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식도암에서의 흉강경 식도적출술 치험 1례 (Thoracoscopic Esophagectomy for Esophageal Cancer -One Case Report-)

  • 정진용;연성모;박건;곽문섭;곽승수
    • Journal of Chest Surgery
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    • 제31권4호
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    • pp.418-421
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    • 1998
  • 흉강경수술은 최근 기구 및 술기의 급속한 발전으로 인하여 흉부의 간단한 수술 뿐만 아니라 비교적 복잡한 수술까지 적용될 정도로 그 활용이 광범위하게 되었다. 식도암에서의 흉강경을 이용한 식도적출술은 개흉술 및 개복술을 통한 식도적출술 후에 발생할 수 있는 합병증이 적다는 장점이 있으나, 이의 시술에는 많은 어려움이 뒤따르고 있으며 고도의 술기를 요한다. 최근 저자들은 하부식도에 발생한 편평상피세포암에 대해 흉강경을 이용한 식도적출술 및 식도위문합술을 시행하였다. 환자는 59세 남자로 연하곤란을 주소로 내원하였으며 식도조영술과 식도경검사에서 하부식도에 궤양성 종양을 보였으며 전산화단층촬영에서 주위장기으로의 침범이나 림프절종대는 없었다. 수술은 흉강경을 이용하여 흉부식도를 박리하고 개복술로 위관을 형성한 후 경부에서 식도위문합술을 시행하였다. 수술후 애성과 문합부위의 누출이 있었으나, 보존적 치료후 문합부위의 누출은 치유되어 양호한 상태로 퇴원하였으며 애성은 수술후 약 2개월후에 소실되었다.

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Effects of specific monoclonal antibodies to dense granular proteins on the invasion of Toxoplasma gondii in vitro and in vivo

  • Cha, Dong-Yeob;Song, In-Kwan;Lee, Gye-Sung;Hwang, Ok-Sun;Noh, HyungJun;Yeo, Seung-Dong;Shin, Dae-Whan;Lee, Young-Ha
    • Parasites, Hosts and Diseases
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    • 제39권3호
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    • pp.233-240
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    • 2001
  • Although some reports have been published on the protective effect of antibodies to Toxoplasma gondii surface membrane proteins, few address the inhibitory activity of antibodies to dense granular proteins (GRA proteins) . Therefore, we performed a series of experiments to evaluate the inhibitory effects of monoclonal antibodies (mAbs) to GRA proteins (GRA2, 28 kDa; GRA6, 32 kDa) and surface membrane protein (SAGI, 30 kDa) on the invasion of T. gondii tachyzoites. Passive immunization of mice with one of three mAbs following challenge with a lethal dose of tachyzoites significantly increased survival compared with results for mice treated with control ascites. The survival times of mice challenged with tachyzoties pretreated with anti-GRA6 or anti-SAG 1 mAb were significantly increased. Mice that received tachyzoties pretreated with both mAb and complement had longer survival times than those that received tachyzoites pretreated with mAb alone. Invasion of tachyzoites into fibroblasts and macrophages was significantly inhibited in the anti-GRA2, anti-GRA6 or anti-SAG 1 mAb pretreated group. Pretreatment with mAb and complement inhibited invasion of tachyzoites in both fibroblasts and macrophages. These results suggest that specific antibodies to dense-granule molecules may be useful for controlling infection with T. gondii.

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국소마취 수술환자의 불편감에 관한 연구 - 도구개발을 중심으로 - (A Study of Perceived Discomfort of The Patients Under Local Anesthesia - Centering Around the Development of Measures -)

  • 김경숙;김미자;박순미;백순영;이양숙;배상도;최정훈
    • 한국의료질향상학회지
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    • 제7권1호
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    • pp.6-17
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    • 2000
  • Background : This study was attempted to provide a basic information necessary for the development of measures evaluating perceived discomfort of the patients under local anesthesia and the developments of nursing intervention and nursing standard. Method : The study subjects were a convenience sample of 100 surgical patients under local anesthesia. The researcher visited the patients directly and explained the purpose of the study to them. Then they were asked to fill out questionnaires which were developed and structured by the researcher, under their prior permission. Out patient's data were collected at recovery room after operation. Results : Factor analysis on measures evaluating the patients under local anesthesia showed that the measures consisted of eight factors including "explanation", "humane treatment", "motion limitation", "pain", "no togetherness", "waiting", "the environment of operating room", and "unkindness". When analyzing each of the factors regarding their degree of contribution to perceived discomfort, it was found that "waiting" was highest in terms of the degree. According to general chara-cteristics of the sampled patients, the factor of "explanation" contributed to perceived discomfort more in male patients than female ones. Regarding parts of medical examination, the patients of otorhinolaryngology felt perceived discomfort most because of the factor of "pain". Conclusion : To relieve perceived discomfort the patients under local anesthesia require providing individually systematized nursing services which can reduce perceived discomfort according to each of the factors. In doing so, an unlimited attention and much effort should be given to realize CQI reaching the dimension of increase in comfort as well as decrease perceived discomfort.

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호스피스 병동과 일반병동의 말기암환자의 간호중재 비교 (A Comparison of Nursing Interventions with Terminal Cancer Patients in a Hospice Unit and General Units)

  • 노유자;한성숙;용진선;송민선;홍진의
    • 성인간호학회지
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    • 제14권4호
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    • pp.543-553
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    • 2002
  • Purpose: The purpose of the study was to compare symptoms, medical therapies, and nursing interventions with terminal cancer patients during the last four weeks of their lives in a hospice unit and general units. Method: For the descriptive survey study, data were collected by reviewing the medical records of 243 patients who died of terminal cancer at K hospital in Seoul. The data was analyzed by using Chi-square test and t-test. Result: The study findings are summarized as follows: There were higher frequencies in physical symptoms of constipation, itching sensation, pain, sleeping disturbance, soreness and dysuria for those patients in the hospice unit than those patient in general units. All emotional symptoms were recorded significantly higher for those patients in the hospice unit than those in general units. Regarding the major medical interventions, pain management was used more significantly for those patients in the hospice unit, but antibiotic therapy and resuscitation were used more significantly for those patients in general units. Conclusion: The hospice unit provided more comprehensive nursing interventions including psychological, spiritual, and family cares as well as physiological care for terminal cancer patients. The facts showed that those patients who would need hospice care in general units should be referred to the hospice unit at an appropriate time.

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