• KCI Concrete Journal
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• v.12 no.1
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• pp.57-68
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• 2000

The effect of structure size on the nominal strength of unidirectional fiber-polymer composites, failing by propagation of a kink band with fiber microbuckling, is analyzed experimentally and theoretically. Tests of novel geometrically similar carbon-PEEK specimens, with notches slanted so as to lead to a pure kink band (without shear or splitting cracks), are conducted. The specimens are rectangular strips of widths 15.875, 31.75. and 63.5 mm (0.625, 1.25 and 2.5 in and gage lengths 39.7, 79.375 and 158.75 mm (1.563, 3.125 and 6.25 in.). They reveal the existence of a strong (deterministic. non-statistical) size effect. The doubly logarithmic plot of the nominal strength (load divided by size and thickness) versus the characteristic size agrees with the approximate size effect law proposed for quasibrittle failures in 1983 by Bazant This law represents a gradual transition from a horizontal asymptote, representing the case of no size effect (characteristic of plasticity or strength criteria), to an asymptote of slope -1/2 (characteristic of linear elastic fracture mechanics. LEFM) . The size effect law for notched specimens permits easy identification of the fracture energy of the kink bandand the length of the fracture process zone at the front of the band solely from the measurements of maximum loads. Optimum fits of the test results by the size effect law are obtained, and the size effect law parameters are then used to identify the material fracture characteristics, Particularly the fracture energy and the effective length of the fracture process zone. The results suggest that composite size effect must be considered in strengthening existing concrete structural members such as bridge columns and beams using a composite retrofitting technique.

• Journal of Gastric Cancer
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• v.10 no.3
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• pp.91-98
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• 2010

Purpose: Silent mating-type information regulation 2 homologue 1 (SIRT1) is a nicotinamide adenine dinucleotide-dependent deacetylase. SIRT1 plays an important role in the regulation of cell death/survival and stress response in mammals. The aim of this study was to investigate whether the SIRT1 gene is involved in the development or progression of gastric cancers. Materials and Methods: SIRT1 and p53 genes in 86 gastric cancers were examined for genetic alterations by PCR-single strand conformation polymorphism sequencing, as well as SIRT1 protein expression in 170 gastric cancers by immunohistochemistry. Results: In the genetic analysis, we found SIRT1 and p53 mutations in two and 12 cases, respectively. Two missense mutations, c.599 C>T (T200I) and c.1258 G>A (E420K), were detected in the SIRT1 gene coding region. The SIRT1 and p53 mutation were found in mutually exclusive gastric cancers. The immunohistochemistry revealed that SIRT1 overexpression was found in 95 (55.9%) of 170 gastric cancers. Altered SIRT1 expression was not statistically associated with clinicopathological parameters, including tumor differentiation, location, lymph node metastasis, or p53 expression. Two cases with an SIRT1 mutation showed increased SIRT1 expression. Conclusions: These results suggest that genetic alterations and overexpression of the SIRT1 gene may contribute to gastric cancer development.

• Steel and Composite Structures
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• v.8 no.5
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• pp.403-421
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• 2008

The design provisions for semi-rigid steel frames have been incorporated in codes of practice for steel structures. In order to do the same, it is necessary to know the experimental moment-relative rotation (M-${\theta}_r$) behaviour of beam-to-column connections. In spite of numerous publications and collection of several connection databases, there is no unified approach for the semi-rigid design of steel frames. Amongst the many connection models available, the Frye-Morris polynomial model, with its limitations reported in the literature, is simple to adopt at least for the linear design space. However this model requires more number of connection tests and regression analyses to make it a realistic prediction model. In this paper, 3D nonlinear finite element (FE) analysis of beam-column connection specimens, carried out using ABAQUS software, for evaluating the M-${\theta}_r$ behaviour of semi-rigid top and seat-angle (TSA) bolted connections are described. The finite element model is validated against experimental behaviour of the same connection with regard to their moment-rotation behaviour, stress distribution and mode of failure of the connections. The calibrated FE model is used to evaluate the performance of the Frye-Morris polynomial model. The results of the numerical parametric studies carried out using the validated FE model have been used in proposing modifications to the Frye-Morris model for TSA connection in terms of the powers of the size parameters.

• Journal of the Microelectronics and Packaging Society
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• v.9 no.4
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• pp.35-45
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• 2002

The stresses of the underfill/chip interface due to thermal loading was studied using the finite element method. At first, the effective properties of underfill for several volume fractions of silica particles were calculated by Mori-Tanaka method for three different material sets, and the parameters of singularity for the bimaterial edge and the bimaterial wedge were calculated. Consequently, the stresses at the underfill/chip interface with volume fraction of silica particles were investigated. Five different geometric models of flip-chip assembly involving two kinds of bimaterial strips and three kinds of three-layer models were considered under the assumption that the underfill is homogeneous. It was assumed that all components of the flip-chip assembly were linear elastic and isotropic, and their properties were temperature independent. The analysis was conducted in the context of the uncoupled plane thermo-elasticity under a plane strain assumption.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.17 no.1
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• pp.86-93
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• 2003

This paper describes that the resonant tank type DC-DC converter consist of reactor and capacitor resonant tank circuit for increased the output current. This circuit configuration is composed of the resonant tank circuit used resonant capacitor and reactor and the capacitor connected in switch are a common using by resonance capacitor and ZVS(Zero Voltage Switching) capacitor. Therefore, the proposed converter can reduce a switching losses, noise, and voltage stress at turn-on and turn-on and has an advantage which is able to operating safely in load short, because DC reactor is connected with resonance reactor in order to supply a fixed current with low ripple from DC power supply. The analysis of proposed circuit uses normalized parameters and characteristic estimation is generally described the proposed circuit with the characteristics of power and output voltage etc. Also, design is based on the characteristic estmations in each step. Hence, We conform a rightfulness theoretical analysis by comparing a theoretical values and experimental values obtained from experiment.

