• Title/Summary/Keyword: Stratified Hazard Model

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Study on Theoretical Models of Regional Humanity Lung Cancer Hazards Assessment

  • Zhang, Chuan;Gao, Xing
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.5
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    • pp.1759-1764
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    • 2015
  • Purpose: To establish the concept of lung cancer hazard assessment theoretical models, evaluating the degree of lung cancer risk of Beijing for regional population lung cancer hazard assessment to provide a basis for technical support. Materials and Methods: ISO standards were used to classify stratified analysis for the entire population, life cycle, processes and socioeconomic management. Associated risk factors were evaluated as lung cancer hazard risk assessment first class indicators. Study design: Using the above materials, indicators were given the weight coefficients, building lung cancer risk assessment theoretical models. Regional data for Beijing were entered into the theoretical model to calculate the parameters of each indicator and evaluate the degree of local lung cancer risk. Results: Adopting the concept of lung cancer hazard assessment and theoretical models for regional populations, we established a lung cancer hazard risk assessment system, including 2 first indicators, 8 secondary indicators and 18 third indicators. All indicators were given weight coefficients and used as information sources. Score of hazard for lung cancer was 84.4 in Beijing. Conclusions: Comprehensively and systematically building a lung cancer risk assessment theoretical model for regional populations in conceivable, evaluating the degree of lung cancer risk of Beijing, providing technical support and scientific basis for interventions for prevention.

Spatial Impacts of Brownfield Redevelopments on Neighborhood Housing Turnover and Stability - Case Study of Cuyahoga County, Ohio in the US - (브라운필드 재개발이 주변 지역 주택소유회전 및 주거 안정성에 미치는 공간적 파급효과 - 미국 오하이오주 쿠야호가 카운티를 중심으로 -)

  • Woo, Ayoung
    • Journal of KIBIM
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    • v.10 no.3
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    • pp.54-62
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    • 2020
  • There is growing consensus among planners and policymakers that brownfield remediation has positive impacts on neighborhoods in terms of housing prices, public health, and environmental quality. However, there is a limited understanding of how brownfield redevelopments spatially affect neighborhood housing turnover and stability. This paper addresses the spatial impacts of brownfield redevelopments on neighboring housing turnover in Cuyahoga County, Ohio. This study examines housing turnover before and after the remediation of brownfield sites countywide and in housing submarkets stratified by household income. Based on housing sales data between 1996 and 2007, the extended Cox Hazard model with the difference-in-difference approach is employed to clarify the causal relationships between brownfield redevelopments and neighboring housing turnover. Additionally, along with the results of the previous study examining impacts of brownfield remediation on nearby housing prices, this paper estimates the change of neighborhood stability due to brownfield redevelopments based on both attributes of housing prices and turnovers.

Analysis of Nested Case-Control Study Designs: Revisiting the Inverse Probability Weighting Method

  • Kim, Ryung S.
    • Communications for Statistical Applications and Methods
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    • v.20 no.6
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    • pp.455-466
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    • 2013
  • In nested case-control studies, the most common way to make inference under a proportional hazards model is the conditional logistic approach of Thomas (1977). Inclusion probability methods are more efficient than the conditional logistic approach of Thomas; however, the epidemiology research community has not accepted the methods as a replacement of the Thomas' method. This paper promotes the inverse probability weighting method originally proposed by Samuelsen (1997) in combination with an approximate jackknife standard error that can be easily computed using existing software. Simulation studies demonstrate that this approach yields valid type 1 errors and greater powers than the conditional logistic approach in nested case-control designs across various sample sizes and magnitudes of the hazard ratios. A generalization of the method is also made to incorporate additional matching and the stratified Cox model. The proposed method is illustrated with data from a cohort of children with Wilm's tumor to study the association between histological signatures and relapses.

