• Journal of the Society of Cosmetic Scientists of Korea
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• v.48 no.2
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• pp.169-180
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• 2022

Streptococcus sp. is generally known as a strain that produces hyaluronic acid. In this study, we focused on ingredients other than hyaluronic acid among several metabolites produced by Streptococcus sp. during cultivation. The hair experimental sample (HAIRCLE^TM) was prepared with Streptococcus sp. culture filtrate under the condition that hyaluronic acid was not produced and the effect on the hair was identified. Tensile strength of hair was tested with a universal testing machine (UTM). Surface properties of a hair were examined with an atomic force microscope (AFM). Our results suggest that HAIRCLE^TM could prevent damage to a hair such as destroyed-cuticle, increased-faction force, and broken-hair. Furthermore, hair-related experiments confirmed that HAIRCLE^TM could promote the expression of hair growth factors VEGF, HGF, and Wnt10b and mitigate male hair loss by inhibiting androgen receptors and TGF-β2 expression. In addition, it was confirmed that the expression of barrier-related factors (INV, CLDN-1) was increased for oxidative stress, and the COX-2 expression, an inflammatory factor, was inhibited, thereby improving damaged scalp barriers and alleviating induced inflammation.

• Journal of Aquaculture
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• v.10 no.1
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• pp.9-15
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• 1997

The pathogenic organisms occurred in cultured marine fishes in Kamak Bay were investigated from March to November in 1993. The samples were collected at 7 sampling stations once a month. Nine species of pathogenic organisms (Vibrio sp., Edwardsiella sp., Flexibacter sp., Streptococcus sp., Micrococcus sp., Caligus sp., Trichodina sp., Lymphocystis and Staphylococcus sp.) were identified as pathogenic organisms from four different species of fish (Sebastes schlegeli, Paralichthys olivaceus, lateolabrax japonicus and Pagrus major) collected in the study areas. Most of pathogenic organisms were found at over 20^{\circ}C$ of sea water temperature from June to October in 1993. On the test of drug sensitivity, Vibrio sp. (KS-9303) was sensitive to oxytetracycline and chloramphenicol ; Edwardsiella sp. (KP-9315) to oxytetracycline ; Flexibacter sp. (KP-9318) to oxytetracycline, chloramphenicol and oxolinic acid ; Streptococcus sp. (KP-9319) to erythromycin, chlorampheicol and oxytetracycline. However, all these 4 isolated bacteria were resistant to ampicilin, steptomycin, sulfamethoxazole and nitrofurazone.

• Journal of Oral Medicine and Pain
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• v.22 no.1
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• pp.15-22
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• 1997

In order to investigate the antibacterial effects of pulsed Nd:YAG Laser concerning to Streptococcus mutans, Streptococcus mutans was cultured and standardized and plated in 96 well plates. After that, black dye and chlorhexidine were applied and pulsed Nd:YAG Laser was irradiated to plates. Experimental groups which was applied with black dye and chlorhexidine were divided into 5 groups by concentration. And experimental groups and control group were subdivided as unlased and lased of 20, 40, and 60J. After laser irradiation, All groups were plated in agar plates and incubated for 18 hours. Bacterial colonies were counted and analysed comparitively, and the temperature of culture medium was measured on every laser irradiation. The results were obtained as follows; 1. In case of laser irradiation only, there is no significant reduction in number of Streptococcus mutans by irradiated energy of laser. 2. In case of black dye application, there is no difference by concentration of black dye but there is decrease when applied Laser and black dye simultaneously. 3. When applied chlorhexidine, the number of Streptococcus mutans was decreased according to increase of concentration, but there is no difference by irradiated energy of laser. 4. The temperature of culture medium was increased according to increase of irradiated energy of Laser, and the number of Streptococcus mutans was reduced remarkably just above 50 centigrade and killed above 70 centigrade. As above results, pulsed Nd:YAG Laser has well-absorbing affinity to black dye. And antibacterial effect of pulsed Nd:YAG Laser against Streptococcus mutans is seemed to be due to increase of temperature.

• The Korean Journal of Food And Nutrition
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• v.12 no.2
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• pp.199-203
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• 1999

To evaluate antidental caries activity of polylysine cell growth and acid production of Streptococcus mutans and lactobacillus acidophilus were microbiologically monitored in anaerobic broth system containing various concentration of polylysine. The pH and heat stability of polylysine having antimicrobial activity were also examined. Two tested microbes were fairly well grown in broth containing polylysine 0.1mg/ml however inhibited at 1 and 2mg/ml of polylysine concentration. Especially lag times of Strep-tococcus mutans and Lactobacillus acidophilus were prolonged to about hour at 1.0 and 2.0 mg/ml of poly-lysine. acid production of Streptococcus mutans and lactobacillus acidophilus was also decreased by poly-lysine. Antimicrobial activity of polylysine was not affected by the change of pH and the heat treat-ment.

