• Structural Engineering and Mechanics
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• 제74권3호
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• pp.445-455
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• 2020

Shear lag phenomenon has long been taken into consideration in various structural codes; however, the AISC provisions have not proposed any specific equation to calculate the shear lag ratio in some cases such as fillet-welded connections of front-to-front double channel sections. Moreover, those equations and formulas proposed by structural codes are based on the studies that were conducted on riveted and bolted connections, and can be applied to single channel sections whilst using them for fillet-welded double channels would be extremely conservative due to the symmetrical shape and the fact that bending moments will not develop in the gusset plate, resulting in less stress concentration. Numerical models are used in the present study to focus on parametric investigation of the shear lag effect on fillet-welded tension connection of double channel section to a gusset plate. The connection length, the eccentricity of axial load, the free length and the thickness of gusset plate are considered as the key factors in this study. The results are then compared to the estimates driven from the AISC-LRFD provisions and alternative equations are proposed.

• 한국동물생명공학회지
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• 제36권1호
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• pp.2-8
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• 2021

Dimethachlor is a synthetic herbicide, belonging to the chloroacetanilide group, that inhibits the undesirable growth of weeds via the suppression of very long-chain fatty acid synthesis. Although dimethachlor has been shown to run off from agricultural fields into aquatic ecosystems, the toxicity of dimethachlor on aquatic invertebrates and vertebrates is unknown. In our study, we assessed the toxicity of dimethachlor on developing zebrafish embryos by analyzing viability, hatching ability, and phenotypic changes. Embryonic viability decreased from 48 h post-fertilization (hpf) at the highest concentration of dimethachlor. Decreased hatching ratio, shortened body length, and pathological changes in the eye, heart, and yolk sac were observed at sub-lethal concentrations. Additionally, dimethachlor increased the number of apoptotic cells and level of reactive oxygen species 120 hpf. Our results indicate that dimethachlor may act as an anti-developmental toxicant when accumulated in an aquatic environment.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2003년도 Annual Meeting of KSAP : International Symposium on Pharmaceutical and Biomedical Sciences on Obesity
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• pp.79-79
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• 2003

Recently diabetes has been found to be associated with metabolic bone diseases such as osteoporosis. In the present study, attempts have been made-to explore the effect of high glucose in bone formation. Osteoblast-like UMR 106 cells were treated with high glucose (22mM, 33mM, 44mM) for 1 or 2 days. High glucose significantly inhibited proliferation of UMR106 cells in a time- and dose- dependent manner as evidenced by MTT assay. For the evaluation of collagen synthesis, UMR 106 cells were cultured in high glucose media (44mM) for 24 h and the ratio of collagen content to total protein was measured. In addition, gene expression pattern of type I collagen was assessed by RT-PCR. The high concentration of glucose inhibited a collagen synthesis, a marker of bone formation activity. JNK, c- Jun N-terminal Kinase, is known to play an important role in stress-associated cell death. In this regard, we tested to determine whether high glucose has any effect on JNK activity. It has been found that treatment of high glucose induced phosphorylation of JNK. On the other hand, ERK phosphorylation was inhibited by high glucose in a dose-dependent manner. Taken together, Therefore these results indicate that inhibition of proliferation in UMR 106 cells following high glucose is related to JNK/ERK containing signal pathways. This study showed high glucose concentration could alter the bone metabolism leading to defective bone formation, suggesting that high glucose due to diabetes may playa significant role in the development of metabolic bone disease.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.189-189
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• 2017

Salinity is one of the major abiotic stresses that severely affect crop production throughout the world; especially rice plant which is generally categorized as a typical glycophyte as it cannot grow in the presence of salinity. Phenotypic resistance of salinity is expressed as the ability to survive and grow in a salinity condition. Salinity resistance has, at least implicitly, been treated as a single trait. Physiological studies of rice suggest that a range of characteristics (such as low shoot sodium concentration, compartmentation of salt in older rather than younger leaves, high potassium concentration, high $K^+/Na^+$ ratio, high biomass and plant vigour) would increase the ability of the plant to cope with salinity. Criteria for evaluating and screening salinity tolerance in crop plants vary depending on the level and duration of salt stress and the plant developmental stage. Plant growth responses to salinity vary with plant life cycle; critical stages sensitive to salinity are germination, seedling establishment and flowering. We have established a standard protocol to evaluate large rice germplasms for overall performance based on specific physiological traits for salt tolerance at seedling stage. This protocol will help in identifying germplasms which can perform better in the presence of different salinity treatments based on single trait and also combination of different physiological traits. The salt tolerant germplasm can be taken forward into developing better varieties by conventional breeding and exploring genes for salt tolerance.

