 측의 관계에 대해 알아보고자 한다. 리인액트먼트를 우리말로 옮기면 '역사재현'이다. 역사재현이란 당대의 사건이나 생활상, 전투 등을 그대로 재현하는 것으로, 기본적으로 참여자는 여기에 관심이 있는 일반인들이 주를 이룬다. 역사교육에서 이러한 영상매체와 리인액트먼트 활동은 현대 대중의 관심 속에서 역사를 대중화하고 친근하게 만드는 역할을 하고 있다. 리인액트먼트는 역사드라마나 영화에 있어서 발생하는 몇 가지 제약을 해결하는데 우선적으로 비용적인 문제에서 큰 절감 효과를 노릴 수 있을 것이다.

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남녀 대학생의 캠퍼스웨어 이미지 평가와 선호도에 관한 연구 (The Image Evaluation and Preference of the Campus Wear of College Males and Females)

  • 황미선;이명희
    • 복식
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    • 제55권1호
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    • pp.139-150
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    • 2005
  • The purpose of this study was to find out differences of image evaluation according to perceiver's gender and clothing style, and to investigate the clothing preference according to the style of campus wear. Subjects were 340 college males and females in Seoul. The image of campus wear was divided into four dimensions: neatness, polishing, potency, and activity. Gender had significant influences on the perception of neatness, polishing, and potency. Males perceived the campus wear to be neater, more polished and potent than females. There were significant differences in evaluating neatness, polishing, potency, and activity according to campus wear style. The sweatshirt was estimated low in polishing and potency but high in activity. The T-shirt${\cdot}$short pants was estimated low in polishing and neatness but high in activity. The jumper was rated high in activity, and pants suit high in neatness, polishing, and potency, but it was estimated low in activity. The skirt suit was rated high in neatness and low in activity. The knit cardigan was perceived as polished image. College students preferred knit cardigan, one-piece dress, jumper, and pants suit, however, T-shirt${\cdot}$short pants was comparatively less preferred. Males estimated the knit cardigan to be more favorable than females. Characteristics of clothing image which influenced on preference of campus wear were different between males and females.

물오리나무 유래 고함량 Oregonin 추출방법 및 생리활성 연구 (Extraction Method and Physiological Activity of High Content Oregonin Derived from Plant of Alnus sibirica Fisch. ex Turcz)

  • 최선은
    • 생약학회지
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    • 제50권3호
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    • pp.165-174
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    • 2019
  • Oregonin is known as a representative active substance of plants of the Alnus species. In this study, we will show the results of establishing a method for extracting trace amounts of useful substances in plants. Additionally, a variety of physiological activity studies were conducted with extracts containing high content of useful substances. In this study, anti-oxidant, anti-inflammatory and anti-allergic activities of supercritical fluid residue 60% EtOH extracts of Alnus sibirica (ASCFR) were investigated in vitro. To explore anti-oxidant and anti-inflammatory characteristics of supercritical extract, DPPH radical scavenging, and ABTS radical scavenging activity, inhibition of nitric oxide production in LPS-stimulated RAW 264.7 cells and ${\beta}$-hexosaminidase release in IgE-stimulated RBL-2H3 cells were examined, respectively. Results showed a concentration-dependent increase in DPPH and ABTS radical scavenging activity. Cells stimulated with LPS produced more nitric oxide than normal control cells. However, cells treated with supercritical fluid residue 60% EtOH extract decreased production in a concentration-dependent manner. In anti-allergic activity studies, ASCFR showed concentration-dependentanti-allergic activity. Based on results and strong antioxidant activity, ASCFR has potential as basic research materials for development of therapeutic supplements-based medicines or functional cosmetics related to chronic inflammatory skin immunity diseases.

Tyrosinase inhibitory effect of gentisic acid derivatives

  • Lee, Yeon-Jung;Yoon, Sung-Il;Kim, Jung-Sun;Lee, Chi-Ho;Kim, Dae-Duk
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.294.2-295
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    • 2003
  • Gentisic acid, a skin-whitening agent, is known to possess tyrosinase inhibition activity. In order to develop an effective skin-whitening agent, hydroquinone derivatives in which the carboxylic acid moiety of gentisic acid was replaced with various functional groups, were selected and evaluated for their ability to inhibit tyrosinase activity as well as to inhibit melanin release. (omitted)

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Coumarins and a Polyacetylene from the Roots of Angelica purpuraefolia

  • Min, Byung-Sun
    • Natural Product Sciences
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    • 제12권3호
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    • pp.129-133
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    • 2006
  • Four coumarins (1-4) and one polyacetylene (5) were isolated from the roots of Anglica purpuraefolia Chung (Umbelliferae) through repeated column chromatography. Four coumarins, isoscopoletin (1), oxypeucedanin hydrate (2), arnottinin (3) and isokhellactone (4), and a polyacetylene, (+)-9(Z), 17-octadecadience-12,14-diyne-1,11,16-triol (5), were identified by spectroscopic analysis including two dimensional NMR and mass. These compounds were examined for their anti-complement activity against the classical pathway of the complement system. However, compounds 1-5 were inactive in this assay system.

으름 덩굴의 항균 성분 분리 및 함량분석

  • 황현익;이인순;김지은;문혜연
    • 한국생물공학회:학술대회논문집
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    • 한국생물공학회 2002년도 생물공학의 동향 (X)
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    • pp.253-256
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    • 2002
  • For the antimicrobial activity test, Akebia quinata DECAISNE stem were extract water and fractionate it with four solvents which had a different polarity, antimicribial activity were increased in oder of petroleum ether fraction = diethyl ether fraction ${\leq}$ n-buthanol fraction < ethyl acetate fraction < aqueous fraction. Water extracts of stems and fruits were showed inhibitory two species bacteria](Bacillus subtills KCTC 1021, Bacillus cereus KCTC 1012) from developing.

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Synthesis of 6-[2-(Benzoxazol-2-ylmethylamino )ethoxy]-1-Alkyl­1 H-lndole-2-Carboxylic Acid and Inhibitory Activity on $\beta$-Amyloid Aggregation

  • Lee, Sun-Mi;Jeon, Raok
    • Archives of Pharmacal Research
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    • 제28권11호
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    • pp.1219-1223
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    • 2005
  • 6-[2-(Benzoxazol-2-ylmethylamino)ethoxy]-1-alkyl-1H-indole-2-carboxylic acids were designed and synthesized as $\beta$-amyloid (A$\beta$) fibril assembly inhibitors. Their inhibitory activity on A$\beta$, aggregation was evaluated by thioflavin T assay although their activities were insignificant.