• Korean Journal of Microbiology
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• v.30 no.3
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• pp.213-217
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• 1992

Glucosyltransferase of Streptococcus mutans NCTC 10449 was purified and characterized. It relates with production of insoluble glucan in dental caries. The molecular weight was estimated to be 152.000. The optimum pH and temperature was 6.5 and $35^{\circ}C$. respectively. The enzyme was stable in alkaline pH. The Michaelis constants of the enzyme for releasing of fructose were 48 mM. Hydrolysis rate of insolut~le glucan by tlextranase was higher in S. mutuns NCTC 10449 than that of strains isolated from saliva.

• YAKHAK HOEJI
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• v.34 no.6
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• pp.434-438
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• 1990

The methanolic extract of the root-bark of Morus alba L.(Mulberry tree) has the potent antibacterial activity against Streptococcus mutans. Its active component was identified to be sanggenon C. The active component had stronger anti-bacterial activity than berberine, having minimum inhibitory concentration(MIC) of $25\;{\mu}g/ml$. Moreover, the inhibitory effect of this component on the cellular adherence of Streptococcus mutans to glass surfaces also was more remarkable than that of berberine in the presence of glucosyltransferase(GTase) and sucrose in vitro. These results indicate that sanggenon C may play an important role in inhibiting plaque formation and caries incidence.

• The Journal of Korean Academy of Prosthodontics
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• v.39 no.4
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• pp.444-451
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• 2001

The purpose of this study was to evaluate the rate of adherence of bacteria on various denture relining materials and to find out the effects of chitosan, when it was added to denture relining materials. Denture relining materials such as Tokuso rebase normal $set^{(R)}$, Mild $rebaron^{(R)}$, $Kooliner^{TM}$, and New $truliner^{TM}$ were used in this study. The adherence of Streptococcus mutans was studied on the surfaces in the denture relining materials with chitosan and in those without chitosan. When chitosan was added to M17 broth and MRS broth, the viable cell count of Streptococcus mutans was reduced. The viable cell count of Streptococcus mutans on the specimens decreased in the following order : Mild rebaron, Tokuso rebase normal set, and Newtruliner and Kooliner. The deture relining materials with chitosan showed a lower rate of adherence of Streptococcus mutans than those without chitosan.

• Microbiology and Biotechnology Letters
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• v.19 no.5
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• pp.429-432
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• 1991

In order to prepare probiotics, a strain which has resistant against acid, bile salts and antibiotics was isolated from infant and anirnat feces. Among these isolated strains, TK- 19 showed a strong acid tolerance and growth at 500 $\mu g$/ml of Na-deoxycholate. Also strain TK-19 was resistant to kanarnycin (30 $\mu g$/ml), streptomycin (10 $\mu g$/ml), nisin (50 $\mu g$/ml) and tetracycline (10 $\mu g$/ml). The isolated strain TK-19 was identified as Streptococcus faeciam, and was named Streptococcus faeciurn TK-19.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2011.10a
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• pp.934-937
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• 2011

As part of our screening of anticariogenic agents from medicinal plants, the ethanol extracts of 10 herbs widely used in the fork medicine were tested for the antimicrobial activity against a cariogenic bacterium Streptococcus sobrinus. The ethanol extracts of Dryopteris crassirhizoma showed antimicrobial activities against S. sobrinus. These results suggested that the extracts of Dryopteris crassirhizoma could be the potential source of antimicrobial agent against S. sobrinus.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.6
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• pp.1625-1628
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• 2006

The (-)-pimara-9 (11), 15-dien-19-oic acid, acanthoic acid was extracted from the roots of Acanthopanax koreanum using bioassay-guided isolation of a MeOH extract. Acanthoic acid was assayed against Streptococcus mutans and Staphylococcus epidermidis causing dental caries and opportunistic pathogen. The minimum inhibitory concentration (MIC) of acanthoic acid against Streptococcus mutans and Staphylococcus epidermidis was 2 and 4 ${\mu}g/mL$, respectively, which was much lower than those of other natural antimicrobial agents such as 8 ${\mu}g/mL$ of tanshinone IIA. Acanthoic acid also significantly inhibited the growth of other cariogenic bacteria such as Streptococcus sobrinus and Streptococcus sanguis, and Streptococcus grodenii in the MIC range of 4${\sim}$32 ${\mu}g/mL$. Our findings suggest that acanthoic acid could be employed as a potential antibacterial agent for preventing dental caries and skin infections.