• 제목/요약/키워드: Stressor

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스트레스와 면역계 (Stress and the lmmuns System)

  • 백영한
    • 월간산업보건
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    • 통권89호
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    • pp.39-41
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    • 1995
  • 스트레스의 정의 스트레스란 엄밀히 말해서 하나의 힘(force)이며 이 힘이 한 체계(System)에 가해졌을때는 그 양태(form)를 변경시킨다. 사건(events)이나 상황의 형태로서의 심리적 및 사회적인 힘(force)이나 압력(pressure)이 한 개인의 평형을 왜곡시킬 결과를 초래할때 그것들을 스트레스라고 할 수 있다. 심리적긴장도 또한 스트레스라고 할 수 있는데 이 경우에 긴장을 야기시키는 인자를 "스트레써(stressor)"라고 할 수 있다. 스트레스는 반드시 나쁜 것이라고는 말할 수 없다. 왜냐하면 적은 양의 스트레스는 우리들에게 동기유발을 주기때문이다(환언하면 무스트레스도 스트레스다). 예를 들어 한 위기상황은 우세를 되찾기 위한 전향적 사고를 불러일으킴으로써 사태를 극복케하여 성공에 이르도록 하는 사례가 종종 있다.

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스트레스에 의한 혈당변화가 타액선내 Clusterin 발현에 미치는 영향 (Clusterin(SGP-2) in the Salivary Glands of Insulin Injected Rats under Stress)

  • 김선호
    • Journal of Oral Medicine and Pain
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    • 제23권4호
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    • pp.309-326
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    • 1998
  • In general, the major causative factor of halitosis is thought to be a sulfated compounds. Clusterin, a sulfated glycoprotein-2(SGP-2), is frequently found in diabetic conditions and cold stress conditions. The same result is werum glucose level to diabeteic and cold stress conditions that founded Clusterin. Therefore, this study was performed to examine Clusterin in the slivary glands under stress conditions before insulin injection I.M. Fourty rats were diveded into 3 groups ; 1) 10 rats of gorup I were selected as a control 2) 15 rats beloning to group II were bathed in cold water for 30 seconds twice a day 3) 15 rats in group III received cold stress and injected I.M. with insulin. The rats were sacrifeced at day 0, 3, 5, 7 and 10 of the experiment and the submandibular glands and parotid galnds were removed. RNAs were purified from the salivary of the salivary glands were subjected to Hematoxillin-Eosin stainings and examined under the light microscope. The obtained results were as follows : 1. With immunohistochemistric method, in normal control goup, Clusterin was moderately stained in the intercalated ductal cell of the submandibualr glands, mild stained in the striated ductal cell of the submandibular glands, heavily stained on the cytoplasm of the intercalated ductal cell in the mucous submandibular glands nad slightrly stained in the intercalated ductal cell of the paroted gland, expressed negativity in the acina cell. 2. With immunohistochemistric method, Clusterin slightly increased in the acina cell of the submandibular glands under stress condition at 3 days after experement, moderately stained at 5 days after experiment so revealed positive response. And hearily in the intercalated ductal cell and mildly lin the acina celluar eytoplasm of the parotid glands under stress condition at 3 days experiment. 3. With immunohistochemistric method, no remarkable differences are found between the normal control group and stress conditioned group that insulin administration was performed before. 4. In the stressor-giving group, Clusterin mRNA was porminently expressed in submandibular gland after 5 days after experiment, in parotid gland after 3 days after experiment, performed in immunoelectrophoresis method. 5. In the insulin-injected nad stressor-giving group, Clusterin mRNA was not observed in all experimental submandibular and parotid gland, performed in immunoelectrophoresis method.

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백두산 자생참돌꽃의 생육과 이용 II. 유식물의 부위별 superoxide dismutase 활성 (Growth and Utility of Rhodiola sachalinensis in Baekdu Mountain II. Activities of Superoxide Dismutase in Portions of the Seedlings)

  • 소상섭
    • 환경생물
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    • 제26권4호
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    • pp.349-354
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    • 2008
  • 참돌꽃 유식물에서 줄기와 뿌리의 부위별로 나타나는 superoxide dismutase(SOD)의 활성과 환경 스트레스 또는 항산화분자 처리에 따른 SOD활성도를 조사하여 다음과 같은 결론을 얻었다. SOD의 활성은 줄기보다는 뿌리에서 높았고 각 기부보다는 선단부에 이를수록 높았으며 이러한 현상은 유식물 생육의 초기보다 후기에 더 상승된 결과를 나타내고 있다. 또한 환경 스트레스에 대한 SOD의 활성도는 유식을 초기생육 상태에서는 NaCl또는 cadmium(Cd) 등 유해물질 처리 후 10 및 30% 정도 저해를 받고 있으나 생육 후기에 이를수록 처리된 유해인자에 의한 산화적 스트레스에 대하여 유식물은 자체의 SOD 활성 수준이 상향되는 방어능력을 보였으며 이러한 현상은 뿌리에서 더욱 현저하였다. SOD 활성도를 높이기 위해 항산화물질로 ascorbic acid를 처리한 유식물은 생육 후 최고 46%까지 높아짐을 보였으나 동시기의 스트레스 물질로 첨가한 cadmium 처리구에서 나타난 SOD 활성도에 비하여 유의할만한 상승효과의 차이를 보이지는 않았다. 이러한 결과는 참돌꽃 유식물 특히 뿌리부위는 항산화 기질의 처리 없이도 유해한 환경 인자에 노출되면 자체의 방어 수단으로 SOD 생성이 활발히 진행되고 있음을 시사하였다.

