• 생명과학회지
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• 제26권9호
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• pp.1088-1096
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• 2016

중등도 온열요법이 종양세포에 대한 세포독성, 종양혈관에 미치는 영향 및 면역학적 영향 등 다양한 항종양 활성을 가지고 있음에도 불구하고, 중등도 온열요법은 그 자체만으로는 항암효과가 뚜렷하지 않아, 방사선치료나 항암제 치료와 병용하여 암치료에 사용되고 있으면서, 심각한 부작용이 없이 어느 정도의 긍정적인 효과를 보이고 있다. 모든 연구에서 긍정적인 결과를 보이지 못한 것은 열충격 반응 그 자체가 온열요법의 항암효과를 방해하기 때문이다. 그러므로 온열요법의 효과를 증가시키기 위해서는 온열요법의 항암효과에 대한 부정적인 영향을 제거해야 한다. 암세포뿐만 아니라 혈관, 면역 세포 및 결체조직 등을 포함하고 있는 종양조직의 열 스트레스에 대한 반응은 매우 복잡하지만, 임상적으로 사용되고 있는 약물 중 열 스트레스 반응을 조절할 수 있는 약물들이 암환자의 온열요법 치료 효과를 개선시킬 수 있는 지에 대한 연구가 필요하다. 이 종설에서는 현재 임상에서 사용하고 있는 온열요법 장치로서 최신의 기술이며, 중등도 온도가 정상 조직에 대한 부작용 없이 기존 치료법의 효과를 증가시킬 수 있기 때문에, 비침습적 체외용 고주파 중등도 온열요법을 중심으로 다룬다.

• 치위생과학회지
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• 제14권2호
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• pp.87-93
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• 2014

Dental plaque resides passively at a site and makes an active contribution to the maintenance of health. The bacterial composition of plaque remains relatively stable despite regular exposure to minor environmental stress. This stability, homeostasis is due to a dynamic balance of microbial interactions. However, the homeostasis can break down, leading to shifts in the balance of the microflora. This change can be a sign of initial dental caries. It is proposed that disease can be prevented or treated not only by targeting the putative pathogens but also by interfering with the processes that drive the breakdown in homeostasis. It is essential to understand the plaque as a mixed species biofilm. In this essay I reviewed an extension of the caries ecological hypothesis to explain the relation between dynamic changes in the phenotypic/genotypic properties of plaque bacteria and the demineralization and remineralization balance of the dental caries process. We will have the strategies to impact significantly on clinical practice as understanding dental biofilm.

• 예술인문사회 융합 멀티미디어 논문지
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• 제9권8호
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• pp.569-576
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• 2019

본 연구는 재가요양보호사의 직무스트레스와 이직의도와의 관계에서 직업의식 매개효과를 검증하고, 그 결과를 기초하여 재가요양보호사의 이직의도를 감소시키려는 목적으로 수행하게 되었다. 연구대상은 서울·경기지역에서 일하고 있는 재가요양보호사 447명을 대상으로 하였다. 연구목적을 위해 자료분석은 SPSS 통계패키지를 활용하여 기술분석과 상관관계 분석 및 다중공선성 확인 후 매개효과를 검증하였다. 분석결과 첫째, 재가요양보호사가 연령이 낮고, 월가구소득이 높을수록 이직의도가 높을 것으로 나타났다. 둘째, 재가요양보호사가 직무스트레스를 높게 인식할수록 이직의도가 높아지는 것으로 나타났다. 셋째, 직업의식이 높을수록 이직의도는 낮게 나타났다. 넷째, 재가요양보호사의 직무스트레스는 직업의식을 부분 매개하여 이직의도에 통계적으로 유의미한 영향을 주는 것으로 나타났다. 이상의 결과를 토대로 재가요양보호사의 이직을 예방하고 노인돌봄 서비스의 질을 향상시키기 위한 임상적·정책적 실천에 대한 제언을 하였다.

