• Title/Summary/Keyword: Subgroup method

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Effectiveness of Exercise Therapy on Physical Function in Patients With Ankylosing Spondylitis: Systemic Review and Meta-Analysis (강직성 척추염 환자의 신체기능에 대한 운동치료의 효과: 체계적 고찰과 메타분석)

  • Shim, Jae-Hun
    • Physical Therapy Korea
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    • v.16 no.3
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    • pp.50-59
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    • 2009
  • The aim of the study was to evaluate the effectiveness of exercise therapy on physical function of patients with anklyosing spondylitis (AS) through the systemic review and meta-analysis. The 54 studies were identified from computerized search of published researches on PubMed, Embase, CINAHL, PEDro, KISS, KERIS database until February, 2008 and review of reference lists. The main search terms were the combination "ankylosing spondylitis", "exercise", "spondyloarthropathy and exercise", "ankylosing spondylitis and physical therapy". The subgroup analysis was performed by the publication year, quality score, type of disease, content of intervention, intervention provider, type of intervention, method of intervention, intervention period and the point of outcome measured. Two reviewers independently selected trials for inclusion, assessed the quality and extracted the data. The result was as follows: The 10 trials were eligible for inclusion criteria, then the systematic review and meta-analysis was assessed on effectiveness of exercise therapy. The meta-analysis of 10 studies based on the random effect model showed that the exercise therapy was beneficial in treating the diseases (effect size .55; 95% confidence interval -.3.75~.61). The findings suggest that the exercise therapy would be appropriate to manage the physical function of AS with evidence based on Meta-analysis. Therefore, the exercise therapy supervised by physical therapist should be recognized as the essential approach to manage the AS and necessarily recommended to improve physical function.

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Improvement of Okamoto-Uchiyama Probabilistic Public Key Cryptosystem (Okamoto-Uchiyama 확률 공개키 암호 방식의 효율성 개선)

  • Choi, Duk-Hwan;Kim, Hyun-Jue;Choi, Seung-Bok;Won, Dong-Ho
    • Journal of KIISE:Information Networking
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    • v.29 no.4
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    • pp.346-351
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    • 2002
  • We improve a new probabilistic public key cryptosystem, in which the one wav function was defined only on the discrete logarithmic functions, proposed by Okamoto and Uchiyama. The plaintexts are calculated from the modular product of two these functions, one of which has a fixed value depending on a given public key. The improvement is achieved by a well-chosen public key assuming an unit element 1 as the fixed function value. Because it is possible to reduce the number of operations at the decryption. Also the concrete method for a public key of our improved scheme is suggested.

An Approach of Product Placement and Path Evaluation Using Social Network Subgroup: Focusing on Shopping Basket Data Analysis (사회연결망 서브그룹을 통한 소매점 상품배치 및 동선 평가: 장바구니 데이터 분석을 중심으로)

  • Yoon, Han-Seong
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.17 no.4
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    • pp.109-120
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    • 2021
  • Despite the growing online exposure of retailes, offline retail channels still outperform online channels in the total retail volume of some countries. There is much interest in the physical layout plans of retail stores to expand sales. Product placement that have a large impact on customer purchasing behavior at offline retailers influences customer movement and sales volume. But in many cases, each retailer relies on unsystematic and autonomous product placement. When multiple products are sold with one purchase, the customer's movement for shopping may be evaluated in terms of customer efficiency and additional impulse purchase. In this paper, the social network is applied to sales data of a retail store and the result is used for evaluation of product placement and customer path. The frequent sales product composition was identified using k-core from sales data in the form of shopping baskets. The location was checked for the identified compositions of products, the spatial variance was measured and the customer's path was identified. With these results, the store arrangement of products was evaluated with appropriate improvement directions. The analysis method of this paper can be an alternative analysis approach for better layout of retail stores.

