• 한국산학기술학회논문지
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• 제16권12호
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• pp.8728-8737
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• 2015

본 연구는 과거와 현재의 응급의료센터에 내원한 자살기도자들의 임상적 특징을 비교하여, 향후 환자 발생시 임상적인 중증도 예측과 자살예방 연구의 토대로 활용하기 위함이다. 저자는 1998년 1월부터 12월과 2013년 8월부터 2015년 7월에 원광대학교병원 응급의료센터에 내원한 자살기도자들의 임상적 특징의 변화를 후향적으로 비교 분석하였다. 발생률에서는 1998년도에는 남성(1.1:1)이 더 많았으나 2013-2015년도에는 여성(1.3:1)이 더 많았고, 1998년도에는 20대, 30대, 60대 이상에서 많았던 반면에 2013-2015년도에는 30-50대에 많았다. 자살 시도 방법에서 가장 많았던 것은 중독이었다(90.8%;1998, 72.7%;2013-2015). 자살기도로 인한 사망률은 1998년에 16.9%(남성 23.1%, 여성 10.0%)에서 2013-2015년에는 13.8%(남성 18.1%, 여성 10.5%)로 감소하였다. 전체 자살기도자(총 516명) 중 재발한 환자는 37명이었으며, 자살기도자 중 48.3%는 정신건강의학과에 협진을 의뢰하였으나, 재발한 환자 전수에서 정신질환을 가지고 있었고, 정신질환자가 일반인에 비해 자살률이 높기 때문에 앞으로 발생하는 모든 자살기도자는 정신건강의학과와의 협진과 지속적인 추적관찰이 필요하겠다.

• 대한응급의학회지
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• 제29권6호
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• pp.687-698
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• 2018

Objective: This study examined the characteristics of suicidal attempters, including pre-hospital patients and those who visited the emergency department. Methods: Suicidal attempters who had been reported to the 119 call center were selected between July 2015 and June 2016. Sex, age, place, methods of suicidal attempt, season, time, and suicide success rate were reviewed in the fire center records. Results: A total 961 suicide attempters were enrolled. Among them, 53.6% were males who had an approximately 2.6 times higher mortality than that of females (9.2%). The most preferred place to commit suicide was the home in both sexes (68.0% in male, 82.8% in female) and the most preferred methods was drug intoxication, particularly pesticide. The method with the highest mortality was hanging and the lowest was self-harm. The season of the highest mortality was spring. The success of suicide and the time variation were similar. Most of the un-transferred patients also selected fatal suicide attempts compared to transfer patients. Conclusion: Unlike previous studies, this study includes information on un-transferred patients. Overall, the probability of death was highest as more than 50 years men chose hanging as a method, which had an influence on the un-transferred patients group.

• 동의신경정신과학회지
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• 제34권3호
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• pp.213-234
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• 2023

Objectives: To investigate current status of randomized controlled clinical trial (RCT) registration for suicide attempters. Methods: The World Health Organization International Clinical Trials Registry Platform (WHO-ICTRP) was used to search for data using 'suicide' as a search term. All registration information of RCTs registered up to April 2023 were collected. Results: Among a total of 68 RCTs registered, the United States ranked the highest in terms of quantity in this field (n=30, 46.15%), whereas Asia had only six (8.82%). A total of 62 (91.18%) RCTs involved individual interventions, while nine (13.24%) RCTs involved group interventions. Among individual interventions, 11 (16.18%) and 54 (79.41%) RCTs were on pharmacotherapy and psychotherapy, respectively. Within psychotherapy, there were a total of 17 (25%) studies utilizing digital media, with cognitive behavioral therapy (CBT) via phone being the most common approach. Among non-digital media-based studies, CBT was used the most frequently (n=11, 16.18%), followed by attempted suicide short intervention program (n=6, 8.82%). There were no studies using interventions from East Asian traditional medicine, including Korean medicine (KM). The most frequently used main outcome was the Beck scale for suicidal ideation. Conclusions: Studies on suicide attempts in Asia, especially in South Korea, are very scarce. Despite vigorous psychotherapeutic research in this field, KM psychotherapy has not been used. Thus, KM clinical trial for suicide attempters might be planned in the future based on our findings.

