• Korean Journal of Geomatics
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• 제4권1호
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• pp.17-22
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• 2004

It is very important to manage efficient data for safety and maintenance of those constructs. Estimation for structural safety can be evaluated by using data that surveys various structural durability and safety elements. so, it should be based on synthetic and efficient data that includes a variety of related safety elements obtained from a structure. It will subsequently be managed properly and economically. Accordingly, we will approach efficient maintenance management using a Geographic Information System (GIS) with data from structural-safety diagnosis and a Global Positioning System (GPS). In this study, we noted that by using the data that measures the factors (crack, incline, settlement etc.) of various structures as evaluate safety degree. And the horizontal coordinate variation/time of structure was monitored using the GPS easily.

• Structural Engineering and Mechanics
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• 제30권3호
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• pp.263-278
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• 2008

Structural pipe-in-pipe cross-sections have significant potential for application in offshore oil and gas production systems because of their property that combines insulation performance with structural strength in an integrated way. Such cross-sections comprise inner and outer thin walled pipes with the annulus between them fully filled by a selectable thick filler material to impart an appropriate combination of properties. Structural pipe-in-pipe cross-sections can exhibit several different collapse mechanisms and the basis of the preferential occurrence of one over others is of interest. This paper presents an elastic analyses of a structural pipe-in-pipe cross-section when subjected to external hydrostatic pressure. It formulates and solves the static and elastic buckling problem using the variational principle of minimum potential energy. The paper also investigates a simplified formulation of the problem where the outer pipe and its contact with the filler material is considered as a 'pipe on an elastic foundation'. Results are presented to show the variation of elastic buckling pressure with the relative elastic modulus of the filler and pipe materials, the filler thickness and the thicknesses of the inner and outer pipes. The range of applicability of the simplified 'pipe on an elastic foundation' analysis is also presented. A brief review of the types of materials that could be used as the filler is combined with the results of the analysis to draw conclusions about elastic buckling behaviour of structural pipe-in-pipe cross-sections.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 추계학술대회
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• pp.220-225
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• 2004

The mesh-insensitive structural stress procedure by Dong is modified to apply to the welded joints with local thickness variation and inignorable shear/normal stresses along local discontinuity surface. In order to make use of the structural stress based K solution for fatigue correlation of welded joints, a proper crack growth model needs to be developed. There exist some significant discrepancies in inferring the slope or crack growth exponent in the conventional Paris law regime. Two-stage crack growth model was not considered since its applications are focused upon the fatigue behavior in welded joints in which the load ratio effects are considered negligible. In this paper, a two-stage crack growth law considering high mean loading is proposed and proven to be effective in unifying the so-called anomalous short crack growth data.

• 보건행정학회지
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• 제24권4호
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• pp.380-388
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• 2014

Background: The volume of surgery has been examined as a major source of variation in outcome after surgery. This study investigated the direct effect of surgery volume to in hospitals mortality and the moderating effect of structural complexity-the level of diversity and sophistication of technology a hospital applied in patient care-to the volume outcome relationship. Methods: Discharge summary data of 11,827 cancer patients who underwent surgery and were discharged during a month period in 2010 and 2011 were analyzed. The analytic model included the independent variables such as surgery volume of a hospital, structural complexity measured by the number of diagnosis a hospital examined, and their interaction term. This study used a hierarchical logistic regression model to test for an association between hospital complexity and mortality rates and to test for the moderating effect in the volume outcome relationship. Results: As structural complexity increased the probability of in-hospital mortality after cancer surgery reduced. The interaction term between surgery volume and structural complexity was also statistically significant. The interaction effect was the strongest among the patients group who had surgery in low volume hospitals. Conclusion: The structural complexity and volume of surgery should be considered simultaneously in studying volume outcome relationship and in developing policies that aim to reduce mortality after cancer surgery.

• Structural Engineering and Mechanics
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• 제70권5호
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• pp.525-534
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• 2019

An analytical research on buckling of simply supported thin plate with variable thickness under bi-axial compression is presented in this paper. Combining the perturbation technique, Fourier series expansion and Galerkin methods, the linear governing differential equation of the plate with arbitrary thickness variation under bi-axial compression is solved and the analytical expression of the critical buckling load is obtained. Based on that, numerical analysis is carried out for the plates with different thickness variation forms and aspect ratios under different bi-axial compressions. Four different thickness variation forms including linear, parabolic, stepped and trigonometric have been considered in this paper. The calculated critical buckling loads and buckling modes are presented and compared with the published results in the tables and figures. It shows that the analytical expressions derived by the theoretical method in this paper can be effectively used for buckling analysis of simply supported thin plates with arbitrary thickness variation, especially for the stepped thickness that used in engineering widely.

• 한국구조물진단유지관리공학회 논문집
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• 제14권2호
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• pp.67-74
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• 2010

철근콘크리트 지붕 슬래브에 작용하는 온도변화는 여름에는 부재를 팽창시키고 겨울에는 수축시키기 때문에 콘크리트의 응력변화를 야기시키며 이와 같은 거동은 년단위로 반복되어 사용성과 극한상태 모두에 대해서 부재의 구조성능에 영향을 미친다. 본 논문에서는 최근 20년 동안 한국의 기상변화를 분석하여 온도변화의 패턴을 계산하였으며 또한 이와 같이 장기적으로 반복되는 온도변화에 대한 영향을 실험적으로 연구하였다. 6개의 동일한 형태를 가진 철근콘크리트 슬래브를 제작하고 가력주기와 손상유무를 주 변수로 실험을 실시하였다. 실험으로부터, 1년, 10년 20년 동안의 가력기간 변화에 따른 슬래브의 강성변화에서, 여름의 경우에는 10년에서 1년 일 때의 강성과 비교하여 약 30% 정도 감소되고 겨울의 경우에는 30년 이후부터 약 31%(1년과 비교) 저하되는 것으로 나타났다. 또한 이들 손상된 RC슬래브에 대한 파괴실험을 통하여 슬래브 부재의 보유성능을 평가한 결과, 외기에 노출된 기간의 변화에 따른 슬래브 부재의 초기강성 및 최대내력의 변화는 크지 않은 것으로 나타났다. 단, 20년 이상의 반복온도하중을 받은 경우에는 항복내력이 낮아지는 경향을 보이는 것으로 나타났다.