• Toxicological Research
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• 제30권1호
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• pp.45-48
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• 2014

Helicobacter pylori (H. pylori) is the most important factor of gastric disease in clinical practice. Moreover, smoking, stress and a poor diet may be additive factors for gastric damage. With these factors, increasing infection of H. pylori triggers gastritis, gastric ulcers and gastric cancer. To develop a new protective agent, we are concerned with plant-derived extract. The extract of Coptis chinensis (C. chinensis) and its constituents were investigated to assess their protective activities against gastric damage. The C. chinensis extract showed a scavenging effect against 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and superoxide radicals, inhibition of H. pylori colonization and antiulcerogenic activities in rat. In particular, palmatine derived from C. chinensis was found to be the novel protective agent. It is better than the C. chinensis extract, berberine, a well-known constituent of C. chinensis. We suggest that palmatine from the root cortex of C. chinensis may be a good candidate for the development of new pharmaceuticals to prevent gastric disease.

• 대한간호학회지
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• 제7권2호
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• pp.107-116
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• 1977

It is a well accepted fact that mental and physical health of nurses has a direct bearing or influence in their practice in the nursing profession. Recently, with this view in mind, the study of the mental and physical health of nurses has attracted the attention of many especially those in research hospitals. According to Soon Hyang Cha(1974) a nurse in clinical practice or service has a daily energy consumption of 39% and San Cho Chun (1974) asserts that Nurses'duties are more demanding on her emotionally than on her nursing technical skills. Many more studies has been made to this effect, here and abroad and similarly stressed the importance of mental and physical health for nurses. This study was made in an attempt to analyze the trend or tendency of the mental and physical health of nurses by employing the Cornell Medical Index (CMI) method. The data has been collected from May 1977 to November 1977, 200 nurses from 8 University hospitals and 200 nurses from general hospitals in Seoul, Theses who participated were selected at random. The data were tabulated and comparison made. The results were as follows : 1. Among nurses, the analysis based on the length of experience, it is apparent that, the longer or more experience one ha s, the more complaints they have. 2 The longer the nurses are engaged in nursing practice, the more they have problems in their digestive, musculoskeletal, respiratory and nervous systems and are more prone to diseases, and get tired easier than those of shorter experience. But on the other hand it could be seen that younger nurses or nurses with less experience in the profession are more melancholic and prone to stress than those with longer experience.

• 대한한의학회지
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• 제27권4호
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• pp.215-224
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• 2006

Objectives : In order to apply useful data to clinical practice, we undertook this study and tried to find factors related with sequelae of facial palsy in relation with patients' age and gender distribution, past history with the disease, condition before onset, duration of recovery time, existence of remaining sequelae, types of the sequelae, and duration for sequelae to disappear. Methods : We evaluated patients' condition (fatigue, stress, chills, cold and so on), past history (diabetes mellitus, hypertension, stroke, herpes zoster, cancer and so on), duration of recovery time, types of the sequelae, age and sequelae distribution as to when the treatments were started as we examined 473 patients who were diagnosed with facial palsy, and visited the Out-patient Department of Acupuncture and Moxibustion of Bundang Oriental Medicine Hospital of Dongguk University through 2003 and 2004. Results : The sequelae of facial palsy were not significantly relevant to the signs found before facial palsy occurred(fatigue, stress, chills, and cold), or to patients' past history (hypertension, diabetes mellitus, facial palsy, herpes zoster). The duration of recovery time was within 30 days for 45.3% of the patients examined in this study, and within 90 days for 72.6%. Evaluating the existence of sequelae in relation to age, we found more in the group comprised of patients aged 50 and over than under 50. We found more sequelae in the group which is consisted of patients who had not been treated until 6 days after than within 5 days from the onset. Conclusion: Attention to sequelae will be needed for patients aged 50 and over and who were not treated until 6 days after the onset, as they had more sequelae.

• Nutrition Research and Practice
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• 제8권1호
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• pp.94-102
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• 2014