• 생물정신의학
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• 제12권2호
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• pp.189-195
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• 2005

Objects:Some studies have suggested that brain-derived neurotrophic factor(BDNF), one of the most important neurotrophins, is involved in pathophysiology of depression and suicide. This study was performed to determine whether there is an abnormality in plasma BDNF concentration in suicidal attempters. Methods:The subjects were 71 suicidal attempters who visited emergency rooms in multi-medical centers. All subjects had been interviewed by using Structured Clinical Interview for DSM-IV(SCID), Hamilton Depression Rating Scale(HDRS), Young Mania Rating Scale(YMRS), and Positive And Negative Syndrome Scale(PANSS). The severity of the suicidal behavior was measured by Lethality of Suicide Attempt Rating Scale(LSARS) and Risk-Rescue Rating(RRR) system. Seventy-one age, sex, and diagnosis matched non-suicidal psychiatric patients who were consecutively admitted to a psychiatric ward during the same period recruited as psychiatric controls. They were drug-naive or drug-free at least more than 2 months. In addition, 80 healthy controls were randomly selected as normal controls. Plasma BDNF level was measured by the enzyme linked immunosorbent assay(ELISA) methods. Results:In overall F-test, differences of the plasma BDNF levels among the groups were statistically significant(F=20.226, p<0.001). In the multiple comparisons(Scheffe), while mean levels of plasma BDNF between normal controls and non-suicidal psychiatric patients were similar(p=0.984), the BDNF levels of suicidal attempters were lower than those of other two groups(p<0.001). LSARS and RRR did not reveal any significant correlations with BDNF levels in suicidal attempters. Conclusion:These results suggest that reduction of plasma BDNF level is related to suicidal behavior and BDNF level may be a biological marker of suicidal behavior.

• 정신신체의학
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• 제29권2호
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• pp.176-183
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• 2021

연구목적 응급실 기반 자살시도자 사후관리사업에 등록된 자살시도자의 인구학적 요인, 자살시도 패턴 및 정신건강의학과 병력 및 관리가 사후관리 프로그램 완수에 어떠한 영향을 끼치는지 알아보고자 하였다. 방 법 2018년 6월 1일부터 2021년 5월 31일까지 중앙대학교병원 응급실을 방문한 자살시도 환자 중 사례관리에 동의한 661명을 연구대상으로 하였다. 대상자는 응급실 퇴원 후 8주간의 사후관리 서비스 프로그램에 등록하여 관리를 받았다. 인구학적 요인, 자살시도 패턴, 정신건강의학과 병력 및 관리에 해당하는 요인들을 독립변인으로, 사후관리사업 프로그램의 완수 여부를 종속변인으로 두고, 위계적 로지스틱 회귀 분석을 시행하였다. 결 과 자살시도 패턴이 사후관리 사업 완수에 가장 큰 영향을 미치고, 인구학적 요인, 정신건강의학과 병력 및 관리 순으로 사후관리 사업 완료 여부에 영향을 미치는 것으로 나타났다. 자살시도자 사후관리사업 프로그램 완수자는 미완수자에 비해, 향후 자살계획을 가진 경우가 유의하게 많았고, 자살시도의 진정성이 강했으며, 과거자살시도력 또한 유의하게 높았다. 결 론 대상자들이 사후관리사업 프로그램을 완수하고 지역사회 서비스로 연계되도록 하기 위하여, 자살시도 패턴, 인구학적 요인, 정신건강의학과 병력에 대한 고려를 바탕으로 한 개별화된 접근이 필요하다.

• 보건행정학회지
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• 제29권1호
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• pp.1-3
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• 2019

Suicide is a major problem in Korean health care and a serious social problem. In Korea, 12,463 people (24.3 per 100,000) lost their lives due to suicide in 2017. Although the government has established three National Comprehensive Plan of Suicide Prevention (2004, 2009, 2016), and National Action Plan of Suicide Prevention (2018), the suicide rate is still high. The suicide rate of the elderly is especially high. This is due to the economic vulnerability of the elderly in Korea. Therefore, in order to prevent suicide in Korea, mental health care approach and social welfare approach should be integrated. The intervention of preventing suicide of suicide attempters should include social welfare services as well as mental health program and should be based on community. There are many health problems, including prevention of suicide, which can not be solved only by the efforts of health care. Many health problems are social problems and the integrated approach is needed to solve them. In order to solve many health care problems and improve health, integrated approach of health, social science, and humanities is needed.

• 정신신체의학
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• 제29권2호
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• pp.144-152
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• 2021

