• 제목/요약/키워드: Substrate Stiffness

검색결과 58건 처리시간 0.025초

Polymer brush: a promising grafting approach to scaffolds for tissue engineering

  • Kim, Woonjung;Jung, Jongjin
    • BMB Reports
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    • 제49권12호
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    • pp.655-661
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    • 2016
  • Polymer brush is a soft material unit tethered covalently on the surface of scaffolds. It can induce functional and structural modification of a substrate's properties. Such surface coating approach has attracted special attentions in the fields of stem cell biology, tissue engineering, and regenerative medicine due to facile fabrication, usability of various polymers, extracellular matrix (ECM)-like structural features, and in vivo stability. Here, we summarized polymer brush-based grafting approaches comparing self-assembled monolayer (SAM)-based coating method, in addition to physico-chemical characterization techniques for surfaces such as wettability, stiffness/elasticity, roughness, and chemical composition that can affect cell adhesion, differentiation, and proliferation. We also reviewed recent advancements in cell biological applications of polymer brushes by focusing on stem cell differentiation and 3D supports/implants for tissue formation. Understanding cell behaviors on polymer brushes in the scale of nanometer length can contribute to systematic understandings of cellular responses at the interface of polymers and scaffolds and their simultaneous effects on cell behaviors for promising platform designs.

Modeling of Mechanical Behavior of Microcantilever due to Intrinsic Strain during Deposition

  • Kim Sang-Hyun;Mani Sathyanarayanan;Boyd James G. IV
    • Journal of Mechanical Science and Technology
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    • 제20권10호
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    • pp.1646-1652
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    • 2006
  • A model of mechanical behavior of microcantilever due to intrinsic strain during deposition of MEMS structures is derived. A linear ordinary differential equation is derived for the beam deflection as a function of the thickness of the deposited layer. Closed-form solutions are not possible, but numerical solutions are plotted for various dimensionless ratios of the beam stiffness, the intrinsic strain, and the elastic moduli of the substrate and deposited layer. This model predicts the deflection of the cantilever as a function of the deposited layer thickness and the residual stress distribution during deposition. The usefulness of these equations is that they are indicative of the real time behavior of the structures, i.e. it predicts the deflection of the beam continuously during deposition process.

Experimental and numerical disbond localization analyses of a notched plate repaired with a CFRP patch

  • Abderahmane, Sahli;Mokhtar, Bouziane M.;Smail, Benbarek;Wayne, Steven F.;Zhang, Liang;Belabbes, Bachir Bouiadjra;Boualem, Serier
    • Structural Engineering and Mechanics
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    • 제63권3호
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    • pp.361-370
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    • 2017
  • Through the use of finite element analysis and acoustic emission techniques we have evaluated the interfacial failure of a carbon fiber reinforced polymer (CFRP) repair patch on a notched aluminum substrate. The repair of cracks is a very common and widely used practice in the aeronautics field to extend the life of cracked sheet metal panels. The process consists of adhesively bonding a patch that encompasses the notched site to provide additional strength, thereby increasing life and avoiding costly replacements. The mechanical strength of the bonded joint relies mainly on the bonding of the adhesive to the plate and patch stiffness. Stress concentrations at crack tips promote disbonding of the composite patch from the substrate, consequently reducing the bonded area, which makes this a critical aspect of repair effectiveness. In this paper we examine patch disbonding by calculating the influence of notch tip stress on disbond area and verify computational results with acoustic emission (AE) measurements obtained from specimens subjected to uniaxial tension. The FE results showed that disbonding first occurs between the patch and the substrate close to free edge of the patch followed by failure around the tip of the notch, both highest stress regions. Experimental results revealed that cement adhesion at the aluminum interface was the limiting factor in patch performance. The patch did not appear to strengthen the aluminum substrate when measured by stress-strain due to early stage disbonding. Analysis of the AE signals provided insight to the disbond locations and progression at the metal-adhesive interface. Crack growth from the notch in the aluminum was not observed until the stress reached a critical level, an instant before final fracture, which was unaffected by the patch due to early stage disbonding. The FE model was further utilized to study the effects of patch fiber orientation and increased adhesive strength. The model revealed that the effectiveness of patch repairs is strongly dependent upon the combined interactions of adhesive bond strength and fiber orientation.

