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Minimally Complex Problem Set for an Ab initio Protein Structure Prediction Study

  • Kim RyangGug;Choi Cha-Yong
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.9 no.5
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    • pp.414-418
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    • 2004
  • A 'minimally complex problem set' for ab initio protein Structure prediction has been proposed. As well as consisting of non-redundant and crystallographically determined high-resolution protein structures, without disulphide bonds, modified residues, unusual connectivities and heteromolecules, it is more importantly a collection of protein structures. with a high probability of being the same in the crystal form as in solution. To our knowledge, this is the first attempt at this kind of dataset. Considering the lattice constraint in crystals, and the possible flexibility in solution of crystallographically determined protein structures, our dataset is thought to be the safest starting points for an ab initio protein structure prediction study.

Improvement and quasi optical analysis of wide band prototype feedhorn for ASTE focal plane array

  • Lee, Bangwon;Gonzalez, Alvaro;Lee, Jung-won
    • The Bulletin of The Korean Astronomical Society
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    • v.42 no.1
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    • pp.57.1-57.1
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    • 2017
  • As an upgrade we report the current ASTE ultra-wideband corrugated horn design. The length of the feedhorn gets shortened from 12.5 mm to 11 mm, and it shows better side lobe level at the far-field patterns compared with the previous design. We looked into possible quasi-optical solution to match the feedhorn beam to the optics of the current ASTE telescope, starting from frequency-independent solution using two ellipsoidal mirrors to which wideband performance of the feedhorn naturally fits. We used a commercial physical optics package (GRASP) with an user-defined optimizer to give physical constraints to evaluated optical designs for highest efficiency.

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Formation Reaction of Mn-Zn Ferrite by Wet Process (습식합성에 의한 Mn-Zn Ferrite의 생성반응에 관한 연구)

  • 이경희;이병하;허원도;황우연
    • Journal of the Korean Ceramic Society
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    • v.30 no.1
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    • pp.25-33
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    • 1993
  • Formation reaction of Mn-Zn ferrite depending on various synthetic conditions of wet process was investigated using FeCl2.nH2O(n≒4), MnCl2.4H2O, ZnCl2 as starting materials. A stable intermediate precipitate was formed by the addition of H2O2. And the precipitate was hard to transform to spinel phase of Mn-Zn Fe2O4. Single phase of Mn-Zn Fe2O4 spinel was obtained above 8$0^{\circ}C$ reaction temperature. The powder had spherical particle shape and 0.02~0.05${\mu}{\textrm}{m}$ particle size. Fe(OH)2 solid solution, -FeO(OH) solid solution, -FeOOH, Mn-Zn Fe2O4 spinel were formed with air flow rate 180$\ell$/hr. However, single phase of Mn-Zn Fe2O4 spinel with cubic particle shape and 0.1~0.2${\mu}{\textrm}{m}$ particle size was formed with synthetic conditions of 8$0^{\circ}C$ and 90 munutes. The particle shape of the -FeOOH was needle-like.

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AN ALGORITHM FOR SOLVING THE PROBLEM OF CONVEX PROGRAMMING WITH SEVERAL OBJECTIVE FUNCTIONS

  • Cocan, Moise;Pop, Bogdana
    • Journal of applied mathematics & informatics
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    • v.6 no.1
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    • pp.79-88
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    • 1999
  • This work aims to establish an algorithm for solving the problem of convex programming with several objective-functions with linear constraints. Starting from the idea of Rosen's algorithm for solving the problem of convex programming with linear con-straints and taking into account the solution concept from multi-dimensional programming represented by a program which reaches "the best compromise" we are extending this method in the case of multidimensional programming. The concept of direction of min-imization is introduced and a necessary and sufficient condition is given for a s∈Rn direction to be a direction is min-imal. The two numerical examples presented at the end validate the algorithm.

The Photo-reproducibility and Stability of Long Chain Fatty Acid Containing Azobenzene (아조벤젠을 함유한 장쇄 지방산의 광재현성과 안정성에 관한 연구)

  • Par, Keun-Ho;Park, Tae-Gone
    • Journal of the Korean Applied Science and Technology
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    • v.12 no.1
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    • pp.109-114
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    • 1995
  • The Synthesis of long chain fatty acid containing azobenzene and $(C_{n}-Azo)$ was optimized, starting from p-(p'-hydroxy phenyl azo)-benzoic acid and the product of reaction containing azobenzene chromophores was investigated by ultraviolet spectrophotometery in chloroform solvent at the various temperature. In addition, Reversibility and stability of azo compounds have been measured by means of Ultraviolet and the structure of these compound were ascertained by means of FT-IR and NMR. Recrystallization of reaction product in the solvent results the experimental yield obtained about 62.93% p-(p'-octadecyloxy phenyl azo)-benzoic acid. Long chain azobenzene derivatives in chloroform solution are induced photoisomerization by u. v. and visible light irradiation. The solution of long chain fatty acids$(C_{n}-Azo)$ containing azobenzene are possible of being applied to functional molecular devices such as photomemory and light switching.