소음(騷音) Stress에 의한 요(尿)중 Catecholamine의 분비량(分泌量) 변화(變化) (A Study on the Change of Urinary Catecholamine Sexcretion due to Noise Stress)

  • 김형석;전준배
    • Journal of Preventive Medicine and Public Health
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    • 제26권4호
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    • pp.565-573
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    • 1993
  • Noise is not only affecting the ear and the auditory cortex locally, but its influence is widely spread throughout the brain structures, e. g., the reticular formation, the brain stem nuclei or the subcortical forebrain area. Hence, any of the organism's activities can be hindered or stimulated by noise. High noise is a stressor and the catecholamine level can be used both as a stress marker and as an indicator of modified sympathetic nervous system activity. Several recent studies have found that the urinary excretion of catecholamines is increased due to high noise intensity, especially unexpectedly high and long lasting noise. The present study was conducted in order to examine the effects of noise stress on urinary excretion of ctecholamines in rats and humans. Rats were exposed to 90 dB noise for 10, 30, and 60 minutes, 3 and 12 hours. 24 hour . urinary samples were collected and the catecholamones were extracted by alumina and analyzed by HPLC-ECD. Catecholamine levels increased with time of exposure up to 60 minutes : norepinephrine concentration at 60 min of noise=1.038 ng/ml, epinephrine=0.636 ng/ml. Urine catecholamines of blue collar workers exposed to 90 dB of noise at the work place were collected between 2 and 4 p.m. and compared to that of white collar workers exposed to 70 dB. Mean norepinephrine level of the blue collar workers was 0.89 ng/ml (${\pm}0.25$), epinephrine 0.24ng/m1 (${\pm}0.09$), and that of the white collar workers 0.48 ng/ml (${\pm}0.12$), epinephrine 0.19 ng/ml(${\pm}0.05$). It was concluded that noise acts as a stressor and increases the catecholamine levels in both rats and humans.

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Preliminary Studies on Mercury Bioaccumulation within Various Fish Tissues as Heavy Metal Stressor in Aquatic Ecosystems

  • Lee, Eui-Haeng;An, Kwang-Guk
    • 생태와환경
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    • 제40권4호
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    • pp.569-575
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    • 2007
  • This study was carried out to determine bioaccumulation levels of total mercury on various fish tissues in two streams (Banseok and Hasin Stream) and one lake (Yeongsan Lake) during April-May 2007. We also determined natural background levels of total mercury bioaccumulation to evaluate relative individual impacts of fish and compared the levels with reference sites as a preliminary study to evaluate heavy metal stressor using fish. For the study, we collected fishes in the sampling sites and analyzed the concentrations of total mercury in the liver, kidney, gill, vertebral column, and muscle tissues using Direct Mercury Analyzer (DMA-80, US EPA Method 7473). The levels varied depending on the types of waterbody and tissues used. Concentrations of total mercury ranged between 5.1${\mu}g$ $kg^{-1}$ and 108.6 ${\mu}g$ $kg^{-1}$ in the streams and between 5.3${\mu}g$ $kg^{-1}$ and 87.3 ${\mu}g$ $kg^{-1}$ in the reservoir, and the values were highest in the muscle tissues. Levels of natural background levels of total mercury, even though the sampling number was few, averaged 23.6 ${\mu}g$ $kg^{-1}$ in the study sites. The individual and mean values in each system was not so high in terms of US EPA criteria of fish health and human health, indicating that the impact was minor in the study site. Further studies should be done for the determination of mercury levels in the systems.