LCD 로봇 주요 프레임에 대한 설계 최적화 및 용접부 수명평가 (Design Optimization and Endurance Assessment of Weld Area for LCD Robot Frame)

  • 한성욱;강윤식;김태현;김상현
    • 대한기계학회논문집 C: 기술과 교육
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    • 제5권2호
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    • pp.89-95
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    • 2017
  • 제품을 개발하는데 있어서 경량화와 원가절감이라는 두가지 요소는 가장 중요한 화두이다. 특히 대형 LCD 로봇은 최대 $3{\times}3m$ 이상의 글라스를 7m 높이까지 상하, 전후로의 직선운동과 선회축을 중심으로한 회전운동을 하면서 작업공정간 이송을 가능케 하는 대형 구조물이다. 따라서 지나치게 무거울 경우에는 클린룸내 설치에 문제가 있을 수 있고 반송물의 정확한 이송을 위하여는 고강성이 요구되며 대량 생산을 위한 연속작업을 충분히 감당할 수 있는 내구강도를 확보하여야 한다. 따라서 경량화, 고강성, 고강도 제품에 대한 요구는 갈수록 증가하고 있다. 현재 개발되고 있는 11 세대 대형 LCD 승강프레임은 이러한 요구조건을 충족하기 위하여 최적설계 기법을 적용하여 기존 제품 대비 경량화와 고강성 요구조건을 만족하였으며 용접부에 대한 상세 수명평가로 내구강도에 대한 신뢰성을 확보하였다.

Analytical and experimental investigation of stepped piezoelectric energy harvester

  • Deepesh, Upadrashta;Li, Xiangyang;Yang, Yaowen
    • Smart Structures and Systems
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    • 제26권6호
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    • pp.681-692
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    • 2020
  • Conventional Piezoelectric Energy Harvesters (CPEH) have been extensively studied for maximizing their electrical output through material selection, geometric and structural optimization, and adoption of efficient interface circuits. In this paper, the performance of Stepped Piezoelectric Energy Harvester (SPEH) under harmonic base excitation is studied analytically, numerically and experimentally. The motivation is to compare the energy harvesting performance of CPEH and SPEHs with the same characteristics (resonant frequency). The results of this study challenge the notion of achieving higher voltage and power output through incorporation of geometric discontinuities such as step sections in the harvester beams. A CPEH consists of substrate material with a patch of piezoelectric material bonded over it and a tip mass at the free end to tune the resonant frequency. A SPEH is designed by introducing a step section near the root of substrate beam to induce higher dynamic strain for maximizing the electrical output. The incorporation of step section reduces the stiffness and consequently, a lower tip mass is used with SPEH to match the resonant frequency to that of CPEH. Moreover, the electromechanical coupling coefficient, forcing function and damping are significantly influenced because of the inclusion of step section, which consequently affects harvester's output. Three different configurations of SPEHs characterized by the same resonant frequency as that of CPEH are designed and analyzed using linear electromechanical model and their performances are compared. The variation of strain on the harvester beams is obtained using finite element analysis. The prototypes of CPEH and SPEHs are fabricated and experimentally tested. It is shown that the power output from SPEHs is lower than the CPEH. When the prototypes with resonant frequencies in the range of 56-56.5 Hz are tested at 1 m/s2, three SPEHs generate power output of 482 μW, 424 μW and 228 μW when compared with 674 μW from CPEH. It is concluded that the advantage of increasing dynamic strain using step section is negated by increase in damping and decrease in forcing function. However, SPEHs show slightly better performance in terms of specific power and thus making them suitable for practical scenarios where the ratio of power to system mass is critical.