Effect of sintering programs and surface treatments on monolithic zirconia

  • Seren Nur Dokuzlu ;Meryem Gulce Subasi
    • The Journal of Advanced Prosthodontics
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    • v.16 no.1
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    • pp.25-37
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    • 2024
  • PURPOSE. To investigate the effect of sintering programs and surface treatments on surface properties, phase transformation and flexural strength of monolithic zirconia. MATERIALS AND METHODS. Zirconia specimens were sintered using three distinct sintering programs [classic (C), speed (S), and superspeed (SS)] (n = 56, each). One sample from each group underwent scanning electron microscopy (SEM) and grain size analysis following sintering. Remaining samples were divided into five subgroups (n = 11) based on the surface treatments: control (CL), polish (P), glaze (G), grind + polish (GP), and grind + glaze (GG). One sample from each subgroup underwent SEM analysis. Remaining samples were thermally aged. Monoclinic phase volume, surface roughness, and three-point flexural strength were measured. Monoclinic phase volume and surface roughness were analyzed by Kruskal-Wallis and Dunn tests. Flexural strength was analyzed by two-way ANOVA and Weibull analysis. The relationships among the groups were analyzed using Spearman's correlation analysis. RESULTS. Sintering program, surface treatment, and sintering × surface treatment (P ≤ .010) affected the monoclinic phase volume, whereas the type of surface treatment and sintering × surface treatment affected the surface roughness (P < .001). Type of sintering program or surface treatment did not affect the flexural strength. Weibull analysis revealed no significant differences between the m and σo values. Monoclinic phase volume was positively correlated with surface roughness in the SGG and SSP groups. CONCLUSION. After sintering monolithic zirconia in each of the three sintering programs, each of the surface treatments can be used. However, for surface quality and aging resistance, G or GG can be recommended as a surface finishing method.

Development of multigroup cross section library generation system TPAMS

  • Lili Wen;Haicheng Wu;Ying Chen;Xiaoming Chai;Xiaofei Wu;Xiaolan Tu;Yuan Liu
    • Nuclear Engineering and Technology
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    • v.56 no.6
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    • pp.2208-2219
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    • 2024
  • Kylin-2 is an advanced neutronics lattice code, developed by Nuclear Power Institute of China. High-precision multigroup cross section library is need for KYLIN-2 to carry out simulation of current pressurized water reactor (PWR) and advanced reactor. In this paper a multigroup cross section library generation system named TPAMS was developed, the methods in TPAMS dealing with resonance data such as subgroup parameters, lambda factor, resonance integral were discussed. Moreover, the depletion chain simplification method was studied. TPAMS can produce multigroup library in binary and ASIIC formats, including detailed data contents for resonance, transport and depletion calculations. A multigroup cross section library has been generated for KYLIN-2 based on TPAMS system. The multigroup cross section library was verified through the analysis of various criticality and burnup benchmarks, the values of multiplication factor and isotope density were compared with the experiment data. Numerical results demonstrate the accuracy of the multigroup cross section library and the reliability of the multigroup cross section library generation system TPAMS.

Association between Pax8-PPARγ1 Rearrangement and Follicular Thyroid Cancer: a Meta-Analysis

  • Li, Hang-Yu;Xie, Zhi-Hao;Xu, Cong-Hui;Pu, Mei-Ling;Chen, Zi-Yan;Yu, Miao;Wang, Heng-Shu;Zhou, Chen-Ming;Pu, Chao-Yu;Liu, Wei
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.9
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    • pp.4247-4250
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    • 2016
  • Background: Pax8 and peroxisome proliferator-activated receptor gamma 1 gene (Pax8-$PPAR{\gamma}1$) are important factors in tumors. Several studies have suggested that follicular thyroid cancer may arise from Pax8- $PPAR{\gamma}1$ rearrangement. In order to have a better understanding of the association between Pax8-$PPAR{\gamma}1$ rearrangement and follicular thyroid cancer, we conducted the presenmt meta-analysis. Materials and Methods: The information was extracted from PubMed, EMBASE and Web of Science. Statistic analysis was performed with Stata12.0 software. Odds ratios (ORs) were calculated using a fixed-effects model. We also performed heterogeneity and publication bias analyses. Results: Nine studies including 198 follicular thyroid cancer patients and 268 controls were considered eligible. The frequency of Pax8-$PPAR{\gamma}1$ rearrangement was significantly higher in the follicular thyroid cancer group than in the control group, with a pooled OR of 6.63 (95%CI=3.50-12.7). In addition, through subgroup analysis, the OR between Pax8-$PPAR{\gamma}1$ rearrangement and follicular thyroid cancer was 6.04 (95%CI = 3.18-11.5) when using benign tumor tissues as controls. The OR for the method subgroup was 9.99 (95% CI =4.86-20.5) in the RT-PCR. Conclusions: The final results demonstrated that Pax8-$PPAR{\gamma}1$ rearrangement has significant association with follicular thyroid cancer.

