• Title/Summary/Keyword: Statistical Testing

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Sensitivity of Whole-Blood Interferon-Gamma Release Assay According to the Severity and the Location of Disease in Patients with Active Tuberculosis (활동성 결핵의 중증도 및 병변 부위에 따른 전혈 인터페론 감마 분비능 측정의 민감도)

  • Kim, Yi-Young;Lee, Jae-Hee;Lee, Yoon-Jee;Lee, So-Yeon;Lee, Yong-Hun;Choi, Keum-Ju;HwangBo, Yup;Cha, Seung-Ick;Park, Jae-Yong;Jung, Tae-Hoon;Park, Jun-Sik;Kim, Chang-Ho
    • Tuberculosis and Respiratory Diseases
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    • v.70 no.2
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    • pp.125-131
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    • 2011
  • Background: The clinical manifestation of $M.$ $tuberculosis$ infection ranges from asymptomatic latent infection, to focal forms with minimal symptoms and low bacterial burdens, and finally to advanced tuberculosis (TB) with severe symptoms and high bacillary loads. We investigated the diagnostic sensitivity of the whole-blood interferon-${\gamma}$ release assay according to the wide spectrum of clinical phenotypes. Methods: In patients diagnosed with active TB that underwent $QuantiFERON^{(R)}$ (QFT) testing, the QFT results were compared with patients known to be infected with pulmonary tuberculosis (P-TB) and extra-pulmonary TB (EP-TB). In addition, the results of the QFT test were further analyzed according to the radiographic extent of disease in patients with P-TB and the location of disease in patients with EP-TB. Results: There were no statistical differences in the overall distribution of QFT results between 177 patients with P-TB and 84 patients with EP-TB; the positive results of QFT test in patients with P-TB and EP-TB were 70.1% and 64.3%, respectively. Among patients with P-TB, patients with mild extents of disease showed higher frequency of positive results of QFT test than that of patients with severe form (75.2% vs. 57.1%, respectively; p=0.043) mainly due to an increase of indeterminate results in severe P-TB. Patients with TB pleurisy showed lower sensitivity by the QFT test than those with tuberculous lymphadenitis (48.8% vs. 78.8%, respectively; p=0.019). Conclusion: Although QFT test showed similar results between overall patients with P-TB and EP-TB, individual sensitivity was different according to the radiographic extent of disease in P-TB and the location of disease in EP-TB.

The Effects of CSR and Firm Reputation of Financial Institutions on Loyalty: Focusing on the Mediation Effect of Trust (금융기관의 사회적 책임과 기업명성이 기업충성도에 미치는 영향: 기업신뢰의 매개효과)

  • Kim, Seong Wook;Ha, Kyu Soo
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.10 no.3
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    • pp.27-38
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    • 2015
  • Recently, Corporate Social Responsibility(CSR) is essential firm activity to establish favorable firm true and sustainability management. However, there has been a controversy over the relationship between CSR and financial performance, also, it has been a little research that investigate relationship between CSR, firm reputation in firm level and firm true, firm loyalty in financial institution. This paper investigate empirically relationship between CSR activities, firm reputation and firm loyalty, moderating effect of firm true on the relationship between CSR activities, firm reputation and firm loyalty. Results were computed using SPSS 20.0 statistical analysis programs. The results are summarized as follows. First, The elements of CSR activities are divided into four factor, such as economic, ethical, consumer protection and environmental responsibilities. In the results of the analyses, consumer protection responsibility, economic reliability and business management skill positive affects the reliability of firm. Second, testing its mediating role, I use the three regression equation models by Baron and Kenny. When the mediator effect of firm true on firm loyalty was represented, the effect of CSR and firm reputation was statistically significant or diminished. Thus, the mediating role of firm true was supported. It means the higher the CSR and corporation reputation activities are, the higher the firm true is, further the higher level of firm true can enhance firm loyalty.

