• Title/Summary/Keyword: Stimulus pattern

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Effects of Systemic and Focal Hypoxia on the Activities of Rostral Ventrolateral Medullary Neurons in Cats

  • Yan, Hai-Dun;Kim, Charn;Kim, Ji-Mok;Lim, Won-Il;Kim, Sang-Jeong;Kim, Jun
    • The Korean Journal of Physiology
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    • v.30 no.1
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    • pp.105-116
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    • 1996
  • Rendering the brain ischemic would evoke the cerebral ischemic reflex which is characterized by an arterial pressor response, apnea and bradycardia. Since the rostral ventrolateral medulla (RVLM) is known to play a key role in the maintenance of normal cardiopulmonary activity, during the cerebral ischemic reflex some cardiac related cells should be excited and respiration related cells inhibited. In this context, the responses of RVLM neurons to systemie and focal hypoxia were analyzed in the present study. Twenty-five adult cats of either sex were anesthetized with ${\alpha}-chloralose$ and the single neuronal activities were identified from RVLM area. For the induction of focal hypoxia in the recording site, sodium cyanide was applied iontophoretically and for systemic hypoxia the animal was ventilated with nitrogen gas for a twenty-second period. Cellular activities were analyzed in terms of their discharge pattern and responses to the hypoxia by using post-stimulus time and single-pass time histograms. Of eighteen cardiac related cells recorded from the RVLM area, twelve cells were excited by iontophoresed sodium cyanide and of twenty-five respiration related cells, fourteen cells were excited by iontophoresed sodium cyanide. Remaining cells were either inhibited or unaffected. Eight of fifteen cells tested with iontophoresed sodium lactate were excited and remaining seven cells were inhibited. Systemic hypoxia induced by nitrogen gas inhalation elevated the arterial blood pressure, but excited, inhibited or unaffected the single neuronal activities. Some cells showed initial excitation followed by inhibition during the systemic hypoxia. Bilateral vagotomy resulted in a decrease of arterial pressor response to the systemic hypoxia, and a slight decrease in the rhythmicity related to cardiac and/or respiratory rhythms. The single neuronal responses to either systemic or focal hypoxia were not affected qualitatively by vagotomy. From the above results, it was concluded that the majority of the cardiac- and respiration- related neurons in the rostral ventrolateral medulla be excited by hypoxia, not through the mediation of peripheral chemoreceptors, and along with the remaining inhibited cells, all these cells be involved in the mediation of cerebral ischemic reflex.

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The Effects of Alcohol on Psychomotor Skill and Driving Behaviors (알코올이 정신운동 및 운전행태에 미치는 영향)

  • Ryu, Jun Beom;Shin, Yong Kyun;Lee, Won Young
    • Journal of Korean Society of Transportation
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    • v.30 no.6
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    • pp.27-36
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    • 2012
  • In Korea, 28,641 cases of traffic accidents were caused by drunk driving in 2010. These statistics accounted for 12.62% of total number of traffic accidents. Moreover, the percentages of deaths and injuries from them were nearly 15% of those from whole traffic accidents. While police has emphasized enforcement efforts in order to reduce drunk driving, culture generous to drunk driving in addition to the absence of an appropriate intervention system for habitual drunk drivers have contributed to the increasing number of the drunk driving accidents in Korea. This study examined specific behavioral changes in drunk driving by comparing drivers' behavior pattern in non-alcoholic condition to those in alcoholic condition, using a psychomotor test and a driving simulator. In the psychomotor test measuring participants' reactions to the target stimulus, it was revealed that participants' correct responses were decreased, false responses were increased, and no responses also were increased after drinking. Furthermore, in the driving simulator performance after drinking, not only driving speed was faster but also the deviation of an accelerator pedal pressure and of the vehicle's lateral position were much increased. These results indicated that alcohol consumption would impair visio-cognitive ability and deteriorate driving safety. Finally, the implications and limitations of our findings and suggestions for the future research were discussed.

Context Modulation Effect by Affective Words Influencing on the Judgment of Facial Emotion (얼굴정서 판단에 미치는 감정단어의 맥락조절효과)