Studies on the Utilization of Deodorized Condensates from Vegetable Oils (植物油 脫臭溜出物의 利用에 關한 硏究)

  • Kim, Jeom Sik
    • Journal of the Korean Chemical Society
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    • v.18 no.4
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    • pp.297-303
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    • 1974
  • An investigation has been performed to find an effective separation method of steriols and tocopherols from the deodorized condensates of vegetable oils. Simple heating of the starting mixture isolated the oil layer from water, and the former was collected. It was then methyl esterified followed by a distillation for the removal of fatty acid. The ensuing step was to saponify the residue. The unsaponifiable matter was extracted by both methanol and concentrated. The sterol was crystallized by cooling such concentrated solution. To obtain tocopherol, the mother liquor was first dissolved in methanol. Cooling this solution to $-20^{\circ}C$ trapped fatty acid which was filtered out. The filtrate was then treated with ion exchange resin.

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Optimal design of composite laminates for minimizing delamination stresses by particle swarm optimization combined with FEM

  • Chen, Jianqiao;Peng, Wenjie;Ge, Rui;Wei, Junhong
    • Structural Engineering and Mechanics
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    • v.31 no.4
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    • pp.407-421
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    • 2009
  • The present paper addresses the optimal design of composite laminates with the aim of minimizing free-edge delamination stresses. A technique involving the application of particle swarm optimization (PSO) integrated with FEM was developed for the optimization. Optimization was also conducted with the zero-order method (ZOM) included in ANSYS. The semi-analytical method, which provides an approximation of the interlaminar normal stress of laminates under in-plane load, was used to partially validate the optimization results. It was found that optimal results based on ZOM are sensitive to the starting design points, and an unsuitable initial design set will lead to a result far from global solution. By contrast, the proposed method can find the global optimal solution regardless of initial designs, and the solutions were better than those obtained by ZOM in all the cases investigated.

Synthesis of NiO-doped Al2O3 Powder by Spray Pyrolysis (분무열분해법에 의한 NiO 첨가 Al2O3 분체의 합성)

  • 박정현;조경식;김한태
    • Journal of the Korean Ceramic Society
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    • v.28 no.8
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    • pp.593-602
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    • 1991
  • Al2O3 and NiO-doped Al2O3 powders were prepared from the ethanol solution of Al (NO3)3$.$9H2O and Ni(NO3)2$.$6H2O by spray pylolysis method using two-fluid nozzle. As a result of spraying test with 0.3 mol/{{{{ iota }} concentration starting solution, mean droplet sizes varied with 8.99∼9.69$\mu\textrm{m}$ and those standard deviation were 4.57∼5.12. As-prepared powders which were synthesized at 1000$^{\circ}C$ have spherical shape, sizes of 0.1∼3.0$\mu\textrm{m}$ and specific surface area of 22.34∼24.20㎡/g. Most powders consisted of {{{{ gamma }}-Al2O3 phase and transforned into ${\alpha}$-A;2O3 phase by calcination at 1100$^{\circ}C$ for 1 hr. NiO-doped Al2O3 sintered bodies had better sinterability than those of pure Al2O3 and 0.3 wt% NiO-doped Al2O3 had near theoretical density and dense microstructure.

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Effect of HPC Dispersant on Synthesis of Monodispersed Hydrated Zirconia Powder by Hydrolysis of Zr-n-butoxide (Zr(n-OC$_4$H$_9$)$_4$의 가수분해에 의한 선분산 지르코니아 분체의 합성에서 분산제 HPC의 첨가효과)

  • Rhee, Jhun;Jo, Dong-Soo
    • Journal of the Korean Ceramic Society
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    • v.28 no.8
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    • pp.611-618
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    • 1991
  • In the present study adding hydroxypropyl celluose as dispersant to the ethanol solution of Zr-butoxide prior to starting the hydrolysis reaction, spherical and submicrometer sized hydrated zirconia powders were synthesized successfully. But syntesized hydrated zirconia powders were soluble considerably in ethanol used as washing medium. Washing once the powder with plenty amount of water after washing thrice it with acetone, reaction mother solution remained between the particles was effectively removed and the particles were converted to insoluble state to ethanol at the same time. As a result of such washing processes it was able to prevent the formation of polydispersed, agglomerated and multiplet particles almost always even when such concentrated solutions of Zr-n-butoxide as 0.5 M were hydrolyzed.

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Lessons Learned and Challenges Encountered in Retail Sales Forecast

  • Song, Qiang
    • Industrial Engineering and Management Systems
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    • v.14 no.2
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    • pp.196-209
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    • 2015
  • Retail sales forecast is a special area of forecasting. Its unique characteristics call for unique data models and treatment, and unique forecasting processes. In this paper, we will address lessons learned and challenges encountered in retail sales forecast from a practical and technical perspective. In particular, starting with the data models of retail sales data, we proceed to address issues existing in estimating and processing each component in the data model. We will discuss how to estimate the multi-seasonal cycles in retail sales data, and the limitations of the existing methodologies. In addition, we will talk about the distinction between business events and forecast events, the methodologies used in event detection and event effect estimation, and the difficulties in compound event detection and effect estimation. For each of the issues and challenges, we will present our solution strategy. Some of the solution strategies can be generalized and could be helpful in solving similar forecast problems in different areas.