• 제목/요약/키워드: Stress- ratio

검색결과 4,014건 처리시간 0.032초

Lactobacillus casei Zhang Prevents Jejunal Epithelial Damage to Early-Weaned Piglets Induced by Escherichia coli K88 via Regulation of Intestinal Mucosal Integrity, Tight Junction Proteins and Immune Factor Expression

  • Wang, Yuying;Yan, Xue;Zhang, Weiwei;Liu, Yuanyuan;Han, Deping;Teng, Kedao;Ma, Yunfei
    • Journal of Microbiology and Biotechnology
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    • 제29권6호
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    • pp.863-876
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    • 2019
  • Farm animals such as piglets are often affected by environmental stress, which can disturb the gut ecosystem. Antibiotics were commonly used to prevent diarrhea in weaned piglets, but this was banned by the European Union due to the development of antibiotic resistance. However, the use of probiotics instead of antibiotics may reduce the risk posed by pathogenic microorganisms and reduce the incidence of gastrointestinal diseases. Therefore, this study was conducted to investigate the effects of Lactobacillus casei Zhang on the mechanical barrier and immune function of early-weaned piglets infected using Escherichia coli K88 based on histomorphology and immunology. Fourteen-day-old weaned piglets were divided into a control group and experimental groups that were fed L. casei Zhang and infected with E. coli K88 with or without prefeeding and/or postfeeding of L. casei Zhang. The L. casei Zhang dose used was $10^7CFU/g$ diet. Jejunum segments were obtained before histological, immunohistochemical, and western blot analyses were performed. In addition, the relative mRNA expression of toll receptors and cytokines was measured. Piglets fed L. casei Zhang showed significantly increased jejunum villus height, villus height-crypt depth ratio, muscle thickness, and expression of proliferating cell nuclear antigen and tight junction proteins ZO-1 and occludin. The use of L. casei Zhang effectively reduced intestinal inflammation after infection. We found that L. casei Zhang feeding prevented the jejunum damage induced by E. coli K88, suggesting that it may be a potential alternative to antibiotics for preventing diarrhea in early-weaned piglets.

트랙터 부착형 양파수확기의 작업 속도에 따른 견인 부하와 구조 안정성에 관한 실험적 연구 (Experimental Study on the Drawbar Pull and Structural Safety of an Onion Harvester Attached to a Tractor)

  • 신창섭;김준희;하유신;박두산
    • 한국기계가공학회지
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    • 제18권4호
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    • pp.16-25
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    • 2019
  • Recently, due to labor shortages in rural areas within South Korea, the demand for upland-field machinery is growing. In addition, there is a lack of development of systematic performance testing of upland-field machinery. Thus, this study examined structural safety and drawbar pull based on soil properties, as a first step for systematic performance testing on the test bed. First, the properties of soil samples from 10 spots within the experimental site were examined. Second, the strain was measured and converted into stress on 8 points of an onion harvester that are likely to fail. More specifically, the chosen parts are linked to the power, along with the drawbar pull, using a 6-component load cell equipped between the tractor and the onion harvester. The water content of the soil ranged between 5.7%-7.5%, and the strength between 250-1171 kPa. The test soil was subsequently classified into loam soil based on the size distribution ratio of the sieved soil. The onion harvester can be considered as structurally safe based on the derived safety factor and the drawbar pull of 115-1194 kgf, according to the working speed based on agricultural fieldwork.

