• Korean Journal of Veterinary Research
• /
• v.17 no.1
• /
• pp.9-12
• /
• 1977

To study the effects of oxytocin and three parasympathomimetic drugs such as neostigmine, bethanechol, and pilocarpine in reduction of interval between birth and incidence of intrapartum stillborn pigs, 213, sows and gilts which had been kept under the same condition, were randomly allotted to 4 treatment and one control groups. The side reactions of three parasympathomimetic drug were also examined. The results obtained were summarized as followings. 1. Parasympathomimetic-treated groups revealed tendence to shorter interval between birth than oxytocin-treated or control groups. 2. Stillbirth rate per litter was significantly less (p<0.01) in the parasympathomimetic-treated groups than in the oxytocin-treated or control groups. 3. Moderate to severe salivation and vomiting were found in many clams of the pilocarpine-treated and bethanecol-treated groups. The neostigmine-treated group showed nearly no side reaction and neostigmine found to the safest among three parasympathomimetic drugs.

• Asian-Australasian Journal of Animal Sciences
• /
• v.18 no.10
• /
• pp.1475-1478
• /
• 2005

Statistical analysis was conducted on sow stillbirth traits of three genotypes with 2,400 litters including the Erhualian, Large White and the $F_1$ cross of these two breeds. Number of stillborn piglets per litter in the Erhualian, Large White and the $F_1$ averaged 0.85, 0.31 and 0.70, and percentage born alive averaged 95.0%, 97.0% and 95.5%, respectively. Erhualian sows with a greater litter size also had a higher stillbirth rate. Results of analysis of variance indicated that genotype, parity, farrowing year${\times}$farrowing season interaction and total number born had highly significant effects on both number of stillborn piglets per litter and percentage born alive in sows (p<0.0001). Farrowing year had no significant effect on number of stillborn piglets per litter (p>0.05), and highly significant effect on percentage born alive (p<0.01). Farrowing season had highly significant effects on both number of stillborn piglets per litter and percentage born alive (p<0.01). From parity one to parity ten, least squares means for number of stillborn piglets per litter progressively increased with increasing parity and least squares means for percentage born alive progressively decreased with increasing parity. Sows that farrowed in winter had the highest number of stillborn piglets per litter and the lowest percentage born alive, sows that farrowed in autumn had the lowest number of stillborn piglets per litter and the highest percentage born alive. With increasing total number born, least squares means for number of stillborn piglets per litter markedly increased and least squares means for percentage born alive markedly decreased. Results from analysis of paternal half sibs indicated that the heritabilities for number of stillborn piglets per litter and percentage born alive were 0.110 and 0.124, and the genetic, phenotypic and environmental correlations between them were -0.989, -0.951 and -0.948, respectively. These results indicated that number of stillborn piglets per litter and percentage born alive were traits with the similar genetic background.

• Animal Bioscience
• /
• v.34 no.11
• /
• pp.1749-1756
• /
• 2021

Objective: Microminipig (MMP) is a miniature pig with an extra small body size for experimental use. In the present study, the occurrence of stillbirths and their genetic association with swine leukocyte antigen (SLA) class II haplotypes were evaluated in a population of MMPs. Methods: The occurrences of stillbirth and genetic association with SLA class II haplotypes using 483 stillborn and 2,246 live piglets, and their parents were compared among the three groups of newborn piglet litters; an all stillborn (AS) group consisting of only stillborn piglet litters, a partial stillborn (PS) group consisting of stillborn and live piglet litters, and an all alive (AA) group consisting of only live piglet litters. Results: The incidence of stillborn piglets was 483/2,729 (17.7%). Distributions of litter sizes, numbers of stillborn piglets in a litter, parities, and gestation periods were distinct among the three groups. The frequencies of low resolution haplotype (Lr)-0.7 or Lr-0.23 were higher in the AS group than in the PS or AA groups. In sires, the frequency of Lr-0.7 associated with the AS group was significantly higher in the AS group than with the AA group. In dams, the frequency of Lr-0.23 was significantly higher in the AS group than in the PS or AA groups, whereas the frequency of Lr-0.7 was not significantly different. Conclusion: The incidence of stillborn piglets in MMPs appears to be higher than those in other pig breeds. Several traits related with stillbirths such as the number of stillborn piglets and parities of the AS group were different from those of the PS and AA groups. Specific SLA class II haplotypes were associated significantly with a high incidence of stillbirths and could be used as genetic markers to adopt breeding strategies to lower the rate of stillbirth in MMPs.