Influence of flexoelectricity on bending of piezoelectric perforated FG composite nanobeam rested on elastic foundation

  • Ali Alnujaie;Alaa A. Abdelrahman;Abdulrahman M. Alanasari;Mohamed A. Eltaher
    • Steel and Composite Structures
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    • 제49권4호
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    • pp.361-380
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    • 2023
  • A size dependent bending behavior of piezoelectrical flexoelectric layered perforated functionally graded (FG) composite nanobeam rested on an elastic foundation is investigated analytically. The composite beam is composed of regularly cutout FG core and two piezoelectric face sheets. The material characteristics is graded through the core thickness by power law function. Regular squared cutout perforation pattern is considered and closed forms of the equivalent stiffness parameters are derived. The modified nonlocal strain gradient elasticity theory is employed to incorporate the microstructure as well as nonlocality effects into governing equations. The Winkler as well as the Pasternak elastic foundation models are employed to simulate the substrate medium. The Hamiltonian approach is adopted to derive the governing equilibrium equation including piezoelectric and flexoelectric effects. Analytical solution methodology is developed to derive closed forms for the size dependent electromechanical as well as mechanical bending profiles. The model is verified by comparing the obtained results with the available corresponding results in the literature. To demonstrate the applicability of the developed procedure, parametric studies are performed to explore influences of gradation index, elastic medium parameters, flexoelectric and piezoelectric parameters, geometrical and peroration parameters, and material parameters on the size dependent bending behavior of piezoelectrically layered PFG nanobeams. Results obtained revealed the significant effects both the flexoelectric and piezoelectric parameters on the bending behavior of the piezoelectric composite nanobeams. These parameters could be controlled to improve the size dependent electromechanical as well as mechanical behaviors. The obtained results and the developed procedure are helpful for design and manufacturing of MEMS and NEMS.

초속경 라텍스개질콘크리트로 덧씌우기 및 보수된 철근콘크리트보의 보강효과 (Strengthen Effect of RC Beam Overlaid or Repaired by VES-LMC)

  • 최성용;윤경구;최승식
    • 콘크리트학회논문집
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    • 제20권4호
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    • pp.423-430
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    • 2008
  • 최근 들어 고속도로를 중심으로 하여 교량상판 보수재료로 초속경 라텍스개질콘크리트 (Very-Early Strength Latex-Modified Concrete : 이하 VES-LMC)가 개발되어 이용되고 있고, 그 활용 빈도가 커지고 있다. 이는 VES-LMC의 특징상 보수 후 3시간 만에 교통개방이 가능하며, 라텍스 첨가로 기존의 보수재료가 갖는 장기 내구성의 문제를 해결하였기 때문이다. 그러나 위와 같은 장점으로 보수 보강 재료로 사용되고 있는 VES-LMC에 대한 구조적인 연구에 대해서는 미비한 상태이다. 본 연구에서는 VES-LMC를 기존보의 덧씌우기 형태와 열화된 콘크리트의 보수 형태로 나누어 시험체를 제작하고, 4점 휨 실험을 수행하여 휨 거동 및 신 구 콘크리트의 부착 특성과 균열 진전 양상, 보수 보강효과를 확인하고자 하였다. 그 결과 보수 보강두께가 증가함에 따라 보수 보강효과가 증가하는 경향을 보였으며 이는 강성이 증가하여 휨에 대한 저항 능력이 증대되는 것을 확인하였다. 보수 시험체의 경우 철근의 피복두께 이상으로 보수 되었을 경우 강성이 최대 40% 이상 증가 되는 결과는 얻을 수 있었으나 80 mm와 120 mm의 경우 그 값이 비슷한 양상을 보여 보강 두께 선정 시 고려되어야 할 요소라 판단된다. 계면거동을 확인한 결과 보수 및 보강 시험체 모두 계면에서의 상대 변위량이 감소되는 것을 확인하였으며, 두 재료가 비교적 일체로 거동하는 것을 확인하였다.