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A study on the user's emotional change when they are using a product by using emotional word logging software (감성어휘 로깅 소프트웨어를 이용한 제품 사용중 사용자의 감성변화 연구)

  • Jeong, Sang-Hoon;Lee, Kun-Pyo
    • Science of Emotion and Sensibility
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    • v.9 no.spc3
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    • pp.167-177
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    • 2006
  • In this study, we developed a tool for measuring user's emotions expressed while using a product in the natural and accessible environment for the design field. Also, using emotional word logging software VideoTAME, we measured a user's emotions expressed while using a product. In the testing module of VideoTAME, participants evaluate their emotional changes through playing and watching the video clips of their performing tasks in the experiment room. In the analyzing module, the researchers replay the results created by participants during the experiment and analyze the results using Microsoft Excel. In this research, we have asked users to examine their emotional changes while watching the recorded video clip of them in the experiment room performing a series of tasks using a cellular phone. In this experiment, there were no big differences in the representative emotions expressed for each characteristics of task. The reason for this can be assumed it is because of the emotional changes occurred while facing specific situations when performing a task rather than the task itself. If more data is collected and concrete statistical analysis is done, it is expected that we can clarify what effect a product's usability has on user's emotions.

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Factors Affecting Acceptance of Smart Farm Technology - Focusing on Mediating Effect of Trust and Moderating Effect of IT Level - (스마트 팜 기술수용에 영향을 미치는 요인 - 신뢰성의 매개효과 및 IT 수준의 조절효과를 중심으로 -)

  • Kang, Duck-Boung;Chung, Byoung-Gyu;Heo, Chul-Moo
    • Korean Journal of Organic Agriculture
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    • v.28 no.3
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    • pp.315-334
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    • 2020
  • This study was conducted to analyze factors affecting acceptance of smart farm technology. Smart farm technology is rapidly being introduced to agriculture in accordance with the progress of the 4th Industrial Revolution, but research on this is still little. Therefore, in this study, based on the unified theory of acceptance and use of technology (UTAUT), a research model reflecting the characteristics of smart farm technology was constructed. To test this, empirical analysis was performed. A survey was conducted for students in smart farm technology education and adult male and female farmers who are currently planning to operate smart farms. Valid 204 sample were used for analysis. The hypothesis test was based on multiple regression analysis using SPSS 24 statistical package. For the mediating effect and moderating effect, Process Macro 3.4 based on the regression equation was used. The results of testing the hypothesis are as follows. First, in the causal hypothesis test, it was shown that performance expectancy, social influence and price value have a significant positive effect on the intention to use smart farm technology. On the other hand, effort expectancy, facilitating conditions were not tested for a significant influence on the use of smart farm technology. As a result of analyzing the mediating effect of trust, it was found that trust plays a mediating role between performance expectancy, effort expectancy, social influence, facilitating conditions, price value and intention to use smart farm technology. In particular, the effort expectancy has not been tested for a direct significant effect on intention to use smart farm technology, but it has been shown to have an impact through trust. Trust was found to be a full mediating between the effort expectancy and the intention to use the smart farm technology. The current IT level of prospective users has been shown to play a moderating role between performance expectancy, facilitating conditions and intention to use smart farm technology. In particular, the IT level was found to strengthen the relationship between performance expectancy and intention to use smart farm technology. Based on the results of these studies, academic and practical implications were suggested.

Comparison of Principal Component Regression and Nonparametric Multivariate Trend Test for Multivariate Linkage (다변량 형질의 유전연관성에 대한 주성분을 이용한 회귀방법와 다변량 비모수 추세검정법의 비교)

  • Kim, Su-Young;Song, Hae-Hiang
    • The Korean Journal of Applied Statistics
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    • v.21 no.1
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    • pp.19-33
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    • 2008
  • Linear regression method, proposed by Haseman and Elston(1972), for detecting linkage to a quantitative trait of sib pairs is a linkage testing method for a single locus and a single trait. However, multivariate methods for detecting linkage are needed, when information from each of several traits that are affected by the same major gene are available on each individual. Amos et al. (1990) extended the regression method of Haseman and Elston(1972) to incorporate observations of two or more traits by estimating the principal component linear function that results in the strongest correlation between the squared pair differences in the trait measurements and identity by descent at a marker locus. But, it is impossible to control the probability of type I errors with this method at present, since the exact distribution of the statistic that they use is yet unknown. In this paper, we propose a multivariate nonparametric trend test for detecting linkage to multiple traits. We compared with a simulation study the efficiencies of multivariate nonparametric trend test with those of the method developed by Amos et al. (1990) for quantitative traits data. For multivariate nonparametric trend test, the results of the simulation study reveal that the Type I error rates are close to the predetermined significance levels, and have in general high powers.