• Genomics & Informatics
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• 제9권4호
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• pp.152-160
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• 2011

Hypertension is the major factor of most death and high blood pressure (BP) can lead to stroke, myocardial infarction and cardiac failure. Moreover, hypertension is strongly correlated with body mass index (BMI). Although the exact causes of hypertension are still unclear, some of genetic loci were discovered from genome-wide association study (GWAS). Therefore, it is essential to study genetic variation for finding more genetic factor affecting hypertension. The purpose of our study is to conduct a CNV association study for hypertension-related traits, BP and BMI, in Korean individuals. We identified 2,206 CNV regions from 3,274 community-based Korean participants using the Affymetrix Genome-Wide Human SNP Array 6.0 platform and performed a logistic regression analysis of CNVs with two hypertension-related traits, BP and BMI. Moreover, the 4,692 participants in an independent cohort were selected for respective replication analyses. GWAS of CNV identified two loci encompassing previously known hypertension-related genes: LPA (lipoprotein) on 6q26, and JAK2 (Janus kinase 2) on 9p24, with suggestive p-values (0.0334 for LPA and 0.0305 for JAK2 ). These two positive findings, however, were not evaluated in the replication stage. Our result confirmed the conclusion of CNV study from the WTCCC suggesting weak association with common diseases. This is the first study of CNV association study with BP and BMI in Korean population and it provides a state of CNV association study with common human diseases using SNP array.

• Asian-Australasian Journal of Animal Sciences
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• 제32권3호
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• pp.320-333
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• 2019

Objective: The Shanghai Holstein cattle breed is susceptible to severe mastitis and other diseases due to the hot weather and long-term humidity in Shanghai, which is the main distribution centre for providing Holstein semen to various farms throughout China. Our objective was to determine the genetic mechanisms influencing economically important traits, especially diseases that have huge impact on the yield and quality of milk as well as reproduction. Methods: In our study, we detected the structural variations of 1,092 Shanghai Holstein cows by using next-generation sequencing. We used the DELLY software to identify deletions and insertions, cn.MOPS to identify copy-number variants (CNVs). Furthermore, we annotated these structural variations using different bioinformatics tools, such as gene ontology, cattle quantitative trait locus (QTL) database and ingenuity pathway analysis (IPA). Results: The average number of high-quality reads was 3,046,279. After filtering, a total of 16,831 deletions, 12,735 insertions and 490 CNVs were identified. The annotation results showed that these mapped genes were significantly enriched for specific biological functions, such as disease and reproduction. In addition, the enrichment results based on the cattle QTL database showed that the number of variants related to milk and reproduction was higher than the number of variants related to other traits. IPA core analysis found that the structural variations were related to reproduction, lipid metabolism, and inflammation. According to the functional analysis, structural variations were important factors affecting the variation of different traits in Shanghai Holstein cattle. Our results provide meaningful information about structural variations, which may be useful in future assessments of the associations between variations and important phenotypes in Shanghai Holstein cattle. Conclusion: Structural variations identified in this study were extremely different from those of previous studies. Many structural variations were found to be associated with mastitis and reproductive system diseases; these results are in accordance with the characteristics of the environment that Shanghai Holstein cattle experience.

• 한국전산구조공학회논문집
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• 제29권2호
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• pp.115-122
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• 2016

기존 건축물의 구조 안전성평가와 보수 보강 시에는 해당 건축물의 상태를 정확히 알기 위해 현장 또는 실험실에서의 실험을 수행하는 경우가 많고 최초설계 단계와 다르게 시공된 건축물의 실제 상태 등을 구조해석 모델에 반영하게 된다. 이 경우, 각종 실험값을 전통적인 통계학적 방법은 구조기술자가 지닌 경험과 지식은 구조모델링 및 해석에서 아무런 가치를 더 할 수가 없다. 본 논문은 현장 및 실험실에서 얻은 단순한 실험값을 구조기술자의 축적된 경험과 지식을 변수로 활용하여 보다 유효하게 구조해석 모델에 필요한 데이터로 개선하는 방법으로서 통계학적인 베이스 경신법을 이용한 안전성평가 방법에 대해 살펴보았다. 구조기술자의 적절한 판단이 변수로서 포함되면 적은 개수의 샘플 수로도 비교적 정확한 값의 최종 예측값을 산정할 수 있어 전통적인 통계학적 접근에 비해 보다 실제값에 근접한 예측값을 구할 수 있는 것을 확인하였다.

• Structural Engineering and Mechanics
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• 제39권6호
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• pp.849-860
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• 2011

The buckling capacity of the cylindrical shells depends on two geometric ratios of L/R and R/t. However the effect of thickness variation on the behavior of the shells is more complicated and the buckling strength of them is sensitive to the magnitude and shape of geometric imperfections. In this paper the effects of thickness variation and geometric imperfections on the buckling and postbuckling behavior of cylindrical shells are experimentally investigated. The obtained results are presented under the effect of uniform lateral pressure. It is found in this investigation that the buckling mode can be generated in the whole length of the shell, if the thickness variation is low.