Near-infrared spectroscopy (NIRS), a noninvasive optical method, utilizes the characteristic absorption spectra of hemoglobin in the near-infrared range to provide information on cerebral hemodynamic changes in various clinical situations. NIRS monitoring have been used mainly to detect reduced perfusion of the brain during orthostatic stress for three common forms of orthostatic intolerance (OI); orthostatic hypotension, neurally mediated syncope, and postural orthostatic tachycardia syndrome. Autonomic function testing is an important diagnostic test to assess their autonomic nervous systems for patients with symptom of OI. However, these techniques cannot measure dynamic changes in cerebral blood flow. There are many experimentations about study of NIRS to reveal the pathophysiology of patients with OI. Research using NIRS in other neurologic diseases (stroke, epilepsy and migraine) are ongoing. NIRS have been experimentally used in all stages of stroke and may complement the established diagnostic and monitoring tools. NIRS also provide pathophysiological approach during rehabilitation and secondary prevention of stroke. The hemodynamic response to seizure has long been a topic for discussion in association with the neuronal damage resulting from convulsion. One critical issue when unpredictable events are to be detected is how continuous NIRS data are analyzed. Besides, NIRS studies targeting pathophysiological aspects of migraine may contribute to a deeper understanding of mechanisms relating to aura of migraine. NIRS monitoring may play an important role to trend regional hemodynamic distribution of flow in real time and also highlights the pathophysiology and management of not only patients with OI symptoms but also those with various neurologic diseases.
Youngchul Yoo;Mi-jin Chae;Jeong Ju Kim;Seuk Ki Lee;AReum Han;Won Tae Jeon;Dae-Woo Lee;Beom-Young Son
Proceedings of the Korean Society of Crop Science Conference
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2022.10a
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pp.95-95
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2022
Maize is one of the world's three largest crops and has a long cultivation history, and is an important crop used for various purposes such as food, feed, and industrial raw materials. Recently, the agricultural environment is changing, in which the limit of cultivation of crops is shifted to the north due to the rise in temperature due to climate change. This study was conducted in experimental field of Suwon in 2022 by setting a seeding period earlier than the sowing time to establish the North Korean agricultural climatic zone and meteorological conditions. The test cultivars were silage cultivars, Kwangpyeongok and Dacheongok. As a priming test method, it was used to directly plant seeds in the field through immersion using 4mM zinc (Zn) and 2.5mM manganese (Mn), which are trace elements for seeds. The planting season was early on March 15th, April 1st, and April 15th. The number of days from sowing to silk stage of the two cultivars sown on March 15, April 1, and April 15 was 107, 93, and 85 days for Kwangpyeongok and 109, 95, and 87 days for Dacheongok, respectively. The seed priming test did not show any difference from the control group in the growth survey up to the middle stage of growth. In another test, low-temperature recovery was confirmed through nitrogen (2-5%) foliar fertilization after 3 days, 5 days, and 7 days in refrigeration (0 degrees), a selective low temperature treatment for com in the third leaf stage. As a result of this study, it was confirmed that the low-temperature damaged com treated at 0℃ showed the same growth as that of the untreated com through nitrogen foliar fertilization. These results suggest that urea foliar fertilization for low-temperature damage reduction of corn for silage in high-latitude climates will be helpful. In addition, through the results of the study, additional studies are needed on the recovery mechanism and field application through urea foliar fertilization.
Kyung Hye Seo;Hyung Don Kim;Jeong-Yong Park;Dong Hwi Kim;Seung-Eun Lee;Gwi Young Jang;Yun-Jeong Ji;Ji Yeon Lee
Korean Journal of Agricultural Science
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v.49
no.2
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pp.175-184
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2022
The present study investigated the neuroprotective effects of Coreopsis lanceolate extract against hydrogen-peroxide (H2O2)-induced oxidative damage and cell death in pheochromocytoma 12 (PC12) cells. Reactive oxygen species (ROS), 2,2'-azinobis (3-ethylbebzothiazoloine-6-sulfonic acid) diammonium salt, and 1,1-diphenyl-2-picrrylhydrazyl radical scavenging activities, as well as the expression levels of proteins associated with oxidative damage and cell death were investigated. According to the results, C. lanceolate extract exhibited inhibitory activity against intracellular ROS generation and cell-damaging effects induced by hydroxyl radicals in a dose-dependent manner. Total phenolic and flavonoid contents were 22.3 mg·g-1 gallic acid equivalent and 16.2 mg·g-1 catechin equivalent, respectively. Additionally, a high-performance liquid chromatography (HPLC) assay based on the internal standard method used to detect phenolic compounds. The phenolic compounds identified in C. lanceolata extract contained (+)-catechin hydrate (5.0 ± 0.0 mg·g-1), ferulic acid (1.6 ± 0.0 mg·g-1), chlorogenic acid (1.5 ± 0.0 mg·g-1), caffeic acid (1.2 ± 0.0 mg·g-1), naringin (0.9 ± 0.0 mg·g-1), and p-coumaric acid (0.5 ± 0.0 mg·g-1). C. lanceolata extract attenuated pro-apoptotic Bax expression levels and enhanced the expression levels of anti-apoptotic Bcl-2, caspase-3, and caspase-9 proteins. Therefore, C. lanceolata is a potential source of materials with neuroprotective properties against neurodegenerative disorders, such as Alzheimer's and Parkinson's diseases.