• 대한지역사회영양학회지
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• 제5권3호
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• pp.432-443
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• 2000

Smoking can increase oxidative stress and thereby change the antioxidant defense system in the body. Supplementation of antioxidant vitamins might improve antioxidant status in the body. The purpose of this study was to evaluate the effectiveness of vitamin C supplementation and smoking cessation education on changes of antioxidant status and psychosocial factors related to smoking. To obtain above purposes, we investigated the effectiveness of intervention for male adolescent smokers were evalnate by assessing changes in dietary intakes, plasma antioxidant vitamin concentration, and psychosocial factors related to smoking after program completion. Subjects, male adolescent smokers, were assigned into four groups : Control group(19 students), Educ. group(19 students), Vit. C supple. group(19 students), and Educ.+Vit. C suppl. group(19 students). The Educ. group and Educ.+Vit. C suppl. group received nutrition and smoking cessation education once a week for 5 weeks. Vit. C suppl. group and Educ.+Vit. C suppl. group received 500 mg per day of ascorbic acid for 35 days. All data were collected before and after intervention. Vit. B$_2$and Vit. C intakes of all groups were increased, but the only Ca intake was increased in the Educ. group. Plasma Vit. C concentration and Ratio(plasma Vit. C/Vit. C intakes) were increased in the Vit. C suppl. group and Educ.+Vit. C suppl. group, and the Vit. C deficiency status of these groups(Vit. C suppl. group and Educ.+Vit. C suppl. group) disappeared. Showing the effects of Vit. C supplementation, plasma $\alpha$-tocopherol was increased in the Educ. and Educ.+Vit. C suppl. group, and especially high increases were seen in the Educ.+Vit. C suppl. group. Psychosocial factors related to smoking changed after the education a little. This intervention program had an impact on nutrition intakes, plasma antioxidant vitamins, and some beliefs related to smoking in male adolescent students. Various programs of nutrition and smoking cessation education and vitamin supplementation for quitting smoking must be implemented for adolescent smokers, and further studies are needed regarding sorts and amount of antioxidant nutrients and supplementation periods.

• 한국수산과학회지
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• 제51권6호
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• pp.688-696
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• 2018

This study investigated the effects of ozone-produced oxidants (OPO) on the growth, hematology, and histology of olive flounder Paralichthys olivaceus (average weight 500 g), raised in an ozonated semi-recirculating aquaculture system. The system was ozonated to maintained OPO concentrations of 0.004 (Control), 0.014 (OPO15), and 0.025 (OPO25) mg $Cl_2/L$ in culture tanksfor 26 days. The specific growth rate, feed conversion ratio, and survival rate did not significantly differ among the groups (P>0.05), while the daily feeding rate decreased OPO-dose-dependently (P<0.05). OPO appeared to affect the gill, hepatopancreas, and kidney tissues of fish from ozonated tanks. Hematologically, OPO affected some blood indices. The levels of chloride, glucose, glutamic oxaloacetic transaminase, and glutamic pyruvic transaminase were significantly increased in the ozonated groups, while the total cholesterol and cortisol decreased dose-dependently. These results imply that long-term exposure of olive flounder to an OPO concentration ${\geq}0.014mg\;Cl_2/L$ might result in damage to the gill, hepatopancreas, and kidney tissues and cause physiological stress, albeit with no apparent short-term effects on growth or survival.

• Structural Engineering and Mechanics
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• 제73권6호
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• pp.613-620
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• 2020

The research study is focuses on a form of all-bolted joint with the external ring stiffening plate in the prefabricated steel structure. The components are bolted at site after being fabricated in the factory. Six specimens were tested under cyclic loading, and the effects of column axial compression ratio, concrete-filled column, beam flange sub plate, beam web angle cleats, and spliced column on the failure mode, hysteretic behavior and ductility of the joints were analyzed. The results shown that the proposed all-bolted joint with external ring stiffening plate performed high bearing capability, stable inflexibility degradation, high ductility and plump hysteretic curve. The primary failure modes were bucking at beam end, cracking at the variable section of the external ring stiffening plate, and finally welds fracturing between external ring stiffening plate and column wall. The bearing capability of the joints reduced with the axial compression ratio increased. The use of concrete-filled steel tube column can increase the bearing capability of joints. The existence of the beam flange sub plate, and beam web angle cleat improves the energy dissipation, ductility, bearing capacity and original rigidity of the joint, but also increase the stress concentration at the variable section of the external reinforcing ring plate. The proposed joints with spliced column also performed desirable integrity, large bearing capacity, initial stiffness and energy dissipation capacity for engineering application by reasonable design.