Timing and Risk Factors of Adoption for Legally-Free Foster Children after Having Parental Rights Terminated in the U. S. (미국 위탁아동의 친권상실선고 이후 입양 결정요인에 관한 생존분석)

  • Song, Min-Kyoung
    • Korean Journal of Social Welfare
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    • v.59 no.1
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    • pp.301-327
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    • 2007
  • The purpose of this study is to examine the timing and the risk factors associated with the adoption of legally-free foster children. The sample of the study was drawn from foster care files of Adoption and Foster Care Analysis and Reporting System(AFCARS) in 32 states between October 1998 (FY 1999) and September 2002(FY 2002). The timing post-TPR to adoption was examined by plotting the Kaplan-Meier cumulative hazard function for adoption and by plotting the KM hazard functions stratified by child's race and child's age at TPR. Cox proportional-hazards regression analysis was used to identify risk factors for adoption of legally-free foster children after TPR. The hazard of adoption was very low immediately after TPR but increased steadily starting at 3 months and then declined after 20 months. The cumulative hazard functions for White non-Hispanic children and Black non-Hispanic children crossed over at 13 months after TPR. Racial minority status, older age, and disability were negatively associated with the hazard of adoption. Physical abuse, sexual abuse had the lower hazard for adoption compared by neglect. Caretaker's inability to cope had the slightly lower hazard for adoption whereas inadequate housing showed the slightly greater hazard for adoption. Characteristics of foster care services turned into be powerful predictors of adoption. Specifically, legally-free children placed in pre-adoptive homes, those who shared the same racial/ethnic background with their foster caretakers, and those who were placed in two-parent families have a greater likelihood of adoption. The findings highlight the importance of foster care service provisions after TPR to facilitate adoption of legally-free foster children. Furthermore, a more substantial resources and targeted support for foster children who experience physical abuse and sexual abuse in need of adoption should be provided for moving the foster children into permanency.

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Low Systolic Blood Pressure and Mortality From All Causes and Vascular Diseases Among Older Middle-aged Men: Korean Veterans Health Study

  • Yi, Sang-Wook;Ohrr, Heechoul
    • Journal of Preventive Medicine and Public Health
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    • v.48 no.2
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    • pp.105-110
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    • 2015
  • Objectives: Recently, low systolic blood pressure (SBP) was found to be associated with an increased risk of death from vascular diseases in a rural elderly population in Korea. However, evidence on the association between low SBP and vascular diseases is scarce. The aim of this study was to prospectively examine the association between low SBP and mortality from all causes and vascular diseases in older middle-aged Korean men. Methods: From 2004 to 2010, 94 085 Korean Vietnam War veterans were followed-up for deaths. The adjusted hazard ratios (aHR) were calculated using the Cox proportional hazard model. A stratified analysis was conducted by age at enrollment. SBP was self-reported by a postal survey in 2004. Results: Among the participants aged 60 and older, the lowest SBP (<90 mmHg) category had an elevated aHR for mortality from all causes (aHR, 1.9; 95% confidence interval [CI], 1.2 to 3.1) and vascular diseases (International Classification of Disease, 10th revision, I00-I99; aHR, 3.2; 95% CI, 1.2 to 8.4) compared to those with an SBP of 100 to 119 mmHg. Those with an SBP below 80 mmHg (aHR, 4.5; 95% CI, 1.1 to 18.8) and those with an SBP of 80 to 89 mmHg (aHR, 3.1; 95% CI, 0.9 to 10.2) also had an increased risk of vascular mortality, compared to those with an SBP of 90 to 119 mmHg. This association was sustained when excluding the first two years of follow-up or preexisting vascular diseases. In men younger than 60 years, the association of low SBP was weaker than that in those aged 60 years or older. Conclusions: Our findings suggest that low SBP (<90 mmHg) may increase vascular mortality in Korean men aged 60 years or older.