Methods of Combining P-values for Multiple Endpoints of Various Data Types (제 3상 임상시험에서 여러 형태 반응변수의 다변량 검정법인 P값 병합법)

  • Kim, Su-Young;Song, Hae-Hiang
    • The Korean Journal of Applied Statistics
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    • v.21 no.1
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    • pp.35-51
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    • 2008
  • Comparative studies in Phase III clinical trials quite often involve two or more equally important endpoints, and one cannot select primary endpoint from them. O'Brien(1984) proposed for continuous endpoints the OLS and GLS statistics as milti-variate test statistics. Pocock et al. (1987) mentioned the possibility of analyzing a mixture of data types, such as quantitative, binary and survival data types, with the OLS and GLS statistics, but the authors did not explore problems in combining several endpoints of different types. Furthermore, they did not perform a simulation study to assess the efficiencies of the OLS and GLS statistics for endpoints of a mixture of data types. In this paper, we propose the combining methods of correlated P-values for the analysis of multiple endpoints, and compare the efficiencies of this method with those of OLS and GLS statistics for a mixture of data types with a simulation study. Among the several methods of combining P-values that are more advantageous than combining of OLS and GLS statistics, method B maintains nominal significance levels and is more efficient, while method F and G have type I error rates that are larger than the specified significance levels, which might occasionally lead to a wrong conclusion.

THE EFFECT OF ETCHING TIME ON SHEAR BOND STRENGTH AND ADAPTIBILITY OF ONE-BOTTLE DENTIN ADHESIVE (One-bottle 상아질 접착제의 전단결합강도와 접착성에 관한 부식시간의 효과)

  • Park, Kwang-Soo;Park, Il-Yoon;Cho, Young-Gon
    • Restorative Dentistry and Endodontics
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    • v.24 no.1
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    • pp.240-250
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    • 1999
  • The purpose of this study was to evaluate the effect of different etching time on the shear bond strength and adaptibility of composite to enamel and dentin when used one-bottle adhesive Prime & Bond$^{TM}$ 2.0. The proximal and occlusal surfaces of 88 extracted human molars were ground to expose enamel(n=44) and dentin (=44) using diamond wheel saw. Teeth were randomly assigned to four test groups(n=11) and received the following treatments : Control group were conditioned with 36% phosphoric acid for 20 sec. according to the manufacturer's directions. Experimental 10 sec. group, 30 sec. group and 60 sec. group were conditioned with 36% phosphoric acid for 10 sec., 30 sec. and 60 sec., respectively. Teeth were rinsed and dried for 2 sec. Prime & Bond$^{TM}$ 2.0 were applied according to the manufacturer's directions and Spectrum$^{TM}$ TPH composite resins were bonded to enamel and dentin surfaces. All specimens were stored in distilled water for 24 hours. Eighty specimens were sheared in a Universal Testing Machine with a crosshead speed of 5mm/minute. One way ANOVA and LSD test were used for statistical analysis of the data. Failure modes of all specimens after shear bond strength test were examined and listed. Also, representive postfracture modes and eight specimens were examined under scanning electron microscope. The results of this study were as follows: 1. The shear bond strength to enamel was the highest value in 30 sec. group (20.68${\pm}$8.54MPa) and the lowest value in 10 sec. group (14.92${\pm}$6.07MPa), so there was significant difference of shear bond strength between two groups (p<0.05). But there was no significant difference among other groups (p>0.05). With longer etching time to enamel from 10 sec. to 30 sec., higher the shear bond strength was obtained, but the shear bond strength was decreased at 60 sec. etching time. 2. The shear bond strength to dentin was the highest value in control group (13.08${\pm}$6.25MPa) and the lowest value in 60 sec. group (9.47${\pm}$3.35MPa), but there was no significant difference among the all groups (p>0.05). The eching time over 20 sec. decreased the shear bond strength to dentin. 3. In SEM observation, the enamel and resin interfaces were showed close adaptation with no relation to etching time of enamel. And the dentin and resin interfaces were showed close adaptation at 20 sec. and 30 sec. etching time, but showed some gaps at 10 sec. and 60 sec. etching time. Accordingly, these results indicated that a appropriate etching time in Prime & Bond$^{TM}$ 2.0 was required to be 30 sec. in enamel and 20 sec. in dentin for the high shear bond strength and good adaptation between the composite resin and tooth substance.