Journal of the Korea institute for structural maintenance and inspection
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v.28
no.2
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pp.27-34
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2024
This study was conducted to examine the feasibility of using Fe-activated wood-derived biochar as a conductive filler for manufacturing cement-based strain sensor. To evaluate the compressive and electrical properties of cement composite with 3% Fe-activated biochar, three cubic specimens of size 50 x 50 x 50mm3 and three prismatic cement-based sensors of size 40 x 40 x 80mm3 were prepared respectively. The four-probe method of electrical resistance measurement was used for cement-based sensors. For cement-based sensors with FE-activated biochar, the conductive performance such as electrical resistance and impedance under different water content and repeated compression was investigated. Results showed that the fractional changes in the DC electrical resistivity of cement-based sensors increase with increasing time and the maximum fractional changes in the resistivity decrease with increasing the moisture contents during 900s. At moisture content of 7.5% range, the conductive performance of cement composite including 3% Fe-activated biochar as a conductive filler showed the most stable, while the strain detection ability tended to decrease somewhat as the repeated compressive stress increased between repeated compressive strain and fractional change in resistivity (FCR).
Objective : Children with autism spectrum disorder (ASD) commonly suffer from feeding disorders. Major feeding problems include mealtime behavior problems, picky eating, and a lack of food variety can lead to nutritional problems, developmental and social limitations, and stress for the caregivers. A review of the latest literature was conducted to gain an in-depth understanding of assessment tools for feeding disorders in children with ASD. Method : This study analyzed assessments to identify feeding problems in ASD based on previous studies searched through keywords such as ASD, ASD feeding problem, and ASD feeding evaluation. Results : The ASD feeding disorder assessment was divided into direct and indirect assessments. Indirect assessment, in which caregivers measure a child's situation using questionnaires, is mainly used. The assessment of feeding disorders in children with ASD was divided into 1) mealtime behavior, 2) sensory processing, 3) food consumption, and 4) others. Conclusion : As the main feeding disorder characteristics of children with ASD are very diverse, a comprehensive evaluation is necessary but is still limited. Swallowing rehabilitation experts, such as occupational therapists, should apply comprehensive assessment tools based on a basic understanding of the feeding problems, behaviors, and sensations in ASD.
Journal of Korean Tunnelling and Underground Space Association
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v.25
no.6
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pp.479-493
/
2023
The need for safety management has arisen due to the increasing number of years of operated underground structures, such as tunnels and utility tunnels, and accidents caused by those aging infrastructures. However, in the case of privately managed underground utility ducts, there is a lack of detailed guidelines for facility safety and maintenance, resulting in inadequate safety management. Furthermore, the absence of basic design information and the limited space for safety assessments make applying currently used non-destructive testing methods challenging. Therefore, this study suggests non-destructive inspection methods using ultrasonic and impact-echo techniques to assess the quality of underground structures. Thickness, presence of rebars, depth of rebars, and the presence and depth of internal defects are assessed to provide fundamental data for the safety assessment of box-type general underground structures. To validate the proposed methodology, different conditions of concrete specimens are designed and cured to simulate actual field conditions. Applying ultrasonic and impact signals and collecting data through multi-channel accelerometers determine the thickness of the simulated specimens, the depth of embedded rebar, and the extent of defects. The predicted results are well agreed upon compared with actual measurements. The proposed methodology is expected to contribute to developing safety diagnostic methods applicable to general underground structures in practical field conditions.
Purpose: In this paper, an experimental study was conducted to analyze the difference in shear strength caused by the problem of excluding coarse particles due to the size of the test specimen in the direct shear test. Method: A large-scale direct shear test was conducted on three weathered soils containing coarse aggregates with a maximum diameter of 50mm. In addition, a small-scale direct shear test was performed using a sample with a maximum diameter of 5 mm, excluding coarse aggregates. Result: In the case of the small-scale direct shear test, compared to the results of the large-scale direct shear test containing large particles, the internal friction angle was about 2.3% smaller, and there was no significant difference. In terms of cohesion, compared to the large-scale direct shear test, the small-scale direct shear test derived about 80.3% smaller value, showing a relatively large difference. Conclusion: In the large-scale direct shear test, it was analyzed that the coarse particles had a greater impact on the cohesion than the internal friction angle. Therefore, granite weathered clay containing coarse particles is judged to have the same shear strength as the cohesive force that is not affected by vertical stress. In this study, it was analyzed that the small-scale direct shear test, which excludes the coarse particles that are commonly used, provides results on the safety side by excluding the effect of coarse particles.