일부지역 초등학생의 스트레스와 대처행위 측정 (Measurements of Stress and Coping with Stress Among School-Aged Children in the Chon-buk Area)

  • 정영숙;정승희
    • 한국학교보건학회지
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    • 제9권2호
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    • pp.185-195
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    • 1996
  • This study attempts to discover ways to prevent and cope with stress m primary school students, Specific, ally, we wish to investigate the sources of stress and to identify the variance and frequency of coping methods which have been used by the subjects. After examining the school children's list of items about stress and coping strategies by on open structure method, subjects ranked the seventy of stressor's and frequency of a coping strategies by closed structure method. A survey was done of 720 students who were from the 4th to 6th grade in 4 primary schools in the Chonbuk area from April 1st to May 30th, 1995. The major results obtained from this study were the following. 1. The sources of stress bad were classified in 57 items Among the 57 items, 'were school records' 'illness of parents' 'death of family members' 'meetings with trouble makers' ranked high ranking in the stress ratings. 2. Severity of stress. the mean total stress scores were 186.4 with 285 as the highest score. 3. The kinds of coping with stress using were classified in 35 items, Among the 35 items, 'wandering and walking alone' 'mood getting out of the in any way' 'trying to forget the stressor' 'were among the highest scored. 4. Frequency of coping with stress: mean total stress coping scores were 67.9 with 140 as the highest score. 5. Difference m stress and coping strategies between sex, age, living district and religion groups were examined. 1) Significant variables influencing stress scoring were sex (t=-2,29, p<.001) and grade (F=6.33, p<.001). 2) Significant variables influencing stress coping practice were residence (t=1.94, p<.05), sex (t=-3.17, p<.002) and religion (F=5,95, p<.0001).

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일부 치위생과 학생의 스트레스원과 대처방식에 관한 연구 (A study on the stressors and coping patterns of some dental hygiene students)

  • 박일순;이선희
    • 한국치위생학회지
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    • 제8권4호
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    • pp.251-263
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    • 2008
  • Purpose : The purpose of this study was to examine the stressors and coping patterns of dental hygiene students in a bid to boost the efficiency of guidance and counseling. Subjects and Method : The subjects in this study were 359 dental hygiene students from some colleges. After a survey was conducted, the collected data were analyzed with SPSS 13.0 program. Statistical data on frequency and percentage were obtained, and ANOVA and t-test were utilized. Findings : 1. The dental hygiene students investigated suffered the most stress with excessive workload, and anxiety about the national examination was the greatest stressor. Among the areas of stressors, school life put the most pressure on them(3.25). 2. The most dominant way for the dental hygiene students to handle stress was talking with friends(4.32). Out of the areas of stress-coping patterns, mental coping was most prevalent(2.94), and the least common stress-coping area was physical coping(2.23). 3. As for the relationship between the place where they were raised and stress-coping styles, physical coping and direct coping were more widespread among the students who were brought up in large urban communities than the others. Conclusion : As the dental hygiene students were different in stress-coping styles according to the place where they were grown, educators who nurture dental hygienists should offer customized education and counseling in consideration of where students were brought up.

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호텔직원의 핵심자기평가, 지각된 고객언어폭력 및 이직의도 간의 구조적 관계 (Structural Relationships among Frontline Hotel Employees' Core Self-evaluations, Perceived Customer Verbal Aggression and Turnover Intention)

  • 김태구;이계희
    • 한국조리학회지
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    • 제18권4호
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    • pp.100-117
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    • 2012
  • 본 연구의 목적은 일선 호텔직원들의 개인자원으로서 핵심자기평가(자아존중감, 일반화된 자아효능감, 통제위치 및 정서적 안정성), 직무스트레스 요인으로서 고객언어폭력(직무스트레스 요인)과 직무결과로서 이직의도 간의 구조관계를 분석하는 것이었다. 자료는 부산시내에 소재하는 10개의 특급호텔에 근무하는 일선직원들을 표본으로 하여 자기기입식 조사법에 의하여 수집되었다. 총 405부의 설문지가 최종 분석에 이용되었다. 본 연구는 연구모형과 연구가설들을 검증하기 위하여 구조방정식모형분석을 적용하였다. 가설화된 것처럼, 분석결과는 핵심자기평가가 고객언어폭력에 대한 지각과 이직의도를 경감시키는 것을 보여주었다. 고객언어폭력은 이직의도를 증폭시킨다는 결과를 보여주었다. 마지막으로, 실무적 시사점을 논의하였으며, 본 연구의 한계점을 제시하였고 향후 연구방향을 제안하였다.

