• BMB Reports
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• v.49 no.11
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• pp.635-640
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• 2016

Recent evidence indicates that the ephrin receptors and ephrin ligands (Eph/ephrin) expression modulate axonal reorganization and synaptic plasticity in stroke recovery. To investigate the effect of task-specific training (TST) on Eph/ephrin expression in the corticospinal tract (CST) after stroke, we compared Eph/ephrin expression in the peri-infarct cortex, pyramid, and spinal cord of a photothrombotic stroke model of rat brains treated with or without TST. The TST treatment showed significantly better recovery in the behavioral tests compared with no treatment. The significant upregulation of ephrin-A1 and ephrin-A5 observed in activated astrocytes of the CST at 2 weeks' post-stroke was decreased by TST. At 5 weeks, post-stroke, the elevated ephrin-A5 levels were decreased in the ipsilateral pyramid and spinal cord by TST. Glial fibrillary acidic protein was upregulated concomitantly with the altered ephrin expression after stroke, and the expression of these proteins was attenuated by TST. These data suggest that TST alters the expression of ephrin ligands in the CST after stroke.

• The Journal of Korean Physical Therapy
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• v.23 no.3
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• pp.43-47
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• 2011

Purpose: This study determined the best adjustable height supporter for stroke patients in wheelchairs for the maintenance of a symmetric sitting posture. Methods: Thirty-one stroke participants and 20 age-matched control participants were recruited. The enrolled participants were evaluated by the Force Sensitive Application (FSA) System that was used to assess weight shift and symmetry in wheelchair sitting and assess the symmetric index (SI) of subjects according to 1, 2 and 3 cm height supporters. Results: When a 1 cm height supporter was applied to the paretic side of stroke survivors, sitting postures of stroke patients were significantly more symmetrical (p<0.01). Cross tabulation between the SI of wheelchair sitting and that of the paretic side of stroke patients caused? by a 1 cm supporter showed that 21 SIs of 26 stroke patients were improved by a 1 cm supporter to the paretic side (k=0.26, p<0.01). Conclusion: The findings of the present study demonstrate that stroke patients can maintain a more symmetrical sitting posture (than is possible when simply sitting in a wheelchair seat) if a 1 cm supporter is applied to the paretic side of stroke patients.

• The Journal of Korean Physical Therapy
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• v.27 no.5
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• pp.375-380
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• 2015

Purpose: The purpose of this study was to evaluate the impact of differences in computer-aided cognitive rehabilitation aimed at stroke patients on cognitive function and daily life. Methods: The study subjects were Gwangju, Jeonnam including the attention group (group I), memory group (group II), and visual perception group (group III), who were randomly placed in each of a 10 by one problem solving group (group IV). The PSSCogRehab was applied to all subjects who underwent eight weeks once a week after 20 minutes in each group by strengthening mediation 10 minutes 30 minutes total, with a five minute break in the middle. Results: Cognitive function and activities of daily living is security and inter-group differences before intervention, and post-test results in the memory training group II, the intervention group I, III, IV and more on cognitive function and activities of daily living compared to it was effective. Conclusion: The results of computer-aided cognitive rehabilitation measuring cognitive function and ADL in patients with stroke in accordance with the group I, III, and IV group cognitive function and activities of daily living compared to IV showed that it was more effective.

• Research in Community and Public Health Nursing
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• v.17 no.2
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• pp.166-175
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• 2006

Purpose: This study was to evaluate the effects of a rehabilitation exercise program on physical function and mental health status in chronic stroke Patients with hemiparesis Method: This study used a single group experimental design with repeated measures. Data collection and intervention were done from August, 2004 to November. 2004 at a community. Participants were fifteen patients (mean age: 68.6), and a 100 meter walking time and box and block tests were conducted at baseline, 4weeks, and post-intervention (8weeks) Activities of daily living and the levels of depression and anxiety were measured by using SCL-90-R at pre and post Intervention. This program consisted of 1 hour individual exercise 3 times a week for 8 weeks, and it focused on stretching, walking, arm and hand exercise, and hand massage. Result: 1. ADL, IADL, and the 100m walking time in the patients were improved compared with baseline. However. box and block tests was not shown significant improvement compared with baseline. 2. Depression and anxiety scores were improved more than that of baseline. Conclusion: The rehabilitation exercise program can be effective in improving physical function and mental health status, and it has a potential for improving Physical health status in Patients with chronic stroke hemiparesis.

• Journal of the Korean Society of Physical Medicine
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• v.14 no.1
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• pp.7-14
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• 2019

PURPOSE: This study examined the effects of observing a self-video or a video of another person performing balance and gait training, followed by actual performance of the observed movements on the balance and walking ability of chronic stroke patients. METHODS: Thirty patients, who had experienced a stroke and were admitted to S rehabilitation hospital for treatment, were selected randomly and divided into three groups with 10 patients each: self-action observation (SAO) group, other-action observation (OAO) group, and treadmill walking training (TWT) group. The training program was conducted five times per week for four weeks. The GAITRite system, 10 m walking test, and timed up and go test were performed to measure the subjects' gait and balance ability. RESULTS: The velocity, cadence, double support, and stride length were increased significantly in the SAO and OAO groups (p<.05) but the T group showed no significant changes; no significant difference was observed among the groups (p >.05). The 10MWT decreased significantly in the OAO group (p<.05), but there were no significant changes in the SAO and T groups, and no significant difference was observed among the groups (p>.05). The TUG decreased significantly in the SAO and OAO groups (p<.05), but there were no significant changes in the T group, and no significant difference was observed among the groups (p>.05). CONCLUSION: The self or other action observation training helps improve the balance and gait ability.

