• 생물정신의학
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• 제15권1호
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• pp.14-22
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• 2008

우울 장애는 유전적 요인과 함께 환경적 요인이 복합적으로 작용하는 정신 장애이다. 본 연구에서는 세로토닌 체계와 연관된 유전적 요인과 생활사건과 같은 환경적 요인이 초기 성인기 우울 장애 발현에 미치는 영향을 조사함으로써 우울 장애의 원인론에 있어 유전자${\times}$환경 상호작용을 설명할 수 있는 자료를 제시하고자 하였다. 534명의 대학 신입생을 종적으로 추적 조사하여 생활사건 빈도와 중요도, 우울 척도와 불안 척도를 조사하였으며 전화 면담을 통해 DSM-IV 우울 장애 여부를 확인하였다. 최종적으로 150명이 연구에 포함되었으며 이전 연구로 확인된 TPH1 유전형과 함께 보관되어 있던 대상군의 DNA를 이용하여 SNaPshot$^{TM}$ 방식으로 TPH2, 5HTR2A 유전자를 추가 분석하였다. 유전자 정보와 생활사건 특성이 우울 증상에 미치는 영향을 확인하기 위해 로지스틱 회귀 분석과 상관 분석, 카이 자승 분석을 사용하였다. TPH1 유전형 중 C 대립 유전자가 존재하지 않는 집단과 달리 C 대립 유전자가 존재하는 집단에서는 생활사건 빈도가 우울 장애 유발에 유의한 영향을 미쳤다. 이러한 영향은 다른 대립 유전자나 유전형을 보이는 집단에서는 관찰되지 않았다. 본 연구의 결과는 TPH1 유전형은 생활사건 이후 우울 장애 발생의 유의미한 예측 요인임을 시사한다. 이는 우울 장애의 유전${\times}$환경 상호작용에 TPH1 유전자가 작용하고 있음을 제시한다.

• 한국간호교육학회지
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• 제21권2호
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• pp.237-245
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• 2015

Purpose: The purpose of the study was to explore the levels of self-awareness, assertiveness, life stress, and empathy in nursing students and identify influential factors on empathy. Methods: A predictive correlational design was used. The data was collected by questionnaires from a convenience sample of 319 nursing students in 2014 in Korea. The data was analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation coefficients, and stepwise multiple regression. Results: The mean items scores of self-awareness, assertiveness, life stress, and empathy were 3.49, 3.02, 2.20 and 3.58, respectively, of a possible score ranging from 1 to 5. Empathy significantly differed by gender, grade, satisfaction with nursing as a major, and clinical practice experience. Empathy was correlated with self-awareness and interpersonal relationship stress. As a result of multiple regression analysis, empathy accounted for 20.1% of the variance by self-awareness, gender, clinical practice experience and interpersonal relationship stress. The most important factor was self-awareness, which explained 11.6% of the variation. Conclusion: The results of the study reveal that strengthening self-awareness and relieving interpersonal relationship stress ought to be integrated in developing effective educational intervention for enhancing empathy in nursing students.

• 생태와환경
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• 제45권4호
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• pp.420-443
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• 2012

An Individual-Based Model (IBM) was developed by employing natural and toxic survival rates of individuals to elucidate the community responses of benthic macroin-vertebrates to anthropogenic disturbance in the streams. Experimental models (dose-response and relative sensitivity) and mathematical models (power law and negative exponential distribution) were applied to determinate the individual survival rates due to acute toxicity in stressful conditions. A power law was additionally used to present the natural survival rate. Life events, covering movement, exposure to contaminants, death and reproduction, were simulated in the IBM at the individual level in small (1 m) and short (1 week) scales to produce species abundance distributions (SADs) at the community level in large (5 km) and long (1~2 years) scales. Consequently, the SADs, such as geometric series, log-series, and log-normal distribution, were accordingly observed at severely (Biological Monitoring Working Party (BMWP<10), intermediately (BMWP<40) and weakly (BMWP${\geq}50$) polluted sites. The results from a power law and negative exponential distribution were suitably fitted to the field data across the different levels of pollution, according to the Kolmogorov-Smirnov test. The IBMs incorporating natural and toxic survival rates in individuals were useful for presenting community responses to disturbances and could be utilized as an integrative tool to elucidate community establishment processes in benthic macroin-vertebrates in the streams.