Association between Korean Medicine Hospital Utilization and Cardiovascular Risks in Patients with Hypertension: a National Korean Cohort Study (고혈압 환자에서 한방의료기관 이용과 심혈관 위험 요소와의 관계: 국민건강보험공단 표본코호트 DB)

  • Cho, Hyunjoo;Jung, Hyejin;Lim, Sabina
    • The Journal of Korean Medicine
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    • v.40 no.3
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    • pp.1-20
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    • 2019
  • Objectives: This study aims to investigate the effects of Korean Medicine Hospital Utilization (KMHU) on major adverse cardiovascular events (MACE), myocardial infarction (MI), stroke, and death in hypertensive patients taking antihypertensives. Methods: Using the Korean National Health Insurance Service-National Sample Cohort database, this study identified and diagnosed 68,457 hypertensive patients taking antihypertensives between 2003 and 2006. They were divided into KMHU and non-KMHU groups. The follow-up period ended with the diagnosis of myocardial infarction, stroke, or death. After propensity score matching (PSM), there were 18,242 patients each in the non-KMHU and KMHU groups. We calculated the incidence rate, hazard ratio (HR), and 95% confidence interval (CI) for MACE, myocardial infarction, stroke, and death in patients with hypertension using a stratified Cox proportional hazard model. In addition, secondary outcome analyses for stroke and cardiovascular mortality were performed. Results: After PSM, the HRs for MACE (HR: 0.84, 95% CI: 0.81-0.87), all-cause mortality (HR: 0.75, 95% CI: 0.72-0.79), and myocardial infarction (HR: 0.90, 95% CI: 0.83-0.97) were significantly lower in the KMHU group than in the non-KMHU group. Moreover, the HRs for stroke-related mortality, haemorrhage and ischaemic stroke-related mortality, and ischaemic heart disease-related and circulatory system disease-related mortality were significantly lower in the KMHU group than in the non-KMHU group. Conclusions: On long-term follow-up observation, this study supported the effect of KMHU for managing hypertension and reducing the burden of cardiovascular diseases.

The Survival of Paid Broadcasting Channels in Korea, 1993-2010

  • Kwak, Kyu Tae;Song, Kyung Hee;Park, Soo Kyung;Lee, Bong Gyou
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.8 no.2
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    • pp.547-566
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    • 2014
  • This study investigates the decisive factors affecting the survival or collapse of cable networks in the Korean paid broadcasting market from 1993 to 2010. The effects of performance variables discussed in previous studies were verified through survival analyses. According to the results, the most influential factors in the survival of cable networks were horizontal integration (MPP), channel genre, the scheduling of HDTV content, and the proportion of access program scheduling. These findings imply that the differentiation strategy of content suppliers is the most decisive factor among all business performance-related factors. Specifically, the content supply power and strategy of the program provider (PP) have the greatest influence on cable network viability. The present study is meaningful as the first attempt to establish the performance of PPs in Korean pay broadcasting markets through the viewpoint of organizational mortality. Accordingly, the present study can supplement the results of cross-sectional studies conducted with smaller samples.

Comparison of Sediment Disaster Risk Depending on Bedrock using LSMAP (LSMAP을 활용한 기반암별 토사재해 위험도 비교)

  • Choi, Won-il;Choi, Eun-hwa;Jeon, Seong-kon
    • Journal of the Korean Geosynthetics Society
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    • v.16 no.3
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    • pp.51-62
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    • 2017
  • For the purpose of the study, of the 76 areas subject to preliminary concentrated management on sediment disaster in the downtown area, 9 areas were selected as research areas. They were classified into three stratified rock areas (Gyeongsan City, Goheung-gun and Daegu Metropolitan City), three igneous rock areas (Daejeon City, Sejong Special Self-Governing City and Wonju City) and three metamorphic rock areas (Namyangju City, Uiwang City and Inje District) according to the characteristics of the bedrock in the research areas. As for the 9 areas, analyses were conducted based on tests required to calculate soil characteristics, a predictive model for root adhesive power, loading of trees and on-the-spot research. As for a rainfall scenario (rainfall intensity), the probability of rainfall was applied as offered by APEC Climate Center (APCC) in Busan. As for the prediction of landslide risks in the 9 areas, TRIGRS and LSMAP were applied. As a result of TRIGRIS prediction, the risk rate was recorded 30.45% in stratified rock areas, 41.03% in igneous rock areas and 45.04% in metamorphic rock areas on average. As a result of LSMAP prediction based on root cohesion and the weight of trees according to crown density, it turned out to a 1.34% risk rate in the stratified rock areas, 2.76% in the igneous rock areas and 1.64% in the metamorphic rock areas. Analysis through LSMAP was considered to be relatively local predictive rather than analysis using TRIGRS.

