• Title/Summary/Keyword: Store Data

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Inhibitory Effects of Ginsenoside-Rb2 on Nicotinic Stimulation-Evoked Catecholamine Secretion

  • Lim, Hyo-Jeong;Lee, Hyun-Young;Lim, Dong-Yoon
    • The Korean Journal of Physiology and Pharmacology
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    • v.18 no.5
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    • pp.431-439
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    • 2014
  • The aim of the present study was to investigate whether ginsenoside-Rb2 (Rb2) can affect the secretion of catecholamines (CA) in the perfused model of the rat adrenal medulla. Rb2 ($3{\sim}30{\mu}M$), perfused into an adrenal vein for 90 min, inhibited ACh (5.32 mM)-evoked CA secretory response in a dose- and time-dependent fashion. Rb2 ($10{\mu}M$) also time-dependently inhibited the CA secretion evoked by DMPP ($100{\mu}M$, a selective neuronal nicotinic receptor agonist) and high $K^+$ (56 mM, a direct membrane depolarizer). Rb2 itself did not affect basal CA secretion (data not shown). Also, in the presence of Rb2 ($50{\mu}g/mL$), the secretory responses of CA evoked by veratridine (a selective $Na^+$ channel activator ($50{\mu}M$), Bay-K-8644 (an L-type dihydropyridine $Ca^{2+}$ channel activator, $10{\mu}M$), and cyclopiazonic acid (a cytoplasmic $Ca^{2+}$-ATPase inhibitor, $10{\mu}M$) were significantly reduced, respectively. Interestingly, in the simultaneous presence of Rb2 ($10{\mu}M$) and L-NAME (an inhibitor of NO synthase, $30{\mu}M$), the inhibitory responses of Rb2 on ACh-evoked CA secretory response was considerably recovered to the extent of the corresponding control secretion compared with the inhibitory effect of Rb2-treatment alone. Practically, the level of NO released from adrenal medulla after the treatment of Rb2 ($10{\mu}M$) was greatly elevated compared to the corresponding basal released level. Collectively, these results demonstrate that Rb2 inhibits the CA secretory responses evoked by nicotinic stimulation as well as by direct membrane-depolarization from the isolated perfused rat adrenal medulla. It seems that this inhibitory effect of Rb2 is mediated by inhibiting both the influx of $Ca^{2+}$ and $Na^+$ into the adrenomedullary chromaffin cells and also by suppressing the release of $Ca^{2+}$ from the cytoplasmic calcium store, at least partly through the increased NO production due to the activation of nitric oxide synthase, which is relevant to neuronal nicotinic receptor blockade.

A Study on System Requirements for Integrated Electronic Document Management System (IEDMS) (통합전자문서체계구현을 위한 요구기능 분석 연구 -A사의 전자문서관리 사례를 중심으로-)

  • 권택문
    • Journal of Information Technology Application
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    • v.2 no.1
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    • pp.55-81
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    • 2000
  • An Electronic Document Management System(EDMS) is an electronic system solution that is used to create, capture, distribute, edit, store and manage documents and related structured data repositories throughout an organization. Recently, documents of any type, such as text, images, and video files, and structured databases can be controlled and managed by an office automation system and an EDMS. Thus, many organizations are already using these information technologies to reduce process cycle-times. But what the organizations are missing is a integrated system the current workflow or office automation system and provides immediate access to and automatic routing of the organization's mission-critical information. This study tried to find out the user's requirements for integrating current information system and relatively new technology, electronic document management system in order to improve business operations, productivity and quality, and reduces waste. integration of electronic document management system(EDMS) and office automation system and proper use of these technological will improve organization's processes, and compress the process cycle-times. For this study a case study was done by a project team in cooperation with a government organization(say A company). Through this case study valuable electronic document management and office automation system requirement have been identified and reported for providing a system model in order to design an Integrated EDMS(IMDMS).