• Composites Research
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• 제14권1호
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• pp.1-7
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• 2001

본 연구에서는 유리 섬유 강화 열가소성 복합재료의 손상평가를 음향방출법을 이용하여 관찰하였다. 시편은 PET와 유리섬유를 7겹으로 적층시켜 만들었으며 두께는 1.7mm이다. 노치 시험편과 풍격 시험편을 제작하여 단순인장 시험과 부하-제하 시험을 수행하였다. AE 신호의 파라미터와 파괴모드간의 관계를 찾아내기 위해 충격 에너지와 노치비의 함수로 AE신호를 측정하였다. 실험견과 모재의 미소균열과 성장 때문에 저진폭 AE 신호가 나타났고, 중진폭 신호는 섬유와 모재간의 층간분리와 계면분리에 대응됐다. 또한 90dB의 고진폭 영역에서는 유리섬유의 파단과 대응되었다 층간분리와 모재의 균열과 음력집중의 영향 때문에 노치비와 충격 에너지가 증가할수록 인장강도는 감소했다. 손상영역의 비율에 따라 AE 신호는 넓은 영역의 주파수가 나타날 뿐만 아니라 신호도 증가하였다.

• 혜화의학회지
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• 제12권1호
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• pp.129-137
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• 2003

Clinical studies were carried out 29 cases through administration of Sanjointang added Grape Juice(ST+GJ) from December 1st 2002 to December 30th 2002. The results were summarized as follows; 1. There were significant decreases in physical symptoms of fatigue from $4.34{\pm}2.70$ to $2.34{\pm}1.78$ by administration of ST+GJ. 2. There were significant decreases in mental symptoms of fatigue from $5.10{\pm}2.74$ to $3.76{\pm}2.23$ by administration of ST+GJ. 3. There were significant decreases in neuro-sensory symptoms of fatigue from $3.66{\pm}2.13$ to $2.69{\pm}2.07$ by administration of ST+GJ. 4. There were significant decreases in total subjective symptoms of fatigue from $13.14{\pm}6.18$ to $8.79{\pm}4.63$ by administration of ST+GJ. 5. There were significant decreases in VAS of fatigue ratio, but not significant changes in VAS of concentration ratio by administration of ST+GJ. According to the results, we could suggest that ST+Gj is able to be applied to the relaxion of stress.

• 한국주조공학회지
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• 제38권6호
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• pp.121-131
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• 2018

The effect of additives on the castability of the AC2BS aluminum alloy, which contains 35% recycled scrap, was investigated. For the wide utilization of the recycled scrap AC2BS aluminum alloy, the research results were compared to those with the AC2B virgin alloy, which is typical Al-Si-Cu alloy system. It was confirmed that the addition of Al-5%Ti-1%B increased the ${\alpha}$-Al nucleation temperature during solidification and decreased the grain size through cooling curve and microstructural observations of the recycled alloy. It was also found that an addition of Al-10%Sr decreased the eutectic Si growth temperature during the solidification process and modified the shape of the eutectic Si of the recycled alloy. The characteristics of fluidity, shrinkage and solidification crack strength were evaluated. For the AC2BS aluminum alloy containing 35% recycled scrap, both ${\alpha}$-Al grain refinement due to Ti-B and eutectic Si modifications due to Sr contributed to the improvement of the fluidity. The macro- shrinkage ratio increased with additions of both Al-10%Sr and Al-5%Ti-1%B and the micro-shrinkage ratio increased with the addition of Al-10%Sr but decreased with the addition of Al-5%Ti-1%B. The casting characteristics of TiB and Sr-treated AC2BS aluminum alloy containing 35% recycled scrap are similar to those of AC2B virgin alloy. The improvement of the solidification crack strength of the AC2BS aluminum alloy was possible by the reduction of the grain boundary the stress concentration through the enhancement by both ${\bullet}{\cdot}$-Al refinement and eutectic Si modification. More extensive use of the AC2BS aluminum alloy containing 35% recycled scrap can be expected in the future.