Analysis of the Process Capability Index According to the Sample Size of Multi-Measurement (다측정 표본크기에 대한 공정능력지수 분석)

  • Lee, Do-Kyung
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.42 no.1
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    • pp.151-157
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    • 2019
  • This study is about the process capability index (PCI). In this study, we introduce several indices including the index $C_{PR}$ and present the characteristics of the $C_{PR}$ as well as its validity. The difference between the other indices and the $C_{PR}$ is the way we use to estimate the standard deviation. Calculating the index, most indices use sample standard deviation while the index $C_{PR}$ uses range R. The sample standard deviation is generally a better estimator than the range R. But in the case of the panel process, the $C_{PR}$ has more consistency than the other indices at the point of non-conforming ratio which is an important term in quality control. The reason why the $C_{PR}$ using the range has better consistency is explained by introducing the concept of 'flatness ratio'. At least one million cells are present in one panel, so we can't inspect all of them. In estimating the PCI, it is necessary to consider the inspection cost together with the consistency. Even though we want smaller sample size at the point of inspection cost, the small sample size makes the PCI unreliable. There is 'trade off' between the inspection cost and the accuracy of the PCI. Therefore, we should obtain as large a sample size as possible under the allowed inspection cost. In order for $C_{PR}$ to be used throughout the industry, it is necessary to analyze the characteristics of the $C_{PR}$. Because the $C_{PR}$ is a kind of index including subgroup concept, the analysis should be done at the point of sample size of the subgroup. We present numerical analysis results of $C_{PR}$ by the data from the random number generating method. In this study, we also show the difference between the $C_{PR}$ using the range and the $C_P$ which is a representative index using the sample standard deviation. Regression analysis was used for the numerical analysis of the sample data. In addition, residual analysis and equal variance analysis was also conducted.

Systematic Review and Meta-Analysis of Antibiotic-Impregnated Shunt Catheters on Anti-Infective Effect of Hydrocephalus Shunt

  • Zhou, Wen-xiu;Hou, Wen-bo;Zhou, Chao;Yin, Yu-xia;Lu, Shou-tao;Liu, Guang;Fang, Yi;Li, Jian-wen;Wang, Yan;Liu, Ai-hua;Zhang, Hai-jun
    • Journal of Korean Neurosurgical Society
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    • v.64 no.2
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    • pp.297-308
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    • 2021
  • Objective : Shunt infection is a common complication while treating hydrocephalus. The antibiotic-impregnated shunt catheter (AISC) was designed to reduce shunt infection rate. A meta-analysis was conducted to study the effectiveness of AISCs in reduction of shunt infection in terms of age, follow-up time and high-risk patient population. Methods : This study reviewed literature from three databases including PubMed, EMBASE, and Cochrane Library (from 2000 to March 2019). Clinical studies from controlled trials for shunt operation were included in this analysis. A subgroup analysis was performed based on the patient's age, follow-up time and high-risk population. The fixed effect in RevMan 5.3 software (Cochrane Collaboration) was used for this meta-analysis. Results : This study included 19 controlled clinical trials including 10105 operations. The analysis demonstrated that AISC could reduce the infection rate in shunt surgery compared to standard shunt catheter (non-AISC) from 8.13% to 4.09% (odds ratio [OR], 0.48; 95% confidence interval [CI], 0.40-0.58; p=0.01; I2=46%). Subgroup analysis of different age groups showed that AISC had significant antimicrobial effects in all three groups (adult, infant, and adolescent). Follow-up time analysis showed that AISC was effective in preventing early shunt infections (within 6 months after implant). AISC is more effective in high-risk population (OR, 0.24;95% CI, 0.14-0.40; p=0.60; I2=0%) than in general patient population. Conclusion : The results of meta-analysis indicated that AISC is an effective method for reducing shunt infection. We recommend that AISC should be considered for use in infants and high-risk groups. For adult patients, the choice for AISC could be determined based on the treatment cost.