Prestress evaluation in continuous PSC bridges by dynamic identification

  • Breccolotti, Marco;Pozzaa, Francesco
    • Structural Monitoring and Maintenance
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    • 제5권4호
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    • pp.463-488
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    • 2018
  • In the last decades, research efforts have been spent to investigate the effect of prestressing on the dynamic behaviour of prestressed concrete (PSC) beams. Whereas no agreement has been reached among the achievements obtained by different Researchers and among the theoretical and the experimental results for simply supported beams, very few researches have addressed this problem in continuous PSC beams. This topic is, indeed, worthy of consideration bearing in mind that many relevant bridges and viaducts in the road and railway networks have been designed and constructed with this structural scheme. In this paper the attention is, thus, focused on the dynamic features of continuous PSC bridges taking into account the effect of prestressing. This latter, in fact, contributes to the modification of the distribution of the bending stress along the beam, also by means of the secondary moments, and influences the flexural stiffness of the beam itself. The dynamic properties of a continuous, two spans bridge connected by a nonlinear spring have been extracted by solving an eigenvalue problem in different linearized configurations corresponding to different values of the prestress force. The stiffness of the nonlinear spring has been calculated considering the mechanical behaviour of the PSC beam in the uncracked and in the cracked stage. The application of the proposed methodology to several case studies indicates that the shift from the uncracked to the cracked stage due to an excessive prestress loss is clearly detectable looking at the variation of the dynamic properties of the beam. In service conditions, this shift happens for low values of the prestress losses (up to 20%) for structure with a high value of the ratio between the permanent load and the total load, as happens for instance in long span, continuous box bridges. In such conditions, the detection of the dynamic properties can provide meaningful information regarding the structural state of the PSC beam.

반순환여과시스템에서 오존 유래 잔류산화물 농도에 따른 넙치(Paralichthys olivaceus)의 성장과 생리학적 변화 (Growth Performance and Physiological Changes of Olive Flounder Paralichthys olivaceus by Concentration of Ozone Produced Oxidants in Semi-RAS)

  • 정상명;박우근;박정환;김재원;김병기
    • 한국수산과학회지
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    • 제51권6호
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    • pp.688-696
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    • 2018
  • This study investigated the effects of ozone-produced oxidants (OPO) on the growth, hematology, and histology of olive flounder Paralichthys olivaceus (average weight 500 g), raised in an ozonated semi-recirculating aquaculture system. The system was ozonated to maintained OPO concentrations of 0.004 (Control), 0.014 (OPO15), and 0.025 (OPO25) mg $Cl_2/L$ in culture tanksfor 26 days. The specific growth rate, feed conversion ratio, and survival rate did not significantly differ among the groups (P>0.05), while the daily feeding rate decreased OPO-dose-dependently (P<0.05). OPO appeared to affect the gill, hepatopancreas, and kidney tissues of fish from ozonated tanks. Hematologically, OPO affected some blood indices. The levels of chloride, glucose, glutamic oxaloacetic transaminase, and glutamic pyruvic transaminase were significantly increased in the ozonated groups, while the total cholesterol and cortisol decreased dose-dependently. These results imply that long-term exposure of olive flounder to an OPO concentration ${\geq}0.014mg\;Cl_2/L$ might result in damage to the gill, hepatopancreas, and kidney tissues and cause physiological stress, albeit with no apparent short-term effects on growth or survival.

한계상태 Mohr Coulomb 소성 모델을 활용한 콘관입시험의 수치적 모사 (Numerical Simulation of Cone Penetration Tests in Sand Ground Using Critical State Mohr Coulomb Plasticity Model)

  • 우상인;정충기
    • 한국지반공학회논문집
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    • 제35권2호
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    • pp.37-51
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    • 2019
  • 본 연구는 사질토 지반에서 수행되는 콘관입시험의 수치적 모사에 초점을 맞추고 있다. 지반은 한계상태 토질역학을 바탕으로 수정된 한계상태 Mohr Coulomb 소성 모델로 모사하였다. 한계상태 Mohr Coulomb 모델에서 팽창각은 상수가 아닌 현재상태와 한계상태 사이의 위상차의 함수로 표현된다. 수치적으로 콘관입시험은 대변위 해석을 요구하며, 이를 Lagrangian 유한요소법으로 해석하기 위해 관입 유도체 개념을 적용한 축대칭 조건 유한요소법을 이용하였다. 캘리브레이션 챔버에서 수행된 콘관입시험을 한계상태 Mohr Coulomb 모델을 이용하여 본 논문에서 제안된 유한 해석 기법을 적용한 결과, 실험 결과와 유사한 결과를 얻을 수 있었다.