연구목적 본 연구는 응급실에 내원한 졸피뎀 음독 자살시도군과 다른 방법을 사용한 자살시도군을 비교하여 차이를 확인하고자 하였다. 방 법 2009년부터 2018년까지 응급실에 내원한 총2734명의 자살시도자를 대상으로 졸피뎀 음독 자살시도군, 졸피뎀 외 약물 음독 자살시도군, 비약물 자살시도군으로 분류하였으며, 세 군에 대하여 사회인구학적 특성, 자살시도와 관련된 임상적 특성들에 대해 교차분석과 회귀분석을 수행하였다. 결 과 졸피뎀 음독 자살시도군과 비약물적 자살시도군에서 차이를 보인 변수들에 대한 회귀 분석 결과에서, 안정제/수면제의 사용과 치명도가 낮거나 의도의 심각성이 높지 않은 경우가 졸피뎀 음독 자살시도의 발생과 연관성이 있었다. 유사한 특성을 보인 음독군 내에서도 안정제/수면제의 사용은 졸피뎀 음독 자살시도의 발생과 연관성이 있었다. 결 론 본 연구에서는 응급실에 내원한 졸피뎀 음독 자살시도군과 다른 방법을 사용한 자살시도군의 사회인구학적, 임상적 특성의 유의한 차이를 확인하였다. 이러한 결과는 추후 졸피뎀을 사용하는 것에 대한 약물적 치료를 계획하는데 도움이 될 수 있다.

• 생물정신의학
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• 제30권1호
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• pp.7-16
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• 2023

Objectives This study aimed to review the Korean Constitution articles 14 and 20 of the "Law on suicide prevention" and investigate public perceptions of specific improvements to suicide prevention policies using results from the Korean 2018 National Survey on Suicide. Methods The questionnaire was designed to analyzing the act restricts sharing of patient information between hospitals, making it difficult to track suicide attempts. The questionnaire was also designed to suggest further medical and normative criteria for objective judgment of continuous follow-up utilizing suicide risk evaluations and proportional principle review that consider patients' and medical staff's basic rights. Results This study identified the result of the 1500 respondents, 79.1% believed that Korea should allow suicide prevention management to be implemented without requiring individual consent to protect suicide attempters. Conclusions According the results, I propose the following criteria for policy improvement: use of anonymized information and non-profit research for technical and ethical considerations, access to medical information only for therapeutic purposes, and use of surgical severity assessment criteria appropriate for Korea.

• 생물정신의학
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• 제6권2호
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• pp.227-234
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• 1999

자살 시도군 231명, 환자 대조군 231명, 정상대조군 231명을 대상으로 혈청 콜레스테롤 농도를 측정하여 다음의 결과를 얻었다. 1) 자살 시도군이 환자대조군 혹은 정상대조군보다 혈청 콜레스테롤 농도의 유의한 저하를 보였다. 2) 진단별로는 우울증과 인격장애에서 자살 시도군이 환자대조군보다 콜레스테롤 농도의 유의한 저하를 보였으나, 정신분열병과 양극성 정동장애 조증형에선 차이가 없었다. 3) 자살 시도군의 남녀별로 비교시, 남자가 여자보다 콜레스테롤 농도의 유의한 저하를 보였으며, 진단별로는 우울증에서만 유의한 차이를 보였다. 4) 자살 시도군에서 낮은 콜레스테롤 농도는 심각한 자살 수행과 연관성이 있었다. 5) 자살 시도군에서 치료전에 비해 치료후 혈청 콜레스테롤 농도의 유의한 증가를 보였다. 본 연구의 결과는 자살 시도의 예측인자로서 혈청 콜레스테롤이 이용될 수 있음을 시사한다. 향후 콜레스테롤 농도에 미치는 변인들을 통제한 전향적 방법을 통해 원인적 측면에서 혈청 콜레스테롤 농도와 세로토닌, 인터루킨-2, 멜라토닌 간의 연관성에 관한 연구가 이루어져야 하겠다.

• 생물정신의학
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• 제22권4호
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• pp.187-194
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• 2015

Objectives To examine direct causes of attempted suicides, methods adopted to commit suicide, and psychiatric diagnoses among suicide attempters in South Korea. Methods A total of 1359 suicide attempters who had visited emergency department of 17 medical centers due to suicide attempt from May 2013 to Nov 2013 were interviewed using semi-structured questionnaires. Results Psychiatric symptoms were the most common cause of suicide attempts (62.2%), followed by interpersonal relationships (24.4%). Women attempted suicide more often for interpersonal reasons, whereas men were more likely to do so for financial and job-related reasons. Half of participants (55.8%) attempted suicide by drug intoxication, which was more prevalent among females and those who had previous history of psychiatric disease or previous suicide attempt. Men were more likely to use more lethal methods such as pesticide poisoning and gas inhalation than women. Pesticide poisoning was also prevalent among the elderly group and the rural population. Near ninety-five percent (94.5%) of participants received a psychiatric diagnosis : the most frequent diagnosis was depressive disorder. Conclusions This is the first nationwide study of cases of attempted suicide. When stratified by age groups, gender, urbanicity, living alone or not, presence of physical illness, previous psychiatric history, and previous suicide attempt, there were significant differences with respect to causes, methods of attempted suicides and psychiatric diagnoses of suicide attempters.