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Correlation of Occupational Stress Index with 24-hour Urine Cortisol and Serum DHEA Sulfate among City Bus Drivers: A Cross-sectional Study

  • Du, Chung-Li;Lin, Mia Chihya;Lu, Luo;Tai, John Jen
    • Safety and Health at Work
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    • 제2권2호
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    • pp.169-175
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    • 2011
  • Objectives: The questionnaire of occupational stress index (OSI) has been popular in the workplace, and it has been tailored for bus drivers in Taiwan. Nevertheless, its outcomes for participants are based on self-evaluations, thus validation by their physiological stress biomarker is warranted and this is the main goal of this study. Methods: A cross-sectional study of sixty-three city bus drivers and fifty-four supporting staffs for comparison was conducted. Questionnaire surveys, 24-hour urine cortisol testing, and blood draws for dehydroepiandrosterone-sulfate (DHEA-S) testing were performed. The measured concentrations of these biological measures were logarithmically transformed before the statistical analysis where various scores of stressor factors, moderators, and stress effects of each OSI domain were analyzed by applying multiple linear regression models. Results: For drivers, the elevated 24-hour urine cortisol level was associated with a worker's relationship with their supervisor and any life change events in the most recent 3 months. The DHEA-S level was higher in drivers of younger age as well as drivers with more concerns relating to their salary and bonuses. Non-drivers showed no association between any stressor or satisfaction and urine cortisol and blood DHEA-S levels. Conclusion: Measurements of biomarkers may offer additional stress evaluations with OSI questionnaires for bus drivers. Increased DHEA-S and cortisol levels may result from stressors like income security. Prevention efforts towards occupational stress and life events and health promotional efforts for aged driver were important anti-stress remedies.

혈액투석 환자들의 Minor Stress, 대처방식 및 삶의 질 (Minor Stress, Coping Skill and Quality of Life in Patients with Hemodialysis)

  • 양재원;이문수;박상욱;오소영;고영훈;권영주;조숙행
    • 정신신체의학
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    • 제16권1호
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    • pp.38-46
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    • 2008
  • 연구목적 : 본 연구는 말기 신질환으로 혈액투석을 받는 환자들에서 일상 생활에서 흔히 경험하는 경한 스트레스의 요인(minor stressor)의 빈도와 영향 및 취약성, 스트레스 대처방식의 특성, 주관적인 삶의 질의 관계를 살펴보는 것을 목적으로 하였다. 이를 통해 말기 신질환 환자들의 정신건강 및 삶의 질 향상을 위한 기초 자료를 제공하려 한다. 방법 : 혈액투석을 받는 환자 77명을 대상으로 하였다. 일상생활사건인 minor stressor와 관련된 스트레스의 정도와 대응기전을 나타내는 일상생활 스트레스 척도(Daily Stress Inventory Korean version, K-DSI)와 스트레스 대처방식 질문지(Ways of Coping Checklist)를 각각 사용하여 평가하였다. 삶의 질은 간편형 세계보건기구의 삶의 질 척도(World Health Organization Quality of Life Assessment Instrument)로 평가하였다. 결과 : 연구 참여인원은 77명(남자 37명, 여자 40명)이었고, 평균 연령은 $55.92{\pm}13.71$세였다. K-DSI의 사건, 영향, 영향/사건 비 점수는 평균 $29.06{\pm}21.57$점, $88.69{\pm}75.88$점, 그리고 $2.92{\pm}1.11$점으로 K-DSI의 규준 점수와 비교하여 높은 점수를 보였다. 대인관계, 개인능력, 인지, 환경 및 기타 스트레스의 다섯 하위요인별 점수도 규준 점수보다 높았으며, T 점수 비교에서는 사건 점수가 각각 54, 53, 81, 50, 57, 영향 점수는 각각 71, 88, 94, 69, 53으로 그 중 인지 스트레스 요인 점수가 사건, 영향 점수 모두 현저히 높았다. 스트레스에 대한 취약성을 나타내는 K-DSI의 영향/사건 비와 대처 방식 중 소극적 대처 방식 점수는 유의한 양의 상관을 보였다(소망추구 사고, 정서중심 대처 각각 r=0.431, r=0.225, p<0.05). 또한, 적극적 대처방식 중에서 문제해결 대처방식 점수는 삶의 질 척도의 신체건강(r=.294, p<0.01), 심리(r=.300, p<0.01), 사회관계(r=.233, p<0.05), 및 환경 하위요인(r=.293, p<0.05)과 유의한 양의 상관을 보였다. 결론 : 혈액 투석을 받는 만성 신질환자들은 일반 인구에 비해 경한 스트레스 요인(minor stressor)에 대한 영향을 현저히 많이 받고, 적극적 대처방식인 문제중심 대처와 삶의 질은 양의 상관을 보인다. 또한, 경한 스트레스 요인(minor stressor)에 대한 취약성이 높을수록 적극적 대처방식보다는 정서중심 및 소망추구 등의 소극적 대처방식을 더 많이 사용하고 있다. 혈액 투석 환자들의 스트레스를 평가할 때 일상생활에서 흔히 경험하는 경한 스트레스 요인에 대한 스트레스(minor stress) 평가와 대처방식이 함께 고려되어야 할 것이다. 더 나아가 혈액투석 환자들의 장기 치료 접근에 있어서 스트레스 관리와 대처기술 훈련을 포함한 치료가 병행되어야 환자들의 삶의 질 향상에 효과가 있을 것으로 예상된다.

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