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A Study of Legibility by Monitor Letter Color with an Eye Tracker (아이트래커를 이용한 모니터 글자 색상에 따른 가독성에 대한 연구)

  • Kim, Ha-Rim;Kim, Soo-Hyun;Shin, Dong-Min;Jeong, Hee-Young;Kim, Young-Gil;Kim, Tae-Hong;Seo, Jae-Myoung;Jeong, Ju-Hyun
    • Journal of Korean Ophthalmic Optics Society
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    • v.19 no.2
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    • pp.279-284
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    • 2014
  • Purpose: This study will be a basic research providing data which can reduce eye strain using monitor and electric media by measuring legibility of text color on monitor. Methods: Total experimental subjects who don't have color anomaly and best corrected visual acuity was over 1.0 were 50 and their mean age was $22.83{\pm}1.47$. Reading speed test were carried out with 163 words and subjects who could read over 123 words were selected for legibility examination. Monitor background color was white and letter colors were black, blue, red, and yellow for the legibility examination. Results: In case of text color of black, blue, red, and yellow, Event duration(sec) was measured to 41.89, 42.89, 45.32, and 56.28, respevtively, and reading error (number) was measured to 1.94, 2.74, 3.36, and 5.14. Average of fixation duration(sec) was measured to 0.25, 0.26, 0.27, and 0.32. Conclusions: In this paper, event Duration, reading error and average of fixation duration which can measure the legibility was reduced in a sequence of black blue, red, and yellow.

PARTIAL REPLACEMENT OF GRASS SILAGE WITH WHOLE-CROP CEREAL SILAGE FOR GROWING BEEF CATTLE

  • Raza, S.H.;Rowlinson, P.
    • Asian-Australasian Journal of Animal Sciences
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    • v.8 no.3
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    • pp.281-287
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    • 1995
  • A study was conducted to investigate the effect of different inclusion levels of urea treated whole-crop wheat silage (UWCWS) in grass silage based rations on the performance of growing beef cattle. The winter wheat (variety, Riband) was harvested (in the summer of 1991) at a dry matter proportion of 520 g/kg and treated with feed grade urea at the rate of 37 kg/tonne crop dry matter and preserved in a heavy duty plastic bag using a silo press. The urea treated whole crop wheat silage (UWCWS) was mixed with grass silage to replace 0.00 (S100), 0.33 (S33) and 0.67 (S67) parts of the forage dry matter and fed ad libitum in a cross over design to 18 Simmental X Holstein Friesian growing beef animals. Two energy sources {one high in starch, rolled barley (RB) and one high in digestible fibre, sugar beet pulp (SBP)} were fed to supply sufficient energy for the efficient use of nitrogen by the rumen micro-organisms. The data on DMIF (dry matter intake of forage), TDMI (total dry matter intake), DLWG (daily live weight gain), FCR (feed conversion ratio) were recorded and faecal samples were collected to determine the digestibility coefficients. Results revealed that with the inclusion of UWCW in the animals' diets the DMI of the forage was significantly increased (p < 0.05). The highest DMIF was found in the treatment "S33" ($6.28{\pm}0.25kg$) where 67% of the silage dry matter was replaced with the UWCW and the lowest value for DMIF was observed in the control treatment ($5.03{\pm}0.23kg$). The DLWG did not differ significantly between the treatments. However, treatment "S100" showed a trend towards a superior DLWG. Feed conversion ratio in the control treatment differed significantly from "S67" and "S33". The addition of the UWCW in the animals' diet resulted in the lower FCR There was no effect of type of energy supplement on any aspect of performance either overall or in interaction with grass silage: UWCWS ratio. The regression and correlation coefficients for DMIF (r = 5.22 + 0.0184x*), DLWG (r = $1.04-0.00086x^{NS}$) and FCR (r = 4.78 = 0.022x*) on the inclusion of UWCW in the diet were calculated. The effect of the inclusion of UWCW on the overall digestibility coefficients was significant (p < 0.05). The addition of the UWCWS in the diet decreased the digestibility of the DM, OM, ADF and NFE but effect on the protein digestibility was non significant. The results of present study suggests that a DLWG slightly over 1 kg can be achieved with UWCW during the store period (period in which animal performance targets are low especially during winter) and the prediction of ME was overestimated as the high intake of DM did not reflect in improved animal performance.

A Study on the Process Encounter for Service Quality Control : Focusing on franchise restaurant (서비스품질 관리를 위한 프로세스 접점에 관한 연구 : 프랜차이즈 외식업을 중심으로)

