• Korean Journal of Fisheries and Aquatic Sciences
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• v.39 no.4
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• pp.333-337
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• 2006

The anti-inflammatory activities of marine actinomycetes were surveyed. In total, 363 strains were isolated from marine sediments, seaweed tissue, and seaweed rhizosphere. Of these, strains 16 and 291-11 showed the most potent anti-inflammatory activity in phorbol-ester-induced mouse ear edema and erythema assays. Strains 16 and 291-11 were isolated from the rhizosphere of the brown seaweeds Sargassum thunbergli and Undaria pinnatifida, respectively, and were identified as Streptomyces macrosporeus and St. praecox, respectively, using 165 rDNA sequence analysis.