Field test and research on shield cutting pile penetrating cement soil single pile composite foundation

  • Ma, Shi-ju;Li, Ming-yu;Guo, Yuan-cheng;Safaei, Babak
    • Geomechanics and Engineering
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    • 제23권6호
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    • pp.513-521
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    • 2020
  • In this paper, due to the need for cutting cement-soil group pile composite foundation under the 7-story masonry structure of Zhenghe District and the shield tunnel of Zhengzhou Metro Line 5, a field test was conducted to directly cut cement-soil single pile composite foundation with diameter Ф=500 mm. Research results showed that the load transfer mechanism of composite foundation was not changed before and after shield tunnel cut the pile, and pile body and the soil between piles was still responsible for overburden load. The construction disturbance of shield cutting pile is a complicated mechanical process. The load carried by the original pile body was affected by the disturbance effect of pile cutting construction. Also, the fraction of the load carried by the original pile body was transferred to the soil between the piles and therefore, the bearing capacity of composite foundation was not decreased. Only the fractions of the load carried by pile and the soil between piles were distributed. On-site monitoring results showed that the settlement of pressure-bearing plates produced during shield cutting stage accounted for about 7% of total settlement. After the completion of pile cutting, the settlements of bearing plates generated by shield machine during residual pile composite foundation stage and shield machine tail were far away from residual pile composite foundation stage which accounted for about 15% and 74% of total settlement, respectively. In order to reduce the impact of shield cutting pile construction on the settlement of upper composite foundation, it was recommended to take measures such as optimization of shield construction parameters, radial grouting reinforcement and "clay shock" grouting within the disturbance range of shield cutting pile construction. Before pile cutting, the pile-soil stress ratio n of composite foundation was 2.437. After the shield cut pile is completed, the soil around the lining structure is gradually consolidated and reshaped, and residual pile composite foundation reaches a new state of force balance. This was because the condensation of grouting layer could increase the resistance of remaining pile end and friction resistance of the side of the pile.

Effects of soft pellet creep feed on pre-weaning and post-weaning performance and intestinal development in piglets

  • Chen, Hao;Wang, Chunwei;Wang, You;Chen, Yilin;Wan, Meng;Zhu, Jiadong;Zhu, Aixia
    • Animal Bioscience
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    • 제34권4호
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    • pp.714-723
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    • 2021
  • Objective: This study aimed to determine the effects of soft pellet creep feed (SPCF) on growth performance and intestinal development in piglets. Methods: A total of 18 sows and their litters of crossbred piglets (14±2 days, 3.73±0.72 kg) were assigned to one of three dietary groups receiving i) powder creep feed (PCF), ii) hard pellet creep feed (HPCF) or iii) SPCF during the pre-weaning period. After weaning, piglets were selected for continuous evaluation of the three diets on growth performance and intestinal health. Results: In the pre-weaning period, the average daily feed intake and average daily dry matter intake were significantly higher in the SPCF group than the HPCF group (p<0.05). In the post-weaning and entire experimental period, the different diets had no significant effect on growth performance. At 10 d after weaning, the serum glucose concentration was lower in the SPCF group (p<0.05) than the other groups; a higher (p<0.05) villus height and lower (p<0.05) crypt depth in the jejunum were also observed in the SPCF group than the other groups; Meanwhile, in the duodenum and jejunum, the SPCF group had a higher (p<0.05) villus height to crypt depth ratio than the other groups; Furthermore, the higher (p<0.05) threshold cycle values of lactic acid bacteria and lower (p<0.05) threshold cycle values of Clostridium, Enterobacter and Escherichia coli were also observed in the SPCF group, and the sucrase and maltase activity was higher (p<0.05) in the SPCF group than the other groups in duodenum and ileum. Conclusion: The SPCF improved pre-weaning feed intake and decreased the negative effects of weaning stress in the intestine in piglets.

황색산화철을 포함하는 혼합형 고체추진제의 특성에 관한 연구 (2) (Composite Solid Propellants for Propulsion System Including a Yellow Iron Oxide (2))

  • 박성준;김경민;박정호;노태호;최성한
    • 한국추진공학회지
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    • 제24권3호
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    • pp.12-17
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    • 2020
  • 황색 산화철을 적용한 추진제의 기계적 특성은 적색산화철을 적용한 추진제와 비교하여 기계적물성이 다소 증가하였다. 또한 황색산화철을 적용한 추진제는 두 종류의 AP 입자를 사용하였으며 총량을 유지하고 작은 입자의 AP 비율 증가 시 연소속도가 증가하였다. 황색산화철을 첨가한 추진제는 압력 지수 값이 0.5인 17.5 mm/sec 이하의 운용조건에서 추진기관에 적용 가능하다. 혼합 믹서 Scale-up 시연소속도 감소, 최대인장강도 감소, 최대인장강도에서의 연신율은 증가하였다. 황색산화철은 내열재/라이너/추진제 사이의 접착력에는 큰 영향을 끼치지 않는다.