• 대한가정학회지
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• 제47권6호
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• pp.21-38
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• 2009

This study examined the resilience factors of multi-cultural families using depth interviews. Thirty-one multi-cultural families(totaling 98 individuals) were interviewed on a range of issues, including the process of marriage, the attitude of international marriage, family relations, social networks, the process of social adaptation, and their needs for specific social services. The resilience theory was used to categorize resilience factors, multi-cultural families. Analysis of results from depth interviews identified three broad resilience factors. The first was related to for belief systems which included 'family's common goal', The second was related to family functioning systems which included 'family cohesion', 'family adaptability', and 'satisfaction for role-expectation'. The third was related to social networking which included 'satisfaction from social activities'. These resilience factors helped multi-cultural families cope with stressful events and risk situations related to every day life. Results from this study imply that multi-cultural families possess the abilities to lead a meaningful and healthy life-style regardless of obstacles such as communication difficulties, cultural differences, and societal stigma.

• 정신신체의학
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• 제6권2호
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• pp.221-227
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• 1998

Although there has been a considerable research in psychoneuroendocrinology, particularly in relation to the biology of mood disorders, there has been a paucity of research regarding the effects of psychological factors on endocrine diseases. Of the existing literature, the most research is focused on diabetes mellitus, graves' disease. Especially diabetes appears to be the only endocrine disease that has been the focus of recent research studies. Most of the studies had retrospective designs or several methodological flaw. There has been no consistent results demonstrating that psychological factors affect the onset of diabetes mellitus. Several studies have suggested that psychological factors affect the course of diabetes. A small number of studies showed some evidence that psychological stress was associated with changes in glucose regulation in a subset of diabetic patients. There was also evidence to suggest that some temperament and coping skill influence glycemic control in child, adolescent diabetics. Studies of behavioral or psychosocial intervention on diabetic control have been small and have produced mixed results. There was a few controlled study suggested that stressful life events might be a causal role in Cushing's disease and Graves'disease, but there is no presently sufficient evidence to suggest that psychological factors affect the onset and the course of Cushing's disease and Graves' disease. In future, there is need for a well-designed biopsychosocial research with prospective designs, well defined patient population and control groups to study the relationship between psychological factors and endocrine diseases.

• 여성건강간호학회지
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• 제18권3호
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• pp.223-235
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• 2012

Purpose: This study was designed to examine the relationships among daily hassles, social support, entrapment and mental health status in relation to gender in university students. Methods: Data were collected via a self- administered questionnaire from 118 male and 98 female college students in Kangwon province. Data were analyzed using SPSS/WIN 18.0 program for descriptive statistics, t-test, ANOVA, Pearson correlation, and stepwise multiple regression. Results: There were significant differences in daily hassles, entrapment and depression between male and female group. Also, there were significant relationship between entrapment and mental health status (i.e. depression, anxiety, hostility, somatization) in both groups. In male students, internal entrapment was the significant predictor of depression and anxiety, and external entrapment was the significant predictor of hostility and somatization whereas, in female students external entrapment was the significant predictor of depression, and internal entrapment was the significant predictor of anxiety, hostility and somatization. Conclusion: These results suggest that entrapment is an important factor for psychological maladaptation due to stressful life events. Therefore, strategies that reduce perception of entrapment according to gender should be developed for psychological adaptation.