• Biomolecules & Therapeutics
• /
• v.5 no.3
• /
• pp.253-259
• /
• 1997

The effect of corticosteroid on the diabetic pregnant rats and their fetuses was investigated. Streptozotocin (STB) was injected into the pregnant rats on the fifth day of pregnancy. Dexamethasone (DXM) was injected into the pregnant rats on the 17th, 18th, 19th and 20th days of pregnancy In prenatal rats, the body weight, an abortion rate, number of fetus, the ratio of lecithin/sphingomyelin (L/S) and the levels of blood glucose and phosphatidylglycerol (PG) were determined. In the postnatal rats, the body weight, the levels of blood glucose, fetal number, stillbirth rate, an organ weight and the levels of hepatic glycogen, protein and triglyceride were determined. The body weight of fetuses was lower in the DXM group and higher in the STZ group than the those of control group. Blood glucose of fetuses produced hypoglycemia in the STZ group compared with the control group. A significant increase in the abortion and stillbirth rates was observed in STZ group. The levels of glycogen, protein and triglyceride in fetus liver and the weight of pancreas were significantly increased in the 572 and STZ+DXM groups compared with the control group. The L/S ratio and the level of PG in the amniotic (quid were significantly decreased in STZ group compared with the control group, whereas those of the STZ+DXM group were similar to the control group. It has been observed that corticosteroid administration on the STZ-induced diabetic rats during final stage of pregnancy can prevent the respiratory depression syndrome of neonatal rats.

• Journal of Embryo Transfer
• /
• v.14 no.3
• /
• pp.211-217
• /
• 1999

The objective of this study was to determine the cause and prevalence of bovine abortion and stillbirth in Kyungi-do area. Seventy three bovine fetuses were collected from farms and submitted to the College of Veterinary Medicine, Seoul National University. Submitted fetuses were evaluated during a 4-month period (July to November, 1999) for pathological lesion, tissue protozoa, bacteria and viral infection. The average proportion of abortions was decreased with parity in 73 abortion heifers and cows. Monthly incidence rate of bovine abortion was not different in this study. In fetuses from 90 to 282 days gestation, the majority were between 150 and 250 days gestation(58%). The cause of abortion or stillbirth was determined in 51% of the cases examined. In 15(21%) of the fetus, neosporosis were diagnosed by pathological findings. In three (4%) additional fetuses in three additional fetuses, suspected Neosporosis by pathological lesion, and in 3 (4%) fetuses examined Neopsorosis were diagnosed in 15 feturses and in 3 fetuses, Neosporosis was suspected by pathological legions. Neosporosis / viral infection were diagnosed in three additional fetuses). Miscellaneous bacterial infection, BVDV, iatrogenic cause, Neosporosis / IBRV / BVDV, miscellaneous viral, IBRV/BVDV and others were 3(4%), 3(4%), 2(3%), 2(3%), 1(1%), 1(%) and 9(12%) respectively. The cause and incidence of bovine abortion in different area in Kyungi-do was not different in this study.

• Journal of Veterinary Clinics
• /
• v.37 no.6
• /
• pp.324-330
• /
• 2020

Few studies of the side effects of the FMD vaccine have been performed domestically and studies in accordance to region have been limited. This study was performed by inoculating cows raised in the Daejeon province with the FMD vaccine and observing the side effects following inoculation. From January to February of 2011, 3,378 cows vaccinated with the FMD vaccine, in 143 different farms in the Daejeon province were analysed for adverse effects after inoculation. A total of 66 cows showed adverse effects after the first FMD vaccination and adverse effects observed were abortion/stillbirth (24, 36.4%), death (19, 28.8%), premature birth (14, 21.2%), skin lesions (8, 12.1%), vaginal swelling (1, 1.5%). A total of 29 cows showed adverse effects after the second FMD vaccination and adverse effects observed were abortion/stillbirth (17, 58.6%), premature birth (5, 17.2%), facial swelling (4, 13.8%), death (3, 10.3%). Through these results, continuous national research of the side effects of the FMD vaccine should be carried out continuously henceforth.

