• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.232.2-232.2
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• 2003

Many neurodegenerative disorders such as stroke, Alzheimer's disease, and Parkinson's disease have been known to be associated with an excessive generation of reactive oxygen species (ROS) and oxidative stress. Therefore, the antioxidants have recently received much attention as therapeutic agent for the treatment of neurodegenerative disease. (omitted)

• 한국해양공학회지
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• 제33권6호
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• pp.504-509
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• 2019

The wave-generation performance of a piston-type wave maker was analyzed using the numerical wave tank technique, and the numerical results were compared with theoretical solutions. A two-dimensional frequency domain analysis was conducted based on the Rankine panel method. Various parameters were used to examine the wave-generation performance, such as the width and gap of the wave board. The effects of the thickness of the wave board and of the gap from the bottom of the tank were evaluated. The difference in the amplitude of the generated wave between the analytical solution and the numerical result was examined, and its causes were addressed due to the gap flow between the bottom of the tank and the wave board. This parametric analysis can be utilized to design an optimum wave make parametric analysis to design an optimum wave maker that can generate waves with amplitudes that can be predicted accurately.

• 대한기계학회논문집A
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• 제28권12호
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• pp.1937-1941
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• 2004

We present lateral actuated piezoelectric actuator using U-shaped PZT strip and lever structure for the RF switch application. In the previous study of RF switch, they used horizontal contact switch fabricated by thin film metals. However, thin film metals could not generate large contact force due to low stiffness. In this work, we suggest lateral contact switch which makes large contact force by increasing stiffness. In addition, we use PZT actuator for the high force actuation. Generally actuator using thin film PZT moves to the vertical direction due to the neutral axis shift. Therefore we need lateral motion generation mechanism based on the thin film PZT actuator. In order to increase lateral motion of thin film PZT actuator, we use U-shaped PZT actuator using residual stress control. Also, thin film PZT actuator can generate very small lateral motion of 120${\times}$10$^{-6}$ ${\mu}{\textrm}{m}$/V for d$_{31}$ mode, thus we suggest lever structure to increase stroke amplification. From the experimental study, fabricated PZT actuator shows maximum lateral displacement of 1 ${\mu}{\textrm}{m}$, and break down voltage of the thin film PZT actuator is above 16V.

• 소음진동
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• 제8권2호
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• pp.239-250
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• 1998

Traditionally, intake noise from internal combustion engine has not recevied much attention compared to exhaust noise. But nowadays, intake noise is a major contributing factor to automotive passenger compartment noise levels. The main objective of this paper is to identify the mechanism of generation, propagation and radiation of the intake noise. With a simplest geometric model, one of the main noise sources for the intake stroke is found to be the pressure surge, which is generated after intake valve closing. The pressure surge, which has the nonlinear acoustic behavior, propagates and radiates with relatively large amplitude. In this paper, unsteady compressible Navier-Stokes equations are employed for the intake stroke of axisymmetric model having a single moving cylinder and a single moving intake valve. To simulate the periodic motion of the piston and the valve, unsteady deforming mesh algorithm is employed and Thompson's non-reflecting boundary condition is applied to the radiation field. In order to resolve the small amplitude waves at the radiation field, essentially non-oscillatory(ENO) schemes with an artificial compression method (ACM) are used.

• 한국소음진동공학회논문집
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• 제27권1호
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• pp.14-19
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• 2017

Fuel oil consumption cost varies depending on every ship operation and this roughly amounts to 70 % of shipping companies' total revenue. As such, efforts towards improved fuel economy are being pursued. An annual 1 % reduction in fuel consumption is perceived to result in saving tens million US dollars on the global fleet operation. One approach is the application of power take-off configurations which are seen to increase fuel oil economy and are suitable for power generation. In this study, the dynamic properties of a shaft generator coupled on a 10S90ME main engine of an 18 600 TEU container vessel is presented. The vibratory torque and angular velocity variation was examined through theoretical analysis and actual vibration measurement. The result of the study suggests a review on existing classification rules for generator design and the lowering of vibratory torque and angular velocity variation guideline.

• 대한한방내과학회지
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• 제20권1호
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• pp.210-221
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• 1999

A clinial observation was done on 12 cases of paralytic ileus patients, treated by Bo-Ryu Enema(保留灌腸), who were hospitalized from May 1, 1995 to October 31, 1996 at the Department of Oriented Internal Medicine II, Oriental Medicine Hospital. Taejon University. The results were as follows; 1. The ratio between male and female was 1 : 1.4. The distribution of age. 70' years or over, 60', 50' years generation were revealed in turn. 2. In classiffication of human coporeal constitution, Soeumin(少陰人) were 9 cases(75.0%), Taeumin(太陰人) 2 cases (16.7%), Soyangin(少陽人) 1 case (8.3%). 3. In distribution of disease on admission, Stroke sequela was the most number with 7 cases(58.3%), Stroke 3 cases(25.3%). Hypertensive encephalopathy and Brain tumor were 1 case, each other. 4. The effect of treated by Bo-Ryu Enema was as follows: Each of Excellent(良好) and Good(好戰) were 6 cases(50%) but. Fair(別無好戰) and Poor(惡化) were no case.