• 가정과삶의질연구
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• 제27권2호
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• pp.305-316
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• 2009

The purpose of this study was to investigate how children from low-income families perceived their family strength, ego-resilience and school adjustment. The relative magnitude of effects of family strength, ego-resilience and school adjustment were compared. Data were collected from 217 children in grade 4 through 6 who were attending local child welfare centers located in Seoul, Korea. The key research findings were as follows. Ego-resilience and perceived family strength were related to school adjustment among children in poverty. The relatively greater effect of ego-resilience implied that programs for children in poverty need to focus on developing interpersonal relationship skills or coping strategies designed to enable children from disadvantaged environments to deal with stressful events and to promote their ego-resilience. Additionally, the recovery or enhancement of family strength and ego-resilience will be effective at protecting and solving various adaptive problems that children from low-income families may experience at school.

• 아동학회지
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• 제19권2호
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• pp.49-64
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• 1998

The theoretical process model was used to study problem behavior of children growing up at-risk. A sample of 339 children living in at-risk families were selected from among 2, 134 children in grades 4, 5, and 6 of five elementary schools in Seoul. The instruments were five risk factor scales and four protective factor scales. The Child Behavior Checklist was also used. The results of the hypothetical model of children at-risk showed that the factor of socioeconomic status led to positive child rearing attitudes in mothers, which is turn influenced children's problem behavior indirectly. In contrast, stressful life events and mother's depression influenced children's problem behavior directly. However, negative family functioning, marital discord and father's depression did not influence mother's child rearing attitudes or children's problem behavior. Mother's child rearing attitudes directly influenced children's social competence and academic achievement and indirectly influenced their problem behavior. Academic achievement did not influence problem behavior directly, but social competence influenced it directly. Mother's child rearing attitude was the most significant factor affecting children's adaptation.

• 아동학회지
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• 제13권2호
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• pp.175-188
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• 1992

This study investigated the relation between stressful life events and adjustment in elementary school children, with particular emphasis on the potential main and stress-buffering effects of social support and social problem solving skills. 4-6 graders (N=170) completed the Social Support Appraisals Scale(SSAS) and social problem solving skills task. The SSAS is a 31-item measure that taps the child's perceptions or appraisals of family, peer, and teacher support. Their parents provided ratings of stress in the child's environment and ratings of the child's behavioral adjustment. Teachers provided ratings of the child's behavioral and academic adjustment. Hierarchical multiple regression analyses and graphic display were used to analyze the data. The major findings were that (1) The results for parent-rated problems supported a stress-buffering model for family support and problem solving. (2) The results for teacher-rated problems were consistent with the stress-buffering model of social support. (3) The results for grade-point average supported a main effect model for problem solving. peer support, and family support. In addition, teacher support had the strongest stress-buffering effect on grade-point average.

• 중환자간호학회지
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• 제8권2호
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• pp.55-65
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• 2015

Purpose: The purpose of this study was to identify the attributes, antecedents, and consequences of post-intensive care syndrome. Methods: The study was conducted in accordance with Walker and Avant's conceptual analysis process. We searched the Medline, ProQuest, Google scholar, NANET (Korean National Assembly Library), and RISS (Korean Education and Research Information Service) databases resulting in 29 studies for in-depth review. Results: The attributes of post-intensive care syndrome include (1) new or worsening impairment persisting after discharge, (2) physical impairment, (3) psychological impairment, (4) cognitive impairment, and (5) symptom experience. The antecedents of the concept include a critical condition that requires intensive care, stressful events, immobility, sedation, delirium, insomnia, frailty, and invasive procedures. The consequences of post-intensive care syndrome are increased dependency in activities of daily life, decreased social interaction, delayed return to previous occupation, decreased quality of life, familial post-intensive care syndrome, and readmission/death. Conclusion: The concept of post-intensive care syndrome has multifaceted and integrative features. Further research needs to be conducted to develop a measurement tool that reflects the attributes of the concept and to develop multidisciplinary interventions to prevent post-intensive care syndrome.