• Journal of Society of Preventive Korean Medicine
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• v.21 no.2
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• pp.1-13
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• 2017

Objectives : This paper serves to explore current trends of systems biology in Traditional Chinese Medicine (TCM) and examine how it may influence the Traditional Korean medicine. Methods : Literature review method was collectively used to classify Introduction to systems biology, diagnosis and syndrome classification of systems biology in TCM perspective, physiotherapy including acupuncture, herbs and formula functions, TCM systems biology, and directions of academic development. Results : The term 'Systems biology' is coined as a combination of systems science and biology. It is a field of study that tries to understand living organism by establishing a theory based on an ideal model that analyzes and predicts the desired output with understanding of interrelationships and dynamics between variables. Systems biology has an integrated and multi-dimensional nature that observes the interaction among the elements constructing the network. The current state of systems biology in TCM is categorized into 4 parts: diagnosis and syndrome, physical therapy, herbs and formulas and academic development of TCM systems biology and its technology. Diagnosis and syndrome field is focusing on developing TCM into personalized medicine by clarifying Kidney yin deficiency patterns and metabolic differences among five patterns of diabetes and analyzing plasma metabolism and biomarkers of coronary heart disease patients. In the field of physical therapy such as acupuncture and moxibustion, researchers discovered the effect of stimulating acupoint ST40 on gene expression and the effects of acupuncture on treating functional dyspepsia and acute ischemic stroke. Herbs and formulas were analyzed with TCM network pharmacology. The therapeutic mechanisms of Si Wu Tang and its series formulas are explained by identifying potential active substances, targets and mechanism of action, including metabolic pathways of amino acid and fatty acid. For the academic development of TCM systems biology and its technology, it is necessary to integrate massive database, integrate pharmacokinetics and pharmacodynamics, as well as systems biology. It is also essential to establish a platform to maximize herbal treatment through accumulation of research data and diseases-specific, or drug-specific network combined with clinical experiences, and identify functions and roles of molecules in herbs and conduct animal-based studies within TCM frame. So far, few literature reviews exist for systems biology in traditional Korean medicine and they merely re-examine known efficacies of simple substances, herbs and formulas. For the future, it is necessary to identify specific mechanisms of working agents and targets to maximize the effects of traditional medicine modalities. Conclusions : Systems biology is widely accepted and studied in TCM and already advanced into a field known as 'TCM systems biology', which calls for the study of incorporating TCM and systems biology. It is time for traditional Korean medicine to acknowledge the importance of systems biology and present scientific basis of traditional medicine and establish the principles of diagnosis, prevention and treatment of diseases. By doing so, traditional Korean medicine would be innovated and further developed into a personalized medicine.

• The Journal of Engineering Geology
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• v.26 no.2
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• pp.223-233
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• 2016

This study establishes a commercialization strategy for technology that can monitor and detect landslides in real time. An effective commercialization strategy was sought through both qualitative and quantitative analyses. The qualitative analysis considered the business environment in detail, while the quantitative analysis examined technologically strong and weak areas by visualizing the links between IPC (International Patent Classification) code structure and patent applicants. The results from both analyses are considered together, with particular attention paid to the business environment. The resulting integrated analysis comprehensively explores the degree of technological development and the current state of real-time monitoring and detection technology for landslides. The integrated analysis identified complementary assets in the business environment, as there is strong development and many research entities in this area. This suggests positive reinforcement for commercialization with two sub-strategies: (1) exploring demand with complementary assets, and (2) providing technology information for explored demand, which should facilitate successful commercialization. Exploiting this positive reinforcement for technology commercialization could reduce the high uncertainty of the technology and the market, and thus increase the probability of successful commercialization. It is also expected to contribute to long-term success by strengthening collaboration between the supply and demand sides.

• Journal of Bio-Environment Control
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• v.12 no.3
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• pp.114-120
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• 2003

In order to provide fundamental data for development of controlled environment facilities in Korean ginseng (Panax ginseng C.A. Meyer) cultivation, field survey and analysis of structural and environmental engineering characteristics on the shading structures in ginseng fields (the ginseng houses) were carried out. In this study shading structures for ginseng cultivation were classified according to their structural materials, connection types, and detailed structures. That is they were classified into wood or steel frames, single or multi spans, and frame or cable types. As a result of the investigation, standardization of structural materials, fabrication and construction methods arc required. And it was considered that a reinforced design and a countermeasure for heavy snow are the most important matters for structural improvement. In parts of the environmental management, researches for setting up the irrigation standard are required in the first place. And it was investigated that an installation of the shading structures is a work being the most hard, taking a lot of time, and having need for automation. So controlled environment ginseng houses, with a low cost, a structural safety and a satisfactory workability, should be developed.