  • Lee, Jeongsoo;Yang, Hyeonbo;Lee, Donghoon
    • Science of Emotion and Sensibility
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    • v.22 no.2
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    • pp.37-48
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    • 2019
  • Current research explores the effect of language on the perception of facial emotion as suggested by the psychological construction theory of emotion by using a psychophysical method. In this study, we hypothesize that the perception of facial expression may be influenced if the observer is shown an affective word before he/she judges an expression. Moreover, we suggest that his/her understanding of a facial emotion will be in line with the conceptual context that the word denotes. During the two experiments conducted for this project, a control stimulus or words representing either angry or happy emotions were briefly presented to participants before they were shown a target face. These target faces were randomly selected from seven faces that were gradually morphed to show neutral to angry (in Experiment 1) and neutral to happy (in Experiment 2) expressions. The participants were asked to perform a two-alternative forced choice (2AFC) task to judge the emotion of the target face (i.e., decide whether it is angry or neutral, or happy or neutral). The results of Experiment 1 (when compared with the control condition) showed that words denoting anger decreased the point of subjective equality (PSE) for judging the emotion of the target as anger, whereas words denoting happiness increased the PSE. Experiment 2, in which participants had to judge expressions on a scale from happy to neutral, produced a contrasting pattern of results. The outcomes of this study support the claim of the psychological construction theory of emotion that the perception of facial emotion is an active construction process that may be influenced by information (such as affective words) that provide conceptual context.

Effect of Fingertip Temperature on Multi-finger Actions in Young Adults (손 끝 온도변화가 젊은 성인의 다중 손가락 동작에 미치는 효과)

  • Shin, Narae;Xu, Dayuan;Song, Jun Kyung;Park, Jaebum
    • Korean Journal of Applied Biomechanics
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    • v.29 no.3
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    • pp.157-166
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    • 2019
  • Objective: This study examined the effects of stimulating fingertip temperature on the patterns of force sharing and stability properties during multi-finger force production tasks. Method: 9 adult subjects (male: 3, female: 6, age: $26.11{\pm}4.01yrs$, height: $169.22{\pm}5.97cm$, weight: $61.44{\pm}11.27kg$) participated in this study. The experiment consisted of three blocks: 1) maximal voluntary contraction (MVC) task, 2) single-finger ramp task to quantify enslaving (i.e., unintended force production by non-task fingers), and 3) 12 trials of multi-finger steady-state force production task at 20% MVC. There were three temperature conditions including body-temperature (i.e., control condition), $40^{\circ}C$, and $43^{\circ}C$, and the stimulation was given to the index finger only for all experimental conditions. Results: There were no significant differences in the MVC forces, enslaving, and the accuracy of performance during the steady-state task between the conditions. However, the share of stimulated index finger force increased with the index fingertip temperature, while the share of middle finger force decreased. Also, the coefficient of variation of both index and middle finger forces over repetitive trials increased with the index fingertip temperature. Under the framework of the uncontrolled manifold (UCM) hypothesis used to quantify indices of multi-finger synergies (i.e., stability property) stabilizing total force during the steady-state task, the two variance components within the UCM analysis increased together with the fingertip temperature, while no changes in the synergy indices between the conditions. Conclusion: The current results showed that fingertip temperature stimulation only to index finger does not affect to muscle force production capability of multi-finger, independence of individual fingers, and force production accuracy by the involvement of all four fingers. The effect of fingertip temperature on the sharing pattern and force variation may be due to diffuse reflex effects of the induced afferent activity on alpha-motoneuronal pools. However, the unchanged stability properties may be the reflection of the active error compensation strategies by non-stimulated finger actions.

Modeling for Nuclear Energy for IoT Systems as Green Fuels in Mitigating COVID-19 (COVID-19 완화를 위한 녹색 연료로서 IoT 시스템용 원자력 에너지 모델링)

  • Jang, Kyung Bae;Baek, Chang Hyun;Woo, Tae Ho
    • Journal of Internet of Things and Convergence
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    • v.7 no.2
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    • pp.13-19
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    • 2021
  • It is analyzed that the energy pattern is affected by the social matters of the disease trend where the energy consumption has been reduced following the depression of the national economy. The campaign of social distance for the people has been done by voluntary or legally due to the epidemic of the Coronavirus Disease 2019 (COVID-19). Some economic stimulus policies have been done in some countries including the United States, South Korea, and some others. It is shown the susceptible, infectious, and recovered (SIR) modeling applied by system dynamics (SD) where the logical modeling is constructed with S, I, and R. Especially, the I is connected with Society including Population, Race, and Maturity. In addition, Economy and Politics are connected to Income, GDP, Resources, President, Popularity, Ruling Government, and Leadership. The graph shows the big jump on 2020 April when is the starting month of the S value multiplication. This shows the effect of the COVID-19 and its related post-pandemic trend. The trends of OECD and non-OECD are very similar and the effect of the virus hazards causes significantly to the economic depressions.

