• Maxillofacial Plastic and Reconstructive Surgery
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• v.30 no.2
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• pp.205-212
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• 2008

Genetic variation in the human genome occurs on various levels; from the single nucleotide polymorphism to large, microscopically visible chromosome anomalies. It can be present in many forms, including variable number of tandem repeat (VNTRs; e.g., mini- and microsatellites), presence/absence of transposable elements (e.g., Alu elements), single nucleotide polymorphisms, and structural alterations (e.g., copy number variation, segmental duplication, inversion, translocation). Until recently SNPs were thought to be the main source of genetic and phenotypic human variation. However, the use of methods such as array comparative genomic hybridization (array CGH) and fluorescence in situ hybridization (FISH) have revealed the presence of copy number variations(CNVs) ranging from kilobases (kb) to megabases (Mb) in the human genome. There is great interest in the possibility that CNVs playa role in the etiology of common disease such as HIV-1/AIDS, diabetes, autoimmune disease, heart disease and cancer. The discovery of widespread copy number variation in human provides insights into genetic variability among populations and provides a foundation for studies of the contribution of CNVs to evolution and disease.

• Economic and Environmental Geology
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• v.35 no.5
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• pp.455-463
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• 2002

There have been few geophysical studies on the crustal structure of the continent-ocean zone around the middle eastern part of Korean peninsula, because of the lack of database in both land and ocean. The area for the study on the internal crustal structure using gravity data is bounded by the latitude of 37$^{\circ}$-38"N and longitude of 128$^{\circ}$-132$^{\circ}$E. WCA correction is applied to shipborne gravity data to integrate with gravity anomalies obtained on land. The high frequency components of the shipborne gravity data which are considered as the noise on survey track are effectively removed by means of correlating with satellite gravity data. The corrected shipborne free-air gravity anomaly is integrated with the Bouguer gravity anomaly on land under the same condition. The integrated gravity anomaly is divided into four areas for power spectrum analysis. The depths of Moho discontinuity increases gradually from inland to Ulleung basin. As the result of modeling based on power spectrum analysis, Moho discontinuity depth is about 33-35 km in the continental zone of Korea and 18-28 km at the continental margin. Such structural character is well elucidated in changing gravity data around Ulleung basin. The depths of Moho discontinuity in the southern ocean of Ulleung-island is 16--17 km, which is much lower than in the land. The result of crustal structure modeling in this study is similar to that computed by prior seismic exploration around this area.

• Geophysics and Geophysical Exploration
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• v.16 no.1
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• pp.36-44
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• 2013

We conducted the airborne magnetic and radiometric survey for the characterization of the black shale related and pyrometamorphic uranium deposits distributed in Geumsan area. For the successful characterization of the uranium deposits, the general geological and structural geological features were investigated based on the lithological and linear feature analysis to individual magnetic and radiometric data as the first step. Lithological analysis from the magnetic reduction to the pole and downward continuation map revealed that prominent positive anomalies caused by black and dark gray slate member were clearly recognized as magnetic sources. These results indicate that magnetic survey, even though it is not a direct method for the detection of uranium, can be a useful tool in uranium detection. By the linear feature analysis based on 2nd vertical derivative and curvature map, two linearments corresponded the gray hornfels and black slate member were extracted and in succession, the additional uranium potential zone was inferred. Final discrimination whether uranium-rich or not was confirmed by radiometric and uranium anomaly map. From these analysis, we finally concluded that uranium deposit originated by pyrometamorphic process was confined near the intrusive area only. On the contrary, it was found that black shale related uranium deposit is distributed and extended through out the entire survey area with south-west to north-east direction. In addition, from the linear feature analysis based on radiometric total anomaly map, the typical discontinuous characteristics were recognized in areas where uranium-contained linearments cross the faults. From the above discussion, we concluded that airborne magnetic and radiometric survey are complementary to each other. So it is preferable to carry out simultaneously for the efficient data processing and fruitful interpretation.