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Testing the Relationship between Person-Organizational Value Fit and Performance (개인-조직가치 부합수준과 성과관계 검증)

  • Park, Yang-Kyu;Yeo, Sung-Chil
    • The Korean Journal of Applied Statistics
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    • v.24 no.2
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    • pp.411-424
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    • 2011
  • The studies of congruence in organizational research have explored the concepts such as person-job fit person-organization fit, or person-environment fit. The relevant studies dealt with the fit level as an important influencing factor on the performance. In particular, researchers have agreed that employees can be motivated by the high level fit of person-organization. However, few research developing an alternative methodological approach has been done. For the purpose mentioned above the statistics like D, |D| or $D^2$ and the Q values such as Q(the correlation between two sets of interval measures) or $Q_r$(the correlation between two rankings) have been conventionally adopted in spite of numerous methodological problems. In general, these traditional indices such as difference scores, or Q values, are nondirectional and add an extra weight to differences of lager magnitude. Therefore, Edwards (1993) introduced the polynomial regression and the response surface analysis to overcome flaws with conventional approaches. However, the method-ological approaches did not reflect the profile characteristics of person-organizational value fit and wouldn't be a proper solution for the fit level of person-organization value maximizing performance. Hence, this paper investigates alternative methodological approaches, the multivariate polynomial regression and the multiple response surface analysis, to avoid the problems issued from conventional ways.

Relationship between Transformational Leadership and Innovative Behavior (변혁적 리더십과 조직혁신간의 관계)

  • Ko, Hyon-Sook;Kim, Jung-Hoon
    • The Journal of the Korea Contents Association
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    • v.11 no.4
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    • pp.361-377
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    • 2011
  • This study has three primary purposes, firstly to identify how leader's personal characters influence to his/her transformational leadership, secondly to find how transformational leadership influences to innovative behavior, finally to explore how organizational cultures moderate between transformational leadership and innovative behavior. The first part of the study, based on literature study on transformational leadership, provides insight into what are antecedents, moderators and dependent variable in transformational leadership. Firstly, leader's personal characters are selected as antecedent variables such as extroversion and self-efficacy. Secondly, innovative behavior is introduced as a dependent variable. Thirdly, two types of organizational culture are considered as moderators between leader's personal character and leadership In this study, a comprehensive research model and hypothesis were empirically tested based on data from three types of questionnaires involving 663 employees in Korean organizations. In order to test the hypotheses, we have used Structural Equations Model (SEM) from AMOS7.0. In this analysis, we have employed raw data as it is instead of correlation matrix or covariance matrix. We have tested hypotheses by examining the significance of each path of the model, and gone through the process of testing the goodness of fit of the model itself. The results of statistical analysis show the following. Firstly, one of leader's personalities, self-efficacy has positive effect on his/her transformational leadership, but extroversion does not have positive effect. Secondly, transformational leadership has positive effect on innovative behavior. Finally, there was not any cultural moderating effects between transformational leadership and innovative behavior.

A Study of the Quantitative, Qualitative Analysis on Optimizing Diagnostic Imaging Device Selection in Nasopharynx MRI (비 인두 자기공명 검사 시 최적의 진단영상 장치 선택에 관한 정량, 정성적 평가에 관한 연구)

  • Goo, Eun-Hoe
    • Journal of the Korean Society of Radiology
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    • v.13 no.7
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    • pp.1035-1043
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    • 2019
  • The object of is this research is to find out the optimal Tesla by evaluating SNR and CNR, after testing 1.5 T and 3.0 T. The randomly selected patients tested by nasopharynx MRI transmitted in PACS were applied to the research. Two MRI units(1.5 T, 3.0 T) was used for analyzing the data. As a method of analysis, in T1W highlighting and T1 fat removal images, we set up a certain area of interest and evaluated the SNR and CNR on tongue, spinal cord, masseter muscle, fat, parotid gland, and tumor tissue. We evaluated the SNR and CNR by quantitative analysis of six tissue, measuring the quality of images for uniform fat removal, magnetic sensitivity artifact on a four-point scale by qualitative analysis. The statistical significance of this date analysis was based on independent sample verification and was accepted when the P value was less than 0.05. As a result of analysis of both devices, 3.0 T was high in the quantitative evaluation, while 1.5 T was high in the qualitative evaluation. Considering the advantages and disadvantages of each device, and if the device is selected complementarily and applied to patients, it is believed that it will provide the optimal information.