  • Kim, Sang-Cheol
    • Journal of Distribution Science
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    • v.11 no.8
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    • pp.25-30
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    • 2013
  • Purpose - Foodservices have grown to over 60% of the franchise industry. However, despite reaching this high level, the foodservice franchise industry is experiencing severe ups and downs. While factors such as expansion by franchises and the entry of large multinational firms are causing this imbalance, the more serious problem faced by franchisees is the lack of know-how and correct operating procedures. Franchise headquarters should advise franchisees on important matters such as food ingredients, interior design, tableware, and fixtures. However, even though franchise headquarters have the ability to impart such management know-how, this is often a neglected area. Research design, data and methodology - This study was conducted in an industrial environment to present suitable competitive alternatives for foodservice franchises. Empirical analysis was conducted using a sample of 232 people with experience in targeting customers. The main purpose of this study is not to identify and analyze the factors affecting customer satisfaction. Customers of the Food Service Industry to invite contacts until departure for the service flow by identifying the expectations and allow this area by analyzing the resulting measures to enhance the competitiveness has presented. Results - Actual results contact factors affecting the quality of service on customer satisfaction was a significant influence. However, the end of this analysis, the actual customer satisfaction directly affects the quality of service that is only important factor can commit mistakes. Relatively large impact on customer satisfaction, which is relatively independent of the quality factor should be a review of zone of tolerance. In this study, eating phase relative to contact the service customer satisfaction was the most influential. The results, however, zone of tolerance for an area in the waiting and ordering dissatisfaction factors are appearing. And in the course of these services outside the zone of tolerance area is unsatisfactory evaluation is being done. Conclusions - After all, Foodservice, the contact service management for zone of tolerance the top priority should be can be seen. Foodservice contact first in the case of service quality factors caused by the continuous flow of services, so this step-by-step identification needs to be clearer. This, of course, to distinguish between the actual per unit of activity appears to be more difficult to follow, for it seems to need a lot of future complementary. Next is the assessment of customer service quality. Customers remember the experience for the services of a real contact through the assessment and service evaluation clearly emerge as the expected level can be difficult. However, this situation is controlled by the test method cannot be avoided unless there is no limit to the number of leave. Despite these limitations, the next step to contact a service evaluation and analysis have to continue to refine and thereby franchisees for the operation of the store in terms of practical know-how required to provide to the office believe.

Optimization of Multi-reservoir Operation with a Hedging Rule: Case Study of the Han River Basin (Hedging Rule을 이용한 댐 연계 운영 최적화: 한강수계 사례연구)

  • Ryu, Gwan-Hyeong;Chung, Gun-Hui;Lee, Jung-Ho;Kim, Joong-Hoon
    • Journal of Korea Water Resources Association
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    • v.42 no.8
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    • pp.643-657
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    • 2009
  • The major reason to construct large dams is to store surplus water during rainy seasons and utilize it for water supply in dry seasons. Reservoir storage has to meet a pre-defined target to satisfy water demands and cope with a dry season when the availability of water resources are limited temporally as well as spatially. In this study, a Hedging rule that reduces total reservoir outflow as drought starts is applied to alleviate severe water shortages. Five stages for reducing outflow based on the current reservoir storage are proposed as the Hedging rule. The objective function is to minimize the total discrepancies between the target and actual reservoir storage, water supply and demand, and required minimum river discharge and actual river flow. Mixed Integer Linear Programming (MILP) is used to develop a multi-reservoir operation system with the Hedging rule. The developed system is applied for the Han River basin that includes four multi-purpose dams and one water supplying reservoir. One of the fours dams is primarily for power generation. Ten-day-based runoff from subbasins and water demand in 2003 and water supply plan to water users from the reservoirs are used from "Long Term Comprehensive Plan for Water Resources in Korea" and "Practical Handbook of Dam Operation in Korea", respectively. The model was optimized by GAMS/CPLEX which is LP/MIP solver using a branch-and-cut algorithm. As results, 99.99% of municipal demand, 99.91% of agricultural demand and 100.00% of minimum river discharge were satisfied and, at the same time, dam storage compared to the storage efficiency increased 10.04% which is a real operation data in 2003.

Process Performance Measurement Model Based on Event for an efficient Decision-Making (효율적인 의사결정을 위한 이벤트 기반의 프로세스 성과측정을 위한 모델)

  • Park, Jae-Won;Choi, Jae-Hyun;Cho, Poong-Youn;Lee, Nam-Yong
    • The KIPS Transactions:PartD
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    • v.17D no.4
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    • pp.259-270
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    • 2010
  • Information systems nowadays are heterogeneous and distributed which integrate the enterprise information by processes. They are also very complex, because they are linked together by processes. It aims to integrate the systems so that these systems work as one system. A process is a framework which contains all of the business activities in an enterprise, and has a lot of information which is needed for measuring performance. A process consists of activities, and an activity contains events which can be considered information sources. In most cases, it is very valuable to determine if a process is meaningful, but it is difficult because of the complexity in measuring performance, and also because finding relationships between business factors and events is not a simple problem. So it would reduce operation cost and allow efficient process execution if I could evaluate the process before it ends. In this paper we propose an event based process measurement model. First, we propose the concept of process performance measurement, and a model for selecting process and activity indexes from the events which are collected from information systems. Second, we propose at methodologies and data schema that can store and manage the selected process indexes, the mapping methods between indexes and events. Finally, we propose a process Performance measurement model using the collected events which gives users a valuable managerial information.