A Study on the Economic Efficiency of Tourism Industry in China's Bohai Rim Region Using DEA Model (DEA 모델을 이용한 중국 환 발해만 지역 관광산업의 경제효율성에 관한 연구)

  • Li Ting;Jae Yeon Sim
    • Industry Promotion Research
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    • v.8 no.4
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    • pp.267-276
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    • 2023
  • Based on the tourism input-output data of five provinces and cities in China's Bohai Rim region from 2015~2021, this study analyzes the efficiency of regional tourism using DEA-BCC and DEA-Malmquist index, as well as its contribution to regional economic efficiency, and identifies factors influencing the comprehensive efficiency. The research results indicate that the comprehensive efficiency of the tourism industry in the China Bohai Sea region has reached an optimal level of 88.9%, but there is still room for improvement, with overall fluctuations. The overall productivity of the tourism industry exhibits a "U"-shaped fluctuating pattern, with growth mainly driven by technological advancements. Due to the impact of the COVID-19 pandemic, the region experienced a nearly 50% decrease in total factor productivity in 2019~2020. However, in 2021, with the implementation of various government stimulus policies, the tourism efficiency rapidly recovered to 80% of pre-pandemic levels. In terms of the impact of the tourism industry on the regional economy in the China Bohai Sea region, Hebei Province stands out as a significant contributor. Based on the aforementioned research findings, the following recommendations are proposed in three aspects: optimizing the supply structure, increasing innovation investment, and strengthening internal collaboration. These recommendations provide valuable insights for enhancing regional tourism efficiency and promoting regional synergy.

An Analysis of Urie Consciousness and Behavioral Pattern in Close Relationships of the Korean People (한국인의 대인관계에서의 기본도덕으로서의 의리분석 : 한국인에게 진정한 친구는 의리있는 친구인가)

  • Kibum Kim;Mee Hee Kim;Sang-Chin Choi
    • Korean Journal of Culture and Social Issue
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    • v.8 no.1
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    • pp.79-101
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    • 2002
  • The present study was to investigate the psychological characteristics of Urie(義理; interpersonal morality) in Korean interpersonal relationships in terms of qualitative approach and quantitative approach. In study 1, the authors developed an open-ended questionnaire focused on Urie behavior and not Urie behavior. The results revealed that helping, trusting, and caring behaviors and historicality were the key elements of Urie relationships. On the other hand, selfish and distrusting behaviors disrupted Urie relationships. In study 2, the authors conducted video experiment in order to study how the subjects interpret and understand Urie phenomenon. This video stimulus composed of love and friendship. The main characters showed their conflicts between love and friendship. Thus, subjects were asked to answer their interpretations and understandings about what was going on according to the scene. In study 3, we made three kinds of scenarios which were constituted in conflict situation between close friends who works together at their own company. If one asks some favors to you against social justice, how do you do? Most subjects evaluated the whistle blowing behavior as moral and just. However, they evaluated the insider as not good friend. They evaluated one who did favor even though that behavior was socially unjust as good friend and having Urie. Consequently, Korean people emphasize on their human relationships in everyday life. Urie relationship is built in close and Cheong relationship.

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Consistency of Responses to Affective Stimuli Across Individuals using Intersubject Representational Similarity Analysis based on Behavioral and Physiological Data (참가자 간 표상 유사성 분석을 이용한 정서 자극 반응 일치성 비교: 행동 및 생리 데이터를 기반으로)

  • Junhyuk Jang;Hyeonjung Kim;Jongwan Kim
    • Science of Emotion and Sensibility
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    • v.26 no.3
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    • pp.3-14
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    • 2023
  • This study used intersubject representational similarity analysis (IS-RSA) to identify participant-response consistency patterns in previously published data. Additionally, analysis of variance (ANOVA) was utilized to detect any variations in the conditions of each experiment. In each experiment, a combination of ASMR stimulation, visual and auditory stimuli, and time-series emotional video stimulation was employed, and emotional ratings and physiological measurements were collected in accordance with the respective experimental conditions. Every pair of participants' measurements for each stimulus in each experiment was correlated using Pearson correlation coefficient as part of the IS-RSA. The results of study revealed a consistent response pattern among participants exposed to ASMR, visual, and auditory stimuli, in contrast to those exposed to time-series emotional video stimulation. Notably, the ASMR experiment demonstrated a high level of response consistency among participants in positive conditions. Furthermore, both auditory and visual experiments exhibited remarkable consistency in participants' responses, especially when subjected to high arousal levels and visual stimulation. The findings of this study confirm that IS-RSA serves as a valuable tool for summarizing and presenting multidimensional data information. Within the scope of this study, IS-RSA emerged as a reliable method for analyzing multidimensional data, effectively capturing and presenting comprehensive information pertaining to the participants.