Diet attrition and failure of long term treatment are very frequent in obese patients. This study aimed to identify pre-treatment variables determining dropout and to customise the characteristics of those most likely to abandon the program before treatment, thus making it possible to modify the therapy to increase compliance. A total of 146 outpatients were consecutively enrolled; 73 patients followed a prescriptive diet while 73 followed a novel brief group Cognitive Behavioural Treatment (CBT) in addition to prescriptive diet. The two interventions lasted for six months. Anthropometric, demographic, psychological parameters and feeding behaviour were assessed, the last two with the Italian instrument VCAO Ansisa; than, a semi-structured interview was performed on motivation to lose weight. To identify the baseline dropout risk factors among these parameters, univariate and multivariate logistic models were used. Comparison of the results in the two different treatments showed a higher attrition rate in CBT group, despite no statistically significant difference between the two treatment arms (P = 0.127). Dropout patients did not differ significantly from those who did not dropout with regards to sex, age, Body Mass Index (BMI), history of cycling, education, work and marriage. Regardless of weight loss, the most important factor that determines the dropout appears to be a high level of stress revealed by General Health Questionnaire-28 items (GHQ-28) score within VCAO test. The identification of hindering factors during the assessment is fundamental to reduce the dropout risk. For subjects at risk, it would be useful to dedicate a stress management program before beginning a dietary restriction.

• Nutrition Research and Practice
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• 제18권2호
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• pp.269-281
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• 2024

BACKGROUND/OBJECTIVES: The objective of this study was to compare dietary habits and mental health among middle school students in urban and rural areas based on bedtime, and to provide evidence supporting appropriate bedtime for Korean middle school students in relation to their healthy dietary habits and mental well-being. SUBJECTS/METHODS: The study population consisted of 25,681 second-year middle school students who participated in the Korea Youth Risk Behavior Survey in 2020-2022. Participants were asked about their bedtime and wake-up time during the past 7 days and were classified into five categories. The study compared the general characteristics, academic factors, dietary habits, and mental health of urban and rural students based on their bedtime. RESULTS: Bedtime was found to be later in the following order: urban female students, rural female students, urban male students, and rural male students. As bedtime got later, the rates of smoking and alcohol consumption increased. Students who went to bed before 11 p.m. had lower academic performance, while rural male students who went to bed after 2 a.m. had lower academic performance. Later bedtime was associated with increased smartphone usage, skipping breakfast, consuming fast food, and drinking carbonated beverages. Later bedtime was also associated with higher perceived stress levels, particularly among students who went to bed after 2 a.m., higher rates of suicidal ideation, experiencing sadness and despair, as well as the prevalence of clinically significant anxiety disorders. CONCLUSION: These results suggest that middle school students who go to bed too late have higher rates of smoking and alcohol drinking, as well as unhealthy eating habits, stress, suicidal ideation, sadness, and anxiety. Therefore, it is necessary to provide educational and social institutional support to promote adequate sleep for the health of adolescents.

• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.2315-2320
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• 2016

Background: This study investigated the influence of religious beliefs on the health of cancer patients and identified the factors contributing to the influence. Materials and Methods: A questionnaire survey was conducted using a convenient sampling method. A structured questionnaire was used to the samplings, and the data of 200 cancer patients were collected. Results: The effects of religion on the health of cancer patients achieved an average score of 3.58. The top five effects are presented as follows: (a) Religion provides me with mental support and strength, (b) religion enables me to gain confidence in health recovery, (c) religion motivates me to cope with disease-related stress positively and optimistically, (d) religion helps me reduce anxiety, and (e) religion gives me courage to face uncertainties regarding disease progression. Moreover, among the demographic variables, gender, type of religion, and experience of religious miracles contributed to the significantly different effects of religion on patients. Specifically, the effect of religion on the health of patients who were female and Christian and had miracle experiences was significantly (p< .01) higher than that on other patients. Conclusions: These results are helpful in understanding the influence of religious beliefs on the health of cancer patients and identified the factors contributing to the influence. The result can serve as a reference for nursing education and clinical nursing practice.

• 구강회복응용과학지
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• 제21권2호
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• pp.183-189
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• 2005

There is no single or simple answer for effective communication between laboratory technician and clinical dentist. Love-hate could be used to describe the relationship between dentists and their labs. Great lab work can make a dentists life much easier and can result in getting many referrals. However, if the lab work is not up to par and/or late, it can add stress and agony to a dentists practice. Also the opposition is right. If the preparations are calibrated, the impressions clear, and the bite registrations accurate, most labs can do their work reasonably well. Unfortunately, many cases received by labs are barely adequate, especially when it comes to reading margins, which are frequently created by the imagination of the person trimming the dies. In other words, both dentists and lab technicians need to be able to understand how each party operates so that solutions to problems can be found. Effective communication with the laboratory is critical if any degree of success is desired.