Analyzing the collapse behavior of thin-walled steel structures holds significant importance in ensuring their safety and longevity. Geometric imperfections present on the surface of metal materials can diminish both the durability and mechanical integrity of steel shells. These imperfections, encompassing local geometric irregularities and deformations such as holes, cavities, notches, and cracks localized in specific regions of the shell surface, play a pivotal role in the assessment. They can induce stress concentration within the structure, thereby influencing its susceptibility to buckling. The intricate relationship between the buckling behavior of these structures and such imperfections is multifaceted, contingent upon a variety of factors. The buckling analysis of thin-walled steel shell structures, similar to other steel structures, commonly involves the determination of crucial material properties, including elastic modulus, shear modulus, tensile strength, and fracture toughness. An established method involves the emulation of distributed geometric imperfections, utilizing real test specimen data as a basis. This approach allows for the accurate representation and assessment of the diversity and distribution of imperfections encountered in real-world scenarios. Utilizing defect data obtained from actual test samples enhances the model's realism and applicability. The sizes and configurations of these defects are employed as inputs in the modeling process, aiding in the prediction of structural behavior. It's worth noting that there is a dearth of experimental studies addressing the influence of geometric defects on the buckling behavior of cylindrical steel shells. In this particular study, samples featuring geometric imperfections were subjected to experimental buckling tests. These same samples were also modeled using Finite Element Analysis (FEM), with results corroborating the experimental findings. Furthermore, the initial geometrical imperfections were measured using digital image correlation (DIC) techniques. In this way, the response of the test specimens can be estimated accurately by applying the initial imperfections to FE models. After validation of the test results with FEA, a numerical parametric study was conducted to develop more generalized design recommendations for the stainless-steel shell structures with the initial geometric imperfection. While the load-carrying capacity of samples with perfect surfaces was up to 140 kN, the load-carrying capacity of samples with 4 mm defects was around 130 kN. Likewise, while the load carrying capacity of samples with 10 mm defects was around 125 kN, the load carrying capacity of samples with 14 mm defects was measured around 120 kN.
To reduce both the floatation of the seedling of rice and the failure in standing in the paddy field when the barley straw was applied to paddy field before planting the rice, we tested the effect of rice rooting with plowing methods and irrigation rates for 2 years from 2003 to 2004. This study was carried out in paddy field with Fluvio-Marine deposit in Jeonbug series and the operating accuracy and the change of soil physico-chemical properties depending on plowing methods and irrigation rates following the barley straw applying were examined. There was a less floatation of barley straw in the dry-rotaryI+water-rotaryI(DRI+WRI) plot than in the plowing+water-rotary(PL+WRI) plot. The ratio of miss-planted and floating seedling also decreased by 1.7%, 2.6% in the DRI+WRIplot compared with PL+WRI plot. The soil physical property was improved with the decreasing soil hardness, bulk density and increasing soil porosity after the application of barley straw, especially enhanced greatly in the increase of porosity, gaseous phase and with the decrease of soil hardness, bulk density of subsurface soil in DRI+WRI plot. And the change of soil chemical property were increased the content of total carbon$^{\circ}{\S}$nitrogen$^{\circ}{\S}$organic matter and available phosphate while decreased the content of exchangeable cations and available silicate after the application of barley straw. Also the content of organic matter, available phosphate and cation exchangeable capacity were increased, whereas caron/nitrogen ratio was decreased in DRI+WRI plot compared with PL+WRI plot. The number of panicles, spikelets per square meter were increased and 1,000 grains weight of hulled rice was gained more in DRI+WRI plot at irrigation rate of $500ton\;ha^{-1}$, in DRI+WRII plot at irrigation rate of $700ton\;ha^{-1}$. So the rice yields were increased by 7%, in DRI+WRI and 5% in DRI+WRII plot, respectively compared with PL+WRI plot. The result of this study indicated that the most appropriate plowing method with barley straw application on rice cultivation at double cropping in normal paddy field plain land was DRI+WRI.
Kim Boong-Nyun;Jung Kwang-Mo;Cho Soo Churl;Hong Kang-E
Journal of the Korean Academy of Child and Adolescent Psychiatry
/
v.16
no.1
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pp.79-89
/
2005
Objectives : To acquire an improved understanding of oppositional defiant disorder, we evaluated the characteristics of children who have the symptoms of ODD in community sample. Methods : 1200 children from an elementary school in Bucheon (an urban community near Seoul) were recruited by randomized sampling method. By Disruptive Behavior Disorder Scale according to DSM-III-R & DSM-IV, we evaluated the symptoms of ODD and selected subjects with ODD. Psychiatric comorbidity, character trait were compared in subjects with ODD and comparison group. Also we examined the association between prenatal/perinatal risk factors, family functions and the symptoms of ODD. Data were analyzed by appropriate statistical method using SPSS 11.5 window version. Result : Children with oppositional defiant disorder were revealed to have significantly higher rates of psychiatric comorbidity and significantly greater family dysfunction compared to comparison group. Among the prenatal/perinatal risk factors, severe emotional stress during pregnancy, postpartum depression, medication during pregnancy were revealed as risk factors of ODD. In character inventory, ODD group were evaluated to have high score in novelty seeking, harm avoidance, but low in reward dependency. Conclusion : These results support that 1) prenatal/perinatal and psycho-social risk factors could be a important role in the progression of ODD, and 2) children with ODD have diverse comorbid psychiatric symptoms.
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