The Clinical Examination of Netspeg Lens for Good Visual Acuity (시력 개선을 위한 Netspeg 렌즈의 임상적 검증)

  • Kim, Douk-Hoon;Bae, Han-Young;Kim, Sun-Tae
    • Journal of Korean Ophthalmic Optics Society
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    • v.11 no.3
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    • pp.281-291
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    • 2006
  • The aim of this study was performed the clinical test using Netspeg lens for good visual acuity on subjects with abnormal refraction status. The subjects of one hundreds adults (fifty males, fifty females, mean=21 years, range=19 to 24) were recorded. The subjects were researched the history including the systemic health, medication, genetics, allergy, systemic disease and ocular disease. The refraction test was recorded the monocular and binocular using objective method. Visual acuity was performed the binocular status using the Netspeg lens and CR-39. Stereopsis test was performed the titmus fly and TNO at near distance using Netspeg lens and CR-39. The P-VEP test was used the 16 pattern size(Bausch Lomb, production in USA) with three channels. Also Subjects viewed the p-vep stimulus with binocular vision through the corrected visual acuity using the Netspeg lens and CR-39. The contrast sensitivity test was performed the contrast sensitivity chart(pelli-Robertson, USA) at 1m distance using the Netspeg lens and CR-39. The ultrastructure of surface on the Netspeg lens and CR-39 was observed the SEM(JMS-5800, made in Japan). The results of this study was as follows: 1. In corrected visual acuity of abnormal refraction using the Netspeg lens and CR-39, the Netspeg lens wearer were acquired the good visual field and clear visual acuity comparative to CR-39 wearer in the subject vision test. however the comfort of visual acuity was similar results in the Netspeg lens and CR-39. Also the subjects of Netspeg lens wearer was good visual acuity more than CR-39 wearer and in the analysis of P-VEP, the amplitude of wave on Netspeg lens used appears to be better through the CR-39(p>0.5). Besides, on the contrast sensitivity, the Netspeg lens wearer was good results than CR-39. The value on stereopsis with TNO by Netspeg lens wearer was better than CR-39 in results. However, in the stereopsis test with Titmus, the Netspeg lens and CR-39 wearer was similar results. 2. The ultrastructure of Netspeg lens surface was the smooth and fine shape more than CR-39. Also, Netspeg lens have a fine line structure in ultrastructure. In conclusion, the results of this study conformed that the surface ultrastructure of Netspeg lens used is more specific pin hole design structure than CR-39. This study indicated that the vision of Netspeg lens used have a better than CR-39 in the corrected visual acuity for abnormal refraction eye. Therefore, In this paper, we suggested that the ultrastructure and line structure of Netspeg lens was related to good visual function. However the visual function of the aspheric Netspeg and ultra waterproof Netspeg lens was similar results.

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Sequential Pituitary Hormone Responses to Electroconvulsive Therapy (전기경련요법후 뇌하수체 호르몬의 순차적인 분비 반응)

  • Kim, Doh Kwan;Kim, Soo Jeong;Choi, Do Sun;Bok, Hae-Sook;Kim, Seungtai Peter
    • Korean Journal of Biological Psychiatry
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    • v.3 no.2
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    • pp.288-294
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    • 1996
  • Background : Most studies of the pituitary hormonal responses to electroconvulsive therapy(ECT) have used limited blood sampling schedules. Little is known about the precise sequence of neuroendocrine events immediately following en ECT application. or about the regulation of the hormonal responses. Methods : Blood was sampled at three minute intervals from eleven patients(two schizophrenics and nine affective disorder patients) undergoing ECT. Each sample was immunologically assayed for arginine vasopressin(AVP), adrenocorticotropic hormone(ACTH), prolactin(PRL), and cortisol. Baseline hormone concentrations and several measures of response were determined for each hormone. The temporal and quantitative relationships among the hormonal responses were determined. Correlations were calculated between seizure duration and secretory responses. Results : All four hormones demonstrated significant secretory responses to ECT, with AVP increasing from 1.2 to 33.3pg/ml(P<0.001), ACTH from 5.4 to 32.3fmol/ml(P<0001). PRL from 21.8 to 102.2ng/ml(P<0.005) and cortisol from 20.1 to 31.1ug/dl(P<0.001). The three pituitary hormones showed consistent time courses of secretion with onset of responses by three minutes but clearly differing peak times of 3, 6, and 12-15 minutes for AVP, ACTH, and PRL, respectively. Cortisol began to rise after 6minutes and pecked between 20-30minutes. There ware no significant correlations between seizure duration and any of the secretory response measures. Conclusions : 1) The pituitary hormone response to ECT is sequential rather than synchronous 2) The AVP response was extremely rapid and more massive than those of any other hormones. 3) The ACTH response of this study was more rapid and mare robust than thai revealed by the mast of past studies. 4) The results strongly suggest that the pituitary hormones are released as a result of the seizure rather tho, the electrical stimulus. 5) The sequential pattern of responses suggests that neuroendocine feedback-regulatory mechanisms determine the response profile.

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