Design and Implementation of Query Processor for Moving Objects (이동객체를 위한 질의처리 컴포넌트의 설계 및 구현)

  • Kim, Kyoung-Sook;Kwon, O-Je;Byun, Hee-Young;Jo, Dae-Soo;Kim, Tae-Wan;Li, Ki-Joune
    • Journal of Korea Spatial Information System Society
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    • v.6 no.1 s.11
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    • pp.31-50
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    • 2004
  • With the growth of wireless communication networks and mobile devices taking in GPS, Location-Based Service(LBS) is becoming an integral part of mobile applications. LBS can deal with location-aware features such as persons holding mobile phones or vehicles equipped with GPS, and provide the users with the location information of the features. Thus it is necessary to develop moving object database systems to store, manage, and query moving objects which change their locations continuously as time passes. In this paper, we design and implement a query processing component which deals with moving objects as a key data type. For this component, we define a new SQL-like query language(called MOQL) and as a consequence, design and implement modules that analyze and execute queries. It supports various types of operators that process range queries, infer topological relations, compute trajectories, and find k-nearest neighbors. It can be used as a subsystem if other application systems which deal moving objects and also supports ADO.NET interface that can be used to interact end-users.

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Investigating the Monetary Value of Bus Arrival Time Information (실시간 버스도착정보의 가치 측정에 관한 연구)

  • Bin, Mi-Young;Kim, Hyo-Bin
    • Journal of Korean Society of Transportation
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    • v.23 no.6 s.84
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    • pp.81-89
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    • 2005
  • Real-time bus arrival information within the Bus Information System (BIS) is an invaluable resource for users that demand accurate and up-to-date bus headway information while waiting at a bus stop. The associated benefits of such a system come in two folds, that is to 1) resolve the psychological uncertainty caused by the lack of real-time bus arrival information and 2) empower the user waiting at bus stops with the ability to reliably coordinate various tasks and errands, such as a quick trip into a convenience store or restroom without fear of missing a bus pick-up. This paper discusses the appropriate methodology with which to measure the economic value of reliable bus arrival information, with particular emphasis on the psychological uncertainty in users associated with the lack of real-time headway information at bus stops. Data regarding bus transit users' willingness to pay for such a service is obtained through questionnaire surveys, and the Contingent Valuation Method is used to analyze and derive the associated economic value. Our findings indicate the monetary value associated with a real-time bus arrival information system is approximately 132.5 won/min at the 0.3 significance level.

An Effective Employment and Execution Performance Improvement Method of Mobile Web Widget Resources Based on the OMTP BONDI (OMTP BONDI 기반 모바일 웹 위젯 리소스의 효율적 운용 및 구동 성능 개선 기법 연구)

  • Bang, Ji-Woong;Kim, Dae-Won
    • Journal of Korea Multimedia Society
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    • v.14 no.2
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    • pp.153-170
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    • 2011
  • OMTP (Open Mobile Terminal Platform) is a global forum made by telecommunications providers to promote user-oriented mobile services and data business. Devised by OMTP, BONDI is a browser-based application or a mobile web run-time platform to help widgets make good use of functions of mobile devices in a secure way. BONDI enables applications programmed with web standard technologies such as HTML, JavaScript, CSS, and AJAX to reach the internal functions of mobile devices. Since BONDI, which is not just a simple network application, can reach the internal resources of devices in standard ways, it enables the application and widgets to be developed regardless of tile OS or platform. Web browser-based widgets are vulnerable to the network environment, and their exeeution speed can be slowed as the operations of the widgets or applications become heavy. However, those web widgets will be continuously used thanks to the user-friendly simple interface and the faster speed in using web resources more than the native widgets inside the device. This study suggested a method to effectively operate and manage the resource of OMTP BONDI web widget and then provided an improved result based on a running performance evaluation experiment. The experiment was carried to improve the entire operating time by enhancing the module-loading speed. In this regard, only indispensable modules were allowed to be loaded while the BONDI widget was underway. For the purpose, the widget resource list, able to make the operating speed of the BONDI widget faster, was redefined while a widget cache was employed. In addition, the widget box, a management tool for removed widgets, was devised to store temporarily idle widgets.