• Journal of the Korea institute for structural maintenance and inspection
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• v.22 no.6
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• pp.45-52
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• 2018

The paper aimed to find out the lateral behavior of outrigger system in high-rise building considering floor diaphragm. To achieve this goal, a structural schematic design of 80 stories building was conducted by utilizing MIDAS-Gen. In this research, the key parameters of the structure analysis were the outrigger location in plan, the slab stiffness, the outrigger stiffness and the kind of diaphragm. For the purpose of this study, we analyzed and studied the lateral displacement in top floor, the story drift and the stress in slab. The research results indicated that the outrigger location in plan, the slab stiffness, the outrigger stiffness and the kind of diaphragm had an effect on lateral behavior in outrigger system of tall building. And the results of this analysis research can provided the assistance in getting the basic data of structure design for looking for the lateral behavior of outrigger system in the high-rise building.

• Journal of Sensor Science and Technology
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• v.5 no.6
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• pp.15-24
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• 1996

In this study, as a part of the basic study for the application of optical fiber sensors to smart composite structures, the integrity of optical fiber sensors embedded within the composite structures was examined and then the laser signal transmitted through optical fiber sensors during the deformation of host structures was investigated. Firstly, it was found that bending test could be substituted for tensile test by comparing cumulative failure distribution based on weakest link theory and introducing the correction factor. Weibull parameters were obtained through the experiments and the correction factor was found to be applied to cumulative failure distribution derived from bending test. The integrity of embedded optical fiber sensors due to the thermal effect was evaluated by the comparison of the mean tensile strengths of cured and uncured optical fibers. Secondly, relationships between stress-strain curve obtained in tensile test of composite laminate and the intensity of laser signal transmitted through embedded optical fibers were examined and the possibility of the effective damage detection using optical fiber sensors was studied.

• Environmental Analysis Health and Toxicology
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• v.26
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• pp.6.1-6.8
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• 2011

Objectives: The present study investigated the potential adverse effects of multi-wall carbon nanotubes (MWCNTs) on pregnant dams and embryonic development following maternal exposure in rats. Methods: MWCNTs were orally administered to pregnant rats from gestational day (GD) 6 through 19 at dose levels of 0, 8, 40, 200, and 1000 mg/kg/day. During the test period, clinical signs, mortality, body weights, food consumption, serum biochemistry, oxidant-antioxidant status, gross findings, organ weights, and Caesarean section findings were examined. Results: All animals survived to the end of the study. A decrease in thymus weight was observed in the highest dose group. However, maternal body weight, food consumption, serum biochemical parameters, and oxidant-antioxidant balance in the kidneys were not affected by treatment with MWCNTs. No treatment-related differences in gestational index, embryo-fetal mortality, or fetal and placental weights were observed between treated and control groups. Conclusions: The results show that 14-day repeated oral dosing of MWCNTs during pregnancy induces minimal maternal toxicity at 1000 mg/kg/day in rats. Under these experimental conditions, the no-observed-adverse-effect level of MWCNTs is considered to be 200 mg/kg/day for dams and 1000 mg/kg/day for embryonic development.

• Journal of the Korean Society for Marine Environment & Energy
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• v.6 no.2
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• pp.54-62
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• 2003

The free span of a subsea pipeline due to seabed scouring can result in structural failure by severe ocean environmental loads and vortex induced vibrations. This Paper examines the safety of subsea pipelines with free spans under axial compressive load. The variation of allowable lengths of static and dynamic free spans is examined for generalized boundary conditions. The free span is modelled as a beam with an elastic foundations and the boundary condition is replaced by linear and rotational springs at each end. The static and dynamic free span curves are obtained with a function of non-dimensional parameters. A case study is carried out to introduce the application method of the curve. The results of this study can be usefully applied for the design of subsea pipelines with a free span.

• Journal of Dairy Science and Biotechnology
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• v.32 no.2
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• pp.63-70
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• 2014

Automatic milking systems (AMS) have been increasingly introduced to Korean dairy farms. However, in comparison with conventional milking systems (CMS), some negative changes in milk quality are being observed. The use of AMS leads to an increase in milking frequency, which in turn might result in higher physical stress on the milk, possibly causing changes in the milk fat globule (MFG) membrane. Therefore, the purpose of this study was to examine the effect of the different milking systems on the milk quality, with a focus on milk fat properties. At the same time, we studied the effect of feeding the dairy cows with protected fat. Raw milk samples were taken monthly from individual cows as well as from bulk tanks at four AMS and four CMS dairy farms. We measured quality-related parameters such as MFG size distribution, free fatty acid content and composition, and acid values. Although most results showed no significant differences with regard to the milking system, we found a relatively high positive correlation between MFG size and milk fat content. Moreover, larger MFG size was observed in the milk when cows had been fed protected fat. The significantly higher (P< 0.05) free fatty acid content of milk observed under this experimental condition could be attributed to higher milking frequency as a result of using AMS.