The Effects of Social Activities and Living Arrangements on Cognitive Functions in Middle-aged and Elderly Adults: A Panel Study Using the 2006-2018 Korean Longitudinal Study of Aging

  • Choi, Yoon-Jung;Hong, Yun-Chul;Do, Young-Kyung
    • Journal of Preventive Medicine and Public Health
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    • v.54 no.6
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    • pp.395-403
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    • 2021
  • Objectives: Previous studies have shown that participation in social activities (SA) can prevent cognitive decline (CD) and that living arrangements (LA) can affect cognitive function. This study aimed to evaluate the effects of SA and LA on CD, as well as their interactions, using longitudinal data. Methods: Data were used from the 2006-2018 Korean Longitudinal Study for Aging, which followed 10 254 adults older than 45 years over a 12-year period. CD was defined as a ≥4-point score decrease in the Mini-Mental Status Exam over 2 years. We developed an extended Cox proportional hazards model for time-dependent covariates to estimate the hazard ratio (HR) of CD in 4 groups: (1) socially active and living with others, (2) socially active and living alone, (3) socially inactive and living with others (SILO), and (4) socially inactive and living alone (SILA). The model was stratified by gender and adjusted for important confounders. Results: The HR of CD was significantly higher in the SILO group in men (HR,1.36; 95% confidence interval [CI], 1.08 to 1.78) and in the SILA group in women (HR, 1.72; 95% CI, 1.08 to 2.75). However, the interaction term for gender was not significant. Conclusions: Among socially inactive elderly adults, the HR of CD was elevated in men who lived with others and in women who lived alone, although the interaction term for gender was not significant. Socially inactive men who live with others and socially inactive women who live alone are particularly encouraged to participate in SA to prevent CD.

Positive Effects of Soy Isoflavone Food on Survival of Breast Cancer Patients in China

  • Zhang, Ya-Feng;Kang, Hong-Bin;Li, Bi-Li;Zhang, Rui-Ming
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.2
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    • pp.479-482
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    • 2012
  • Aim: Soy foods are the major source of isoflavones, which are believed to play important roles in genesis of breast cancer and its progression. We here conducted a prospective study to evaluate the association of soy isoflavone food consumption with breast cancer prognosis. Methods: A prospective study was performed from January 2004 and January 2006 in China. Trained interviewers conducted face-to-face interviews using a structured questionnaire to collect information on dietary habits and potential confounding factors. The relative risk [hazard ratio (HR)] and 95% CI were calculated from the Cox regression model for all significant predictors from cancer diagnosis to the endpoint of the study (event). Results: After a median follow up of 52.1 months (range, 9-60 months), a total of 79 breast cancer related deaths were recorded in our study, risk being inversely associated with a high intake of soy isoflavone. With an average intake of soy isoflavone above 17.3 mg/day, the mortality of breast cancer can be reduced by about 38-36%. We also found the decreased breast cancer death with high soy protein intake, with a HR (95% CI) of 0.71 (0.52-0.98). Stratified analysis with reference to the ER status, further demonstrated a better prognosis of ER positive breast cancer with a high intake of soy isoflavone (HR 0.59, 0.40-0.93). Conclusion: Our study shows the soy food intake is associated with longer survival and low recurrence among breast cancer patients. A cohort study with a larger sample size and long term follow-up is now needed.