초속경 라텍스개질 콘크리트로 보강된 RC보의 비선형 휨해석 (Nonlinear Flexural Analysis of RC Beam Rehabilitated by Very-Early Strength Latex-Modified Concrete)

  • 최성용;윤경구;김용빈;강문식
    • 한국산학기술학회논문지
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    • 제11권11호
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    • pp.4635-4642
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    • 2010
  • 라텍스로 개질된 콘크리트는 높은 휨강도 뿐만아니라 부착강도 및 투수저항성이 좋은 재료특성을 제공한다. 이러한 이점을 활용한 초속경 라텍스개질 콘크리트(VES-LMC)에 관련된 연구결과는 재료에 관한 것이 대부분으로, VES-LMC로 덧씌우기 보강된 RC 보의 부착 경계면 거동특성에 대한 체계적인 연구는 미진하다. 따라서 본 논문에서는 VES-LMC로 보강된 철근콘크리트 보의 비선형 휨 거동에 대한 특성을 알아보고자 ABAQUS를 매개변수 연구를 수행한 결과 다음과 같은 결과를 얻을 수 있었다. 비선형 휨 해석을 위하여 본 논문에 적용된 모델의 적합성 여부를 확인한 결과 실험값과 비교적 유사한 경향을 보이는 것을 확인 할 수 있었다. 두께가 증가함에 따라 최대 저항강도가 증가하는 경향을 보여주었으며, 또한 강성 이 증가하여 내하력이 증진되는 결과를 확인할 수 있었다. 부착강도를 변수로 해석한 결과, 전단강도가 증가함에 따라 휨 저항능력이 향상되는 결과를 확인 하였으며, 두 이질재료의 부착능력이 구조물의 내하력에 지배적인 인자로 작용하는 것을 알 수 있었다.

무선 센서용 표면탄성파의 3 차원 모델링 (3D modeling of a surface acoustic wave for wireless sensors)

  • 트렌 녹 쿵;정귀상
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2009년도 추계학술대회 논문집
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    • pp.111-111
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    • 2009
  • In this work, we discuss simulation of surface acoustic wave device using Comsol Multiphysics. The structure SAW device based on piezoelectric thin film aluminum-nitride (AlN) on silicon was simulated. Some parameters of SAW device such as surface velocity, displacement of piezoelectric thin film were evaluated by software. Many modes and shapes of wave are also discussed in this paper. For evaluation physical parameters of AlN piezoelectric layer, the SAW resonator was modeled and simulation results were also compared with experiment results. we simulated arid evaluated the surface Rayleigh wave of AlN thin film on silicon substrate. Results simulation and experiment showed the surface velocity of AlN thin film was about 5200 m/s and shape of surface wave was also displayed. This paper has also proposed as method to study SAW characteristic of piezoelectric thin film and found out measurement values accurately of film such as stiffness matrix, piezoelectric matrix. These values are very important in calculation and design SAW device or MEMS device based on AlN piezoelectric layer.

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Plasma Surface Modification of Patterned Polyurethane Acrylate (PUA) Film for Biomedical Applications

  • Yun, Young-Shik;Kang, Eun-Hye;Yun, In-Sik;Kim, Yong-Oock;Yeo, Jong-Souk
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2015년도 제49회 하계 정기학술대회 초록집
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    • pp.223.2-223.2
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    • 2015
  • Polyurethane acrylate (PUA) has been introduced to utilize as a mold material for sub-100 nm lithography as it provides advantages of stiffness for nanostructure formation, short curing time, flexibility for large area replication and transparency for relevant biomedical applications. Due to the ability to fabricate nanostructures on PUA, there have been many efforts to mimic extracellular matrix (ECM) using PUA especially in a field of tissue engineering. It has been demonstrated that PUA is useful for investigating the nanoscale-topographical effects on cell behavior in vitro such as cell attachment, spreading on a substrate, proliferation, and stem cell fate with various types of nanostructures. In this study, we have conducted surface modification of PUA films with micro/nanostructures on their surfaces using plasma treatment. In general, it is widely known that the plasma treated surface increases cell attachment as well as adsorption of ECM materials such as fibronectin, collagen and gelatin. Effect of plasma treatment on PUA especially with surface of micro/nanostructures needs to be understood further for its biomedical applications. We have evaluated the modified PUA film as a culture platform using adipose derived stem cells. Then, the behavior of stem cells and the level of adsorbed protein have been analyzed.

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