A Comparative Analysis of Areal Interpolation Methods for Representing Spatial Distribution of Population Subgroups (하위인구집단의 분포 재현을 위한 에어리얼 인터폴레이션의 비교 분석)

  • Cho, Daeheon
    • Spatial Information Research
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    • v.22 no.3
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    • pp.35-46
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    • 2014
  • Population data are usually provided at administrative spatial units in Korea, so areal interpolation is needed for fine-grained analysis. This study aims to compare various methods of areal interpolation for population subgroups rather than the total population. We estimated the number of elderly people and single-person households for small areal units from Dong data by the different interpolation methods using 2010 census data of Seoul, and compared the estimates to actual values. As a result, the performance of areal interpolation methods varied between the total population and subgroup populations as well as between different population subgroups. It turned out that the method using GWR (geographically weighted regression) and building type data outperformed other methods for the total population and households. However, the OLS regression method using building type data performed better for the elderly population, and the OLS regression method based on land use data was the most effective for single-person households. Based on these results, spatial distribution of the single elderly was represented at small areal units, and we believe that this approach can contribute to effective implementation of urban policies.

Using of the "Consolidated Standards of Reporting Trials:CONSORT" to heighten quality of Medical Education study (의학교육연구의 질을 향상시키기 위한 '연구보고의 표준' 의 활용)

  • Yoo, Ji-Soo
    • Korean Medical Education Review
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    • v.10 no.2
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    • pp.25-44
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    • 2008
  • Objectives: Through using of the strong research method like a Randomized Controlled Trial: RCT, we have to heighten quality of Medical Education study. I'd like to introduce "CONSORT", which stands for Consolidated Standards of Reporting Trials. Contents: Preventive Service Task Force(200l) in USA proposed Levels of evidence for enlarging evidence-based Practice: EBP. And the CONSORT was introduced, which encompasses various initiatives developed by the CONSORT Group to alleviate the problems arising from inadequate reporting of randomized controlled trials (RCTs). the CONSORT has 13 guides like these: 1. How participants were allocated to interventions 2. Scientific background and explanation of rationale 3. Eligibility criteria for participants. The settings and locations where the data were collected. 4. Precise details of the interventions intended for each group and how and when they were actually administered 5. Specific objectives and hypotheses 6. Clearly defined primary and secondary outcome measures, When applicable. any methods to enhance the quality of measurements (e.g., multiple observations, training of assessors) 7. How sample size was determined. When applicable, explanation of any interim analyses and stopping rules 8. Method used to generate the random allocation sequence, Details of any restriction [of randomization] 9. Method used to implement the random allocation sequence 10. Who generated the allocation sequence, who enrolled participants. and who assigned participants to their groups 11. Whether or not participants, those administering the interventions, and those assessing the outcomes were blinded to group assignment. If done, how the success of blinding was evaluated 12. Statistical methods used to compare groups for primary outcome(s), Methods for additional analyses, such as subgroup analyses and adjusted analyses 13. Flow of participants through each stage (a diagram is strongly recommended) Specifically, for each group report the numbers of participants randomly assigned. receiving intended treatment, completing the study protocol. and analyzed for the primary outcome. Results and Conclusion: Randomized Controlled Trial: RCT guided of CONSORT will contribute to do stronger evidence-based medical studies.