• The Journal of the Acoustical Society of Korea
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• v.24 no.4
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• pp.230-237
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• 2005

The angle-tracking of maneuvering targets is required to the state estimation and classification of targets in underwater acoustic systems. The Problem of angle-tracking multiple closed and crossing targets has been studied by various authors. Sword et al. Proposed a multiple target an91e-tracking algorithm using angular innovations of the targets during a sampling Period are estimated in the least square sense using the most recent estimate of the sensor output covariance matrix. This algorithm has attractive features of simple structure and avoidance of data association problem. Ryu et al. recently Proposed an effective multiple target angle-tracking algorithm which can obtain the angular innovations of the targets from a signal subspace instead of the sensor output covariance matrix. Hwang et al. improved the computational performance of a multiple target angle-tracking algorithm based on the fact that the steering vector and the noise subspace are orthogonal. These algorithms. however. are ineffective when a subset of the incident sources are coherent. In this Paper, we proposed a new multiple target angle-tracking algorithm for coherent and incoherent sources. The proposed algorithm uses the relationship between source steering vectors and the signal eigenvectors which are multiplied noise covariance matrix. The computer simulation results demonstrate the improved Performance of the Proposed algorithm.

• Journal of the Korean Association of Geographic Information Studies
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• v.16 no.4
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• pp.171-188
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• 2013

Landuse changes and cadastral information error categories in the four major river areas were analyzed for the use of policy data as cadastral re-arrangement of national and public lands would be required, using high-resolution air-photographs and cadastral maps before and after the river development. The study sites were the river areas of 40km around four dams of the Nakdong river where their landuses were changed most. As the results, national and public lands reached 79.9% of land parcels and 93.3% of land areas of the study sites similar with those of the four river areas, 84.3% of land parcels and 85.5% of land areas. The landuse classification of the study sites before the four river development was consisted most of 'river'(71.6%) and 'rice field'(12.3%), but after the development the 'river' was reduced to 42.7% and 'park area'(19.6%) including sport fields and 'mixed lots'(20.8%) were increased. Also, 86.7% of land parcels before the development could be reduced after the development if administrative districts and land ownerships were not considered. Cadastral information error categories can be found as cadastral polygon missing, polygon overlap, location and boundary non-coincidence, small polygon generation, and non-coincidence between cadastral boundary and river boundary. Landuse change monitoring method using air-photographs will be useful to analyze landuse state through fast information aquisition and to manage properties of national and public lands such as river areas.

• Journal of the Korean Association of Geographic Information Studies
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• v.16 no.2
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• pp.75-87
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• 2013

This study developed a GIS-based suitability assessment model of coastal zoning system that is needed in the substantial classification of coastal zoning system according to the establishment of law about coastal zoning system. First, this study investigated several kinds of regulations, GIS database and application system related coastal area. Also, grid data model was selected as the GIS analytical model for calculating items of suitability assessment of coastal zoning system. And Grid-based analytical method was suggested for calculating items composing of sea and spatial location characteristics including physical one. Critical values of items were presented using standards that were suggested in coastal regulations and land suitability assessment. Especially, this study presented a calculation method of continuous pattern as fuzzy set function for reflecting the characteristics of GIS data. And this study classified the suitability grade using Z-score and developed model designating coastal zone as conservation management priority, utilization management priority, and planning management priority. This study is judged that very efficient business performance is possible if we consider the spatial coverage of study area and GIS database when the suitability assessment model of coastal zoning system that is suggested in this study, is applied to business works.

• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.6
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• pp.126-134
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• 2015

A sleep disorder is being recognized as one of the major health issues related to high levels of stress. At the same time, interests about quality of sleep are rapidly increasing. However, diagnosing sleep disorder is not a simple task because patients should undergo polysomnography test, which requires a long time and high cost. To solve this problem, an accelerometer embedded wrist-worn device is being considered as a simple and low cost solution. However, conventional methods determine a state of user to "sleep" or "wake" according to whether values of individual section's accelerometer data exceed a certain threshold or not. As a result, a high miss-classification rate is observed due to user's intermittent movements while sleeping and tiny movements while awake. In this paper, we propose a novel method that resolves the above problems by employing a dynamic classifier which evaluates a similarity between the neighboring data scores obtained from SVM classifier. A performance of the proposed method is evaluated using 50 data sets and its superiority is verified by achieving 88.9% accuracy, 88.9% sensitivity, and 88.5% specificity.

• Journal of the Korean Geosynthetics Society
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• v.12 no.2
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• pp.13-23
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• 2013

The Korean Peninsula is considered as a seasonal frozen area that is thawed in the spring and frozen in the winter. The influence of fines of the frost susceptibility of subgrade soils were established by laboratory freezing tests simulating closely the thermal conditions in the field. During the winter season, the climate is heavily influenced by the cold and dry continental high pressure. Because of siberian air mass, the temperature of January is $-6{\sim}-7^{\circ}C$ on average. This chilly weather generate the frost heaving by freezing the moisture of soil and damage potential of the geotechnical structure. In the freezing soil, the ice lenses increase the freeze portion of soil by absorbing the ground water with capillary action. However, the capillary characteristics differ from the sort of soil on the state of freezing condition. In this study, ten soil samples are prepared. The basic physical property tests were performed by following the Korean Industrial Standard and the soil specimens were classified by the Unified Soil Classification System (USCS). These classified soils are used to perform the laboratory opened systems freezing test in order to determine the frost heaving characteristics of soils such as unfrozen water content, heaving amount, and freezing depth.

• Korean Journal of Environment and Ecology
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• v.28 no.6
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• pp.725-740
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• 2014

To figure out the vegetation situation in the ridge of the Naknam-Jeongmaek, six intensive survey sites were selected considering environmental factors and human interferences, 132 quadrats (area $100m^2$) were installed to survey appearing species of trees and major environmental factors, and the characteristics of vegetation structures were analyzed. The surveyed plots were divided into six groups according to the analysis of classification by TWINSPAN; Quercus mongolica-Q. variabilis community, Pinus densiflora-Q. dentata community, Chamaecyparis obtusa community, Q. mongolica-P. densiflora community, P. densiflora-P. thunbergii community, P. koraiensis community, Rhododendron spp.-Lespedeza cyrtobotrya community. P. densiflora-Q. dentata community, Q. mongolica-P. densiflora community, and P. densiflora-P. thunbergii community are expected to be succeeded by deciduous oaks because the power of deciduous oaks is strong in their lower layer. C. obtusa community, P. densiflora community, and Rhododendron spp.-L.cyrtobotrya community are artificial forests that were artificially formed and are expected to be maintained in the current state for some time because the dominance value of planted species of trees is high. Most vegetations in Naknam-Jeongmaek were secondary forests or artificial forests formed for forest tree production and forestation for erosion control. In particular the top regions and hilly sections of the mountain were mostly dominated by deciduous oaks such as Q. mongolica, Q. variabilis showed some P. densiflora community competing with deciduous oaks. On the other hand, low sections and regions adjacent to the city showed severe artificial interference since exotic species such as P. thunbergiil, C. obtusa, P. koraiensis, and Rhododendron spp. were planted.

• Journal of the Korea Society of Computer and Information
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• v.18 no.6
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• pp.21-28
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• 2013

This paper proposes an effective fire detection approach that includes the following multiple heterogeneous algorithms: moving region detection using grey level histograms, color segmentation using fuzzy c-means clustering (FCM), feature extraction using a grey level co-occurrence matrix (GLCM), and fire classification using support vector machine (SVM). The proposed approach determines the optimal threshold values based on grey level histograms in order to detect moving regions, and then performs color segmentation in the CIE LAB color space by applying the FCM. These steps help to specify candidate regions of fire. We then extract features of fire using the GLCM and these features are used as inputs of SVM to classify fire or non-fire. We evaluate the proposed approach by comparing it with two state-of-the-art fire detection algorithms in terms of the fire detection rate (or percentages of true positive, PTP) and the false fire detection rate (or percentages of true negative, PTN). Experimental results indicated that the proposed approach outperformed conventional fire detection algorithms by yielding 97.94% for PTP and 4.63% for PTN, respectively.