Growth, carcass traits, immunity and oxidative status of broilers exposed to continuous or intermittent lighting programs

  • Ghanima, Mahmoud M. Abo;El-Hack, Mohamed E. Abd;Abougabal, Mohammed Sh.;Taha, Ayman E.;Tufarelli, Vincenzo;Laudadio, Vito;Naiel, Mohammed A.E.
    • Animal Bioscience
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    • 제34권7호
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    • pp.1243-1252
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    • 2021
  • Objective: An experiment was conducted to investigate the continuous and intermittent lighting program effects on terms of the productive performance, carcass traits, blood biochemical parameters, innate immune and oxidative status in broiler chicks. Methods: A total of 600 Cobb-500 one day old chicks were randomly allocated into six equal groups (100 chicks per treated group with five replicates of 20 chicks each) based on lighting program; 22 continuous lighting (22 C), 11 h lighting+1 darkness twice daily (11 L/1 D), 20 h continuous lighting (20 C), 5 h lighting+1 darkness four times daily (5 L/1 D), 18 h continuous lighting (18 C) and the final group subjected for 3 h lighting+1 h darkness six times daily (3 L/1 D). The experimental period lasted 42 days. Results: Compared with those under the intermittent light program, broiler chicks exposed to continuous lighting for 22 h had significant improvement in live body weight and carcass (dressing and breast percentage) measured traits. Though reducing lighting hours significantly reduced feed intake and feed conversion ratio values. Different lighting programs revealed no significant effect on all blood biochemical parameters. Oxidative stress and innate immunity parameters significantly enhance by reducing lighting hours (3L/1D). Conclusion: The findings suggest that reducing lighting hours up to 3L/1D would be more useful in enhancing feed efficiency, innate immunity, and oxidative status compared with continuous lighting programs on broilers.

Lower Nutrient Intakes and Periodontitis: Findings from the Korea National Health and Nutrition Examination Surveys

  • 이민선;한동헌;김미선
    • 대한치위생과학회지
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    • 제4권1호
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    • pp.39-51
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    • 2021
  • Background: Limited information is available regarding the associations of various nutrients and periodontitis in Korea. Furthermore, these associations have been controversial in previous studies. Therefore, the present study aimed to evaluate the associations between several nutrients and periodontitis. Methods: Pooled data from the 2007~2010 and 2012 Korea National Health and Nutrition Examination Surveys (KNHANES) were used for the present study. Periodontitis was defined using the World Health Organization (WHO) Community Periodontal Index. All participants completed the Food Frequency Questionnaire (FFQ), which was analyzed using CAN-Pro 4.0. Vitamins A, B1, B2, and C, iron, phosphorus, calcium, and protein were selected for analysis. Multiple logistic regression analyses were used to estimate the odds ratios (ORs) for periodontitis. Results: Lower intake of phosphorus (adjusted odds ratio [AOR] = 1.86), calcium (AOR = 1.25), and protein (AOR = 1.52) were associated with periodontitis in males, and lower intake of vitamins A (AOR = 1.32), B1 (AOR = 1.21), B2 (AOR = 1.24), and C (AOR = 1.21), iron (AOR = 1.25), phosphorus (AOR = 1.33), and protein (AOR = 1.27) showed significant relationships with periodontitis in females. In the sociodemographic, somatic, and health behavior-adjusted models, lower phosphorus (AOR = 2.68) and protein (AOR = 1.68) intake in younger males, and lower vitamin A intake (AOR = 1.37) in middle-aged females were significantly associated with periodontitis. Conclusions: The results of the present study demonstrated a significant association between periodontitis and nutrient intake. To avoid an insufficient nutrient supply for a patient with periodontal disease, the patient's diet should be closely monitored.