• Annals of Clinical Neurophysiology
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• 제8권1호
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• pp.53-57
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• 2006

Background: Vstibular evoked myogenic potentials(VEMP) have been known to be useful documenting abnormality in patients with various vestibular disorders and brainstem lesions but the studies of VEMP in patients with hemispheric lesions are rare. Methods: We recorded VEMP in 21 consecutive patients with acute ischemic stroke in the supratentorial lesions without evidence of brainstem or vestibular end organ lesions. All patients underwent magnetic resonance imaging and the main outcome measures of VEMP were recorded in all subjects. We interpreted each parameters of VEMP using our normal laboratory data. Results: VEMP abnormalities(prolonged latency or asymmetry of amplitude) were found in 57%(12/21) of acute infarction patients with supratentorial lesions. Bilateral VEMP abnormalities were found in six patients and unilateral abnormalities were found in another six patients with ipsilateral abnormalities in the three and controlateral abnormalities in the three patients. Conclusions: VEMP abnormalities were found in supratentorial stroke patients in our studies and this findings suggest supranuclear control may affect the generation of VEMP potentials.

• 한국컴퓨터그래픽스학회논문지
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• 제9권1호
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• pp.11-18
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• 2003

본 논문에서는 회화적 렌더링에서 칼라변환을 이용한 브러쉬 스트로크의 생성에 관한 새로운 알고리즘을 제안한다. 본 논문의 브러쉬 스트로크 생성을 위한 전체적인 구성은 다음과 같다. 첫째, 두 장의 사진(한 장의 소스 이미지와 한 장의 참조 이미지)을 입력으로 하여 칼라 변환 이론을 적용하여 색상 테이블이 바뀐 새로운 이미지를 생성한다. 이 방법은 소스 이미지의 칼라 분포 형태를 창조 이미지의 칼라 분포 형태로 변환하기 위해, 선형 히스토그램 매칭이라 불리는, 간단한 통계학적 방법을 이용한다. 둘째, 가우시안 블러링과 소벨 필터를 이용하여 에지를 검출한다. 검출된 에지는 브러쉬 스트로크 렌더링 시 에지 부분에서 스트로크를 클리핑 함으로써 이미지의 윤곽선 보존을 위해 사용된다. 셋째, 브러쉬 스트로크의 방향을 결정하기 위한 방향맵을 생성한다. 방향맵은 입력 영상에 대한 영역 분할 및 병합을 토대로 만들어진다. 영역별 각 픽셀들에 대해 이미지 그래디언트에 기초한 일정한 방향을 부여함으로써 방향맵을 구성한다. 넷째, 구성된 방향맵을 참조하여 브러쉬 스트로크 생성의 기초가 되는 베지어 곡선(Bezier Curve)의 제어점(Control point)을 설정한다. 실제 회화작품에서 사용되는 브러쉬 스트로크는 일반적으로 곡선의 형태를 이루므로 곡선 표현이 가능한 베지어 곡선을 이용하여 브러쉬 스트로크를 표현하였다. 마지막으로, 생성된 브러쉬 스트로크를 에지부문에서 클리핑하고 배경색을 참조하여 블렌딩하거나 퐁 조명 모델을 이용하여 이미지에 적용하게 된다.

• 생명과학회지
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• 제18권3호
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• pp.311-317
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• 2008

Pathophysiological oxidative stress results in neuronal cell death mainly due to the generation reactive oxygen species (ROS). In low oxygen situation such as hypoxia and ischemia, excessive ROS is generated. Coptidis Rhizoma (CR) is a traditional medicine used for the incipient stroke. In this report we show that CR water extracts $(1\;{\mu}g/ml)$ exhibited protective effects of neuronal cell death in a hypoxic model (2% $O_2/5%\;CO_2,\;37^{\circ}C,$ 3 hr) of cultured rat cortical cells. We further show that CR water extracts significantly reduced the intensity of green fluorescence after staining with $H_2DCF-DA$ on one hour and three days after hypoxic shock and in normoxia as well. Our results indicate that CR water extracts prevent neuronal death by suppressing ROS generation.

• 한국분말야금학회:학술대회논문집
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• 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part2
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• pp.1276-1277
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• 2006

The ever increasing requirements on today's compacts with regard to their geometry and precision call for flexible high-precision and most capable production systems. DORST Technologies has coped with these requirements by developing the new HP series for pressing forces between 1600 kN and 16000 kN and the new HS series for pressing forces between 150 kN and 1200 kN. These fully hydraulic presses featuring upper ram, lower ram, core rod, filler, up to 4 lower tool levels and up to 4 upper tool levels with closed-loop controlled movements. Thanks to latest servo technology and an electronic bus system it is possible to have all movements closed-loop controlled in the desired relation to each other. Thus, today's hydraulic presses provide high stroke rates, low energy consumption and a user-friendly interface. The input of data is carried out via clearly arranged screen masks on a touch-screen. The innovative DORST $IPG^{(R)}$ (Intelligent Program Generator) has been designed to support the set-up staff in preparing and optimizing the toolprogram. The combination of the machine type with the hydraulic unit determines the productivity in consideration of the specific application and the part to be pressed. Thanks to the closed-loop control circuits, DORST hydraulic automatic presses of the latest generation ensure unmatched precision and repeatability - and consequently process reliability - often without necessitating subsequent machining steps.