• Korean Journal of Optics and Photonics
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• v.22 no.4
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• pp.184-190
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• 2011

A compact imaging spectrometer (COMIS) was developed for a microsatellite STSAT-3. The satellite is now rescheduled to be launched into a low sun-synchronous Earth orbit (~700 km) by the end of 2012. Its main operational goal is the imaging of the Earth's surface and atmosphere with ground sampling distance of 27 m and 2 - 15 nm spectral resolution over visible and near infrared spectrum (0.4 - 1.05 ${\mu}m$). A flight model of COMIS was developed following an engineering model that had successfully demonstrated hyperspectral imaging capability and structural rigidity. In this paper we report the environmental test results of the flight model. The mechanical stiffness of the model was confirmed by a small shift of the natural frequency i.e., < 1% over 10 gRMS random vibration test. Electrical functions of the model were also tested without showing any anomalies during and after vacuum thermal cycling test with < $10^{-5}$ torr and $-30^{\circ}C\;-\;35^{\circ}C$. The imaging capability of the model, represented by a modulation transfer function (MTF) value at the Nyquist frequency, was also kept unvaried after all those environmental tests.

• Korean Journal of Materials Research
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• v.27 no.12
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• pp.705-709
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• 2017

The electronic and optical characteristics of molybdenum disulphide ($MoS_2$) film significantly vary with its thickness, and thus a rapid and accurate estimation of the number of $MoS_2$ layers is critical in practical applications as well as in basic researches. Various existing methods are currently available for the thickness measurement, but each has drawbacks. Transmission electron microscopy allows actual counting of the $MoS_2$ layers, but is very complicated and requires destructive processing of the sample to the point where it will no longer be useable after characterization. Atomic force microscopy, particularly when operated in the tapping mode, is likewise time-consuming and suffers from certain anomalies caused by an improperly chosen set point, that is, free amplitude in air for the cantilever. Raman spectroscopy is a quick characterization method for identifying one to a few layers, but the laser irradiation causes structural degradation of the $MoS_2$. Optical microscopy works only when $MoS_2$ is on a silicon substrate covered with $SiO_2$ of 100~300 nm thickness. The last two optical methods are commonly limited in resolution to the micrometer range due to the diffraction limits of light. We report here a method of measuring the distribution of the number of $MoS_2$ layers using a low voltage field emission electron microscope with acceleration voltages no greater than 1 kV. We found a linear relationship between the FESEM contrast and the number of $MoS_2$ layers. This method can be used to characterize $MoS_2$ samples at nanometer-level spatial resolution, which is below the limits of other methods.

• The Journal of the Petrological Society of Korea
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• v.14 no.2 s.40
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• pp.116-126
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• 2005

The Precambrian quartzite and calc-schist layers experienced multi-1310ing events are distributed along the two kinds of U-shaped 1310 (Fold I and II) with $N10^{\circ}E-directed$ fo1d axis in Wollong-myeon, Gwangtan-myeon, Jori-myeon of Paju city, the northeastern part of Gyeonggido. Occurrence of 10 layers of quartzite and 4 layers of calc-schist is not clear whether quartzite and schist layers were deposited sequentially each other or one to two layers of quartzite and schist were distributed repeatedly by isoclinal folding and thrusting, because of lack of sedimentary structures. In this paper, we tried to clarify the correlative relationship among the quartzite beds which are distributed along the U-shaped folds using geochemical tools such as rare earth element (REE) patterns and Nd isotope ratio. Quartzites have characteristics of LREE-flattened, HREE- slightly depleted patterns. They also show Ce negative anomaly whereas there are no Eu anomalies. As a result, quartzite beds occurred along the bilateral sides of fold axis show very similar REE patterns from outer side to inner side of 1314. The Nd model age of quartzite layers shows a trend that the inner part of fold is younger than the outer part of it. Such geochemical characteristics suggest that bilateral quartzite beds occurred along the fold axis were derived from the cogenetic source materials. The REE patterns and trace element geochemistry of mica schist intercalated within quartzite indicate that the quartzite and mica schist may be derived from different source materials. Our results suggest that REE and Nd isotope geochemistries may be very useful in clarifying the relationship of sedimentary deposits which do not show stratigraphical and structural connections in the field.