• Journal of Trauma and Injury
• /
• v.36 no.3
• /
• pp.281-285
• /
• 2023

Traumatic uterine rupture is uncommon but can be fatal and life-threatening for both the mother and infant. In addition to complications caused by trauma itself, such as pelvic fracture, gestational complications such as placental abruption, abortion, premature labor, rupture of membranes, maternal death, and stillbirth can occur. In particular, fetuses have been reported to have a high mortality rate in cases of traumatic uterine rupture. A 35-year-old pregnant female patient fell from the fourth floor and was admitted to our trauma center. We observed large hemoperitoneum, pelvic fractures, and spleen laceration, and the fetus was presumed to be located outside the uterus. The pregnant woman was hemodynamically unstable. Although the fetus was stillborn, angioembolization and surgical treatment were properly performed through collaboration with an interventional radiologist, obstetrician, and trauma surgeons. After two orthopedic operations, the patient was discharged after 34 days. This case report suggests the importance of a multidisciplinary approach in the treatment of pregnant trauma patients.

• Clinical and Experimental Reproductive Medicine
• /
• v.3 no.1
• /
• pp.5-11
• /
• 1976

Considerable data has been reported on the outcome of pregnancies subsequent to induced abortion, but the findings contain a great deal of inconsistency and disagreement. Most studies strongly suggest that normal deliveries are less likely to occur in subsequent pregnancies following induced abortion, in terms of gestation length, birth weight, stillbirth, and miscarriage. Other work suggests that some of the demographic and health characteristics of women who experience induced abortion are different from those women who do not; and these factors may affect the outcome of subsequent pregnancies profoundly rather than the induced abortion itself.

• Korean Journal of Veterinary Service
• /
• v.14 no.1
• /
• pp.19-26
• /
• 1991

A considerably high rate of abnormal deliveries of unknown etiology was observed among dairy cattles from November 1988 to February 1989 and Korean native tattles from January to April 1990. The abnormal deliveries consisted of abortions, stillbirths and calf deformities refers to as congenital arthrogryposis hydranencephaly (AH )syndrome. In order to know the level of Akabane antibody of dairy cattle raised in Kyungbuk province, serum neutralization test was conducted with Akabane virus(OBE-1 strain) and HmLu(Hamster lung) cell line. The results were summarized as follows. 1. During 4 months(Nov. 1988-Feb. 1989), abortion (3 heads), stillbirth(1 head) and congenital abnormalities(13 heads) of newborn were occurred in 17 dairy cattles raised in Kyungbuk province. 2. During 4 months(Jan.-Apr.1990), stillbirth(2 heads) and congenital deformities (13 heads) of newborn were occurred in 15 Korean native tattles raised in Kyungbuk province. 3. In Fev, and Apr. 1990, 1,005 dairy cattles at 99 farms were investigated on the actual condition of possessing Akabane antibody. The result was that 1,000 heads (99.9%) in 1,005 dairy cattles reacted as positive condition in Akahane antibody. The antibody titer was from 4 to over 256. 4. 189 heads (18.8%) of 1,005 dairy cattles werw below antibody titer 8 and 816 heads (81.2%) were over 16. 5. Akabane antibody titer of east coast legions(Pohang Yeongil etc) was all over 16, that of internal legions (Yeongiu, Andong. etc) was relatively low, The result suggest that the vaccination for Akabane disease will be unnecessary for the time being because of possessing higher antibody titer reaction except the newly introduced cattle and Akabane virus was widely disseminated in kyungbuk province during the summer months in 1987 or 1988.

• Journal of the korean veterinary medical association
• /
• v.24 no.3
• /
• pp.163-171
• /
• 1988

A swine farm located in Namyangju, Kyunggi-do was damaged by increased loss due to stillbirth, abortion and high mortality of suckling pig during October to December 1987. Three piglets of the farm, that were diagnosed clinico-pathologically to be affecte