• The Journal of Internal Korean Medicine
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• v.38 no.2
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• pp.118-124
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• 2017

Objective: This study describes the case of a patient with a left basal ganglia (BG) infarct who had made almost a complete recovery upon discharge from the hospital in 2014 but who was re-admitted after 31 months with a worsened hemiplegic gait. Methods: The patient had undergone no rehabilitation treatment in the 31 months since his discharge. When the patient was re-admitted to our hospital in 2017, stance and gait data were collected on the patient using a treadmill gait analysis system. In addition, the patient underwent a manual muscle test (MMT) evaluation, and his Motricity index (MI) and modified Barthel index (MBI) scores were recorded. After rehabilitation for one month, the patient was reassessed, and the results were compared to those on the day of re-admission and those recorded in 2014. Results: Compared to the 2014 evaluation results, the patient's stance parameters and gait parameters had worsened at re-admission. However, there was no significant change in the patient's MMT grade or MI and MBI scores in comparison to the results of the 2014 evaluation. After one month of rehabilitation, the patient was re-evaluated again, but there was no significant change in comparison to the evaluation results at re-admission. Conclusion: Some of the stroke patients who have passed six months since the onset of their stroke may require ongoing rehabilitation although the functions of them is almost recovered. Because there is a possibility that recovered functions get worse again without any rehabilitation for a long time. And once the recovered functions get worse, re-recovery of them is not easy.

• Journal of the Korean Society of Physical Medicine
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• v.15 no.4
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• pp.145-153
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• 2020

PURPOSE: This study compares the effects of HUBER rehabilitation and general rehabilitation treatment on the coordination, balance, and walking ability of stroke patients. METHODS: This study enrolled 38 randomized stroke patients, and data was collected for 6 weeks. All participants were randomly assigned to either the experimental group (n = 19) or control group (n = 19). The experimental group were administered Huber rehabilitation and general rehabilitation treatment. The control group was given only general rehabilitation treatment. Both treatments were conducted for 30 minutes during each training session, 3 training sessions per week, for 6 weeks. The coordination, balance, and walking ability were evaluated before and after the intervention, to compare the intergroup and intragroup changes. RESULTS: Change in the right LOS (limit of stability) (p < .001) and forward LOS (p < .02) following intervention were significantly greater in the experimental group than in the control group, but no significant group difference was observed between left LOS (p > .1) and backward LOS (p > .2). Alterations in coordination (p < .02) and TUG (p <. 05) were significantly greater after intervention in the experimental group than in the control group. CONCLUSION: These findings suggest that HUBER rehabilitation is effective in improving the coordination, balance, and walking ability in stroke patients. To strengthen and validate the results of this study, future studies related to HUBER rehabilitation are required.

• Journal of Society of Preventive Korean Medicine
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• v.15 no.1
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• pp.131-143
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• 2011

Objective : The purpose of this study was survey about the recognition and demand on cooperative system between western and oriental medicine of stroke patients in National Rehabilitation Center. Methods : The participants were 205 stroke patients in the National Rehabilitation Center and investigated the recognition and demand on cooperative system between western and oriental medicine. Results : As to general characteristics of the group, 56.9% were male, 30.7% were in the 60~69 age, 24.3% of patients had an average income per month 1.0~2.0 million. In regard to disease status of patients, 53.8% were cerebral infarction, 35.8% were below 6 month in disease duration, 73.7% were none recurrence, 52.8% were hypertension as related disease, 74.5% were motor paralysis sequela. 83.2% were positive response in using oriental medicine department of National Rehabilitation Center. The most wanted therapy was acupuncture. Most of respondents expected that co-operative treatments were to be improving the cure effect for patients. And they wanted cooperative system combined evenly between western and oriental medicine, so the western doctors and the oriental doctors suggest the plan giving lots of medial benefits for patients. Conclusion : This survey showed the recognition and demand on cooperative system between western and oriental medicine of patients in National Rehabilitation Center. It is possible to realize patient's centered treatment under the stable and efficient cooperation of western and oriental medicine.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2011.06a
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• pp.345-346
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• 2011

• The Journal of Korean Physical Therapy
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• v.27 no.5
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• pp.311-314
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• 2015

Purpose: This study attempted to determine intra-rater reliability and inter-rater reliability for measurement of foot form using the FPI-6 (Foot Posture Index) in patients with hemiplegia caused by stroke. Methods: Twenty two stroke patients were recruited into the research and their foot posture was evaluated using the FPI. Two raters assessed 6 items sequentially in accordance with the FPI-6 manual. This procedure involved asking the subject to take several steps in-place, prior to settling into a comfortable stance position with double limb support. Subjects were instructed to stand still with their arms by their sides and look straight ahead. FPI-6 values ranged from -2 to +2 for each of the six criteria and from -12 to +12 for the total score, indicating a position for each foot either along the supinated (negative score) to pronated (more than +6) continuum of foot posture. Results: The results showed that intra-rater reliability and inter-rater reliability for a total FPI-6 score was high: 0.807-0.888. An almost perfect agreement between the two raters was identified in the foot's morphological classification (Somer's D=0.712; p<0.05). Intra-percentage agreement was high (88.6%). Conclusion: The FPI-6 is a quick, simple, and reliable clinical tool with demonstrated good to excellent intra-rater reliability and good inter-rater reliability when used in assessment of the stroke patient's foot.